AGE RELATED CHANGES AND INTERRELATIONSHIPS BETWEEN PLASMA TESTOSTERONE, OESTRADIOL AND TESTOSTERONE-BINDING GLOBULIN IN NORMAL ADULT MALES

1973 ◽  
Vol 74 (4) ◽  
pp. 792-800 ◽  
Author(s):  
Karl M. Pirke ◽  
Peter Doerr
Keyword(s):  
Binding Capacity ◽  
Plasma Testosterone ◽  
Age Group ◽  
Adult Males ◽  
Total Plasma ◽  
Biological Meaning ◽  
Age Related ◽  
Group I ◽  
Peripheral Conversion ◽  
Age Related Changes

ABSTRACT Testosterone (T), oestradiol-17β (Oe2) and binding capacity of the testosterone-binding globulin (TeBG) were measured in plasma of 84 adult males (22–90 years). The medians for age group I (22– 61 years, n = 50) were: T 545 ng/100 ml, Oe2 1.66 ng/100 ml, TeBG capacity 1.44 μg T/100 ml; the medians for age group II (67–90 years, n = 34) were: T 459 ng/100 ml, Oe2 2.56 ng/100 ml, TeBG capacity 2.05 μg T/100 ml. The decrease of T and the increase of Oe2 and TeBG capacity with age were significant. The significant correlation (P < 0.01) for either age group between T and Oe2 may be ascribed to a simultaneous secretion and/or a peripheral conversion of T to Oe2. The significant correlation (P < 0.05) between T and TeBG for the old age group probably reflects the comparatively high percentage of total plasma T bound to TeBG. The biological meaning of the correlation between Oe2 and TeBG is discussed.

AGE RELATED CHANGES IN FREE PLASMA TESTOSTERONE, DIHYDROTESTOSTERONE AND OESTRADIOL

1975 ◽  
Vol 80 (1) ◽  
pp. 171-178 ◽  
Author(s):  
Karl M. Pirke ◽  
Peter Doerr
Keyword(s):  
Healthy Adult ◽  
Equilibrium Dialysis ◽  
Plasma Testosterone ◽  
Age Group ◽  
Adult Males ◽  
Age Related ◽  
Group I ◽  
Group Ii ◽  
Free Plasma ◽  
Age Related Changes

ABSTRACT The age related changes on free plasma testosterone (T), dihydrotestosterone (DHT) and oestradiol (Oe2) were determined in 82 healthy adult males. Forty-six subjects were between 22 and 61 years of age (group I), 36 between 67 and 93 years (group II). The percentage of free, non protein bound hormone was determined by equilibrium dialysis of undiluted plasma against isotonic phosphate buffer at 37°C. Total hormone concentrations were measured by radioimmunoassay. The percentage of free T was 2.24 % (median), 1.65–3.42 (95 percentiles) in group I and 1.65 % (1.24–2.26) in group II. The percentage of free DHT decreased from 1.17 % (0.80–2.03) in group I to 0.83% (0.52–1.55) in group II. The decrease in % free Oe2 was only very small: group I = 2.49% (2.13–2.96), ad group II = 2.31% (1.95–3.17). The fall in free T by 43.3% from 12.2 ng/100 ml (6.74–25.0) in group I to 6.90 ng/ml (3.57–10.6) in group II was twice as high as that of total T, which decreased on an average by 20.6%. Free DHT decreased by 25.8 %: group I = 578 pg/100 ml (266–987), group II = 429 pg/100 ml (168–723), while total DHT was not significantly different between the two groups (–1.9%). Free Oe2 was increased in old age: group I = 42.4 pg/100 ml (26.0–69.4), group II = 55.7 pg/100 ml (35.8–118.9). The increase in free Oe2 by 31.4% was almost as high as that of the total Oe2 (46.9%).

Age-related changes in the TRB and IGH repertoires in healthy adult males and females

2021 ◽  
Author(s):  
Mingxing Gong ◽  
Xueying Li ◽  
Anqi Zheng ◽  
Hongxu Xu ◽  
Shi Xie ◽  
...  
Keyword(s):  
Healthy Adult ◽  
Adult Males ◽  
Age Related ◽  
Males And Females ◽  
Age Related Changes

scholarly journals Analysis of zinc concentration in the saliva of individuals at different age ranges

2016 ◽  
Vol 31 (1) ◽  
pp. 12
Author(s):  
Marcela Lima Cardoso Selow ◽  
Flávia Lunelli ◽  
Iran Vieira ◽  
Mariana Doff Sotta ◽  
Wilson Denis Martins ◽  
...  
Keyword(s):  
Zinc Concentration ◽  
Zinc Supplementation ◽  
Salivary Flow ◽  
Group Iv ◽  
Oral Lesions ◽  
Age Group ◽  
Healthy Individuals ◽  
Group Iii ◽  
Age Related ◽  
Group I

