Acridone Alkaloids and Coumarins from the Stem Bark of Citropsis articulata (Rutaceae)

2010 ◽  
Vol 65 (4) ◽  
pp. 525-527 ◽  
Author(s):  
Luc Mbaze Meva’a ◽  
Jules Lobe Songue ◽  
Jean Duplex Wansi ◽  
Alain François Kamdem Waffo ◽  
Etienne Dongo ◽  
...  
Keyword(s):  
Nmr Spectra ◽  
2D Nmr ◽  
Stem Bark ◽  
Mass Spectrometric ◽  
Meoh Extract ◽  
Mass Spectrometric Data ◽  
Spectrometric Data ◽  
Acridone Alkaloids ◽  
2D Nmr Spectra ◽  
Acridone Alkaloid

A new acridone alkaloid, citropsine A (1), and thirteen known compounds (2 - 14) were isolated from the MeOH extract of the stem bark of Citropsis articulata. Structures of all compounds were determined by detailed analyses of their 1D and 2D NMR spectra, mass spectrometric data and by comparison with previously known analogs.

scholarly journals New Alkaloid from Aspidosperma Polyneuron Roots

2008 ◽  
Vol 3 (2) ◽  
pp. 1934578X0800300
Author(s):  
Tatiane Alves dos Santos ◽  
Dalva Trevisan Ferreira ◽  
Jurandir Pereira Pinto ◽  
Milton Faccione ◽  
Raimundo Braz-Filho
Keyword(s):  
Nmr Spectra ◽  
Chemical Shifts ◽  
Preliminary Investigation ◽  
Ethanolic Extract ◽  
2D Nmr ◽  
Artemia Salina ◽  
Mass Spectrometric ◽  
Mass Spectrometric Data ◽  
Spectrometric Data ◽  
2D Nmr Spectra

The roots of Aspidosperma polyneuron, family Apocynaceae, were subjected to chemical and biological investigations. From an ethanolic extract of the roots, the new alkaloid 2,7-dihydroxyquebrachamine (1) was isolated. The structure was established mainly from 1D and 2D NMR spectroscopic and mass spectrometric data. The 1D and 2D NMR spectra were also used to assign all the 1H and 13C chemical shifts of this alkaloid. Artemia salina was used for a preliminary investigation of biological activity.

Pentacyclic Triterpenes and Other Constituents from Ficus cordata (Moraceae)

2008 ◽  
Vol 63 (11) ◽  
pp. 1335-1338 ◽  
Author(s):  
Herve M. P. Poumale ◽  
Rodrigue T. Kengap ◽  
Jean Claude Tchouankeu ◽  
Felix Keumedjio ◽  
Hartmut Laatsch ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Secondary Metabolites ◽  
Betulinic Acid ◽  
Nmr Spectra ◽  
2D Nmr ◽  
Stem Bark ◽  
Published Data ◽  
Pentacyclic Triterpenes ◽  
2D Nmr Spectra ◽  
Lupeol Acetate

Abstract Two new pentacyclic triterpenes 8,26-cyclo-urs-21-en-3β, 20β-diol (1) and 3β-acetoxy-8.26- cyclo-ursan-20β-ol (2) together with 3-friedelanone, oleanolic acid, betulinic acid, lupeol acetate, α- and β-amyrine, S.SJ^'-tetrahydroxyflavane, and 3,5,7,3',4'-pentahydroxyflavane were isolated from the stem bark of Ficus cordata (Moraceae). The structures of these secondary metabolites were established using ID and 2D NMR spectra and by comparison with published data or with authentic samples. Compounds 1 and 2 exhibited weak antibacterial and no antifungal activity.

scholarly journals A Phenethyl bromo ester from Citharexylum fruticosum

2010 ◽  
Vol 5 (3) ◽  
pp. 1934578X1000500
Author(s):  
Seru Ganapaty ◽  
Desaraju Venkata Rao ◽  
Steve Thomas Pannakal
Keyword(s):  
High Resolution ◽  
Structure Elucidation ◽  
Stem Bark ◽  
Mass Spectrometric ◽  
Mass Spectrometric Data ◽  
Spectrometric Data ◽  
High Resolution Mass ◽  
Resolution Mass

