THE FEP (FREE ERYTHROCYTE PORPHYRINS) TEST: A SCREENING MICROMETHOD FOR LEAD POISONING

PEDIATRICS ◽  
1973 ◽  
Vol 51 (2) ◽  
pp. 254-259
Author(s):  
Sergio Piomelli ◽  
Bernard Davidow ◽  
Vincent F. Guinee ◽  
Patricia Young ◽  
Giselle Gay
Keyword(s):  
New York ◽  
New York City ◽  
Lead Poisoning ◽  
York City ◽  
Clinical Laboratory ◽  
Biological Indicator ◽  
Rapid Screening ◽  
Department Of Health ◽  
Blood Specimens ◽  
Test Increase

The FEP test is a micromethod that measures rapidly and reliably free erythrocyte porphyrins in a blood sample of 20µl. The results of the FEP test increase exponentially with the blood Pb level. The FEP test was performed in 1,038 blood specimens submitted to the New York City Department of Health Bureau of Laboratories for Pb analysis. Of these, 568 had Pb levels ≥ 40µg/100 ml. The concentration of FEP was higher than 250µg/100 ml RBC (positive FEP test) in all the samples with greatly increased blood Pb level (≥ 60µg/100 ml), in 55.1% of those with ambiguous blood Pb level (40 to 59µg/100 ml), and in 5.1% of those with low Pb level (< 40µg/100 ml). The FEP test provides a biological indicator of undue lead absorption, suitable for rapid screening of children for lead poisoning. The test can easily be performed by any clinical laboratory.

A STUDY OF PICA IN RELATION TO LEAD POISONING

PEDIATRICS ◽  
1958 ◽  
Vol 22 (4) ◽  
pp. 756-760
Author(s):  
Morris Greenberg ◽  
Harold Jacobziner ◽  
Mary C. McLaughlin ◽  
Harold T. Fuerst ◽  
Ottavio Pellitteri
Keyword(s):  
New York ◽  
New York City ◽  
Child Health ◽  
Lead Poisoning ◽  
York City ◽  
Case Finding ◽  
Department Of Health ◽  
Symptoms And Signs ◽  
Finding Method

During 1956 and 1957 all children under the care of the child health stations of the Department of Health in New York City, who manifested pica, were examined for symptoms and signs of lead poisoning. A blood specimen was taken and tested for lead content; if the concentration of lead was 0.06 mg/100 ml or higher, the child was referred to a doctor for diagnosis and treatment. Among 194 children with pica, there were 28 cases and 20 probable cases of lead poisoning. The follow-up of children with pica is a good case-finding method for lead poisoning.

scholarly journals 440. Clinical Characteristics of Early Noncritical Hospitalized Patients with Coronavirus Disease 2019 (COVID-19): A Single-Center Retrospective Study in New York City

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S287-S288
Author(s):  
Michelle Lee ◽  
Mona Fayad ◽  
Tarub Mabud ◽  
Paulino Tallon de Lara ◽  
Adiac Espinosa Hernandez ◽  
...  
Keyword(s):  
New York ◽  
New York City ◽  
York City ◽  
Clinical Laboratory ◽  
Clinical Symptoms ◽  
New York State ◽  
General Medicine ◽  
Retrospective Chart Review ◽  
Clinical Severity ◽  
Study Cohort

Abstract Background COVID-19 first originated in Wuhan, China, in December 2019. As of April 9, 2020, New York State had become the single largest global epicenter of COVID-19. Methods This is a retrospective chart review of the first 33 patients with RT-PCR-confirmed COVID-19 admitted from the emergency department to a general medicine unit in a single academic hospital in New York City between March 11th to March 27th, 2020. Patient’s demographic, clinical, laboratory, radiographic investigations, treatments and clinical outcomes were retrospectively extracted from the electronic medical record and followed until April 10th, 2020. Patients were divided into severe and nonsevere sub-cohorts. Statistics were descriptive in nature. Results The study cohort (median age 68 yr, 67% male) presented with subjective fevers (82%), cough (88%), and dyspnea (76%). The median incubation period was 3 days. Most cases met SIRS criteria upon admission (76%). Patients had elevated inflammatory markers. Patients were treated with antimicrobials, corticosteroids, hydroxychloroquine, and varying levels of supplemental oxygen. Mortality was 15% and 18% of the cohort required intensive care services. Conclusion Patient age, presenting clinical symptoms, comorbidity profile, laboratory biomarkers, and radiographic features are consistent with findings published from China. Severe patients had peaks in inflammatory biomarkers later in the hospitalization, which may be useful to trend. Further studies are necessary to create guidelines to better risk-stratify COVID-19 patients based on clinical severity. Disclosures All Authors: No reported disclosures

