Hydranencephaly

Alistair G.S. Philip

doi:10.1542/peds.56.4.616b

Hydranencephaly

PEDIATRICS ◽

10.1542/peds.56.4.616b ◽

1975 ◽

Vol 56 (4) ◽

pp. 616-617

Author(s):

Alistair G.S. Philip

Keyword(s):

Clinical Evidence ◽

Venous Blood ◽

Capillary Blood

The article by Koffler and colleagues presented an interesting hypothesis attributing hydranencephaly to elevated hematocrit levels in a newborn. The hypothesis is quite reasonable, but appears to be based on shaky clinical evidence. The authors make it clear that their determinations of hematocrit levels were made on capillary blood, but do not make it clear how they were obtained. Their statements about polycythemia and hyperviscosity relate to venous blood. Since no studies of viscosity were performed, it may not be justifiable to assume that because the capillary hematocrit was greatly elevated, hyperviscosity was present.

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Comparison of capillary, venous and buffy coat blood samples in detecting Plasmodium species among malaria suspected patients attending at Hamusite health center. A cross-sectional study

BMC Infectious Diseases ◽

10.1186/s12879-021-06290-6 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Getu Abeje ◽

Woyneshet Gelaye ◽

Getaneh Alemu

Keyword(s):

Health Center ◽

Detection Rate ◽

Venous Blood ◽

Cross Sectional Study ◽

Buffy Coat ◽

Blood Film ◽

Capillary Blood ◽

Sectional Study ◽

Cross Sectional ◽

Blood Samples

Abstract Background Both capillary and venous blood samples have been interchangeably used for the diagnosis of malaria in Ethiopia. However, Plasmodium parasites are thought to be more concentrated in capillary than in venous blood. Hence, selecting a sample source where parasites are more concentrated is indispensable approach in order to maximize the accuracy of blood film microscopy. Therefore, the present study aimed to compare the detection rate and the parasitemia level of Plasmodium species from conventional capillary and venous blood films, and buffy coat preparations. Methods A facility based cross-sectional study was conducted from Feburary to March 2020 among 210 febrile patients attending Hamusite health center, northwest Ethiopia. Capillary and venous blood samples were collected and buffy coat was prepared from each sample. Thin and thick blood films were prepared, stained, and examined microscopically following standard protocol. Data were analysed using Statistical Package for Social Sciences Software version 20 and Med-Calc software version 19.3. Results Capillary blood buffy coat (61/210, 29.0%) had significantly higher detection rate as compared to capillary (48/210, 22.9%) and venous (42/210, 20.0%) blood films (p < 0.001). However, no significant difference was observed between capillary and venous blood films (p = 0.070) in detecting Plasmodium species. The highest and the lowest mean asexual stage parasite counts were found in capillary blood buffy coat (4692.88) and venous blood (631.43) films, respectively showing significant variations (p < 0.001). Mean gametocyte count was also highest in capillary blood buffy coat (3958.44). As compared to capillary blood buffy coat, the sensitivity of venous blood buffy coat, capillary blood film and venous blood film were 73.8, 78.7, 68.9%, respectively. Conclusion Capillary blood buffy coat samples showed the highest sensitivity in detecting and quantitating malaria parasites that its use should be promoted in clinical settings. However, conventional capillary and venous blood films could be used interchangeably.

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Effects of Different Methods Used to Take Blood Samples on Blood Glucose Measurements

Clinical Nursing Research ◽

10.1177/10547738211024782 ◽

2021 ◽

pp. 105477382110247

Author(s):

Eda Ergin ◽

Ayten Zaybak

Keyword(s):

Blood Glucose ◽

Glucose Tolerance Test ◽

Venous Blood ◽

Tolerance Test ◽

Capillary Blood ◽

Oral Glucose ◽

Blood Samples ◽

Significant Difference ◽

Measurement Results ◽

Quasi Experimental

The purpose of this study is to compare whether or not there is a difference between venous and capillary blood samples in blood glucose measurements and investigate the effects of different aseptic methods used in skin cleaning before collecting blood samples on measurement results. This quasi-experimental study was conducted with 109 patients. The capillary first and second blood drop values taken from the patients after fasting and at 2 hours following 75 g oral glucose tolerance test (OGTT) and capillary and venous blood glucose values were compared. There was no significant difference between the median venous blood glucose value and the capillary second blood drop value taken after wiping the finger with alcohol. There was no significant difference between the first and second blood drop values of capillary blood glucose 2 hours after OGTT.