A new compound, (2 S)- p-hydroxyphenethyl 2-bromo-2-methyldodeconate (1) and 7,3′-dimethoxy-5,4′-dihydroxy flavone, together with lupeol and stigmasterol were isolated from the stem bark of Citharexylum fruticosum (Verbenaceae). The structures of the compounds were established on the basis of the interpretation of NMR (1H, 13C, COSY and HMBC) spectra, as well as low and high-resolution mass spectrometric data. In this paper, we report on the structure elucidation of 1.

scholarly journals Antialactone: A New γ-Lactone from Antiaris Africana, and its Absolute Configuration Determined from TDDFT CD Calculations

2008 ◽  
Vol 3 (2) ◽  
pp. 1934578X0800300 ◽  
Author(s):  
Vouffo Bertin ◽  
Hidayat Hussain ◽  
Simeon F. Kouam ◽  
Etienne Dongo ◽  
Gennaro Pescitelli ◽  
...  
Keyword(s):  
Natural Product ◽  
Absolute Configuration ◽  
Betulinic Acid ◽  
Spectroscopic Data ◽  
Nmr Spectra ◽  
2D Nmr ◽  
Stem Bark ◽  
Cd Spectra ◽  
2D Nmr Spectra ◽  
First Time

Four compounds were isolated from the stem bark of Antiaris africana. One of them, a γ-lactone named antialactone (1a), is reported for the first time as a natural product. The structures were determined by comprehensive analyses of their 1D and 2D NMR spectra and EI MS data. The absolute configuration of antialactone acetate (1b) was established by TDDFT CD calculations and comparison with measured CD spectra. The remaining three known compounds were identified, by comparing their spectroscopic data with those reported in the literature, as lichenxanthone, β-sitosterol, and betulinic acid.

scholarly journals Monanchomycalin C, a New Pentacyclic Guanidine Alkaloid from the Far-Eastern Marine Sponge Monanchora Pulchra

2013 ◽  
Vol 8 (10) ◽  
pp. 1934578X1300801 ◽  
Author(s):  
Ksenya M. Tabakmakher ◽  
Vladimir A. Denisenko ◽  
Alla G. Guzii ◽  
Pavel S. Dmitrenok ◽  
Sergey A. Dyshlovoy ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Marine Sponge ◽  
Human Breast Cancer ◽  
2D Nmr ◽  
Mass Spectrometric ◽  
Cytotoxic Activities ◽  
Human Breast ◽  
Mass Spectrometric Data ◽  
Spectrometric Data ◽  
Far Eastern

A new pentacyclic guanidine alkaloid, monanchomycalin C (1), along with the earlier known ptilomycalin A (2), were isolated from the Far-Eastern marine sponge Monanchora pulchra. The structure of 1 was elucidated using 1D and 2D NMR spectroscopic and mass spectrometric data. Compounds 1 and 2 exhibited cytotoxic activities against human breast cancer MDA-MB-231 cells with IC50 values of 8.2 μM and 4.3 μM, respectively.

scholarly journals Prenylated Pterocarpanes from Erythrina melanacantha

2010 ◽  
Vol 5 (5) ◽  
pp. 1934578X1000500 ◽  
Author(s):  
Wera Hauschild ◽  
Patrick B. Chalo Mutiso ◽  
Claus M. Passreiter
Keyword(s):  
Nmr Spectra ◽  
2D Nmr ◽  
Stem Bark ◽  
2D Nmr Spectra

The stem bark of Erythrina melanacantha ssp. melanacantha Taub. ex Harms. afforded one new and five known prenylated pterocarpanes (phaseollin, isoneorautenol, erybraedin A, phaseollidin, and homoedudiol). The new compound was identified as 2’,3’-epoxy-homoedudiol [3-hydroxy-8-(3,3-dimethyl-oxiranyl-methyl)pterocarpane]. All structures were elucidated by interpretation of their 1D and 2D NMR spectra.

scholarly journals Phosphonic Acid Anhydrides [RPO2]n: Oligomerization and Structure

1995 ◽  
Vol 50 (6) ◽  
pp. 855-858 ◽  
Author(s):  
Stefan Fuchs ◽  
Hubert Schmidbaur
Keyword(s):  
General Formula ◽  
Phosphonic Acid ◽  
Nmr Spectra ◽  
Mass Spectrometric ◽  
Phosphonic Acids ◽  
Mass Spectrometric Data ◽  
Spectrometric Data ◽  
Acid Anhydrides

The phosphonic acid anhydrides of the general formula [RPO2]n have been prepared with R = Me, Et, i-Pr, t-Bu, and Ph from the corresponding phosphonic acids and their chlorides and esters. Mass spectrometric data indicate that the trimers are the dominant oligomers for all five systems. According to their NMR spectra, the methyl and t-butyl compounds have a symmetrical (C3v) structure with equivalent RP groups, while the ethyl, i-propyl and phenyl homologues have the Cs structure with non-equivalent PR groups in the ratio 1:2.

