Automated diagnosis of autism: in search of a mathematical marker

2014 ◽  
Vol 25 (6) ◽  
Author(s):  
Shreya Bhat ◽  
U. Rajendra Acharya ◽  
Hojjat Adeli ◽  
G. Muralidhar Bairy ◽  
Amir Adeli

AbstractAutism is a type of neurodevelopmental disorder affecting the memory, behavior, emotion, learning ability, and communication of an individual. An early detection of the abnormality, due to irregular processing in the brain, can be achieved using electroencephalograms (EEG). The variations in the EEG signals cannot be deciphered by mere visual inspection. Computer-aided diagnostic tools can be used to recognize the subtle and invisible information present in the irregular EEG pattern and diagnose autism. This paper presents a state-of-the-art review of automated EEG-based diagnosis of autism. Various time domain, frequency domain, time-frequency domain, and nonlinear dynamics for the analysis of autistic EEG signals are described briefly. A focus of the review is the use of nonlinear dynamics and chaos theory to discover the mathematical biomarkers for the diagnosis of the autism analogous to biological markers. A combination of the time-frequency and nonlinear dynamic analysis is the most effective approach to characterize the nonstationary and chaotic physiological signals for the automated EEG-based diagnosis of autism spectrum disorder (ASD). The features extracted using these nonlinear methods can be used as mathematical markers to detect the early stage of autism and aid the clinicians in their diagnosis. This will expedite the administration of appropriate therapies to treat the disorder.

Sensors ◽  
2018 ◽  
Vol 18 (8) ◽  
pp. 2739 ◽  
Author(s):  
Rami Alazrai ◽  
Rasha Homoud ◽  
Hisham Alwanni ◽  
Mohammad Daoud

Accurate recognition and understating of human emotions is an essential skill that can improve the collaboration between humans and machines. In this vein, electroencephalogram (EEG)-based emotion recognition is considered an active research field with challenging issues regarding the analyses of the nonstationary EEG signals and the extraction of salient features that can be used to achieve accurate emotion recognition. In this paper, an EEG-based emotion recognition approach with a novel time-frequency feature extraction technique is presented. In particular, a quadratic time-frequency distribution (QTFD) is employed to construct a high resolution time-frequency representation of the EEG signals and capture the spectral variations of the EEG signals over time. To reduce the dimensionality of the constructed QTFD-based representation, a set of 13 time- and frequency-domain features is extended to the joint time-frequency-domain and employed to quantify the QTFD-based time-frequency representation of the EEG signals. Moreover, to describe different emotion classes, we have utilized the 2D arousal-valence plane to develop four emotion labeling schemes of the EEG signals, such that each emotion labeling scheme defines a set of emotion classes. The extracted time-frequency features are used to construct a set of subject-specific support vector machine classifiers to classify the EEG signals of each subject into the different emotion classes that are defined using each of the four emotion labeling schemes. The performance of the proposed approach is evaluated using a publicly available EEG dataset, namely the DEAPdataset. Moreover, we design three performance evaluation analyses, namely the channel-based analysis, feature-based analysis and neutral class exclusion analysis, to quantify the effects of utilizing different groups of EEG channels that cover various regions in the brain, reducing the dimensionality of the extracted time-frequency features and excluding the EEG signals that correspond to the neutral class, on the capability of the proposed approach to discriminate between different emotion classes. The results reported in the current study demonstrate the efficacy of the proposed QTFD-based approach in recognizing different emotion classes. In particular, the average classification accuracies obtained in differentiating between the various emotion classes defined using each of the four emotion labeling schemes are within the range of 73 . 8 % – 86 . 2 % . Moreover, the emotion classification accuracies achieved by our proposed approach are higher than the results reported in several existing state-of-the-art EEG-based emotion recognition studies.


Author(s):  
Jordi Burriel-Valencia ◽  
Ruben Puche-Panadero ◽  
Javier Martinez-Roman ◽  
Angel Sapena-Bano ◽  
Martin Riera-Guasp ◽  
...  

Induction machines drive many industrial processes, and their unexpected failure can cause heavy production losses. The analysis of the current spectrum can identify online the characteristic fault signatures at an early stage, avoiding unexpected breakdowns. Nevertheless, frequency domain analysis requires stable working conditions, which is not the case for wind generators, motors driving varying loads, etc. In these cases an analysis in the time-frequency domain -such as a spectrogram- is required for detecting faults signatures. The spectrogram is built using the short frequency Fourier transform, but its resolution depends critically on the time window used to generate it: short windows provide good time resolution, but poor frequency resolution, just the opposite than long windows. Therefore, the window must be adapted at each time to the shape of the expected fault harmonics, by highly skilled maintenance personnel. In this paper, this problem is solved with the design of a new multi-band window, which generates simultaneously many different narrow-band current spectrograms, and combines them into a single, high resolution one, without the need of manual adjustments. The proposed method is validated with the diagnosis of bar breakages during the start-up of a commercial induction motor.