The fate of children vaccinated against tuberculosis according to Salmett's method

1935 ◽  
Vol 31 (1) ◽  
pp. 145-145
Author(s):  
C. Kereszturi ◽  
W. Н. Park ◽  
P. Vogel ◽  
М. Sevine
Keyword(s):  
New York ◽  
New York City ◽  
York City ◽  
Financial Assistance ◽  
Insurance Company ◽  
Careful Observation ◽  
York City Department ◽  
Department Of Health

With financial assistance from the New York City Department of Health and an insurance company, and with the participation of a significant number of technicians, they carried out a study that is noteworthy for the careful observation.

scholarly journals Post-SARS-CoV-2 monoclonal antibody treatment hospitalizations as a sentinel for emergence of viral variants in New York City

2021 ◽  
Author(s):  
Kelsie Cowman ◽  
Yi Guo ◽  
Liise-anne Pirofski ◽  
David Wong ◽  
Hongkai Bao ◽  
...  
Keyword(s):  
New York ◽  
Monoclonal Antibody ◽  
New York City ◽  
York City ◽  
Human Services ◽  
Antibody Treatment ◽  
Health And Human Services ◽  
Department Of Health ◽  
Monoclonal Antibody Treatment ◽  
The U.S

Abstract We partnered with the U.S. Department of Health and Human Services to treat high-risk, non-admitted COVID-19 patients with bamlanivimab in the Bronx, NY per Emergency Use Authorization criteria. Increasing post-treatment hospitalizations were observed monthly between December 2020-March 2021 in parallel to the emergence of SARS-CoV-2 variants in New York City.

scholarly journals Completeness of Pediatric TB Reporting in New York City

2003 ◽  
Vol 118 (2) ◽  
pp. 144-153 ◽  
Author(s):  
Pablo San Gabriel ◽  
Lisa Saiman ◽  
Katherine Kaye ◽  
Muriel Silin ◽  
Ida Onorato ◽  
...  
Keyword(s):  
New York ◽  
New York City ◽  
York City ◽  
Medical Records ◽  
Clinical Characteristics ◽  
Gastric Aspirate ◽  
Department Of Health ◽  
Recent Transmission ◽  
Pediatric Tb ◽  
Completeness Of Reporting

Objectives. Accurate surveillance of tuberculosis (TB) in children is critical because such cases represent recent transmission, but surveillance is difficult as only 10% to 50% of cases are culture-confirmed. Hospital-based sources were used to develop alternative surveillance to assess completeness of reporting for pediatric TB in northern Manhattan and Harlem from 1993 through 1995. Methods. Alternative surveillance sources included ICD-9-CM hospital discharge codes for active TB and gastric aspirate reports. Cases identified by alternative surveillance were compared with cases previously reported to the New York City Department of Health (NYC DOH). Results. Alternative surveillance detected 25 cases of possible pediatric TB, of which four (16%) had never been reported to the NYC DOH and three (12%) had been reported as suspect cases, but had not fulfilled the criteria for a reportable case of pediatric TB. Of these seven newly counted cases, three were detected by ICD-9-CM codes, three by a gastric aspirate log book, and one by both. In contrast, 13 other cases had been reported to the NYC DOH, but were undetected by our alternative surveillance; eight of these could be verified with available medical records. Thus, the demographic and clinical characteristics of the 25 detected and the eight undetected cases with available medical records were evaluated in this study. Conclusions. Alternative surveillance proved effective, was complementary to the NYC DOH surveillance efforts, and increased the number of pediatric TB cases identified during the study period by 21%.

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