scholarly journals A Child with Glioblastoma Multiforme — Case Report

2020 ◽  
Vol 9 (4) ◽  
pp. 152-159
Author(s):  
Anna Rozensztrauch ◽  
◽  
Aleksandra Kołtuniuk ◽  
Keyword(s):  
Case Report ◽  
Glioblastoma Multiforme ◽  
High Grade Glioma ◽  
High Grade ◽  
Social Sphere ◽  
Nurse Caring ◽  
Care Problems ◽  
Cns Malignancy ◽  
Adjacent Brain

Introduction. Glioblastoma multiforme (GBM) is the most common central nervous system (CNS) malignancy. It is characterized by an aggressive course with the presence of rapidly growing cells, infiltrating the adjacent brain tissues. Case Report. The case report concerns a 16-year-old child with glioblastoma multiforme. The paper presents selected care problems observed in the child. Discussion. In caring for a child diagnosed with high-grade glioma, the most important care problems are severe, recurrent headaches, nausea and vomiting due to chemotherapy, chronic stress and anxiety, as well as a significant decrease in mood, resulting in e.g. social isolation. A nurse caring for a child with glioblastoma should not only focus on activities directly related to medical care, but also provide psychological support, which certainly improves the quality of life of the child and his family. Conclusions. A patient with high-grade glioma has many different types of care problems. Some are problems related to the physical sphere, others concern the psychological and social sphere. (JNNN 2020;9(4):152–159) Key Words: care, child, glioblastoma multiforme

scholarly journals High Grade tumor vs stroke. Utility of PET and MRI corregistration

ANALES RANM ◽  
2021 ◽  
Vol 138 (138(02)) ◽  
pp. 176-179
Author(s):  
M.N. Cabrera-Martín ◽  
P. Romero Fernández ◽  
M.K. Meneses Navas ◽  
P. Pérez-Segura ◽  
M. Yus Fuertes ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
High Grade Glioma ◽  
Whole Body ◽  
High Grade ◽  
Mr Images ◽  
Fdg Uptake ◽  
Area Of Interest ◽  
Pet Ct ◽  
Adjacent Brain

Sometimes, the clinical presentation of a brain tumour mimics that of stroke or viceversa. In these cases it is useful to evaluate follow-up with MR. The coregistration of PET and MR images improves the diagnostic performance of both techniques. In the area of interest, FDG uptake of any degree, with reference to the adjacent brain tissue uptake, should be considered suggestive of tumor if it corresponds to brain injury in MR, even when the FDG uptake is equal to or lower than that of the normal cerebral cortex. We present a case in which coregistration of images from both techniques contributed to the differential diagnosis of stroke and high-grade glioma, whole-body PET/CT ruled out metastatic etiology, and the results led to surgery.

scholarly journals Brain atlas for assessing the impact of tumor location on perioperative quality of life in patients with high-grade glioma: A prospective population-based cohort study

2019 ◽  
Vol 21 ◽  
pp. 101658 ◽  
Author(s):  
Lisa Millgård Sagberg ◽  
Daniel Høyer Iversen ◽  
Even Hovig Fyllingen ◽  
Asgeir Store Jakola ◽  
Ingerid Reinertsen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cohort Study ◽  
High Grade Glioma ◽  
Tumor Location ◽  
Population Based ◽  
Brain Atlas ◽  
High Grade ◽  
The Impact

Coping with a newly diagnosed high-grade glioma: patient-caregiver dyad effects on quality of life

2016 ◽  
Vol 129 (1) ◽  
pp. 155-164 ◽  
Author(s):  
K. Baumstarck ◽  
T. Leroy ◽  
Z. Hamidou ◽  
E. Tabouret ◽  
P. Farina ◽  
...  
Keyword(s):  
Quality Of Life ◽  
High Grade Glioma ◽  
High Grade ◽  
Newly Diagnosed ◽  
Glioma Patient

scholarly journals Health-related quality of life and distress in elderly vs. younger patients with high-grade glioma—results of a multicenter study

2020 ◽  
Vol 28 (11) ◽  
pp. 5165-5175 ◽  
Author(s):  
Mirjam Renovanz ◽  
Anne-Katrin Hickmann ◽  
Minou Nadji-Ohl ◽  
Naureen Keric ◽  
Elke Weimann ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Elderly Patients ◽  
High Grade Glioma ◽  
High Grade ◽  
Health Related Quality ◽  
Younger Patients ◽  
Patient Reported ◽  
Related Quality ◽  
Health Related

Abstract Objective Half of all newly diagnosed patients with glioblastoma are > 65 years still with a poor prognosis. Preserving quality of life is of high importance. However, patient reported outcome (PRO) data in this patient group is rare. The aim was to compare health-related quality of life (HRQoL) and distress between elderly and younger patients with high-grade glioma (HGG). Methods We used baseline data of a prospective study where HGG patients were enrolled from 4 hospitals. Distress was measured using the distress thermometer (DT), HRQoL using the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Core Questionnaire (QLQ-C30) plus brain module (BN20). We compared distress and HRQoL by age (≥ 65 vs. < 65 years), gender, performance score, and time since diagnosis using multivariate linear and logistic regressions. Results A total of n = 93 (30%) out of n = 309 patients were ≥ 65 years (mean 70 years, range 65–86 years). Mean DT score of elderly patients (5.2, SD 2.6) was comparable with younger patients (4.9, SD 2.6). Elderly patients reported significantly lower global health (GHS, mean elderly vs. younger; 50.8 vs. 60.5, p = 0.003), worse physical (56.8 vs. 73.3, p < 0.001) and lower cognitive functioning (51.1 vs. 63.2, p = 0.002), worse fatigue (52.5 vs. 43.5, p = 0.042), and worse motor dysfunction (34.9 vs. 23.6, p = 0.030). KPS and not age was consistently associated with HRQoL. Conclusion Physical functioning was significantly reduced in the elderly compared with younger HGG patients, and at the same time, emotional functioning and DT scores were comparable. KPS shows a greater association with HRQoL than with calendric age in HGG patients reflecting the particular importance for adequate assessment of HRQoL and general condition in elderly patients.