Objectives: Zinc plays an important role in the homeostasis of the human body. In the oral cavity, its absence causes hypogeusia. Zinc supplementation acts improving taste acuity and oral lesions healing. However, some aspects regarding to salivary zinc contents and syalometric variables, as well as, its variations among age-related groups, are lacking. The objective of this study was to measure the zinc concentration in the saliva in different age range.Methods: One hundred and twenty healthy individuals have donated saliva and they were divided in to four groups according to age: Group I = 18-29 years old; Group II = 30-39 years old; Group III: 40-49 years old and Group IV: 50-59 years old.Results: The research revealed that there are differences between salivary parameters, salivary flow rate, buffering capacity and pH, when they are correlated with the zinc present in saliva, but the salivary zinc concentration is not age dependent.Conclusion: pH and BA had no influence in the salivary zinc concentration, but the salivary flow can interfere in the zinc concentration.

scholarly journals POSITION OF HEADS OF TEMPOROMANDIBULAR JOINT IN PATIENTS WITH MALOCCLUSION

2020 ◽  
Vol 20 (3) ◽  
pp. 64-67
Author(s):  
V.D. Kuroiedova ◽  
O.A. Stasiuk ◽  
Ye.Ye. Vyzhenko ◽  
Yu.K. Sokolohorska-Nykina
Keyword(s):  
Temporomandibular Joint ◽  
Permanent Dentition ◽  
Mixed Dentition ◽  
Correct Position ◽  
Rotational Displacement ◽  
Age Related ◽  
Group I ◽  
Number Of Patients ◽  
Left And Right ◽  
Age Related Changes

This article describes the assessment of the condition, symmetry of temporomandibular joint and timely diagnosis of its dysfunction based on to H. Gelb method in malocclusion. The objective of this study was to investigate the position and assess the symmetry of the temporomandibular joint heads according to H. Gelb in cases of malocclusion. Materials and мethods. The study was based on analysis of computed tomographs of 70 patients with malocclusion. Depending on the stage of the occlusion development, the patients were divided into two groups: I group included 30 patients with mixed dentition and II group included 40 patients with permanent dentition. Results. The results obtained demonstrated that regardless of the pathology of the occlusion and age, only 8 patients had the correct bite, i.e. the symmetrical position of the temporomandibular joint heads in the Gelb 4/7 position. The most frequent symmetric position of the articular heads in the patients of the I group I was the Gelb ¼ position found in 16 patients; the Gelb 1/5 position was revealed in 8 patients of the II group that can be explained as age-related changes in the displacement of the articular heads from the Gelb 1/4 to 1/5 position. Conclusions. According to the results of our research, it was found that regardless of the malocclusion and age, patients who have the correct position of the temporomandibular joint heads on the left and right in the Gelb 4/7 position make up only 10.52%. The age-related dynamics of the rotational displacement of the centre of the articular heads from the Gelb 1/4 to 1/5 position has been observed, and the number of patients with the asymmetric position of the temporomandibular joint articular heads is increaing.

Age Related Changes in Protein C Activity in Healthy Adult Males

1991 ◽  
Vol 65 (03) ◽  
pp. 326-327 ◽  
Author(s):  
R C Tait ◽  
Isobel D Walker ◽  
S I A Islam ◽  
R Mitchell ◽  
J A Conkie ◽  
...  
Keyword(s):  
Protein C ◽  
Healthy Adult ◽  
Adult Males ◽  
Age Related ◽  
Protein C Activity ◽  
Age Related Changes

scholarly journals Computed tomographic assessment of equine maxillary cheek teeth anatomical relationships, and paranasal sinus volumes

2017 ◽  
Vol 181 (17) ◽  
pp. 452-452 ◽  
Author(s):  
Tiziana Liuti ◽  
Richard Reardon ◽  
Paddy M Dixon
Keyword(s):  
Maxillary Sinus ◽  
Age Group ◽  
Medial Aspect ◽  
Computed Tomographic ◽  
Age Related ◽  
Infraorbital Canal ◽  
The Mean ◽  
The Individual ◽  
Gross Examination ◽  
Age Related Changes

Disorders affecting the equine maxillary cheek teeth and paranasal sinuses are relatively common, but limited objective information is available on the dimensions and relationships of these structures in horses of different ages. The aims of this study were to assess age-related changes in the positioning and anatomical relationships of the individual maxillary cheek teeth with the infraorbital canal and maxillary septum and the volumes of the individual sinus compartments. CT and gross examination were performed on 60 normal equine cadaver heads that were aged by their dentition. The intrasinus position of cheek teeth, length of reserve crowns, relationship to the infraorbital canal and measurements of rostral drift and sinus compartment volumes were assessed from CT images. The findings included that Triadan 10 alveoli lay fully or partially in the rostral maxillary sinus (RMS) in 60% of cases. The infraorbital canal lay directly on the medial aspect of the alveolar apex in younger horses. The Triadan 11’sclinical crowns and apices drifted a mean of 2.48 and 2.83 cm more rostral to the orbit, respectively, in the >15 years old vs the <6 years old age group. The mean volumes of sinus compartments ranged from 175 cm3for the caudal maxillary sinus (CMS) to 4 cm3for the ethmoidal sinus (ES). This information should be of value in the diagnosis and treatment of equine dental and sinus disorders and as reference values for further studies.

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