scholarly journals Preoperative diagnosis of insulinoma: low body mass index, young age, and female gender are associated with negative imaging by endoscopic ultrasound

2007 ◽  
Vol 157 (2) ◽  
pp. 209-213 ◽  
Author(s):  
P H Kann ◽  
D Ivan ◽  
A Pfützner ◽  
Th Forst ◽  
P Langer ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Endoscopic Ultrasound ◽  
Malignant Tumors ◽  
Female Gender ◽  
Young Age ◽  
Invasive Approach ◽  
Minimal Invasive Approach ◽  
Low Body Mass Index ◽  
Negative Imaging

Objective: Endoscopic ultrasound (EUS) is a highly reliable procedure to localize insulinomas preoperatively. It has been considered to be important in planning surgical strategy, especially considering a minimal invasive approach. However, even under ideal conditions experienced examiners miss about 10–20% of insulinomas by EUS imaging. Design and methods: This retrospective study aimed to identify factors associated with negative EUS imaging. Twenty-nine consecutive patients (24 benign and 5 malignant) with sporadic pancreatic insulinomas confirmed by successful surgery and positive histopathology were included. All EUS examinations were performed by one single experienced examiner over a period of one decade. Results: Three of the tumors were not detected by preoperative EUS as they were isoechoic to the surrounding healthy pancreatic tissue; 25 could be detected as hypoechoic lesions, (including all malignant tumors), and one lesion was hyperechoic. Low body mass index (P=0.053) and young age (P=0.037) were associated with negative EUS imaging. All patients with negative imaging were females. The position on the examiner’s learning curve, the diameter and location of insulinoma, and endocrine parameters (insulin concentrations and insulin–glucose ratios in the prolonged fasting test) had no influence on the success of EUS imaging. Conclusions: Some insulinomas are missed by preoperative EUS imaging as they are completely isoechoic. A low body mass index, female gender, and young age might be risk factors for negative imaging.

The biopsychosocial assessment of people with low body mass index

2016 ◽  
Vol 20 (2) ◽  
pp. 64-71
Author(s):  
Funda Yıldırım Baş ◽  
Bahriye Arslan ◽  
Yasemin Türker
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Low Body Mass Index ◽  
Biopsychosocial Assessment

An Atypical Form of Diabetes Among Low Body Mass Index Individuals in India

2021 ◽  
Author(s):  
Eric Lontchi-Yimagou ◽  
Riddhi Dasgupta ◽  
Shajith Anoop ◽  
Sylvia Kehlenbrink ◽  
Sudha Koppaka ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Atypical Form ◽  
Low Body Mass Index

Abstract 13944: J Relationship of Body Mass Index of 22-year Cardiovascular Disease Mortality versus Body Mass Index

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
William J Kostis ◽  
Javier Cabrera ◽  
Fei Wang ◽  
Sara J Guterl ◽  
Dhammika Amaratunga ◽  
...  
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Body Mass ◽  
Systolic Hypertension ◽  
Female Gender ◽  
The Elderly ◽  
Linear Term ◽  
Quadratic Term ◽  
All Cause Mortality ◽  
Cv Disease

Introduction: J relationships of body mass index (BMI) with mortality have been described. However, little data are available on long-term follow-up in controlled clinical trials with respect to cardiovascular (CV) and all cause mortality. Hypothesis: We tested whether there is a J shape relationship between BMI with CV and all cause mortality at 22 years in the Systolic Hypertension in the Elderly Program (SHEP). Methods: SHEP was a placebo controlled, randomized clinical trial of antihypertensive therapy in patients with isolated systolic hypertension aged 60 and older. The relationship between CV and all cause mortality with baseline BMI was examined in 4,211 SHEP participants. Results: In unadjusted analyses, a J relationship was observed for all-cause mortality (linear term p=0.0318, quadratic term p=0.3217 and tricubic term p=0.0046) and for CV mortality (linear term p=0.0962, quadratic term p=0.6866 and tricubic term p=0.0908, left figure). The lowest risk was at a BMI of 25.9 for all-cause and 25.5 for CV mortality. The J shaped relationship between BMI and mortality was attenuated after adjustment for age, gender, comorbidities (e.g. diabetes, heart failure) and risk factors for CV disease (e.g. smoking and dyslipidemia, right figure). Age and gender were significant predictors of both all- cause and CV mortality: age p<0.0001, female gender p=0.0063 for all-cause mortality and p<0.0001 for age and p=0.0004 for female gender for CV mortality. <br/Conclusions: This study indicates that both very low and very high BMI are markers of high risk. The J relationship between BMI and mortality is mediated by age, female gender, comorbidities and risk factors for CV disease.

Outcomes of laparoscopic adjustable gastric banding in patients with low body mass index

2010 ◽  
Vol 6 (4) ◽  
pp. 367-371 ◽  
Author(s):  
Jenny Choi ◽  
Mary Digiorgi ◽  
Luca Milone ◽  
Beth Schrope ◽  
Lorraine Olivera-Rivera ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Gastric Banding ◽  
Body Mass ◽  
Laparoscopic Adjustable Gastric Banding ◽  
Adjustable Gastric Banding ◽  
Low Body Mass Index

scholarly journals Coccydynia – could age, trauma and body mass index be independent prognostic factors for outcomes of intervention?

2018 ◽  
Vol 100 (1) ◽  
pp. 12-15 ◽  
Author(s):  
P Kodumuri ◽  
S Raghuvanshi ◽  
R Bommireddy ◽  
Z Klezl
Keyword(s):  
Body Mass Index ◽  
Prognostic Factors ◽  
Body Mass ◽  
Female Gender ◽  
World Health ◽  
Long Term Results ◽  
Significant Difference ◽  
Patient Reported ◽  
Group A ◽  
Manipulation Under Anaesthesia

Introduction The aetiology of coccydynia can be multifactorial, with several associated factors such as obesity, female gender and low mood. The long-term results of operative interventions, such as manipulation under anaesthesia and coccygectomy are variable, ranging from 63–90%. Materials and methods Our aim was to identify whether age, trauma and body mass index (BMI) were independent prognostic factors in coccydynia treatment. All patients who presented to the Royal Derby Hospital with a primary diagnosis of coccydynia between January 2011 and January 2015 who had injections, manipulation under anaesthesia or coccygectomy were included. We used patient-reported satisfaction score as the primary outcome measure. We hypothesised that patients with preceding history of trauma and with high BMI (> 25) would be less satisfied. We divided patient BMI into four groups, following World Health Organization guidelines: group A (18.5–24.9), group B (25–29.9), group C (30–39.9) and group D (> 40). Results A total of 748 patients were diagnosed with coccydynia. Of these, 201 patients had 381 injections, 40 had 98 manipulations under anaesthesia and 9 had coccygectomy. Mean age was 46.4 years; 26% of patients had trauma to the coccyx. The mean time to follow-up was 7.3 months. We found a statistically significant difference (P = 0.03) between satisfaction scores in groups B and D. Patients who had trauma improved significantly (P = 0.04). The odds ratio calculation of coccygectomy and BMI revealed a higher risk of coccygectomy in Group A. Discussion This is the first study to establish BMI and trauma as independent prognostic factors for coccydynia treatment. Our hypothesis that patients with higher BMI would have lower satisfaction levels has been proven true.

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