Maternal vitamin D depletion disrupts neonatal skeletal development in mice

2015 ◽  
Author(s):  
Harriet Buckley ◽  
Stephanie Borg ◽  
Kirsty Nicholson ◽  
Mark Kinch ◽  
David Hughes ◽  
...  
Keyword(s):  
Vitamin D ◽  
Skeletal Development ◽  
Maternal Vitamin ◽  
Vitamin D Depletion

scholarly journals Maternal vitamin D depletion alters DNA methylation at imprinted loci in multiple generations

2016 ◽  
Vol 8 (1) ◽  
Author(s):  
Jing Xue ◽  
Sarah A. Schoenrock ◽  
William Valdar ◽  
Lisa M. Tarantino ◽  
Folami Y. Ideraabdullah
Keyword(s):  
Dna Methylation ◽  
Vitamin D ◽  
Maternal Vitamin ◽  
Multiple Generations ◽  
Vitamin D Depletion

Maternal vitamin D depletion alters neurogenesis in the developing rat brain

2007 ◽  
Vol 25 (4) ◽  
pp. 227-232 ◽  
Author(s):  
Xiaoying Cui ◽  
John J. McGrath ◽  
Thomas H.J. Burne ◽  
Alan Mackay‐Sim ◽  
Darryl W. Eyles
Keyword(s):  
Vitamin D ◽  
Rat Brain ◽  
Maternal Vitamin ◽  
Developing Rat ◽  
Vitamin D Depletion

Early life vitamin D depletion and mechanical loading determine methylation changes in the RXRA, Runx2 and osterix promoters in mice

2019 ◽  
Author(s):  
Stephanie Borg ◽  
Nevena Krstic ◽  
Harriet Buckley ◽  
Elizabeth Curtis ◽  
Cyrus Cooper ◽  
...  
Keyword(s):  
Vitamin D ◽  
Mechanical Loading ◽  
Early Life ◽  
Vitamin D Depletion

Effect of Maternal Vitamin D Status on Vitamin D Levels in Early Infancy, in a Tertiary Care Centre in Sri Lanka

2019 ◽  
Author(s):  
Anusha Kaneshapillai ◽  
Usha Hettiaratchi ◽  
Dulanie Gunaseker ◽  
Shamini Rathapan ◽  
Guwani Liyanage
Keyword(s):  
Vitamin D ◽  
Sri Lanka ◽  
Tertiary Care ◽  
Early Infancy ◽  
Vitamin D Status ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Maternal Vitamin ◽  
Vitamin D Levels ◽  
Maternal Vitamin D Status

Maternal Vitamin D Status and Development of Asthma and Allergy in Early Childhood

2015 ◽  
Vol 15 (11) ◽  
pp. 900-912 ◽  
Author(s):  
Anna Papadopoulou ◽  
Evangelia Bountouvi ◽  
Vasiliki Papaevaggelou ◽  
Kostas Priftis
Keyword(s):  
Vitamin D ◽  
Early Childhood ◽  
Vitamin D Status ◽  
Maternal Vitamin ◽  
Asthma And Allergy ◽  
Maternal Vitamin D Status

scholarly journals Influence of vitamin D serum concentration, prenatal care and social determinants on birth weight: a northeastern Brazilian cohort study

2019 ◽  
Vol 122 (03) ◽  
pp. 284-292 ◽  
Author(s):  
Marcos Pereira-Santos ◽  
Gisele Queiroz Carvalho ◽  
Djanilson Barbosa dos Santos ◽  
Ana Marlucia Oliveira
Keyword(s):  
Vitamin D ◽  
Birth Weight ◽  
Prenatal Care ◽  
Serum Concentration ◽  
Pregnant Women ◽  
Social Determinants ◽  
Maternal Education ◽  
Late Onset ◽  
High Birth Weight ◽  
Maternal Vitamin

AbstractThe relationship among social determinants, vitamin D serum concentration and the health and nutrition conditions is an important issue in the healthcare of pregnant women and newborns. Thus, the present study analyses how vitamin D, prenatal monitoring and social determinants are associated with birth weight. The cohort comprised 329 pregnant women, up to 34 weeks gestational age at the time of admission, who were receiving care through the prenatal services of Family Health Units. Structural equation modelling was used in the statistical analysis. The mean birth weight was 3340 (sd 0·545) g. Each nmol increase in maternal vitamin D serum concentration was associated with an increase in birth weight of 3·06 g. Prenatal healthcare with fewer appointments (β −41·49 g, 95 % CI −79·27, −3·71) and late onset of care in the second trimester or third trimester (β −39·24 g, 95 % CI −73·31, −5·16) favoured decreased birth weight. In addition, low socio-economic class and the practice of Afro-Brazilian religions showed a direct association with high vitamin D serum concentrations and an indirect association with high birth weight, respectively. High gestational BMI (β 23·84, 95 % CI 4·37, 43·31), maternal education level (β 24·52 g, 95 % CI 1·82, 47·23) and length of gestation (β 79·71, 95 % CI 52·81; 106·6) resulted in high birth weight. In conclusion, maternal vitamin D serum concentration, social determinants and prenatal care, evaluated in the context of primary healthcare, directly determined birth weight.

scholarly journals Maternal Vitamin D and Newborn Telomere Length

Nutrients ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 2012
Author(s):  
Lisa Daneels ◽  
Dries S. Martens ◽  
Soumia Arredouani ◽  
Jaak Billen ◽  
Gudrun Koppen ◽  
...  
Keyword(s):  
Vitamin D ◽  
Cord Blood ◽  
Telomere Length ◽  
First Trimester ◽  
Maternal Serum ◽  
Adverse Outcomes ◽  
Dietary Vitamin ◽  
Maternal Vitamin ◽  
Vitamin D Intake ◽  
Diet Supplements

Nutrition is important during pregnancy for offspring health. Gestational vitamin D intake may prevent several adverse outcomes and might have an influence on offspring telomere length (TL). In this study, we want to assess the association between maternal vitamin D intake during pregnancy and newborn TL, as reflected by cord blood TL. We studied mother–child pairs enrolled in the Maternal Nutrition and Offspring’s Epigenome (MANOE) cohort, Leuven, Belgium. To calculate the dietary vitamin D intake, 108 women were asked to keep track of their diet using the seven-day estimated diet record (EDR) method. TL was assessed in 108 cord blood using a quantitative real-time PCR method. In each trimester of pregnancy, maternal serum 25-hydroxyvitamin D (25-OHD) concentration was measured. We observed a positive association (β = 0.009, p-value = 0.036) between newborn average relative TL and maternal vitamin D intake (diet + supplement) during the first trimester. In contrast, we found no association between average relative TL of the newborn and mean maternal serum 25-OHD concentrations during pregnancy. To conclude, vitamin D intake (diet + supplements), specifically during the first trimester of pregnancy, is an important factor associated with TL at birth.

scholarly journals Differential regulation of a placental SAM68 and sFLT1 gene pathway and the relevance to maternal vitamin D sufficiency

2020 ◽  
Vol 22 ◽  
pp. 196-203
Author(s):  
Oyindamola Awe ◽  
James M. Sinkway ◽  
Rebecca P. Chow ◽  
Quentell Wagener ◽  
Elizabeth V. Schulz ◽  
...  
Keyword(s):  
Vitamin D ◽  
Differential Regulation ◽  
Maternal Vitamin ◽  
Gene Pathway
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