Laurentixanthone C: A New Antifungal and Algicidal Xanthone from Stem Bark of Vismia laurentii

2007 ◽  
Vol 62 (4) ◽  
pp. 565-568 ◽  
Author(s):  
Michel F. Tala ◽  
Karsten Krohn ◽  
Hidayat Hussain ◽  
Simeon F. Kouamc ◽  
Hippolyte K. Wabo ◽  
...  
Keyword(s):  
Bacillus Megaterium ◽  
Nmr Spectra ◽  
2D Nmr ◽  
Stem Bark ◽  
Spectroscopic Studies ◽  
Chlorella Fusca ◽  
Gram Positive ◽  
Preliminary Results ◽  
Gram Positive Bacteria ◽  
2D Nmr Spectra

Laurentixanthone C (1), a new xanthone, was isolated from the stem bark of Vismia laurentii (Guttiferae or Clusiaceae), in addition to the known compounds vismiaquinone (2), bisvismiaquinone (3), and dammaradienol (4). The structures were established based on spectroscopic studies, notably of the 2D NMR spectra. Preliminary results showed that 1 is algicidal and strongly antibacterial against the Gram-positive bacteria Bacillus megaterium and Chlorella fusca, respectively.

scholarly journals A New Aggreceride Analogue and a Peltogynoid Isolated from the Stem Bark of Entada abyssinica (Fabaceae)

2014 ◽  
Vol 9 (10) ◽  
pp. 1934578X1400901
Author(s):  
Raduis Melong ◽  
Deccaux G. F. W. Kapche ◽  
Michel T. Feussi ◽  
Hartmut Laatsch
Keyword(s):  
Nmr Spectra ◽  
Reference Data ◽  
High Resolution Mass Spectrometry ◽  
Optical Rotation ◽  
2D Nmr ◽  
Stem Bark ◽  
Mass Spectrometry Data ◽  
Related Data ◽  
2D Nmr Spectra ◽  
New Compounds

A new monoglyceride, 1′,26′-bis-[( S)-2,3-dihydroxypropyl] hexacosanedioate (1a) and the new peltogynoid, entadanin (3), along with eight known compounds, were isolated from the stem bark of Entada abyssinica (Fabaceae). The structures of the new compounds were determined by detailed analyses of 1D and 2D NMR spectra, in combination with high-resolution mass spectrometry data, and by comparison with related data from the literature. The stereochemistry of 1a was derived by comparison of the optical rotation with reference data. Peltogynoids have been reported previously from other Fabaceae, however this is the first report of a peltogynoid from the genus Entada.

scholarly journals Normonanchocidins A, B and D, New Pentacyclic Guanidine Alkaloids from the Far-Eastern Marine Sponge Monanchora pulchra

2015 ◽  
Vol 10 (6) ◽  
pp. 1934578X1501000 ◽  
Author(s):  
Ksenya M. Tabakmakher ◽  
Tatyana N. Makarieva ◽  
Vladimir A. Denisenko ◽  
Alla G. Guzii ◽  
Pavel S. Dmitrenok ◽  
...  
Keyword(s):  
Marine Sponge ◽  
Hela Cells ◽  
2D Nmr ◽  
Mass Spectrometric ◽  
Cytotoxic Activities ◽  
Human Leukemia ◽  
Mass Spectrometric Data ◽  
Spectrometric Data ◽  
Guanidine Alkaloids ◽  
Far Eastern

New pentacyclic guanidine alkaloids, normonanchocidins A, B and D (1–3) along with the earlier known monanchocidin A were isolated from the Far-Eastern marine sponge Monanchora pulchra. Structures of 1–3 were elucidated using 1D- and 2D-NMR spectroscopic and mass spectrometric data. Compound 1 and a mixture of 2 and 3 (1:1) exhibited cytotoxic activities against human leukemia THP-1 cells with IC50 values of 2.1 μM and 3.7 μM, respectively, and against cervix epithelial carcinoma HeLa cells with IC50 of 3.8 μM and 6.8 μM, respectively.

Sign in / Sign up

Export Citation Format

Share Document