CONCENTRATIONS AND FATTY ACID COMPOSITION OF SERUM LIPIDS FOLLOWING SERIOUS COMPLICATING ILLNESS IN HYPOTHYROIDISM

1972 ◽  
Vol 71 (1) ◽  
pp. 80-85 ◽  
Author(s):  
Knut Kirkeby
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Linoleic Acid ◽  
Acid Composition ◽  
Serum Cholesterol ◽  
Serum Lipids ◽  
Acute Illness ◽  
Unknown Factor ◽  
Hypothyroid Patients ◽  
Made In

ABSTRACT Studies on serum lipids and their fatty acid composition have been carried out in 3 patients with untreated hypothyroidism, who also suffered from acute complicating diseases. It was found that the hypothyroid patients reacted to the acute complicating disease in the same way as euthyroid subjects, i. e. with a lowering of serum cholesterol and phospholipids, and disturbances in fatty acid composition. Very low values of linoleic acid percentages were found following one week of complicating disease, contrary to findings made in hypothyroid patients without any complicating diseases. The changes in fatty acid composition indicate a very active re-synthesis of lipoproteins. It is suggested that the unknown factor responsible for lipoprotein degradation in acute illness also activates their re-synthesis, since the formation and turnover of lipoproteins in hypothyroidism are usually low.

FATTY ACID COMPOSITION OF SERUM LIPIDS FOLLOWING A SINGLE INTAKE OF THYROXINE

1972 ◽  
Vol 71 (1) ◽  
pp. 73-79 ◽  
Author(s):  
Knut Kirkeby
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Linoleic Acid ◽  
Acid Composition ◽  
Serum Lipids ◽  
Oral Intake ◽  
Eicosatrienoic Acid ◽  
Acid Deficiency ◽  
Observation Period ◽  
Made In

ABSTRACT Studies of serum lipids and of the fatty acid composition of the main fractions were performed in a 17-year-old girl following a large single oral intake of 1-thyroxine. Cholesterol and phospholipids values decreased markedly. These changes were followed by pronounced disturbances in the fatty acid composition of these fractions, with a lowering of linoleic acid, and an increase in arachidonic acid percentages. Other changes were increased oleic acid in the cholesterol esters, and increased eicosatrienoic acid in the phospholipids. The changes were in accordance with findings made in patients with long standing thyrotoxicosis. They support the hypothesis that increased synthesis of arachidonic from linoleic acid contributes to the linoleic acid deficiency seen in thyrotoxicosis. The serum lipids and values for fatty acid composition showed a tendency to return to the original levels within 10 to 15 days. However, in the phospholipids some of the very long-chained fatty acids decreased during the 40-day observation period.

FATTY ACID COMPOSITION OF SERUM LIPIDS IN HYPER- AND HYPOTHYROIDISM

1972 ◽  
Vol 71 (1) ◽  
pp. 62-72 ◽  
Author(s):  
Knut Kirkeby
Keyword(s):  
Fatty Acids ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Linoleic Acid ◽  
Acid Composition ◽  
Serum Lipids ◽  
Unsaturated Fatty Acids ◽  
Eicosatrienoic Acid ◽  
High Linoleic Acid ◽  
Absolute Concentrations

ABSTRACT The fatty acid composition of cholesterol esters, phospholipids, and triglycerides of the serum has been studied in groups of hyperthyroid and hypothyroid women and also in control material matched for age. In hyperthyroidism, a decrease in the proportions of linoleic acid and an increase in the proportions of some saturated and mono-unsaturated fatty acids were observed. When absolute concentrations were considered, it appeared that the decrease in linoleic acid was almost equivalent to the entire decrease in total fatty acids in the serum of the hyperthyroid patients. In hypothyroidism no changes were noted in the proportions of linoleic, saturated and mono-unsaturated fatty acids, and the absolute concentrations reflected the general increase in serum lipids. It is believed that these findings may be explained by the changes in lipid turnover which are known to occur in disturbances of thyroid function. In hyperthyroidism, they lead to a linoleic acid deficiency, while a sparing effect must be operating in hypothyroidism. The finding of relatively high linoleic acid values combined with hyperlipaemia in hypothyroidism seems to be characteristic of the condition, since other types of hyperlipaemia are almost invariably combined with low percentages of linoleic acid. Results regarding arachidonic and eicosatrienoic acid are consistent with increased synthesis in hyperthyroidism, and decreased synthesis in hypothyroidism.

