More on Taurine

PEDIATRICS ◽  
1989 ◽  
Vol 83 (6) ◽  
pp. 1072-1073
Author(s):  
JON E. TYSON ◽  
CHARLES MIZE ◽  
ROBERT LASKY
Keyword(s):  
Randomized Trial ◽  
Selection Bias ◽  
Statistical Analyses ◽  
Careful Selection ◽  
Specific Question ◽  
Taurine Supplementation ◽  
Recent Commentary ◽  
Methodologic Problem ◽  
Selection Of Patients ◽  
Selection Of

In a recent commentary, Perlman called for further study of the effects of taurine and expressed reservations about our randomized trial of taurine supplementation for infants weighing ≤1300 g at birth. We agree with the need for further investigation but would like to respond to his criticism that our sampling of patients was biased and that our statistical analyses were inappropriate. What Perlman contends is a methodologic problem and a selection bias is, in fact, the careful selection of patients for the specific question under investigation.

Endoscopic Treatment of Subglottic and Tracheal Stenosis by Radial Laser Incision and Dilation

1987 ◽  
Vol 96 (6) ◽  
pp. 661-664 ◽  
Author(s):  
Stanley M. Shapshay ◽  
Roger L. Hybels ◽  
John F. Beamis ◽  
R. Kirk Bohigian
Keyword(s):  
Carbon Dioxide ◽  
Tracheal Stenosis ◽  
Endoscopic Treatment ◽  
Mechanical Trauma ◽  
Careful Selection ◽  
Tracheal Collapse ◽  
Laser Incision ◽  
Selection Of Patients ◽  
Selection Of

Five patients with severe fibrous subglottic and tracheal stenosis were treated by endoscopic radial laser incision and dilation using both carbon dioxide and neodymium:yttrium aluminum garnet lasers. Good results were noted without complications in all patients in a follow-up period of at least 1 year. Careful selection of patients, excluding those with tracheal collapse or tracheomalacia, and preservation of tracheal epithelium with minimal heat and mechanical trauma are considered essential for good results.

Subtotal laryngectomy with myomucosal shunt

1989 ◽  
Vol 103 (5) ◽  
pp. 504-507 ◽  
Author(s):  
H. R. Chandrachud ◽  
M. K. Chaurasia ◽  
K. P. Sinha
Keyword(s):  
Squamous Cell Carcinoma ◽  
Frozen Section ◽  
Careful Selection ◽  
Voice Production ◽  
Tracheal Stoma ◽  
The Voice ◽  
Selection Of Patients ◽  
Thyroarytenoid Muscle ◽  
Tumour Extent ◽  
Selection Of

AbstractThis is a modified subtotal laryngectomy. On the tumour-free side of the larynx, some posterior structures, with their neurovascular supply are preserved. The endolaryngeal mucosa is tubed in continuity with the trachea below and projects into the pharynx above. Thus a myomucosal shunt is formed. Air is directed into it by finger occlusion of the tracheal stoma.The voice production is highly satisfactory. Aspiration is prevented by constriction of the thyroarytenoid muscle which provides a valved upper end of the tube.The possibility of leaving tumour in the laryngeal remnant is eliminated by careful selection of patients, and re-confirmation of tumour extent intra-operatively and a frozen section.Eleven such operations have been performed since October 1983 for squamous cell carcinoma, some previously irradiated. None of the patients had local recurrence. Only one had an aspiration problem which later resolved. All acquired a satisfactory voice

scholarly journals Results of arthroscopic meniscal repair

2017 ◽  
Vol 5 (1_suppl) ◽  
pp. 2325967117S0001
Author(s):  
María Belén Orlowski ◽  
Damián Arroquy ◽  
Jorge Chahla ◽  
Jorge Guiñazú ◽  
Martín Carboni Bisso ◽  
...  
Keyword(s):  
Success Rate ◽  
Acl Reconstruction ◽  
Failure Rate ◽  
Clinical Success ◽  
Intraoperative Complications ◽  
Meniscal Repair ◽  
Careful Selection ◽  
Meniscal Suture ◽  
Selection Of Patients ◽  
Selection Of

