scholarly journals Local Delivery of Hyaluronan as an Adjunct to Scaling and Root Planing in the Treatment of Chronic Periodontitis

2016 ◽  
Vol 8 (1) ◽  
pp. 12-18
Author(s):  
Shyam Sunder Salavadhi ◽  
Srikanth Chintalapani ◽  
Chandra Mohan Pabolu ◽  
Arpita Paul ◽  
Ramesh Babu Mutthineni ◽  
...  
Keyword(s):  
Chronic Periodontitis ◽  
Test Group ◽  
Local Application ◽  
Control Group ◽  
Scaling And Root Planing ◽  
Plaque Score ◽  
Treatment Comparison ◽  
Root Planing ◽  
Probing Depth ◽  
The Difference

Background and aims. The present study was carried out to evaluate the adjunctive effect of local application of hyaluronan gel with scaling and root planing in the treatment of chronic periodontitis. Materials and methods. Twelve patients with chronic periodontitis participated in the study with a split-mouth design. Plaque formation and bleeding on probing (BOP) were evaluated at baseline and at 1st, 4th and 12th weeks postoperatively. Probing depth (PD) and clinical attachment levels (CAL) were evaluated at baseline and at 12-week postoperative interval. 0.2 mL of 0.8% hyaluronan gel was administered subgingivally in the test sites at baseline and after 1 week. Results. The test group exhibited a significantly lower mean plaque score and mean BOP as compared to the control group at 1st, 4th and 12th weeks (P < 0.05). Between the two groups, post-treatment comparison at 12th week showed lower PD value in the test group as compared to the control group and higher gain in CAL in the test group as compared to the control group. The difference between the two groups was statistically significant (P < 0.05). Conclusion. Local application of hyaluronan gel in conjunction with SRP might have a beneficial effect in patients with chronic periodontitis.

scholarly journals Laser Assisted Non-surgical Periodontal Therapy: A Double Blind, Randomized Clinical Trial

2017 ◽  
Vol 11 (1) ◽  
pp. 79-90 ◽  
Author(s):  
Joseph D. Everett ◽  
Jeffrey A. Rossmann ◽  
David G. Kerns ◽  
Ibtisam Al-Hashimi
Keyword(s):  
Laser Therapy ◽  
Chronic Periodontitis ◽  
Test Group ◽  
Control Group ◽  
Scaling And Root Planing ◽  
Clinical Attachment Level ◽  
Laboratory Parameters ◽  
Root Planing ◽  
Significant Difference ◽  
Attachment Level

The objective of this study was to examine potential benefits of using laser therapy for secular decontamination in conjunction with scaling and root planing in the treatment of chronic periodontitis. The study was performed on 173 teeth in 14 patients in a split-mouth design, one side received scaling and root planing followed by laser therapy using a carbon dioxide (CO2) laser with an ablative handpiece (test group); the contralateral side received scaling and root planing without laser (control group). Clinical and laboratory parameters were evaluated prior to treatment and at 3 and 6 months following therapy; clinical measurements were performed by two blinded examiners. The clinical parameters included measurement of gingival recession (REC), bleeding on probing (BOP), clinical attachment level (CAL), pocket depth (PD), furcation involvement (FUR), and tooth mobility (MOB). Laboratory testing to determine the levels of periodontal pathogens was performed using PCR techniques. The results of the study revealed statistically significant differences in clinical and laboratory parameters at 3 and 6 months after therapy for both test and control groups, but no significant difference was observed between the two groups. However, sites receiving laser therapy tended to show a greater decrease in probing depths, gain in clinical attachment level, and reduced bacterial levels. In conclusion, the overall results of the study suggest a potential benefit of using laser therapy in conjunction with scaling and root planing for the treatment of chronic periodontitis.

scholarly journals The effect of carbonate apatite membrane gelatin application on IL-1β level gingival crevicular fluid in chronic periodontitis patients

