scholarly journals Diagnosis and management of a full thickness macular hole

2012 ◽  
Vol 74 (3) ◽  
pp. 21
Author(s):  
Nicolas Fontaine ◽  
Sébastien Olivier
Keyword(s):  
Macular Hole ◽  
Clinical Signs ◽  
Classical Case ◽  
Visual Recovery ◽  
Full Thickness ◽  
Current State ◽  
Medical Imagery ◽  
Macular Holes ◽  
Full Thickness Macular Hole ◽  
One Year

Background: First stage macular holes are not always easily identified without the use of medical imagery. Differential diagnosis from other macular conditions is possible with a keen eye and the use of a binocular fundus lens. However, the advent of optical coherence tomography facilitates accurate diagnosis. Case Report: This report demonstrates a classical case of a full thickness macular hole. The clinical signs are not pathognomonic at first, but typical signs develop in the following weeks. The different stages of the disease are described, as well as current state of surgical treatment and possible outcomes. Conclusions: Early diagnosis allows quick visual recovery. Nevertheless, this condition can be treated up to one year after occurrence with significant improvement of visual function.

scholarly journals Characteristics and Risk Factors for Spontaneous Closure of Idiopathic Full-Thickness Macular Hole

2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Xida Liang ◽  
Wu Liu
Keyword(s):  
Risk Factors ◽  
Macular Hole ◽  
Case Reports ◽  
Primary Treatment ◽  
Small Sample ◽  
Spontaneous Closure ◽  
Full Thickness ◽  
Macular Holes ◽  
Pubmed Database ◽  
Full Thickness Macular Hole

Idiopathic full-thickness macular hole is a severe visual impairment disease. Pars plana vitrectomy remains the primary treatment option for idiopathic full-thickness macular holes, and over 90% idiopathic full-thickness macular holes are closed by vitrectomy surgery. However, the full-thickness macular hole may close spontaneously, with a good visual acuity progress. Since recent studies are small-sample studies and case reports, the characteristics for spontaneous closure of idiopathic full-thickness macular holes are not fully understood. Here, we review the articles in PubMed database from 1999 to 2018 and discuss the characteristic and the risk factors, especially OCT structure features, for spontaneous closure of idiopathic full-thickness macular holes.

Arc flash macular hole

2020 ◽  
pp. 112067212097623
Author(s):  
Ruminder Kaur ◽  
Prateek Koul
Keyword(s):  
Laser Beam ◽  
Macular Hole ◽  
Electric Shock ◽  
Light Exposure ◽  
Full Thickness ◽  
Bright Flash ◽  
Macular Holes ◽  
Full Thickness Macular Hole ◽  
History Of ◽  
Arc Flash

Macular holes are common. Lightening, direct electric shock induced and laser beam induced macular holes are though rare. Reporting a case of spark flashlight (Arc Flash) induced macular hole in an electrician, which has never been reported. A 19 year old male electrician by profession presented to our clinic with a history of exposure to a bright flash light from spark of wires while at work that led to decrease of vision in his both eyes. Examination revealed a full thickness macular hole in his right eye and loss of foveal photoreceptors in the left eye. Arc flash light exposure in electricians can lead to macular holes too adding a new entity to the already existing types of macular holes.

scholarly journals Lamellar macular holes: evolving concepts and propensity for progression to full thickness macular hole

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Salim Zafar Asaad
Keyword(s):  
Macular Hole ◽  
Clinical Course ◽  
Morphological Changes ◽  
Wide Spectrum ◽  
Tissue Loss ◽  
Lamellar Macular Hole ◽  
Full Thickness ◽  
Macular Holes ◽  
Full Thickness Macular Hole ◽  
Tractional Forces

Abstract Currently the term lamellar macular hole (LMH) alludes to a wide spectrum of macular conditions including distinct clinical entities with different pathomorphologies. Classifications into subtypes, tractional and degenerative or based on the associated preretinal tissue had been proposed. Recent insights suggest that only lesions with tissue loss should be considered ‘true’ LMH and not those morphological changes caused by tractional forces. Inclusion of lesions with foveoschisis with contractile epiretinal membrane (ERM) in earlier studies on LMHs has resulted in imprecise information about its clinical course. This review provides an overview of the evolving concepts of LMHs and analyses its natural history from study cases in previously published literature.

Vitrectomy with the inverted internal limiting membrane flap technique in eyes with full-thickness macular hole and dry age-related macular degeneration

2020 ◽  
pp. 112067212092137
Author(s):  
Zofia Michalewska ◽  
Jerzy Nawrocki
Keyword(s):  
Visual Acuity ◽  
Macular Degeneration ◽  
Macular Hole ◽  
Internal Limiting Membrane ◽  
Age Related Macular Degeneration ◽  
Full Thickness ◽  
Flap Technique ◽  
Age Related ◽  
Macular Holes ◽  
Full Thickness Macular Hole