Effect of soybean leci-vita product on serum lipids and fatty acid composition in patients with elevated serum cholesterol and triglyceride levels

2003 ◽  
Vol 23 (4) ◽  
pp. 465-477 ◽  
Author(s):  
Danijela Ristić Medić ◽  
Vanja Ristić ◽  
Vesna Tepšić ◽  
Marija Ranić ◽  
Gordana Ristić ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Serum Cholesterol ◽  
Serum Lipids ◽  
Elevated Serum ◽  
Elevated Serum Cholesterol

The effect of SNP (rs174537) in FADS1 gene on fatty acid composition in serum lipids

2020 ◽  
Author(s):  
Tereza Metelcová ◽  
Markéta Vaňková ◽  
Hana Zamrazilová ◽  
Milena Hovhannisyan ◽  
Eva Tvrzická ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Serum Lipids

The risk to develop NIDDM is related to the fatty acid composition of the serum cholesterol esters

Diabetes ◽  
1994 ◽  
Vol 43 (11) ◽  
pp. 1353-1357 ◽  
Author(s):  
B. Vessby ◽  
A. Aro ◽  
E. Skarfors ◽  
L. Berglund ◽  
I. Salminen ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Serum Cholesterol ◽  
Cholesterol Esters

FEATURES OF THE OIL-BEARING-CROP (CHARTHAMUS) CULTIVATION UNDER THE CONTRASTIVE EDAPHIC-CLIMATIC CONDITIONS

2018 ◽  
pp. 31-37
Author(s):  
S. К. Temirbekova ◽  
Yu. V. Afanaseva ◽  
I. M. Kulikov ◽  
G. V. Metlina ◽  
S. A. Vasilchenko
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Linoleic Acid ◽  
Acid Composition ◽  
Oil Content ◽  
Moscow Region ◽  
Average Weight ◽  
North Caucasus ◽  
Saratov Region ◽  
Rostov Region

The results of long-term studies of the biological, morphological and phenological features of the introduced new culture of safflower in the Central, Volga and North Caucasus regions are presented. Optimum parameters of depth of seeding (5-6 cm), seeding rates (300-350 thousand pieces/hectare or 12-14 kg), ensuring high productivity, oil content and quality of seeds are established. For the first time, the relationship between moisture availability of vegetation periods with accumulation of oil content and a change in the fatty acid composition was established. Oilseed (in untreated seeds) in the regions was from 14,5 to 31,2%, in excessively wet 2013 – 6,4% in the Moscow region and 8,6% in the Saratov region. Fatty acid composition revealed a high content of oleic acid in Krasa Stupinskaya variety – 13,6-16,8%, linoleic acid – 68,5-75,7%. The yield of oil in the Moscow region was 240 kg/ha. The yield of Krasa Stupinskaya in the Moscow Region was 0,6 t/ha, the Rostov Region 0,8 t/ha and Saratov Region 1,2 t/ha, with an average weight of 1000 seeds, respectively, by regions: 40,0 g, 47,3 g and 40,9 g. The growing season for growing seeds was 105 days in the Moscow Region, 94 days in the Rostov Region and 95 days in the Saratov Region. It has been established that excessive moistening during the flowering and seed filling period increases the harmfulness of enzyme-mycosis seed depletion (EMIS) – biological injury during maturation (enzymatic stage), followed by the seeding of the seeds with the phytopathogen Alternaria carthami Chowdhury. In the breeding programs for productivity and oil content, it is recommended to use the varieties Moldir (Kazakhstan) and Krasa Stupinskaya (FGBNU VSTISP), the fatty acid composition of which is characterized by an increased content of oleic and linoleic acid, which is of particular value for storage and use for food purposes.

Effect of slaughter season on fatty acid composition, conjugated linoleic acid isomers and nutritional value of intramuscular fat in Barrosã-PDO veal

Meat Science ◽  
2007 ◽  
Vol 75 (1) ◽  
pp. 44-52 ◽  
Author(s):  
Cristina M.M. Alfaia ◽  
Matilde L.F. Castro ◽  
Susana I.V. Martins ◽  
Ana P.V. Portugal ◽  
Susana P.A. Alves ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Acid Composition ◽  
Nutritional Value ◽  
Intramuscular Fat

Effect of linseed feeding at similar linoleic acid levels on the fatty acid composition of double-muscled Belgian Blue young bulls

Meat Science ◽  
2004 ◽  
Vol 66 (2) ◽  
pp. 307-315 ◽  
Author(s):  
K. Raes ◽  
L. Haak ◽  
A. Balcaen ◽  
E. Claeys ◽  
D. Demeyer ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Linoleic Acid ◽  
Acid Composition
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