scholarly journals Coordination through inhibition: control of stabilizing and updating circuits in spatial orientation working memory

eNeuro ◽  
2021 ◽  
pp. ENEURO.0537-20.2021
Author(s):  
Rui Han ◽  
Hsuan-Pei Huang ◽  
Chia-Lung Chuang ◽  
Hung-Hsiu Yen ◽  
Wei-Tse Kao ◽  
...  
Keyword(s):  
Working Memory ◽  
Spatial Orientation ◽  
Inhibition Control

Self-Corrected Reaching in a Three-Location Delayed-Response Search Task

1998 ◽  
Vol 9 (1) ◽  
pp. 66-70 ◽  
Author(s):  
J. Steven Reznick ◽  
J. J. Fueser ◽  
Michelle Bosquet
Keyword(s):  
Working Memory ◽  
Spatial Orientation ◽  
Search Task ◽  
Chance Level ◽  
Delayed Response ◽  
Age Group ◽  
Cause Of Error ◽  
Better Than

Infants watched an experimenter hide a toy in one of three wells and then attempted to retrieve it after a brief delay. Seven-month-olds performed at chance. Nine-month-olds reached correctly on 43% of trials, which is significantly better than chance. After an incorrect reach, infants were allowed to choose between the two remaining locations. Seven-month-olds responded at a chance level on their second reach, but 9-month-olds chose correctly more often than would be expected by chance despite a 10- to 20-s delay between hiding and search. One cause of error on the initial reach was a profound bias toward the center well. In Experiment 2, the wells were covered simultaneously, and the infant's spatial orientation was disrupted during the delay; this procedure eliminated the centripetal bias. Nine-month-olds still responded correctly more often than would be expected by chance on their second reach. These findings suggest that 9-month-olds sometimes have a more durable working memory for location than is generally reported for that age group.

scholarly journals The effect of miR-101 on the memory of rats with a model of Alzheimer’s disease

2020 ◽  
Vol 11 (3) ◽  
pp. 354-359
Author(s):  
O. G. Berchenko ◽  
N. O. Levicheva ◽  
D. O. Bevzyuk ◽  
V. V. Sokolik
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Working Memory ◽  
Spatial Memory ◽  
Spatial Orientation ◽  
Emotional Memory ◽  
Amyloid Peptide ◽  
Adaptive Behaviour ◽  
Research Activity ◽  
Model Of Alzheimer’S Disease

Memory impairment is a hallmark of Alzheimer’s disease. The clinical diagnosis of the disease is made in the later stages of its development, when specific therapy of the disease is not always effective. Therefore, the detection of early behavioral manifestations of memory disorders in the development of the disease will allow the use of preventive therapy aimed at stopping the death of neurons in brain structures. A neuroethological study of working, spatial, and emotional memory was performed in rats 15–16 months of age with a model of early manifestations of Alzheimer’s disease induced by stereotactic administration of β-amyloid peptide 40 aggregates into the hippocampus. Changes in the neuroethological components of working and spatial memory have been identified. Testing of working memory showed a violation in rats of recognizing the shape of identical objects, reducing experimental activity to unfamiliar objects and their differentiation. Spatial orientation disorders have been identified in the Barnes labyrinth. Emotional memory research has shown the preservation of innate forms of protective adaptive behaviour. At the same time, vegetative indicators reflected an increase in emotional tension. Intranasal administration of liposomal miRNA miR-101 involved in liposomes to rats with a model of early manifestations of Alzheimer’s disease improved neuroethological parameters of working and spatial memory. Restoration of the level of research activity and differentiation of familiar and unfamiliar objects in the testing of working memory in rats has been established. Spatial memory in Barnes labyrinth testing was improved by reproducing spatial orientation skills and relieving emotional stress. Thus, the intranasal use of miR-101 in Alzheimer’s disease is a promising approach to prevent the development of amyloidosis and preserve memory in the early manifestations of Alz-heimer’s disease.

Haptic spatial orientation processing and working memory

2006 ◽  
Vol 7 (S1) ◽  
pp. 181-181 ◽  
Author(s):  
Albert Postma ◽  
Sander Zuidhoek ◽  
Astrid M. L. Kappers ◽  
Matthijs L. Noordzij
Keyword(s):  
Working Memory ◽  
Spatial Orientation

scholarly journals Relationship between spatial ability, visuospatial working memory and self-assessed spatial orientation ability: a study in older adults

2015 ◽  
Vol 16 (2) ◽  
pp. 165-176 ◽  
Author(s):  
Micaela Mitolo ◽  
Simona Gardini ◽  
Paolo Caffarra ◽  
Lucia Ronconi ◽  
Annalena Venneri ◽  
...  
Keyword(s):  
Older Adults ◽  
Working Memory ◽  
Spatial Ability ◽  
Spatial Orientation ◽  
Visuospatial Working Memory ◽  
Orientation Ability