Purpose To present effects of the inverted internal limiting membrane flap technique in full-thickness macular holes coexisting with dry age-related macular degeneration. Methods Our database was retrospectively reviewed in order to spot patients with the simultaneous diagnosis of dry age-related macular degeneration and full-thickness macular hole. Vitrectomy with the inverted internal limiting membrane flap technique was performed. Inclusion criteria were full-thickness macular hole, drusen, vitrectomy performed, and spectral domain optical coherence tomography (Copernicus HR, Optopol, Poland) or swept source optical coherence tomography (Triton, Topcon, Japan) before surgery, then 1 week (±3 days), 1 month (±1 week), 3 months (±1 month), 6 months (±1 month), 12 months (±2 months), and 18 months to 12 years after surgery. Main outcome measures Closure of macular hole and visual acuity at the final control. Results A total of 18 eyes of 12 patients (mean age: 68 years) were included. Mean minimum macular hole diameter was 493 μm. Mean maximum macular hole diameter was 1072 μm. Macular hole was closed in 16 eyes after first surgery and in all eyes after second surgery. Improvement of visual acuity was statistically significant ( P = 0.05), but there was no statistical significant correlation observed between initial macular hole diameters and final visual acuity ( P > 0.1). Conclusion The inverted internal limiting membrane flap technique improves anatomical and functional results in eyes with coexisting dry age-related macular degeneration and full-thickness macular holes. Final development of choroidal neovascularization or geographic atrophy is possible in rare cases.

Gliotic tissue simulating a macular neovascularization in full-thickness macular hole

2021 ◽  
pp. 112067212110295
Author(s):  
Chiara Vigano’ ◽  
Enrico Borrelli ◽  
Riccardo Sacconi ◽  
Maria Brambati ◽  
Francesco Bandello ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Retinal Pigment Epithelium ◽  
Macular Hole ◽  
Male Patient ◽  
Vascular Tissue ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Full Thickness ◽  
Macular Holes ◽  
Full Thickness Macular Hole

The authors report a case of a male patient affected by macular hole. In particular, a hyperreflective tissue was found on optical coherence tomography (OCT) examination in macular region, just above the retinal pigment epithelium (RPE). OCT angiography (OCTA) did not show the presence of vascular tissue, thus the hyperreflective material was ascribed to primary gliotic tissue. This case highlights the ability for Müller cells placed near macular holes to migrate up to the RPE and to produce gliotic tissue.

Progression of lamellar macular holes into full-thickness macular hole

2019 ◽  
pp. 42-44
Author(s):  
O. Vedernikova ◽  
◽  
P.M. Shahabutdinova ◽  
D.O Shkvorchenko ◽  
◽  
...  
Keyword(s):  
Macular Hole ◽  
Full Thickness ◽  
Macular Holes ◽  
Full Thickness Macular Hole

scholarly journals Macular profile of eyes developing macular holes in cases of central retinal vein occlusion treated with Bevacizumab

2020 ◽  
Vol 9 (1) ◽  
pp. 13-19
Author(s):  
Anadi Khatri ◽  
Pratap Karki ◽  
Sagun Narayan Joshi ◽  
Bal Kumar Khatri ◽  
Muna Kharel ◽  
...  
Keyword(s):  
Macular Edema ◽  
Macular Hole ◽  
Retinal Vein Occlusion ◽  
Central Retinal Vein Occlusion ◽  
Vascular Endothelial ◽  
Full Thickness ◽  
Vein Occlusion ◽  
Macular Holes ◽  
Full Thickness Macular Hole ◽  
Central Retinal Vein

Background: Anti-vascular endothelial growth factors are commonly used for treatment for central retinal vein occlusion. There have been numerous reports regarding both the benefits and disadvantages of its use. Recently, a rather surprising complication- development of macular holes have started emerging. Objectives: The purpose of this study was to evaluate if the patient's profile, baseline optical coherence tomography parameters, status of the vitreous and subsequent response pose a risk for macular hole formation in cases of central retinal vein occlusion central retinal vein occlusion following treatment with bevacizumab.  Methodology: This prospective exploratory analytical study was conducted at a tertiary eye care center of Nepal and evaluated 97 eyes with central retinal vein occlusion undergoing treatment with bevacizumab. Results: Full Thickness Macular Hole  developed in eight (8.24%) of the central retinal vein occlusion eyes treated with bevacizumab. Elderly age and eyes with cystoid edema at baseline were found to have greater risk of developing macular hole following treatment (OR: 8.97 , p<0.05). Twelve eyes (12.3%) of the eyes treated developed vitreoretinal interface anomalies and were the result of dramatic decrease in central macular thickness . All of them had cystoid macular edema at baseline. Five of them (42%) developed full thickness macular hole. Conclusion: Anti-vascular endothelial growth factor agents have been widely accepted as the first line of choice for treatment of macular edema secondary to central retinal vein occlusion. Cystoid macular edema, eyes of the elderly and those showing dramatic decrease in central macular thickness with the development of anomalous vitreoretinal interface are potential risk factors for full thickness macular hole.

scholarly journals Spontaneous Closure of a Full-Thickness Macular Hole Associated with Proliferative Diabetic Retinopathy and Persistent Vitreomacular Traction

