Estimation of Kinetic Parameters by a Hybrid Algorithm of Nonlinear Model Based Differential Evolution for Lactic Acid Production

2016 ◽  
Vol 11 (2) ◽  
pp. 141-148
Author(s):  
J. Satya Eswari
Keyword(s):  
Lactic Acid ◽  
Kinetic Model ◽  
Differential Evolution ◽  
Kinetic Parameters ◽  
Acid Production ◽  
Hybrid Algorithm ◽  
Lactic Acid Production ◽  
Model Parameters ◽  
Time Interval ◽  
Experimental Conditions

Abstract The kinetic model parameters are estimated for lactic acid production using mixed microbial consortium in batch fermentation by using different optimization methods. For every time interval concentrations are measured and formulated the parameter appraisal delinquent. Cellular progression kinetic model of exponential or logistic was verified for the effect of various substrates and lactic acid production of mixed culture. This paper proposed hybrid algorithm such as nonlinear models in conjunction with differential evolution and kinetic model. The nonlinear regression with graphical method and Nelder-Mead simplex linked kinetic model was compared with the differential evolution for parameter estimation. The optimized kinetic parameters are found to be within the range of experimental conditions for which the model is developed offers a significant enhancement of lactic acid production. From the computational results, the proposed kinetic model linked differential evolution strategy is thus found effective in exploring the input search space and optimizing the kinetic parameters.

EFFETCS OF LH AND HCG ON THE METABOLISM OF THE PREPUBERTAL RAT OVARY: STIMULATION OF AMINO ACID TRANSPORT, PROTEIN SYNTHESIS, AND GLYCOLYSIS

1975 ◽  
Vol 78 (1) ◽  
pp. 122-134 ◽  
Author(s):  
Lars Nilsson ◽  
Gunnar Selstam
Keyword(s):  
Body Weight ◽  
Lactic Acid ◽  
Amino Acid ◽  
Acid Production ◽  
Lactic Acid Production ◽  
Amino Acid Uptake ◽  
Time Interval ◽  
Acid Uptake ◽  
Rat Ovary ◽  
Stimulation Of

ABSTRACT It has earlier been reported from this laboratory that FSH can stimulate amino acid uptake, protein synthesis and glycolysis in the isolated prepubertal rat ovary. In the present investigation the effects of LH and HCG were studied. The hormones were injected to prepubertal female rats, and the ovaries were extirpated for incubation in Krebs bicarbonate buffer 120 min later. Injection of 1 μg/100 g body weight of a bovine LH preparation (NIH-LH-B8) produced a significant increase in the in vitro uptake of [14C]α-amino-isobutyric acid ([14C]AIB) and [3H]leucine as well as of the incorporation of radioactivity into the ovarian protein. Higher doses (10 and 100 μg) of NIH-LH-B8 gave only minor further increases. Lactic acid production during the incubation period was also measured as a determination of the rate of glycolysis. Lactic acid production was stimulated by the LH injections with a clear dose-response between 0.1 and 10 μg/100 g body weight. The effects of LH were also investigated with shorter intervals between the injection of the hormone and the extirpation of the ovaries. While lactic acid production was maximally stimulated at a time interval of 30 min (the shortest time interval studied), 60 min was necessary for the stimulation of amino acid uptake and amino acid incorporation into protein. Injections of HCG mimicked the effects of LH on all parameters studied.

scholarly journals Microbial Interactions between Amylolytic and Non-Amylolytic Lactic Acid Bacteria Strains Isolated during the Fermentation of Pozol

2021 ◽  
Author(s):  
Sandra Bolaños-Nuñez ◽  
Jorge A. Santiago-Urbina ◽  
Jean-Pierre Guyot ◽  
Gloria Díaz-Ruiz ◽  
Carmen Wacher
Keyword(s):  
Growth Rate ◽  
Lactic Acid ◽  
Specific Growth Rate ◽  
Kinetic Parameters ◽  
Acid Production ◽  
Specific Growth ◽  
Lactic Acid Production ◽  
Amylolytic Activity ◽  
Specific Rate ◽  
Acid Yield

Pozol is a Mexican beverage prepared from fermented nixtamalized maize dough. To contribute to understanding its complex microbial ecology, the effect of inoculating on MRS-starch pure and mixed cultures of amylolytic Sii-25124 and non-amylolytic W. confusa 17, isolated from pozol, were studied on their interactions and fermentation parameters. These were compared with L. plantarum A6, an amylolytic strain isolated from cassava. Microbial growth, kinetic parameters, amylolytic activity, lactic acid production, and hydrolysis products from starch fermentation were measured. The population dynamics were followed by qPCR. L. plantarum A6 showed higher enzymatic activity, lactic acid, biomass production, and kinetic parameters than pozol LAB in pure cultures. Mixed culture of each pozol LAB with L. plantarum A6 showed a significant decrease in amylolytic activity, lactic acid yield, specific growth rate, and specific rate of amylase production. The interaction between Sii-25124 and W. confusa 17 increased the global maximum specific growth rate (µ), the lactic acid yield from starch (Ylac/s), lactic acid yield from biomass (Ylac/x), and specific rate of lactic acid production (qlac) by 15, 30, 30, and 40%, respectively compared with the pure culture of Sii-25124. Interactions between the two strains are essential for this fermentation.

scholarly journals Unstructured kinetic model of batch fermentation of USP glycerol for lactic acid production

2015 ◽  
Vol 6 (1) ◽  
pp. 81-94 ◽  
Author(s):  
Jimy Alexander Gamboa Rueda ◽  
Víctor Alexis Lizcano González ◽  
Mario Andrés Ordoñez Supelano ◽  
José Andrés Pérez Mendoza ◽  
Carolina Guzmán Luna ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Kinetic Model ◽  
Acid Production ◽  
Batch Fermentation ◽  
Lactic Acid Production
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