A study to comparison of characterizations of Zinc Oxide Eugenol based and Mineral Trioxide Aggregate based root canal sealers

Utilisation of root canal sealers to perform obturation procedures is an endorsed method in endodontics and has an indispensable role in the success of treatment. The objective of this study was to explore the pediatric dentists’ preference for root canal sealers for obturating permanent teeth. 360 permanent teeth with gutta-percha obturation done by pediatric dentists were analyzed for the study. The variety of root canal sealers that are utilised for obturating the permanent teeth by pediatric dentists were assessed. The data were obtained from a patient management software. Chi-square test was performed. Out of the 360 permanent teeth, 186 teeth were obturated using resin-based sealers, 101 teeth using zinc oxide eugenol-based sealers and 73 teeth were obturated using calcium hydroxide-based sealers, with statistically significant difference between the three materials (P<0.05). Based on the findings of the present study, resin sealers followed by zinc oxide eugenol sealers and calcium hydroxide sealers were more preferred by pediatric dentists for root canal therapy in permanent teeth.

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Influence of the powder/liquid ratio on the properties of zinc oxide?eugenol-based root canal sealers

Dental Materials ◽

10.1016/j.dental.2004.02.002 ◽

2004 ◽

Vol 20 (10) ◽

pp. 915-923 ◽

Cited By ~ 19

Author(s):

J CAMPS

Keyword(s):

Zinc Oxide ◽

Root Canal ◽

Liquid Ratio ◽

Zinc Oxide Eugenol ◽

Root Canal Sealers

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Root canal sealers in dental practice

International Journal of Research in Pharmaceutical Sciences ◽

10.26452/ijrps.v11ispl3.2892 ◽

2020 ◽

Vol 11 (SPL3) ◽

pp. 68-71

Author(s):

Vinaya Swetha T ◽

Dhanraj Ganapathy ◽

Kiran Kumar

Keyword(s):

Zinc Oxide ◽

Root Canal ◽

Endodontic Treatment ◽

Questionnaire Study ◽

Dental Practice ◽

Online Forum ◽

Private Practitioners ◽

Zinc Oxide Eugenol ◽

Knowledge And Attitude ◽

Root Canal Sealers

Root canal sealers are important materials commonly used in endodontic treatment. Endodontic treatment for cleaning the root canal and removing the pulp and filling with manmade materials. The aim of the study was to assess the knowledge and attitude of the practitioners regarding root canal sealers in endodontic treatment. It is an online-based questionnaire study in which ten questions were circulated through an online forum through google forms and results were analysed using SPSS. In this study, it was observed that private practitioners most commonly use zinc oxide eugenol based sealers (50%), but it shows that methacrylate resin-based sealers (50%) are most effective in sealing. It shows that private practitioners are more aware of root canal sealers and its uses, and about its properties.

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Induction of cyclooxygenase-2 mRNA and protein expression by epoxy resin and zinc oxide-eugenol based root canal sealers in human osteoblastic cells

Biomaterials ◽

10.1016/s0142-9612(02)00584-7 ◽

2003 ◽

Vol 24 (11) ◽

pp. 1869-1875 ◽

Cited By ~ 26

Author(s):

Fu-Mei Huang ◽

Ming-Yung Chou ◽

Yu-Chao Chang

Keyword(s):

Zinc Oxide ◽

Protein Expression ◽

Epoxy Resin ◽

Root Canal ◽

Cyclooxygenase 2 ◽

Osteoblastic Cells ◽

Zinc Oxide Eugenol ◽

Mrna And Protein Expression ◽

Human Osteoblastic Cells ◽

Root Canal Sealers

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The evaluation of cytotoxicity and cytokine IL-6 production of root canal sealers with and without the incorporation of simvastatin: an invitro study

BMC Oral Health ◽

10.1186/s12903-022-02039-y ◽

2022 ◽

Vol 22 (1) ◽

Author(s):

Apoorva Sharma ◽

Kavitha Sanjeev ◽

Vinola M. J. Selvanathan ◽

Mahalaxmi Sekar ◽

Nikhil Harikrishnan

Keyword(s):

Zinc Oxide ◽

Root Canal ◽

Inflammatory Marker ◽

Pairwise Comparison ◽

Mouse Fibroblast ◽

L929 Cells ◽

Inflammatory Reactions ◽

Zinc Oxide Eugenol ◽

Time Periods ◽

Root Canal Sealers

Abstract Background Freshly mixed root canal sealers when proximate the periapical tissues, trigger varying degrees of cytotoxicity/inflammatory reactions. Simvastatin, a class of the drug statin, is a widely used cholesterol-lowering agent with additional anti-inflammatory activities. This study assessed the effects of simvastatin on cytotoxicity and the release of IL-6 (Interleukin-6) production when incorporated in zinc oxide eugenol and methacrylate resin-based sealers. Methods Experimental groups consisted of conventional zinc oxide eugenol and methacrylate based-EndoREZ sealers (ZE & ER respectively) and 0.5 mg/mL simvastatin incorporated sealers (ZES & ERS). L929 mouse fibroblast cells were exposed to freshly mixed experimental sealers and evaluated for cytotoxicity (MTT assay) and inflammation levels (inflammatory marker IL-6 for ELISA) at various time intervals (0h, 24h and 7th day). The values were compared to the cell control (CC; L929 cells alone) and solvent control (SC; L929 cells + DMSO) groups. All the experiments were conducted in triplicates and subjected to statistical analysis using IBM SPSS Statistics software. Non parametric tests were conducted using Kruskal-Wallis and Friedman tests for inter-group and intra-group comparisons respectively. Pairwise comparison was conducted by post hoc Dunn test followed by Bonferroni correction. P values < 0.05 were considered statistically significant. Results All the experimental groups (ZE, ER, ZES, ERS) exhibited varying degree of cytotoxicity and IL-6 expression compared to the control groups CC and SC. The cell viability for ZE and ER decreased on day 7 as compared to 24 h. ZES and ERS had higher viable cells (75.93% & 79.90%) compared to ZE and ER (54.39% & 57.84%) at all time periods. Increased expression of IL-6 was observed in ZE & ER (25.49 pg/mL & 23.14 pg/mL) when compared to simvastatin incorporated ZE & ER (ZES-12.70 pg/mL & ERS-14.68 pg/mL) at all time periods. Highest level of cytotoxicity and inflammation was observed in ZE compared to all the other groups on day 7. Conclusions Addition of 0.5 mg/mL of simvastatin to the sealers (ZES and ERS) decreased the cytotoxicity in the freshly mixed state and reduces their inflammatory effect.

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