Functional outcomes in relation with the progression level in young degenerative disc disease patients

Physiotherapy ◽  
2017 ◽  
Vol 24 (2) ◽  
Author(s):  
Tomasz Kuligowski ◽  
Błażej Cieślik ◽  
Zofia Nowicka

AbstractIntroduction. The aim of the study was to evaluate the functional outcomes in degenerative disc disease patients by the type of herniation. Methods. The study covered 48 individuals (28 females and 20 males) aged 18-35 years who were found with a degenerative disc disease in lumbar spine (protrusion or extrusion according to the American Society of Neuroradiology). The participants were divided into two groups by the type of herniation: the protrusion and the extrusion group. The functional outcome was assessed with the Oswestry Disability Index (ODI) questionnaire and the Numeric Rating Scale (NRS). Results. Statistically significant differences were shown in ODI scores in both groups. The extrusion group demonstrated a 7.6% higher level of functional disability related to lumbar spine pain when compared with the protrusion group. The NRS results were not statistically significant between the groups. A statistically significant difference was observed between the groups during standing position, during sleep and in sex life. Respectively a 27%, 32%, and 28% greater number of individuals in the extrusion group reported problems related to these three daily activities when compared with the protrusion group. Conclusions. Our study results revealed statistically significant differences in general ODI scores between the groups. Moreover, patients with protruded lumbar disc showed better outcomes in routine activities when compared with the extrusion group.

2017 ◽  
Vol 16 (4) ◽  
pp. 307-310
Author(s):  
Ricardo Dantas Rocha ◽  
Raphael de Rezende Pratali ◽  
Rodrigo de Luca Motta ◽  
Carlos Eduardo Gonçales Barsotti ◽  
Francisco Prado Eugenio dos Santos ◽  
...  

ABSTRACT Objective: To evaluate functional results in patients submitted to lumbar arthrodesis for the treatment of degenerative disc disease. Methods: This is a retrospective study that considered patients submitted to surgery due to degenerative disc disease, with a minimum of 12 months of postoperative follow-up. The Oswestry Disability Index (ODI) and Scoliosis Research Society-22 (SRS-22) questionnaires, including total value and domains, were considered indicators of functional outcome and quality of life. Results: Sixty-one patients (mean age 60.4 years) met the inclusion criteria and had ODI and SRS-22 data recorded. Nineteen were male and 42 female. The mean of postoperative follow-up was 29 months (12-67 months). There was no statistically significant difference in any score between sexes. The mean values obtained by the questionnaires were ODI 43.4%; SRS-22 Total 2.7; Function/Activity 2.6; Pain 2.8; Appearance 2.6; Mental Health 3.0; Satisfaction 3.4. Conclusion: The values of the surgical outcome indicators were consistent with important functional disability, although the satisfaction indicator with the treatment showed satisfied patients.


Author(s):  
Tomasz Kuligowski ◽  
Błażej Cieślik ◽  
Natalia Kuciel ◽  
Agnieszka Dębiec-Bąk ◽  
Anna Skrzek

The aim of this study was to assess the efficacy of stabilizing training for the deep core muscles of the lumbar spine in subjects with degenerative disc disease. This study was conducted on 38 participants. The participants were divided into two groups: the extrusion group (EXT, n = 17) and the protrusion group (PRO, n = 21). All the subjects underwent a four-week-long core stability exercise-based treatment (five sessions/week). Clinical outcome measures were assessed pre-intervention (pre), post-intervention (post) and four weeks after the intervention (follow-up). The primary outcome measures were the spinal range of motion (ROM; Spinal Mouse® device) and the Oswestry Disability Index (ODI). In the PRO group, the ROM decreased from 88.52° pre-intervention to 83.33° post-intervention and to 82.82° at follow-up (p = 0.01), while the ODI decreased from 16.14 points pre-intervention to 6.57 points post-intervention, with 9.42 points at follow-up (p < 0.01). In the EXT group, the ROM decreased from 81.00° pre-intervention to 77.05° post-intervention, then increased to 77.94° at follow-up (p = 0.03), while the ODI decreased from 22.58 points pre-intervention to 15.41 points post-intervention and to 14.70 points at follow-up (p < 0.001). Although the stabilizing exercise sessions improved the clinical outcomes in each group, we cannot make conclusions as to whether the type of intervertebral disc damage significantly affects the results of stabilizing exercise-based treatment.


2019 ◽  
Vol 101-B (12) ◽  
pp. 1526-1533 ◽  
Author(s):  
Peter Endler ◽  
Per Ekman ◽  
Ivan Berglund ◽  
Hans Möller ◽  
Paul Gerdhem

AimsChronic low back pain due to degenerative disc disease is sometimes treated with fusion. We compared the outcome of three different fusion techniques in the Swedish Spine Register: noninstrumented posterolateral fusion (PLF), instrumented posterolateral fusion (IPLF), and interbody fusion (IBF).Patients and MethodsA total of 2874 patients who were operated on at one or two lumbar levels were followed for a mean of 9.2 years (3.6 to 19.1) for any additional lumbar spine surgery. Patient-reported outcome data were available preoperatively (n = 2874) and at one year (n = 2274), two years (n = 1958), and a mean of 6.9 years (n = 1518) postoperatively and consisted of global assessment and visual analogue scales of leg and back pain, Oswestry Disability Index, EuroQol five-dimensional index, 36-Item Short-Form Health Survey, and satisfaction with treatment. Statistical analyses were performed with competing-risks proportional hazards regression or analysis of covariance, adjusted for baseline variables.ResultsThe number of patients with additional surgery were 32/183 (17%) in the PLF group, 229/1256 (18%) in the IPLF group, and 439/1435 (31%) in the IBF group. With the PLF group as a reference, the hazard ratio for additional lumbar surgery was 1.16 (95% confidence interval (CI) 0.78 to 1.72) for the IPLF group and 2.13 (95% CI 1.45 to 3.12) for the IBF group. All patient-reported outcomes improved after surgery (p < 0.001) but were without statistically significant differences between the groups at the one-, two- and 6.9-year follow-ups (all p ≥ 0.12).ConclusionThe addition of interbody fusion to posterolateral fusion was associated with a higher risk for additional surgery and showed no advantages in patient-reported outcome Cite this article: Bone Joint J 2019;101-B:1526–1533