2019 ◽  
Vol 31 (3) ◽  
pp. 184
Author(s):  
Indra Mustika Setia Pribadi ◽  
Ina Hendiani ◽  
Reynaldy Sartiono
Keyword(s):  
Chronic Periodontitis ◽  
Gingival Crevicular Fluid ◽  
Test Group ◽  
Wilcoxon Test ◽  
Periodontal Pocket ◽  
Control Group ◽  
Carbonate Apatite ◽  
Scaling And Root Planing ◽  
Root Planing ◽  
Crevicular Fluid

Introduction: Apatite carbonate material plays an important role in bone tissue regeneration. The use of this membrane is expected to achieve better treatment success than those without additional therapy. The antimicrobial content in the apatite carbonate membrane can be used to support periodontal treatment of chronic periodontitis after scaling and root planing. The purpose of this research was to analyse the effect of carbonate apatite membrane gelatin application on the IL-1β level of the gingival crevicular fluid in chronic periodontitis patients. Methods: This research was a double-blind, randomised controlled trial method, with purposive sampling, and split-mouth design. The parameter was the IL-1β level in the gingival crevicular fluid before and after scaling and root planing. Carbonate apatite membrane gelatin was applied to the periodontal pocket on the test group after scaling and root planing. Data were analysed by the Wilcoxon test with a p-value < 0.05. Results: The reduction of IL-1β level gingival crevicular fluid on day-0 and day-30 on both groups showed significant value (p < 0.001). However, it showed no significant differences statistically, between the test group and the control group. Conclusion: Carbonate apatite membrane gelatin application might reduce the IL-1β level of the gingival crevicular fluid, but not showing a better reduction from the control group.Keyword: Carbonate apatite membrane gelatin, IL-1β, periodontal therapy

Evaluation of Subantimicrobial Dose Doxycycline as an Adjunct to Scaling and Root Planing in Chronic Periodontitis Patients with Diabetes: A Randomized, Placebo-Controlled Clinical Trial

2010 ◽  
Vol 11 (3) ◽  
pp. 9-16 ◽  
Author(s):  
Satish Gupta ◽  
Manohar L. Bhongade ◽  
Vikas Deo ◽  
Ritika Jaiswal
Keyword(s):  
Clinical Trial ◽  
Chronic Periodontitis ◽  
Test Group ◽  
Control Group ◽  
Controlled Clinical Trial ◽  
Diabetic Patients ◽  
Scaling And Root Planing ◽  
Pocket Depth ◽  
Root Planing ◽  
Patients With Diabetes

Abstract Aim Diabetic patients have more severe periodontal destruction, but periodontal therapy can improve metabolic control. Recently, interest has focused on the use of subantimicrobial dose doxycycline (SDD) as a treatment paradigm. Therefore, this study was undertaken to evaluate clinical efficacy of SDD with scaling and root planning (SRP) in chronic periodontitis patients with diabetes. Methods and Materials Twenty chronic periodontitis patients with diabetes mellitus were randomly allocated to either a test and a control group. Clinical measurements were recorded at baseline and at six months for probing pocket depth (PPD), clinical attachment level (CAL), and gingival recession (GR). After SRP, patients in the test group were instructed to take SDD 20-mg capsules twice a day while patients in the control group took a placebo twice a day. Both groups were on this regimen for a six-month period. Results A greater reduction in mean PPD was demonstrated in patients in the test group compared to the control group. The mean CAL increase observed in the test group was significantly greater (0.67 mm) than that in the control group. Conclusion It can be concluded that SRP, in conjunction with the SDD therapy described, is more effective then SRP alone in terms of CAL gain and PPD reduction in diabetic patients with severe periodontal disease. Clinical Significance Given the widespread prevalence of both chronic periodontitis and diabetes, the proposed treatment approach will prove to be of great value and contribute significantly to the overall health of the patients. Citation Deo V, Gupta S, Bhongade ML, Jaiswal R. Evaluation of Subantimicrobial Dose Doxycycline as an Adjunct to Scaling and Root Planing in Chronic Periodontitis Patients with Diabetes: A Randomized, Placebo-Controlled Clinical Trial. J Contemp Dent Pract [Internet]. 2010 May; 11(3):009-016. Available from: http://www.thejcdp.com/journal/view/volume11- issue3-deo.

