Child Versus Adult Research: The Gap in High-Quality Study Design

PEDIATRICS ◽  
2008 ◽  
Vol 122 (1) ◽  
pp. 52-57 ◽  
Author(s):  
C. Martinez-Castaldi ◽  
M. Silverstein ◽  
H. Bauchner
Keyword(s):  
Study Design ◽  
High Quality ◽  
High Quality Study ◽  
Quality Study

Message from Editors-in-Chief

2017 ◽  
Vol 12 (3) ◽  
pp. 393-393
Author(s):  
Haruo Hayashi ◽  
Keyword(s):  
Risk Reduction ◽  
Disaster Risk Reduction ◽  
Chief Editor ◽  
Disaster Risk ◽  
Disaster Reduction ◽  
Disaster Research ◽  
High Quality ◽  
Professional Journal ◽  
High Quality Study ◽  
Quality Study

Journal of Disaster Research (JDR) is a comprehensive, peer-reviewed professional journal published in Japan for studies on disaster reduction with all-hazard approach and has published more than 1,000 papers since 2006. I took over the chief editor from Dr. Takiguchi last September to help Dr. Murakami. I would like to keep working on publishing high-quality study achievements from JDR, as a clearinghouse site of disaster risk reduction and resilience information in Asia. I very much hope for your continued cooperation.

Kriteria Empirik dalam Menentukan Ukuran Sampel Pada Pengujian Hipotesis Statistika dan Analisis Butir

2015 ◽  
Vol 2 (2) ◽  
Author(s):  
Idrus Alwi
Keyword(s):  
Sample Size ◽  
Statistical Study ◽  
Item Analysis ◽  
Main Issue ◽  
Sample Size Determination ◽  
Size Determination ◽  
High Quality ◽  
High Quality Study ◽  
Quality Study ◽  
Real Goal

<p>Sample-size determination is often an important step in planning statistical study and item analysis and it is usually a difficult one. Among the important hurdles to surpassed, one must obtain an estimate of one or more error variances, and specify an effects size of importance. There is the temptation to take some shortcuts. This paper offers some suggestions for successful and meaningful sample-size determination. Also discussed is the possibility that sample-size may not be the main issue, that the real goal is to design a high-quality study. Finnaly, criticism is made of some ill-advised shortcuts relating to power and sample-size. <br /><br /></p>

Association between sense of coherence and dental caries: systematic review and meta-analysis

2019 ◽  
Vol 35 (3) ◽  
pp. 586-597 ◽  
Author(s):  
Thaís Ariane Perdigão Torres ◽  
Larissa Corradi-Dias ◽  
Patrícia Drummond Oliveira ◽  
Carolina Castro Martins ◽  
Saul Martins Paiva ◽  
...  
Keyword(s):  
Systematic Review ◽  
Dental Caries ◽  
Quality Assessment ◽  
Sense Of Coherence ◽  
Web Of Science ◽  
Meta Analysis ◽  
Reference List ◽  
High Quality ◽  
Hand Search ◽  
Quality Study

Abstract Sense of coherence (SOC) is regarded as the individuals' capacity for managing the stressors over their lifespan. The aim of this systematic review and meta-analysis was to evaluate the association between SOC and dental caries. Electronic searchers were conducted in six databases: PubMed, Medline, Scopus, Web of Science, Lilacs and Proquest from their date of inception until November/2017. An update took place in August/2018. A hand search in the reference list of the included articles and gray literature search were also carried out. Retrieved titles/abstracts were screened by two review authors. Data of the included articles were extracted and quality assessment was also conducted. The first search retrieved 346 titles/abstracts. The update retrieved 33 records. Following the removal of 70 duplicates, 309 references were screened and 17 were included. The quality assessment ranged from low quality articles to high quality articles. High quality study showed that adult individuals with lower SOC were more likely to have dental caries. Meta-analysis showed that adolescents with low SOC were 5.41 times more likely to present dental caries than adolescents with high SOC (CI = 2.15–13.59). Mothers with low SOC were 5.55 times more likely to have children/adolescents with dental caries than mothers with high SOC (CI = 2.92–10.57). The subgroup analysis exploring continuous data showed that the SOC of mothers of children/adolescents without dental caries was significantly higher than the SOC of mothers of children/adolescents with dental caries (CI = 0.10–0.51). Higher levels of SOC seem to be associated with lower levels of dental caries.