Neurobehavioral Status and Health-Related Quality of Life in Newly Diagnosed High-Grade Glioma Patients

2001 ◽  
Vol 19 (20) ◽  
pp. 4037-4047 ◽  
Author(s):  
Martin Klein ◽  
Martin J.B . Taphoorn ◽  
Jan J. Heimans ◽  
Henk M. van der Ploeg ◽  
W. Peter Vandertop ◽  
...  
Keyword(s):  
High Grade Glioma ◽  
Extent Of Resection ◽  
High Grade ◽  
Healthy Controls ◽  
Newly Diagnosed ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Nsclc Patients

PURPOSE: To evaluate the health-related quality of life (HRQOL) and cognitive functioning of high-grade glioma patients in the postneurosurgical period. PATIENTS AND METHODS: The HRQOL, as assessed by the Short-Form Health Survey-36, tumor-specific symptoms, and objective and subjective neuropsychologic functioning, of 68 newly diagnosed glioma patients were compared with that of 50 patients with non–small-cell lung cancer (NSCLC) and to age- and sex-matched healthy controls. The association between tumor lateralization, extent of resection, and use of medication, and the HRQOL outcomes was also investigated. RESULTS: The HRQOL of the two patient groups was similar but significantly lower than that of the healthy controls. Glioma patients reported significantly more neurologic symptoms and poorer objective and subjective neuropsychologic functioning than the NSCLC patients. Using healthy controls as the reference group, cognitive impairment assessed at the individual patient level was observed in all glioma patients and 52% of the NSCLC patients. Poor performance on timed tasks in the glioma group could be attributed, in large part, to visual and motor deficits. Tumor lateralization was found to affect neuropsychologic functioning in a predictable manner. The extent of resection was not related significantly to neuropsychologic functioning. Corticosteroid use was associated with better recognition memory, whereas antiepileptic drug use was correlated negatively with working memory capacity. CONCLUSION: The general HRQOL of glioma patients is similar to that of patients with NSCLC. However, they suffer from a number of condition-specific neurologic and neuropsychologic problems that have a significant impact on their daily lives in the postsurgical period, before treatment with radiotherapy.

scholarly journals Palliative Care in High-Grade Glioma: A Review

2020 ◽  
Vol 10 (10) ◽  
pp. 723
Author(s):  
Rita C. Crooms ◽  
Nathan E. Goldstein ◽  
Eli L. Diamond ◽  
Barbara G. Vickrey
Keyword(s):  
Quality Of Life ◽  
Palliative Care ◽  
End Of Life ◽  
Care Delivery ◽  
High Grade Glioma ◽  
Functional Independence ◽  
High Grade ◽  
Care Needs ◽  
Palliative Care Needs

High-grade glioma (HGG) is characterized by debilitating neurologic symptoms and poor prognosis. Some of the suffering this disease engenders may be ameliorated through palliative care, which improves quality of life for seriously ill patients by optimizing symptom management and psychosocial support, which can be delivered concurrently with cancer-directed treatments. In this article, we review palliative care needs associated with HGG and identify opportunities for primary and specialty palliative care interventions. Patients with HGG and their caregivers experience high levels of distress due to physical, emotional, and cognitive symptoms that negatively impact quality of life and functional independence, all in the context of limited life expectancy. However, patients typically have limited contact with specialty palliative care until the end of life, and there is no established model for ensuring their palliative care needs are met throughout the disease course. We identify low rates of advance care planning, misconceptions about palliative care being synonymous with end-of-life care, and the unique neurologic needs of this patient population as some of the potential barriers to increased palliative interventions. Further research is needed to define the optimal roles of neuro-oncologists and palliative care specialists in the management of this illness and to establish appropriate timing and models for palliative care delivery.

Predictors of distress and poorer quality of life in High Grade Glioma patients

2015 ◽  
Vol 98 (4) ◽  
pp. 525-532 ◽  
Author(s):  
Georgia K.B. Halkett ◽  
Elizabeth A. Lobb ◽  
Michelle M. Rogers ◽  
Thérèse Shaw ◽  
Anne P. Long ◽  
...  
Keyword(s):  
Quality Of Life ◽  
High Grade Glioma ◽  
High Grade

scholarly journals P17.74 * MONOFOCAL LESION OF DEMYELINATING DISEASE AND DIFFERENTIAL DIAGNOSIS WITH HIGH GRADE GLIOMA - CASE REPORT

2014 ◽  
Vol 16 (suppl 2) ◽  
pp. ii105-ii105
Author(s):  
F. Romeo ◽  
G. Maddalena ◽  
V. Conserva ◽  
V. Fumai ◽  
L. Fiorentino ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Demyelinating Disease ◽  
High Grade Glioma ◽  
High Grade ◽  
Glioma Case
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