scholarly journals Systemic Lycopene as an adjunct to Non-Surgical Periodontal Therapy in Generalized Chronic Periodontitis

2021 ◽  
Vol 12 (1) ◽  
pp. 115-119
Author(s):  
Shilpa Kamra ◽  
Amit Bhardwaj ◽  
Geetanjali Arora
Keyword(s):  
Chronic Periodontitis ◽  
Test Group ◽  
Mean Value ◽  
Control Group ◽  
P Value ◽  
Scaling And Root Planing ◽  
Once Daily ◽  
Reactive Protein ◽  
Root Planing ◽  
Promising Treatment

Aim: To evaluate the potency of systemic anti-oxidants in the non-surgical treatment of generalised chronic periodontitis. Objective: Purpose of this short term clinical study is to ascertain whether or not daily systemic supplementation of antioxidants adjunctively used after scaling and root planing (SRP) would improve clinical condition in generalised chronic periodontitis using C-reactive protein (CRP) as inflammatory markers and chronic periodontitis treatment index needs (CPTIN Index) to evaluate reduction in periodontal pockets. Results: Each group involved 10 participants with age group 30-65 years. The test group was provided with treatment with 20 mg Lycopene once daily after 24 hours of completion of scaling and root planing. The CRP value at baseline ranged from 3- 6.2 with a mean value of 4.87± 1.09. After one month of treatment, the CRP value ranges between 1.1- 4.8 with a mean value of 3.10 ± 1.05. This clearly indicates a significant decrease in CRP with t value 10.83 and >0.00 p value. The CRP value of control group at baseline ranged from 3-5.9 with a mean value of 4.58± 1.08. After one month of treatment with scaling and root planing, the CRP value ranges to 2.2- 5.4 with a mean value of 3.96 ± 1.08. This clearly indicates a significant decrease in CRP with t value 13.29 and > 0.00 p value. Conclusion: Lycopene as an antioxidant is a promising treatment modality as an adjunct to full mouth scaling. It helps to modulate oxidative stress in periodontium during periodontitis. It also leads to maintenance of periodontal health. 

scholarly journals Evaluation of non-surgical therapy on glutathione levels in chronic periodontitis

2015 ◽  
Vol 09 (03) ◽  
pp. 415-422 ◽  
Author(s):  
Pooja Palwankar ◽  
Minakshi Rana ◽  
Kapil Arora ◽  
C. Deepthy
Keyword(s):  
Chronic Periodontitis ◽  
Gingival Crevicular Fluid ◽  
Test Group ◽  
Redox Balance ◽  
Control Group ◽  
Scaling And Root Planing ◽  
Root Planing ◽  
Nonsurgical Periodontal Therapy ◽  
Student’S T ◽  
Crevicular Fluid