P0502BIOBANKING FOR GLOMERULAR DISEASES: A STUDY DESIGN AND PROTOCOL FOR KOREA RENAL BIOBANK NETWORK SYSTEM TOWARD NEXT-GENERATION ANALYSIS (KORNERSTONE)

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Eunjeong Kang ◽  
Yaerim Kim ◽  
Yong Chul Kim ◽  
Soojin Lee ◽  
Seungyeup Han ◽  
...  
Keyword(s):  
Cohort Study ◽  
Study Design ◽  
Clinical Data ◽  
Kidney Biopsy ◽  
Network System ◽  
Next Generation ◽  
High Quality ◽  
Glomerular Diseases ◽  
Treatment Targets ◽  
Novel Treatment

Abstract Background and Aims Glomerular diseases, a set of debilitating and complex disease entities, are related to mortality and morbidity. To gain insight into pathophysiology and novel treatment targets of glomerular disease, various types of biospecimens linked to deep clinical phenotyping including clinical information, digital pathology, and well-defined outcomes are required. We provide the rationale and design of the KOrea Renal biobank NEtwoRk System TOward Next-generation analysis (KORNERSTONE). Method The KORNERSTONE, which has been initiated by Korea Centres for Disease Control and Prevention, is designed as a multi-centre, prospective cohort study and biobank for glomerular diseases. Clinical data, questionnaires will be collected at the time of kidney biopsy and subsequently every one year after kidney biopsy. All of the clinical data will be extracted from the electrical health record and automatically uploaded to the web-based database. High-quality digital pathologies are obtained and connected in the database. Various types of biospecimens are collected at baseline and during follow-up: serum, urine, buffy coat, stool, glomerular complementary DNA (cDNA), tubulointerstitial cDNA. All data and biospecimens are processed and stored in a standardised manner. The primary outcomes are mortality and end-stage renal disease. The secondary outcomes will be deterioration renal function, remission of proteinuria, cardiovascular events and quality of life. Disussion Ethical approval has been obtained from the institutional review board of each participating centre and ethics oversight committee. The KORNERSTONE is designed to deliver pioneer insights into glomerular diseases. The study design allows comprehensive, integrated and high-quality data collection on baseline laboratory findings, clinical outcomes including administrative data and digital pathologic images. This may provide various biospecimens and information to many researchers, establish the rationale for future more individualised treatment strategies for glomerular diseases. Conclusion In conclusion, we describe the objectives and clinical protocol for the KORNERSTONE. As the first large-scale glomerulonephropathy cohort study with the integration of clinical data, biospecimens and digital pathologic images in Korea, the KORNERSTONE will help to clarify the natural course, complication profiles, and novel treatment targets of the Asian population with glomerular disease.

scholarly journals Meta-Analysis of The Association Between Gene Mutation and Tumor Spread Through Air Space in Lung Adenocarcinoma

2021 ◽  
Author(s):  
Guishi Wang ◽  
Bingfu Li ◽  
Zhang Dingqian ◽  
Zhenyv He ◽  
Tiantian Wang ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Gene Mutation ◽  
Meta Analysis ◽  
High Quality ◽  
Tumor Spread ◽  
Preoperative Prediction ◽  
Air Space ◽  
Quality Study ◽  
Statistical Results

Abstract Background A series of studies have shown that spread through air spaces (STAS) has a significant effect on surgical outcomes in patients with lung adenocarcinoma. Objectives: The aims of this study are to evaluate the association between gene mutation and STAS in lung adenocarcinoma for preoperative prediction of STAS in lung adenocarcinoma, eventually, which could help us choose appropriate surgical type. Methods The retrieval period was from 2015 to December 2020. The Newcastle-Ottawa quality assessment scale (NOS) was used for assessing the quality of each study. High-quality study was defined as those with ≥6 stars at the NOS. Statistical results were analyzed using the Stata16 statistical package. Results A total of 12 studies were included, including 4790 patients. The results of meta-analysis showed that: In patients with lung adenocarcinoma, the expression of EGFR, KRAS, BRAF, ALK and ROS1 were correlated with the occurrence of STAS, with RR values (95%CI) of 0.75 (0.63~0.90), 1.173 (1.00~1.37), 2.116 (1.17~3.84), 1.71 (1.53~1.90), 1.565 (1.35~1.82), respectively. Conclusion Mutations in KRAS, BRAF, ALK, and ROS1 increase the incidence of STAS in patients with lung adenocarcinoma. Mutations in EGFR decrease the incidence of STAS in patients with lung adenocarcinoma.

