Pediatric Ophthalmology for Primary Care, 3rd Ed

2007 ◽  
Author(s):  
Kenneth W. Wright
Keyword(s):  
Treatment Approach ◽  
Pediatric Ophthalmology ◽  
Genetic Syndromes ◽  
Full Spectrum ◽  
Resource Manual ◽  
Clinic Foundation ◽  
New Information ◽  
Eye Disorders ◽  
Effective Diagnosis ◽  
Clinical Resource

Formatted for practical problem solving, the new 3rd edition of this clinical resource manual covers the full spectrum of eye disorders, eye examinations, vision screening, strabismus, dyslexia, ocular trauma, genetic syndromes, and all the diverse pediatric-specific eye disorders you are likely to encounter. "This book is a useful and well presented source of pediatric ophthalmology. The excellent photos are clear and crisp." Stephen Mikell, MD, Ochsner Clinic Foundation, Doody's Review, 2008. Clear, concise explanations and recommendations are complemented by numerous figures and photographs demonstrating eye pathology. Includes more than 200 color images; ready access to expert guidance through all the steps in effective diagnosis and intervention, including laboratory workup, etiology, differential diagnosis, preferred treatment approach, clinical course, prognosis, and indications for referral; expanded chapter on amblyopia and strabismus; new information on the importance of maintaining physiologic hypoxia; and down syndrome.

Pediatric Ophthalmology for Primary Care

2019 ◽  
Author(s):  
Kenneth W. Wright ◽  
Yi Ning Strube
Keyword(s):  
Primary Care ◽  
Primary Care Physicians ◽  
Ocular Trauma ◽  
Vision Screening ◽  
Pediatric Ophthalmology ◽  
Genetic Syndromes ◽  
Fourth Edition ◽  
Eye Disorders

Completely updated and revised, the fourth edition provides primary care physicians with must-know information on eye examinations, eye disorders, vision screening, strabismus, dyslexia, ocular trauma, genetic syndromes, and all pediatric-specific eye issues likely to be encountered in primary care. https://shop.aap.org/pediatric-ophthalmology-for-primary-care-paperback/

Discovery Informatics

2011 ◽  
pp. 387-391
Author(s):  
William W. Agresti
Keyword(s):  
Science And Technology ◽  
Data Sources ◽  
Massive Data ◽  
Full Spectrum ◽  
Analytical Science ◽  
Research And Practice ◽  
Making Sense ◽  
New Information

Discovery informatics is an emerging methodology that brings together several threads of research and practice aimed at making sense out of massive data sources. It is defined as “the study and practice of employing the full spectrum of computing and analytical science and technology to the singular pursuit of discovering new information by identifying and validating patterns in data” (Agresti, 2003).

When to Play Your Advertisement? Optimal Insertion Policy of Behavioral Advertisement

2020 ◽  
Vol 31 (2) ◽  
pp. 589-606 ◽  
Author(s):  
Subodha Kumar ◽  
Yinliang (Ricky) Tan ◽  
Lai Wei
Keyword(s):  
Price Discrimination ◽  
Simulation Study ◽  
Optimal Policy ◽  
Target Level ◽  
Full Spectrum ◽  
Threshold Policy ◽  
Wearable Technologies ◽  
Display Advertising ◽  
New Information ◽  
Wide Range

Digital advertisements offer a full spectrum of behavioral customization for timing and content capabilities. The existing research in display advertising has predominantly concentrated on the content of advertising; however, our focus is on optimizing the timing of display advertising. In practice, users are constantly adjusting their engagement with content as they process new information continuously. The recent development of emotional tracking and wearable technologies allows platforms to monitor the user’s engagement in real time. The proposed optimal policy regarding the timing of behavioral advertising is based on a threshold policy with a trigger threshold and target level. Analogous to the familiar idea of “price discrimination,” the methods we propose in this study allow the platforms to maximize their revenue by “discriminatory” customization of the timing and length of the advertisement based on the behavior of individual users. Finally, we quantify the benefits of the proposed policy by comparing it with the practically prevalent policies (i.e., preroll, midroll, and a mix of the two) through a simulation study. Our results reveal that, for a wide range of settings, the proposed policy not only significantly increases the platform’s profitability but also improves the completion rate at which consumers finish viewing the advertisement.