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Blood Glucose Assay Using Dextrostix and a Reflectance Meter

Annals of Clinical Biochemistry International Journal of Laboratory Medicine ◽

10.1177/000456327200900144 ◽

1972 ◽

Vol 9 (1-6) ◽

pp. 91-94 ◽

Cited By ~ 6

Author(s):

I. W. Percy-Robb ◽

R. S. McMaster ◽

A. D. B. Harrower ◽

L. J. P. Duncan

Keyword(s):

Blood Glucose ◽

Venous Blood ◽

Reference Method ◽

Capillary Blood ◽

Blood Samples ◽

Laboratory Staff ◽

Glucose Assay ◽

Reflectance Meter ◽

High Degree ◽

Blood Glucose Concentrations

The ‘Dextrostix’-reflectance meter system for blood glucose analysis has been evaluated using a blood glucose reference method. A high degree of concordance between the two methods was obtained when analyses were performed by skilled laboratory staff on venous blood samples containing fluoride, with a 75 s contact time. Skilled laboratory staff performed significantly better than unskilled staff. Capillary blood glucose concentrations correlated poorly with concentrations in venous blood samples taken at the same time as the capillary blood.

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CAPILLARY BLOOD VERSUS ARTERIAL OR VENOUS BLOOD FOR TACROLIMUS MONITORING IN LIVER TRANSPLANTATION

Transplantation Journal ◽

10.1097/00007890-199509000-00020 ◽

1995 ◽

Vol 60 (5) ◽

pp. 512-514 ◽

Cited By ~ 4

Author(s):

ASHOK B. JAIN ◽

ANTONIO PINNA ◽

JOHN J. FUNG ◽

VIJAY WARTY ◽

AJAY K. SINGHAL ◽

...

Keyword(s):

Liver Transplantation ◽

Venous Blood ◽

Capillary Blood

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An Anti-Nucleocapsid Antigen Sars-Cov-2 Total Antibody Assay Finds Comparable Results in Edta-Anticoagulated Whole Blood Obtained from Capillary and Venous Blood Sampling

Data ◽

10.3390/data5040105 ◽

2020 ◽

Vol 5 (4) ◽

pp. 105

Author(s):

Martin Risch ◽

Marc Kovac ◽

Corina Risch ◽

Dorothea Hillmann ◽

Michael Ritzler ◽

...

Keyword(s):

Whole Blood ◽

Venous Blood ◽

Capillary Blood ◽

Blood Sampling ◽

Attractive Alternative ◽

Antibody Assay ◽

Antibody Assays ◽

Antibody Titers ◽

Antibody Levels ◽

Venous Blood Sampling

Although SARS-CoV-2 antibody assays have been found to provide valid results in EDTA-anticoagulated whole blood, so far, they have not demonstrated that antibody levels in whole blood originating from capillary blood samples are comparable to antibody levels measured in blood from a venous origin. Here, blood is drawn simultaneously by capillary and venous blood sampling. Antibody titers are determined by an assay employing electrochemiluminescence (ECLIA) and SARS-CoV-2 total immunoglobulins are detected with specificity directed against the nucleocapsid antigen. Six individuals with confirmed COVID-19 and six individuals without COVID-19 are analyzed. Antibody titers in capillary venous whole blood did not show significant differences, and when corrected for hematocrit, they did not differ from the results obtained from serum. In conclusion, capillary sampled EDTA-anticoagulated whole blood seems to be an attractive alternative matrix for the evaluation of SARS-CoV-2 antibodies when employing ECLIA for detecting total antibodies directed against nucleocapsid antibodies.

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Comparison of capillary and venous blood for malaria detection using two PCR based assays in febrile patients in Sierra Leone.

10.21203/rs.2.22092/v2 ◽

2020 ◽

Author(s):

Tomasz Leski ◽

Chris Rowe Taitt ◽

Umaru Bangura ◽

Joseph Lahai ◽

Joseph M. Lamin ◽

...