scholarly journals Shoot and Post: The Making of Educational Videos

2020 ◽  
Vol 5 ◽  
pp. 247275122096616
Author(s):  
Jaee M. Naik ◽  
Florian M. Thieringer ◽  
Benedicta Beck-Broichsitter ◽  
Sabine Girod ◽  
Milind N. Naik
Keyword(s):  
Social Media ◽  
Study Design ◽  
Educational Video ◽  
High Quality ◽  
Personal Experiences ◽  
Photo Documentation ◽  
Social Media Platforms ◽  
Educational Videos ◽  
The Creation

Study Design: Descriptive technical write-up. Objective: To describe the making of educational videos in 4 simple steps. Methods: There are 4 steps in the creation of an educational video, namely theme and script, preparation and equipment, filming, and postproduction. Results: The authors give details of each step of the video making process, with practical tips from personal experiences, product suggestions, and photo documentation. Conclusion: A 4-step approach to make high-quality educational videos for your patients, residents, and social media platforms is presented.

scholarly journals Hip Osteoarthritis and Physical Workload: Influence of Study Quality on Risk Estimations—A Meta-Analysis of Epidemiological Findings

2019 ◽  
Vol 16 (3) ◽  
pp. 322 ◽  
Author(s):  
Yi Sun ◽  
Annette Nold ◽  
Ulrich Glitsch ◽  
Frank Bochmann
Keyword(s):  
Study Design ◽  
Critical Evaluation ◽  
Hip Osteoarthritis ◽  
Physical Workload ◽  
Study Quality ◽  
Design Quality ◽  
High Quality ◽  
Incidence Studies ◽  
Lower Effect ◽  
Occupational Workload

In this paper, we critically evaluate the quality of epidemiological evidence on hip osteoarthritis and workload published so far. The influence of study quality on risk estimations was analyzed in sensitivity meta-analyses and meta-regression analyses. Comprehensive searches for epidemiological studies of hip osteoarthritis and occupational workload were performed in literature databases and current reviews. All studies were assessed on the basis of study design, defined quality scores, and relevant confounders considered. In total, 34 suitable studies were identified for critical evaluation. Of these, 20 are prevalence studies and 14 incidence studies. Strong heterogeneity is observed in study design, quality level, and estimated exposure parameters. A consistent positive association between heavy physical workload and hip osteoarthritis was observed only among the male populations, not among the female populations. In general, cohort studies provided lower effect estimates than cross-sectional and population-based case-control studies. Studies with high quality scores also produced lower effect estimates than studies with low quality scores. Consideration of BMI as a confounder in published studies also yielded lower effect estimates than studies without consideration of BMI as a confounder. Our analyses indicate that high-quality studies of the association between occupational workload and hip osteoarthritis provide lower effect estimates than studies of lower quality.

scholarly journals Going It Alone: Developing An Independent Study Abroad Program

2006 ◽  
Vol 3 (2) ◽  
Author(s):  
Rusty L. Juban ◽  
Aristides R. Baraya ◽  
Michael Craig Budden
Keyword(s):  
Study Abroad ◽  
Business Students ◽  
Independent Study ◽  
Viable Option ◽  
Study Abroad Programs ◽  
High Quality ◽  
Business Programs ◽  
Quality Study ◽  
Faculty And Administrators ◽  
Study Abroad Program

With a greater focus on internationalization, today’s business students are encouraged to participate in study abroad programs.  For smaller, regional business programs seeking a quality study abroad program, faculty and administrators may view “piggybacking” onto existing programs of larger universities as their only viable option.  However, piggyback participation in external programs may require that a university forsake its own standards and objectives, and accept the objectives of other study abroad programs.   Building on the experiences of one university’s study abroad program for MBAs, the idea that piggybacking onto other schools is the only means of creating a high quality international experience for students is rejected.

Sign in / Sign up

Export Citation Format

Share Document