scholarly journals Development of GUI for Detetection of Eye Disorders in Infants

2021 ◽  
Vol 12 (11) ◽  
pp. 1980-1985
Author(s):  
Aditya Singh, Et. al.
Keyword(s):  
Depth Perception ◽  
Labor Cost ◽  
Diagnostic Information ◽  
Pediatric Ophthalmology ◽  
Image Processing Techniques ◽  
Eye Disorders ◽  
Reduce Labor Cost ◽  
Icd 10 ◽  
Processing Techniques ◽  
Common Vision

Strabismus is one of the most common vision diseases in which the eyes do not properly align with each other when looking at an object. The condition may be present occasionally or constantly and if it is present during a large part of childhood, it may result in amblyopia or loss of depth perception. In contrast to manual diagnosis, automatic recognition can significantly reduce labor cost and increase diagnosis efficiency. In this paper, we propose to detect ICD-10-CM Code H50.9 unspecified strabismus using CNN and Image Processing techniques. There are four types of strabismus namely exotropia, esotropia, hypertropia and hypotropia which we aim to detect. We furthermore aim to introduce a GUI particularly into pediatric ophthalmology where obtaining relevant diagnostic information is taxing.

scholarly journals A review of ocular genetics and inherited eye diseases

2012 ◽  
Vol 71 (4) ◽  
Author(s):  
S. D. Mathebula
Keyword(s):  
Visual Impairment ◽  
Genetic Diseases ◽  
Developed Countries ◽  
Eye Diseases ◽  
Visual Aids ◽  
Genetic Syndromes ◽  
Management Options ◽  
Molecular Features ◽  
Eye Disorders ◽  
Hereditary Component

During the past twenty years, there has been an exponential increase in the knowledge and under-standing of ocular genetic diseases and syndromes. The number of human eye diseases that have a known genetic or hereditary component continues to increase. In addition, genetic diseases are the most common cause of blindness in infants and children in developed countries. Optometrists are likely to encounter patients with inherited eye disorders. They may be the first clinician the patient consults. Inherited eye diseases may be isolated (only affecting the eye) or part of a complicated syndrome. Both isolated eye diseases and genetic syndromes can have identifiable gene mutation known to cause the disease.Knowledge of the clinical and molecular features of ocular genetics and inherited eye diseases is important for appropriate diagnosis and patient management. This article reviews the current information on ocular genetics and inherited eye diseases.The ocular conditions described in the review have significant visual impairment and blindness consequences. Therefore, optometrists (as the mostly likely first line of consultation) should be able todiagnose the condition appropriately first before they could make any management, care or referralplan. Visual aids are, of course, one of the management options for such patients with visual impairment. (S Afr Optom 2012 71(4) 178-189)

scholarly journals Eye Disorders Spectrum: A Tertiary Hospital Pediatric Ophthalmology Clinic Based in Ethiopia

2021 ◽  
Author(s):  
Yohannes Tewolde Kidane ◽  
Addisu Worku Teshome
Keyword(s):  
Addis Ababa ◽  
Ocular Motility ◽  
Pediatric Ophthalmology ◽  
Health Care Planning ◽  
Early Presentation ◽  
Eye Disorders ◽  
Tertiary Teaching ◽  
Ocular Disorders ◽  
Infection And Inflammation ◽  
Childhood Cataract