2016 ◽  
Vol 7 (1) ◽  
pp. 163-166 ◽  
Author(s):  
Benjamin J. Reinherz ◽  
Jeffrey S. Rubin
Keyword(s):  
Diabetic Retinopathy ◽  
Macular Hole ◽  
Proliferative Diabetic Retinopathy ◽  
Spontaneous Closure ◽  
Vitreomacular Traction ◽  
Full Thickness ◽  
Macular Holes ◽  
Full Thickness Macular Hole ◽  
Idiopathic Macular Holes

Diabetic retinopathy worsens the prognosis of macular holes compared to those of idiopathic etiology. While spontaneous closure of idiopathic macular holes is a well-documented phenomenon, spontaneous closure of macular holes associated with proliferative diabetic retinopathy is rare. We report a case of spontaneous closure of a macular hole associated with proliferative diabetic retinopathy and persistent vitreomacular traction.

scholarly journals Natural progression of lamellar macular holes in high myopia: a long-term follow-up study

2021 ◽  
Author(s):  
Mary Ho ◽  
Eugenie Mok ◽  
Felix Lai ◽  
Helena PY Sin ◽  
Shaheeda Mohamed ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Acuity ◽  
Macular Hole ◽  
High Myopia ◽  
Full Thickness ◽  
Macular Holes ◽  
Full Thickness Macular Hole ◽  
The Mean

Abstract Background To determine the long-term prognosis of lamellar macular holes (LMH) in highly myopic eyes. Methods This was a retrospective observational study. Patients with LMH associated with high myopia (>-6 dioptres) were examined at regular 6-month intervals for a minimum of 36 months to detect for any structural and functional deterioration. Assessment included visual acuity checking, fundal examination, and optical coherence tomography (OCT) scanning. The risk factors for visual deterioration and progression to full-thickness macular hole (MH) were analysed using Kaplan-Meier survival analysis. The main outcome measures included the changes in mean best-corrected visual acuities, evidence of lamellar hole progression on OCT scans and complication rates of full-thickness macular hole (FTMH), and foveal detachment (FD) development. Results A total of 37 highly myopic eyes with optical coherence tomography confirmed LMH were recruited from 36 patients. The mean age was 63.4 ± 9.8 years and the mean spherical equivalent refractive error was − 9.01 ± 3.6 D with axial length of 27.74 ± 1.45 mm. The mean follow-up duration was 57.6 ± 10.9 months. The mean baseline visual acuity was 0.272 logMAR ± 0.22. A gradual decline in visual acuity was noted, and the change reached statistical significance from 36 months onwards. Visual acuity was 0.648 ± 0.41 logMAR at 36 months (p = 0.034) and 0.604 ± 0.455 at 48 months (p = 0.046). Twelve eyes (32.4%) had foveoschisis at baseline. Coexistence of a lamellar macular hole with foveoschisis was shown to be a risk factor for the development of a FTMH or FD (p = 0.002). Conclusion LMH in highly myopic eyes was generally stable, while a small proportion of patients progressed to full-thickness MH. Patients with coexisting LMH, foveoschisis, and vitreomacular traction had a higher risk of visual decline and progression to full-thickness MH.

scholarly journals Changes in each retinal layer and ellipsoid zone recovery after full-thickness macular hole surgery

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Min-Woo Lee ◽  
Tae-Yeon Kim ◽  
Yong-Yeon Song ◽  
Seung-Kook Baek ◽  
Young-Hoon Lee
Keyword(s):  
Macular Hole ◽  
Axial Length ◽  
Outer Nuclear Layer ◽  
Plexiform Layer ◽  
Retinal Layer ◽  
Inner Plexiform Layer ◽  
Full Thickness ◽  
Ellipsoid Zone ◽  
Full Thickness Macular Hole ◽  
Fellow Eyes

AbstractTo analyze the changes in each retinal layer and the recovery of the ellipsoid zone (EZ) after full-thickness macular hole (FTMH) surgery. Patients who underwent surgery for FTMH were included. Spectral-domain optical coherence tomography (SD-OCT) was performed preoperatively and postoperatively at 1, 3, 6, 9, and 12 months. A total of 32 eyes were enrolled. Ganglion cell layer, inner plexiform layer, and inner nuclear layer showed significant reductions over time after surgery (P = 0.020, P = 0.001, and P = 0.001, respectively), but were significantly thicker than those of fellow eyes at 12 months postoperatively. The average recovery duration of the external limiting membrane (ELM), outer nuclear layer (ONL), and EZ was 1.5, 2.1, and 6.1 months, respectively. Baseline best-corrected visual acuity (BCVA) (P = 0.003), minimum linear diameter (MLD) (P = 0.025), recovery of EZ (P = 0.008), and IRL thickness (P < 0.001) were significant factors associated with changes in the BCVA. Additionally, axial length (P < 0.001), MLD (P = 0.020), and IRL thickness (P = 0.001) showed significant results associated with EZ recovery. The IRL gradually became thinner after FTMH surgery but was still thicker than that of the fellow eye at 12 months postoperatively. The recovery of ELM and ONL may be a prerequisite for the EZ recovery. The BCVA change was affected by baseline BCVA, MLD, recovery of EZ, and IRL thickness. Additionally, axial length, MLD, and IRL thickness were significantly associated with EZ recovery.

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