ABSTRACT Objective: To compare the levels of glutathione (GSH), both oxidized and reduced forms in patients with and without chronic periodontitis in gingival crevicular fluid (GCF). Materials and Methods: Twenty GCF samples from maxillary quadrants were collected using capillary micropipettes from the chronic periodontitis patients (test group) at baseline before treatment, at 1-month, 3 months, and 6 months after scaling and root planing and samples from 20 patients without chronic periodontitis (control group) from maxillary quadrants were also collected. GSH, oxidized glutathione (GSSG) levels and GSH: GSSG ratios were determined using the spectrophotometric method. Statistical Analysis: Results were concluded for the test over control groups using paired Student's t-test. Results: Lower concentrations of GSH (P < 0.001) and GSSG (P < 0.001) were detected in GCF in patients with chronic periodontitis (test group) than patients without chronic periodontitis (control group) at baseline. Treatment had a significant effect in improving the GSH and reducing GSSG levels postscaling and root planing at 1-month and 3 months but not significant effect at 6 months. Scaling and root planing increased the GSH: GSSG ratio (P < 0.001) in the test group as compared to the control group (P < 0.001). Conclusions: The concentrations of GSH within GCF are reduced in chronic periodontitis patients. Scaling and root planing (nonsurgical therapy) restores GSH concentration in GCF post 1-month and 3 months along with redox balance (GSH: GSSG ratio), but at 6 months the balance is not maintained. Adjunctive use of micronutritional supplements to boost antioxidant concentration in tissues by preserving GSH or by elevating its level at the inflamed sites is recommended, as nonsurgical periodontal therapy alone is not able to maintain redox balance for longer duration.

scholarly journals METRONIDAZOLE (1%) AND CHLORHEXIDINE (0.25%) GEL AS AN ADJUNCT TO SCALING AND ROOT PLANING IN THE TREATMENT OF MODERATE TO SEVERE CHRONIC PERIODONTITIS—A CLINICAL STUDY.

2019 ◽  
Vol 8 (3) ◽  
Author(s):  
Dr Huda Hussain ◽  
Prof.(Dr.) Suhail Majid Jan ◽  
Dr. Roobal Behal
Keyword(s):  
Chronic Periodontitis ◽  
Antimicrobial Agents ◽  
Scaling And Root Planing ◽  
Gingival Index ◽  
Periodontal Health ◽  
Root Planing ◽  
Probing Depth ◽  
The Difference ◽  
Bleeding Score ◽  
And Control

Metronidazole and Chlorhexidine are commonly employed antimicrobial agents in the antinfective stage of periodontal therapy, used with the aim to achieve complete eradication of the pathogenic flora from the subgingival niches, in conjunction with professional debridement. This study was aimed to determine the adjunctive effect of a novel combination of metronidazole (1%) and chlorhexidine (0.25%) in a gel form for management of moderate to severe chronic periodontitis. Twenty subjects were included for a split mouth prospective study. Gingival index, Plaque Index, Bleeding scores and Probing depth were noted at baseline, 2 weeks and 1 month after scaling and root planing with or without an additional subgingival delivery of the antimicrobial gel. An improvement of periodontal health was seen after therapy, and the difference between the test and control sites was significant for sites with an initial probing depth of 6-8mm. However, for deeper pockets (>8mm) the difference was statistically non-significant. The reduction in bleeding score was sustained at the test sites throughout the study period. It was concluded that the adjunctive use of metronidazole (1%) and chlorhexidine (0.25%) gel could provide clinical benefit for the management of deep pockets uptil 8mm of initial probing depth.

scholarly journals Short-term results in evaluating a gingiva-adhesive hydrophobic-chlorhexidine-gel for chronic periodontitis

2014 ◽  
Vol 87 (3) ◽  
pp. 186-191
Author(s):  
Ciprian Sarbu ◽  
Darian Rusu ◽  
Horia Călniceanu ◽  
Adrian Kasaj ◽  
Stefan Adrian Petrutiu ◽  
...  
Keyword(s):  
Oral Hygiene ◽  
Chronic Periodontitis ◽  
Test Group ◽  
Study Groups ◽  
Plaque Index ◽  
Control Group ◽  
Scaling And Root Planing ◽  
Pocket Depth ◽  
Root Planing ◽  
Chlorhexidine Gel