2021 ◽  
Author(s):  
Afef Saihi ◽  
Hussam Alshraideh

Autism spectrum disorder ASD is a neurodevelopmental disorder associated with challenges in communication, social interaction, and repetitive behaviors. Getting a clear diagnosis for a child is necessary for starting early intervention and having access to therapy services. However, there are many barriers that hinder the screening of these kids for autism at an early stage which might delay further the access to therapeutic interventions. One promising direction for improving the efficiency and accuracy of ASD detection in toddlers is the use of machine learning techniques to build classifiers that serve the purpose. This paper contributes to this area and uses the data developed by Dr. Fadi Fayez Thabtah to train and test various machine learning classifiers for the early ASD screening. Based on various attributes, three models have been trained and compared which are Decision tree C4.5, Random Forest, and Neural Network. The three models provided very good accuracies based on testing data, however, it is the Neural Network that outperformed the other two models. This work contributes to the early screening of toddlers by helping identify those who have ASD traits and should pursue formal clinical diagnosis.


Sensors ◽  
2020 ◽  
Vol 20 (12) ◽  
pp. 3496
Author(s):  
Jiacan Xu ◽  
Hao Zheng ◽  
Jianhui Wang ◽  
Donglin Li ◽  
Xiaoke Fang

Recognition of motor imagery intention is one of the hot current research focuses of brain-computer interface (BCI) studies. It can help patients with physical dyskinesia to convey their movement intentions. In recent years, breakthroughs have been made in the research on recognition of motor imagery task using deep learning, but if the important features related to motor imagery are ignored, it may lead to a decline in the recognition performance of the algorithm. This paper proposes a new deep multi-view feature learning method for the classification task of motor imagery electroencephalogram (EEG) signals. In order to obtain more representative motor imagery features in EEG signals, we introduced a multi-view feature representation based on the characteristics of EEG signals and the differences between different features. Different feature extraction methods were used to respectively extract the time domain, frequency domain, time-frequency domain and spatial features of EEG signals, so as to made them cooperate and complement. Then, the deep restricted Boltzmann machine (RBM) network improved by t-distributed stochastic neighbor embedding(t-SNE) was adopted to learn the multi-view features of EEG signals, so that the algorithm removed the feature redundancy while took into account the global characteristics in the multi-view feature sequence, reduced the dimension of the multi-visual features and enhanced the recognizability of the features. Finally, support vector machine (SVM) was chosen to classify deep multi-view features. Applying our proposed method to the BCI competition IV 2a dataset we obtained excellent classification results. The results show that the deep multi-view feature learning method further improved the classification accuracy of motor imagery tasks.


PLoS ONE ◽  
2021 ◽  
Vol 16 (6) ◽  
pp. e0253094
Author(s):  
Md. Nurul Ahad Tawhid ◽  
Siuly Siuly ◽  
Hua Wang ◽  
Frank Whittaker ◽  
Kate Wang ◽  
...  

Autism spectrum disorder (ASD) is a developmental disability characterized by persistent impairments in social interaction, speech and nonverbal communication, and restricted or repetitive behaviors. Currently Electroencephalography (EEG) is the most popular tool to inspect the existence of neurological disorders like autism biomarkers due to its low setup cost, high temporal resolution and wide availability. Generally, EEG recordings produce vast amount of data with dynamic behavior, which are visually analyzed by professional clinician to detect autism. It is laborious, expensive, subjective, error prone and has reliability issue. Therefor this study intends to develop an efficient diagnostic framework based on time-frequency spectrogram images of EEG signals to automatically identify ASD. In the proposed system, primarily, the raw EEG signals are pre-processed using re-referencing, filtering and normalization. Then, Short-Time Fourier Transform is used to transform the pre-processed signals into two-dimensional spectrogram images. Afterward those images are evaluated by machine learning (ML) and deep learning (DL) models, separately. In the ML process, textural features are extracted, and significant features are selected using principal component analysis, and feed them to six different ML classifiers for classification. In the DL process, three different convolutional neural network models are tested. The proposed DL based model achieves higher accuracy (99.15%) compared to the ML based model (95.25%) on an ASD EEG dataset and also outperforms existing methods. The findings of this study suggest that the DL based structure could discover important biomarkers for efficient and automatic diagnosis of ASD from EEG and may assist to develop computer-aided diagnosis system.


2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Yu Wang

To implement a mature music composition model for Chinese users, this paper analyzes the music composition and emotion recognition of composition content through big data technology and Neural Network (NN) algorithm. First, through a brief analysis of the current music composition style, a new Music Composition Neural Network (MCNN) structure is proposed, which adjusts the probability distribution of the Long Short-Term Memory (LSTM) generation network by constructing a reasonable Reward function. Meanwhile, the rules of music theory are used to restrict the generation of music style and realize the intelligent generation of specific style music. Afterward, the generated music composition signal is analyzed from the time-frequency domain, frequency domain, nonlinearity, and time domain. Finally, the emotion feature recognition and extraction of music composition content are realized. Experiments show that: when the iteration times of the function increase, the number of weight parameter adjustments and learning ability will increase, and thus the accuracy of the model for music composition can be greatly improved. Meanwhile, when the iteration times increases, the loss function will decrease slowly. Moreover, the music composition generated through the proposed model includes the following four aspects: sadness, joy, loneliness, and relaxation. The research results can promote music composition intellectualization and impacts traditional music composition mode.


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