Keyword(s):

Sierra Leone ◽

Venous Blood ◽

Capillary Blood ◽

Clinical Samples ◽

Published Data ◽

Health Control ◽

Multiplexed Pcr ◽

Parasite Detection ◽

Diagnostic Technologies ◽

Clinical Case Management

Abstract Background. Malaria parasites infect over 200 million people and cause more than 400,000 deaths each year. Rapid and sensitive diagnostics are critical tools for clinical case management and public health control efforts. Both capillary and venous blood are currently used for malaria detection and while diagnostic technologies may not be equally sensitive with both materials, the published data on this subject are scarce and not conclusive.Methods. Paired clinical samples of venous and capillary blood from 141 febrile individuals in Bo, Sierra Leone, were obtained between January and May 2019 and tested for the presence of Plasmodium parasites using two multiplexed PCR assays: the FilmArray-based Global Fever Panel (GFP) and the TaqMan-based Malaria Multiplex Sample Ready (MMSR) assay.Results. We observed no significant differences in Plasmodium parasite detection between capillary and venous blood for both assays. The GFP assay was more sensitive than MMSR for all markers that could be compared (Plasmodium spp. and P. falciparum) in both venous and capillary blood.Conclusions. No difference was found in malaria detection between venous and capillary blood using two different PCR-based detection assays. This data gives support for use of capillary blood, a material which can be obtained easier by less invasive methods, for PCR-based malaria diagnostics, independent of the platform.

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Comparison of Oseltamivir and Oseltamivir Carboxylate Concentrations in Venous Plasma, Venous Blood, and Capillary Blood in Healthy Volunteers

Antimicrobial Agents and Chemotherapy ◽

10.1128/aac.02408-12 ◽

2013 ◽

Vol 57 (6) ◽

pp. 2858-2862 ◽

Cited By ~ 6

Author(s):

Insti Instiaty ◽

Niklas Lindegardh ◽

Podjanee Jittmala ◽

Warunee Hanpithakpong ◽

Daniel Blessborn ◽

...

Keyword(s):

Healthy Volunteers ◽

Venous Blood ◽

Capillary Blood ◽

Time Dependent ◽

Oseltamivir Carboxylate ◽

Venous Plasma

ABSTRACTOseltamivir and oseltamivir carboxylate concentrations were measured in venous plasma, venous blood, and capillary blood taken simultaneously from 24 healthy volunteers. Median (range) venous-blood-to-plasma ratios were 1.42 (0.920 to 1.97) for oseltamivir and 0.673 (0.564 to 0.814) for oseltamivir carboxylate. Capillary blood/venous plasma ratios were 1.32 (0.737 to 3.16) for oseltamivir and 0.685 (0.502 to 1.34) for oseltamivir carboxylate. Oseltamivir concentrations in venous and capillary blood were similar. Oseltamivir carboxylate showed a time-dependent distribution between venous and capillary blood.

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Ferritin concentrations in plasma from capillary (finger prick) blood and venous blood compared.

Clinical Chemistry ◽

10.1093/clinchem/29.5.871 ◽

1983 ◽

Vol 29 (5) ◽

pp. 871-873 ◽

Cited By ~ 8

Author(s):

L A Mejía ◽

F E Viteri

Keyword(s):

Blood Plasma ◽

Close Association ◽

Venous Blood ◽

Capillary Blood ◽

Ferritin Concentration ◽

Antecubital Vein ◽

Finger Prick ◽

Adults And Children ◽

Venous Plasma

Abstract Investigating the feasibility and validity of determining plasma ferritin concentration in blood obtained by finger prick, we studied 29 adults (ages 21-49 years) and 35 children (ages 14-66 months). Blood was sampled simultaneously in the same subject from both the antecubital vein (venous blood) and by finger pricking (capillary blood). The plasma was obtained by centrifugation. Ferritin concentration was determined by immunoradiometric analysis. Ferritin concentration in plasma from capillary blood was significantly higher than in venous plasma (p less than 0.01). This difference was more marked in children. The correlation between ferritin from the two blood sources was highly significant (r2 = 0.945 and 0.994 for samples from adults and children, respectively), and the slopes of the respective regression lines in both children and adults were significantly different from 1 (p less than 0.0001). We conclude that, despite the close association between the two procedures, the determination of ferritin concentration in capillary blood plasma overestimates the concentration of ferritin in venous blood plasma.

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