Background and Aims: Oral mucosa and interproximal spaces of the teeth could favor the colonization of periodontopathogenic bacteria, which could be targeted by chemical antiplaque agents such as chlorhexidine, present in different oral hygiene products, thus improving the control of biofilm growth and delaying microbial accumulation. The study aimed to evaluate whether the use of a hydrophobic gel with good gingival adhesion for 14 days after the scaling and root planing of patients with chronic periodontitis would improve the treatment outcome, when compared with the use of a regular hydrophyllic gel.Material and Methods: Patients with moderate disease were included in two study groups. At baseline and 3 months after the treatment the following parameters were recorded: pocket depth, Approximal Plaque Index, Modified Gingival Index, Simplified Oral Hygiene Index, bleeding on probing. Patients received scaling and root planing in two sessions at 24 hours interval. After the treatment, patients in the test group applied the hydrophobic adhesive chlorhexidine gel once a day, every other day, while in the control group the gel was used twice daily.Results. Both treatments resulted in significant improvement in all clinical indices, except Approximal Plaque Index, which deteriorated significantly in both groups. Three months after mechanical treatment, the mean probing depth changed in the test group from 4.16±0.45 mm to 2.80±0.42 mm, and in the control group from 4.16±0.30 to 2.69±0.19.Conclusions: Both adjunctive anti-infective therapies induced clinical improvement 3 months from baseline. The differences between the two treatments were not statistically significant.

scholarly journals Clinical and microbiological effects of adjunctive photodynamic diode laser therapy in the treatment of chronic periodontitis: A randomized clinical trial

2020 ◽  
Vol 14 (3) ◽  
pp. 191-197
Author(s):  
Sahana Mallineni ◽  
Sreenivas Nagarakanti ◽  
Sumanth Gunupati ◽  
Ramesh Reddy BV ◽  
Mahaboob V Shaik ◽  
...  
Keyword(s):  
Chronic Periodontitis ◽  
Scaling And Root Planing ◽  
Invasive Treatment ◽  
Non Invasive ◽  
Root Planing ◽  
Probing Depth ◽  
Tissue Healing ◽  
Significant Difference ◽  
Bactericidal Effects ◽  
Microbiological Parameters

Background. Conventional mechanical debridement alone cannot eliminate bacteria and their products from periodontal pockets. Adjunctive therapies improve tissue healing through detoxification and bactericidal effects. Photodynamic therapy (PDT) is a non-invasive treatment procedure that involves the use of a dye as a photosensitizer to attach to the target cell and be activated by a photon of an appropriate wavelength. This study aimed to assess the effectiveness of PDT in treating periodontitis as an adjunct to scaling and root planing. Methods. Fifteen subjects with chronic periodontitis were treated randomly with scaling and root planing (SRP), followed by a single PDT (test) or SRP (control) episode alone. Full-mouth plaque index (PI), sulcus bleeding index (SBI), probing depth (PD), and clinical attachment level (CAL) were assessed at baseline and 1-month and 3-month intervals. Microbiological evaluation of Porphyromonas gingivalis (Pg) in subgingival plaque samples was performed using a commercially available real-time polymerase chain reaction. Results. The results revealed a significant difference in PI, SBI, PD, CAL, and microbiological parameters between the groups one and three months after treatment. Conclusion. A combination of PDT and SRP gave rise to a significant improvement in clinical and microbiological parameters in patients with chronic periodontitis.

scholarly journals COMPARATIVE EVALUATION OF EFFICACY OF SCALING AND ROOT PLANING WITH AND WITHOUT CHLORHEXIDINE CHIP AND DIODE LASER IN CHRONIC PERIODONTITIS PATIENTS

2021 ◽  
Vol 5 (11) ◽  
Author(s):  
Reya Shree ◽  
Varun Dahiya ◽  
Pradeep Shukla ◽  
Prerna Kataria ◽  
Mona Dagar
Keyword(s):  
Diode Laser ◽  
Chronic Periodontitis ◽  
Control Group ◽  
Clinical Parameters ◽  
Scaling And Root Planing ◽  
Pocket Depth ◽  
Probing Pocket Depth ◽  
Root Planing ◽  
Before And After ◽  
Laser Group