Abstract Background: Epidemiological studies to determine the pattern of eye disorders among children are important for proper health care planning and management. This study aimed to document the spectrum and frequency of eye diseases of children who attended the pediatric ophthalmology clinic of a tertiary teaching hospital Addis Ababa, Ethiopia. Methods: A cross sectional and convenient sample of 1237, male and female children (16 years and below) with ocular disorders presenting for the first time and those children with settled diagnosis coming for follow up visit between June 1, 2018 to May 31, 2019 were included in the study. Data on age at presentation, sex and diagnosis were collected and analyzed. Eye disorders were classified into various categories. Children were grouped into four age groups. Ratios, percentages and chi square associations were calculated. P< 0.05 was considered statistically significant.Results: Of the children 60% were male. The mean age (standard deviation) of the children was 4.26 (+4.1) years. Patients aged 0–5 years old were the largest group constituting 70.5%. Ocular motility imbalances were the most common ocular disorders seen (32.8 %), followed by childhood cataract (18.4%) and infection and inflammation of eye and adnexa (8.3%). Ocular motility imbalances were recorded more frequently and statistically significant (p < 0.001) among 1­ 5 years age group. Within the childhood cataract category, congenital cataract was more prominent (7.1%). Within the infection and inflammation category, cornea/ sclera infections were more common (3.7%). Conclusions: The study highlights common eye disorders seen in children in a specialized hospital ophthalmic clinic. Ocular motility imbalance, childhood cataract, and infection and inflammation of the eye and adnexa, were the most common occurring disorders. Early presentation was common, and males were more affected than females.

Islamic Ceramics and Rural Economy in the Trapani Mountains during the 11th century

2020 ◽  
Vol 7 (1) ◽  
pp. 39-77
Author(s):  
Viva Sacco ◽  
Veronica Testolini ◽  
José Maria Martin Civantos ◽  
Peter M. Day
Keyword(s):  
Communities Of Practice ◽  
Rural Economy ◽  
Rural Site ◽  
Full Spectrum ◽  
North West ◽  
Consumption Choices ◽  
New Information ◽  
A Site ◽  
Economic Ties ◽  
Integrated Study

Located in the Trapani Mountains of North-West Sicily, the hilltop site of Pizzo Monaco hasformed the focus of systematic excavation and an innovative, integrated study of the totalceramic assemblage, as part of the MEMOLA FP7 project. The date, provenance and productiontechnology of the varied types of pottery are investigated by macroscopic, morphological anddecorative analysis, in combination with petrography and scanning electron microscopy in orderto assess social, technological and economic ties of this rural site and its environs with the earlyIslamic capital of Sicily at Palermo, the wider island and North Africa. Local production of cookingvessels is compared with glazed and plain storage pottery, serving and consumption vesselsfrom Palermo, in a region where the new relationship between coastal centre and nearby mountaineconomies was being forged. Correlation of the properties of the pottery assemblage withthe unusual architecture suggests the storage of a repeated ceramic set, perhaps on a householdbasis, in a site which may be a fortified storage facility, rather than sustaining more permanentoccupation. The typological study provides new information on the range of ceramics circulatingin Sicily during the mid-11th century CE, revealing the full spectrum of ceramics consumedat this time. This approach contrasts with work that privileges a view of simple transmissionof glazing technologies across the Islamic Mediterranean. Indeed a comparison of productionsequences in the crafting of similar glazed bowls at Palermo demonstrates the co-existence ofdifferent communities of practice and cautions against over-simplified reconstructions of thetransmission of glazing technologies in the early medieval Mediterranean. The range of potteryavailable from a variety of sources highlights the consumption choices made by these communitiesin the medieval period.

scholarly journals Genomic landscape of pancreatic neuroendocrine tumours: the International Cancer Genome Consortium

2018 ◽  
Vol 236 (3) ◽  
pp. R161-R167 ◽  
Author(s):  
Andrea Mafficini ◽  
Aldo Scarpa
Keyword(s):  
Neuroendocrine Tumours ◽  
Genetic Alterations ◽  
Cancer Genome ◽  
The Body ◽  
Genetic Syndromes ◽  
International Cancer Genome Consortium ◽  
Molecular Alterations ◽  
New Information ◽  
Pancreatic Neuroendocrine Tumours ◽  
Genome Consortium