Patients with Parkinson’s Disease Show Alteration in their Visuospatial Abilities and in their Egocentric and Allocentric Spatial Orientation Measured by Card Placing Tests

2020 ◽  
Vol 10 (4) ◽  
pp. 1807-1816
Author(s):  
Cristina Fernandez-Baizan ◽  
M. Paula Fernandez Garcia ◽  
Elena Diaz-Caceres ◽  
Manuel Menendez-Gonzalez ◽  
Jorge L. Arias ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Working Memory ◽  
Parkinson's Disease ◽  
Spatial Orientation ◽  
Visuospatial Working Memory ◽  
Dominant Group ◽  
Visuospatial Abilities ◽  
Visuospatial Skills ◽  
Visuospatial Functions ◽  
Do So

Background: Visuospatial skills are impaired in Parkinson’s disease (PD). Other related skills exist, such as spatial orientation have been poorly studied. The egocentric (based on internal cues) and allocentric frameworks (based on external cues) are used in daily spatial orientation. Depending on PD onset, the allocentric framework may have a higher level of impairment in tremor-dominant and the egocentric one in akinetic-rigid. Objective: To evaluate spatial orientation and visuospatial functions in PD patients and controls, and to assess whether their performance is related to disease duration and the PD subtype (tremor-dominant and akinetic-rigid). Methods: We evaluated egocentric and allocentric spatial orientation (Egocentric and Allocentric Spatial Memory Tasks) and visuospatial abilities, span and working memory in 59 PD patients and 51 healthy controls. Results: Visuospatial skills, visuospatial span, and egocentric and allocentric orientation are affected in PD. Visuospatial skills and allocentric orientation undergo deterioration during the first 5 years of the disease progression, while egocentric orientation and visuospatial span do so at later stages (9–11 years). The akinetic-rigid subtype presents worse results in all the spatial abilities that were measured when compared to controls, and worse scores in visuospatial working memory, visuospatial abilities and allocentric orientation when compared to the tremor-dominant group. The tremor-dominant group performed worse than controls in egocentric and allocentric orientation. Conclusion: PD patients show deficits in their visuospatial abilities and in their egocentric and allocentric spatial orientation compared to controls, specifically in akinetic-rigid PD. Only spatial orientation are affected in tremor-dominant PD patients. Allocentric orientation is affected earlier in the progression of the disease.

scholarly journals Working Memory Vs Inhibitory Control: Peran terhadap Informasi Tidak Relevan sebuah Kajian Neuropsikologi

2021 ◽  
Vol 29 (1) ◽  
pp. 64
Author(s):  
Nani Restati Siregar
Keyword(s):  
Working Memory ◽  
Prefrontal Cortex ◽  
Inhibitory Control ◽  
Inhibition Control

Studi terdahulu melaporkan bahwa working memory (WM) memainkan peran penting dalam mengabaikan informasi tidak relevan sehingga hanya informasi relevan saja yang bekerja pada sistem working memory. Studi lainnya melaporkan bahwa inhibition control (IC) diperlukan untuk menghambat stimulus yang tidak relevan dan menghambat respons yang tidak dihendaki. WM dan IC adalah dua konstrak kognitif yang berbeda dan keduanya memberikan respons pada informasi tidak relevan. Namun, bagaimanakah dinamika kedua konstrak tersebut merespons informasi tidak relevan? Studi literatur kali ini bermaksud untuk menguraikan: (a) konsep mengenai working memory (WM) dan inhibitory control (IC); (b) mekanisme neural pada informasi yang tidak relevan; (c) mekanisme neural working memory dan inhibitory control pada informasi yang tidak relevan. Studi literatur ini menyimpulkan bahwa kapasitas working memory dan inhibitory control merupakan mekanisme kontrol kognitif terhadap informasi tidak relevan. Prefrontal cortex pada otak teraktivasi ketika working memory dan inhibitory control merespons informasi tidak relevan. Namun, working memory hanya menandai atau mengabaikan informasi tidak relevan sementara inhibitory control menghambat informasi tidak relevan. Inhibitory control memperkuat dan meningkatkan kinerja working memory ketika informasi tidak relevan tidak hanya cukup untuk diabaikan saja.

scholarly journals INHIBITION CONTROL AND WORKING MEMORY CAPACITY IN CHILDREN WITH SLI

PSYCHOLOGIA ◽  
2007 ◽  
Vol 50 (2) ◽  
pp. 110-121 ◽  
Author(s):  
Klara MARTON ◽  
Lyudmyla KELMENSON ◽  
Milana PINKHASOVA
Keyword(s):  
Working Memory ◽  
Working Memory Capacity ◽  
Memory Capacity ◽  
Inhibition Control
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