Introduction: The motive of the present study is to comparatively measure the competence and effectiveness of diode laser and chlorhexidine chip as adjuncts to the scaling and root planing procedure, in patients with chronic periodontitis. Aim: To evaluate the efficacy of diode laser and chlorhexidine chip before and after scaling and root planing in the management of chronic periodontitis. The objective is to compare the efficacy of chlorhexidine chip and diode laser before and after scaling and root planning on clinical parameters. Study and design: Randomized clinical trial with split mouth design done in the Department of Periodontics and Implantology. Materials and methods: Twenty chronic periodontitis patients having a probing pocket depth of 5mm-7mm on at least one interproximal site in each quadrant of the mouth were selected in the study. After initial treatment, four sites in each patient were randomly subjected to scaling and root planing (control), chlorhexidine chip application (CHX chip group), diode laser (810 nm) decontamination (Diode laser group) or combination of both (Diode laser and chip group). All subjects received a clinical periodontal examination by single examiner who recorded all the variables by manual procedure. Clinical parameters namely Plaque index (PI), Gingival Index (GI), probing pocket depth (PPD) and clinical attachment level (CAL) were assessed at baseline, one month and three months. Results were statistically analysed using one-way ANOVA followed by Post Hoc Analysis. Results: The differences in PPD reduction and CAL gain between control group and CHX chip and combination groups were statistically significant (p<0.05) at three months, whereas, the diode laser group did not show any significant difference from the control group. Conclusion: Within the limitations in the present study, the following conclusions were derived, i.e., chlorhexidine local delivery alone or in combination with diode laser decontamination is effective in improving oral hygiene, reducing gingival inflammation, reducing probing pocket depth and improving clinical attachment levels when used as adjuncts to scaling and root planing in non-surgical periodontal therapy of patients with chronic periodontitis. Keywords: Diode laser decontamination, Local drug delivery, Scaling and root planing.

TOPICAL CHEMOTHERAPEUTIC ADJUNCTS IN NON-SURGICAL PERIODONTAL THERAPY – A RANDOMISED CONTROLLED DOUBLE BLINDED TRIAL.

2021 ◽  
Vol 5 (3) ◽  
Author(s):  
Upendra Prasad ◽  
Abhinav Deshpande ◽  
Praneeta Kamble ◽  
Abhishek Singh ◽  
Adiya Apon ◽  
...  
Keyword(s):  
Chronic Periodontitis ◽  
Comparable Efficacy ◽  
Control Group ◽  
Scaling And Root Planing ◽  
Pocket Depth ◽  
Root Planing ◽  
Intergroup Comparison ◽  
Significant Difference ◽  
Group A ◽  
Chlorhexidine Gel

Introduction: Topical chemotherapeutic agents used in treatment of chronic periodontitis are antimicrobial agents which help in plaque control. The present study evaluates the efficacy of ornidazole gel with gold standard chlorhexidine gel when used as adjunct to scaling and root planing. Material and Methods: 90 patients diagnosed as chronic periodontitis, having pocket depth ?3 mm and in good systemic health were selected by systematic sampling method and divided in 3 groups. In all 3 groups scaling and root planing was done. In group A, Ornidazole gel application was done while in Group B Chlorhexidine gel application was done while Group C was control group. Plaque Index (PI) and Gingival Index (GI) were recorded at baseline, 1 and 3 months while Probing pocket depth (PPD) and Clinical attachment level (CAL) were recorded at baseline and 3 months. Results: PI and GI showed significant reduction in all three groups after 1 and 3 months compared to baseline. On inter group comparison, both PI and GI showed no significant difference in reduction of scores after 1 month and 3 months (p>0.05). PPD and CAL values showed statistically significant reduction after 3 months when compared to baseline values. The intergroup comparison revealed statistically significant reduction in group A and B compared to control group C (p<0.05). Conclusion: Ornidazole showed comparable efficacy as Chlorhexidine when used as adjunct to scaling and root planing for treatment of chronic periodontitis.

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