Neuroendocrine tumours (NETs) may arise throughout the body and are a highly heterogeneous, relatively rare class of neoplasms difficult to study also for the lack of disease models. Despite this, knowledge on their molecular alterations has expanded in the latest years, also building from genetic syndromes causing their onset. Pancreatic NETs (PanNETs) have been among the most studied, and research so far has outlined a series of recurring features, as inactivation of MEN1, VHL, TSC1/2 genes and hyperactivation of the PI3K/mTOR pathway. Next-generation sequencing has added new information by showing the key role of alternative lengthening of telomeres, driven in a fraction of PanNETs by inactivation of ATRX/DAXX. Despite this accumulation of knowledge, single studies often relied on few cases or were limited to the DNA, RNA, protein or epigenetic level with lack of integrative analysis. The International Cancer Genome Consortium aimed at removing these barriers through a strict process of data and samples collection, to produce whole-genome integrated analyses for many tumour types. The results of this effort on PanNETs have been recently published and, while confirming previous observations provide a first snapshot of how heterogeneous is the combination of genetic alterations that drive this tumour type, yet converging into four pathways whose alteration has been enriched by newly discovered mechanisms. While calling for further integration of genetic and epigenetic analyses, these data allow to reconcile previous findings in a defined frame and may provide clinical research with markers for patients stratification and to guide targeted therapy decisions.

scholarly journals Current molecular understanding of Axenfeld–Rieger syndrome

2005 ◽  
Vol 7 (25) ◽  
pp. 1-17 ◽  
Author(s):  
Tord A. Hjalt ◽  
Elena V. Semina
Keyword(s):  
Open Angle Glaucoma ◽  
Biological Properties ◽  
Full Spectrum ◽  
Rieger Syndrome ◽  
Complete Penetrance ◽  
Main Challenge ◽  
Eye Disorders ◽  
Homeobox Transcription Factor ◽  
Polarity Determination ◽  
Correct Function

Axenfeld–Rieger syndrome (ARS) is a rare autosomal dominant inherited disorder affecting the development of the eyes, teeth and abdomen. The syndrome is characterised by complete penetrance but variable expressivity. The ocular component of the ARS phenotype has acquired most clinical attention and has been dissected into a spectrum of developmental eye disorders, of which open-angle glaucoma represents the main challenge in terms of treatment. Mutations in several chromosomal loci have been implicated in ARS, including PITX2, FOXC1 and PAX6. Full-spectrum ARS is caused primarily by mutations in the PITX2 gene. The homeobox transcription factor PITX2 is produced as at least four different transcriptional and splicing isoforms, with different biological properties. Intriguingly, PITX2 is also involved in left–right polarity determination, although asymmetry defects are not a feature of ARS. In experimental animal models and in cell culture experiments using PITX2, abundant evidence indicates that a narrow window of expression level of this gene is vital for its correct function.

Discovery Informatics from Data to Knowledge

2011 ◽  
pp. 676-682
Author(s):  
William W. Agresti
Keyword(s):  
21St Century ◽  
Science And Technology ◽  
Data Sources ◽  
Massive Data ◽  
Full Spectrum ◽  
Analytical Science ◽  
Research And Practice ◽  
Making Sense ◽  
New Information

It is routine to hear and read about the information explosion, how we are all overwhelmed with data and information. Is it progress when our search tools report that our query resulted in 300,000 hits? Or, are we still left to wonder where is the information that we really wanted? How far down the list must we go to find it? Discovery informatics is a distinctly 21st century emerging methodology that brings together several threads of research and practice aimed at making sense out of massive data sources. It is defined as “the study and practice of employing the full spectrum of computing and analytical science and technology to the singular pursuit of discovering new information by identifying and validating patterns in data” (Agresti, 2003).

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