2017 ◽  
Vol 11 (3) ◽  
pp. 337-347 ◽  
Author(s):  
Ande M. Jakoi ◽  
Gurpal Pannu ◽  
Anthony D'Oro ◽  
Zorica Buser ◽  
Martin H. Pham ◽  
...  

<sec><title>Study Design</title><p>Retrospective analysis of a nationwide private insurance database. Chi-square analysis and linear regression models were utilized for outcome measures.</p></sec><sec><title>Purpose</title><p>The purpose of this study was to investigate any relationship between lumbar degenerative disc disease, diabetes, obesity and smoking tobacco.</p></sec><sec><title>Overview of Literature</title><p>Diabetes, obesity, and smoking tobacco are comorbid conditions known to individually have effect on degenerative disc disease. Most studies have only been on a small populous scale. No study has yet to investigate the combination of these conditions within a large patient cohort nor have they reviewed the combination of these conditions on degenerative disc disease.</p></sec><sec><title>Methods</title><p>A retrospective analysis of insurance billing codes within the nationwide Humana insurance database was performed, using PearlDiver software (PearlDiver, Inc., Fort Wayne, IN, USA), to identify trends among patients diagnosed with lumbar disc degenerative disease with and without the associated comorbidities of obesity, diabetes, and/or smoking tobacco. Patients billed for a comorbidity diagnosis on the same patient record as the lumbar disc degenerative disease diagnosis were compared over time to patients billed for lumbar disc degenerative disease without a comorbidity. There were no sources of funding for this manuscript and no conflicts of interest.</p></sec><sec><title>Results</title><p>The total number and prevalence of patients (per 10,000) within the database diagnosed with lumbar disc degenerative disease increased by 241.4% and 130.3%, respectively. The subsets of patients within this population who were concurrently diagnosed with either obesity, diabetes, tobacco use, or a combination thereof, was significantly higher than patients diagnosed with lumbar disc degenerative disease alone (<italic>p</italic> &lt;0.05 for all). The number of patients diagnosed with lumbar disc degenerative disease and smoking rose significantly more than patients diagnosed with lumbar disc degenerative disease and either diabetes or obesity (<italic>p</italic> &lt;0.05). The number of patients diagnosed with lumbar disc degenerative disease, smoking and obesity rose significantly more than the number of patients diagnosed with lumbar disc degenerative disease and any other comorbidity alone or combination of comorbidities (<italic>p</italic> &lt;0.05).</p></sec><sec><title>Conclusions</title><p>Diabetes, obesity and cigarette smoking each are significantly associated with an increased diagnosis of lumbar degenerative disc disease. The combination of smoking and obesity had a synergistic effect on increased rates of lumbar degenerative disc disease. Patient education and preventative care is a vital goal in prevention of degenerative disc disease within the general population.</p></sec>


Spine ◽  
2014 ◽  
Vol 39 (15) ◽  
pp. E894-E901 ◽  
Author(s):  
John Lammli ◽  
M. Camden Whitaker ◽  
Alan Moskowitz ◽  
Jennifer Duong ◽  
Frank Dong ◽  
...  

2010 ◽  
Vol 69 (12) ◽  
pp. 2102-2106 ◽  
Author(s):  
Gregory Livshits ◽  
Sergey Ermakov ◽  
Maria Popham ◽  
Alex J MacGregor ◽  
Philip N Sambrook ◽  
...  

ObjectiveOsteoarthritis (OA) and osteoporosis are often considered to lie at opposite ends of a spectrum of bone phenotypes. Lumbar degenerative disc disease (LDD) may be associated with low back pain (LBP) and is similar in many ways to OA. LDD is reported in small studies to be associated with increased spine bone mineral density (BMD). The present work aimed to confirm this association in a large population sample using MRI and explore the relationship further, in particular to determine whether it is mediated genetically.MethodsA population based sample (N=908, age range 32–74 years) of UK female twins having MRI of the lumbar spine was used in this study. LDD traits and summary measures and their relationship with BMD at the lumbar spine and hip were examined using multivariate multiple regression and maximum likelihood based variance decomposition.ResultsThere was a significant positive correlation between LDD and BMD at the lumbar spine and hip, which remained significant after adjustment for confounders. Both traits were highly heritable and the associations between them were mediated genetically.ConclusionsA clear, significant and independent association of BMD at hip and lumbar spine with LDD was found which is, in part, genetically mediated. The association with the non-axial site, the hip, is of particular interest and suggests a systemic bone effect. This should encourage the search for pleiotropic genes to help in the understanding of the bone–cartilage relationship. Moreover, genetic variants identified could provide novel therapeutic targets in the management of LBP.


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