Objectives: Currently the arthroscopic treatment of meniscal pathology has become one of the most common procedures in orthopedic practice and although in most cases meniscectomy is done, meniscal sutures are the treatment of choice when a reparable lesion is diagnosed, especially in young patients. It has been reported that the meniscal repair leads to a lower incidence of developing degenerative changes in the long-term when compared with meniscectomy and nonsurgical treatment of meniscal injuries. The aim of this study was to determine the success rate of meniscal repair achieved in our sports medicine practice. Methods: Between 2006 and 2015, 62 meniscal tears in 58 patients with a mean age of 31 years (range 15-58) were repaired. Mean follow-up was 52 months (range 6-120 months). In 16 patients (28%) was associated with arthroscopic ACL reconstruction. The repair techniques used included outside-in sutures, inside-out sutures, all-inside sutures and a combination of techniques. Failure of the repair was defined by the requirement for repeat knee arthroscopy and partial or subtotal meniscectomy. The indication of arthroscopic revision was based on the presence of mechanical symptoms, after the suture. Results: Failure of meniscus repair occurred in four patients (failure rate: 6.45%), one case was associated with ACL reconstruction (failure rate: 6.25%) and 3 had undergone isolated meniscal suture (failure rate: 8%). The average time for the reoperation was 15 months (4-24). We had no intraoperative complications. Conclusion: The reported failure rate of meniscal repair in stable knees varies between 12% and 43%, with reports that demonstrate a clinical success rate of 100%. In this study, we obtained a success rate of 93.5%. These results are slightly higher than those in the literature, which can be attributed to careful selection of patients and the fact that clinical success tends to be better than the assessed arthroscopically. In summary, we consider the meniscal repair as a successful option in the treatment of meniscal rupture. Due to the importance it has recovered in the last time preserving the meniscus, in the future we should greatly increase our rate of meniscal suture. We hold that careful selection of patients and the type of injury to repair, optimizes the success of meniscal repairs.

scholarly journals Combined Liver and Multivisceral Resections

HPB Surgery ◽  
2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Martin de Santibañes ◽  
Agustin Dietrich ◽  
Eduardo de Santibañes
Keyword(s):  
Liver Metastases ◽  
Postoperative Morbidity ◽  
Scientific Evidence ◽  
Mortality Rates ◽  
Careful Selection ◽  
Colorectal Tumors ◽  
Extensive Experience ◽  
Electronic Search ◽  
Selection Of Patients ◽  
Selection Of

Background. Combined liver and multivisceral resections are infrequent procedures, which demand extensive experience and considerable surgical skills. Methods. An electronic search of literature related to this topic published before June 2013 was performed. Results. There is limited scientific evidence of the feasibility and clinical outcomes of these complex procedures. The majority of these cases are simultaneous resections of colorectal tumors with liver metastases. Combined liver and multivisceral resections can be performed with acceptable postoperative morbidity and mortality rates only in carefully selected patients. Conclusion. Lack of experience in these aggressive surgeries justifies a careful selection of patients, considering their comorbidities.

scholarly journals Multidrug-resistant Gram-negative bacteria-resistant infections: epidemiology, clinical issues and therapeutic options

2016 ◽  
Vol 10 (4) ◽  
pp. 364 ◽  
Author(s):  
Matteo Bassetti ◽  
Davide Pecori ◽  
Maddalena Peghin
Keyword(s):  
Risk Factors ◽  
Multidrug Resistant ◽  
Therapeutic Options ◽  
Gram Negative Bacteria ◽  
Careful Selection ◽  
Clinical Issues ◽  
Gram Negative ◽  
Severe Infections ◽  
Selection Of Patients ◽  
Selection Of

In the last decade, we have witnessed a dramatic increase in the number of multidrug resistant Gram-negative (MDRGN) bacterial pathogens, both in Italy and worldwide, with Enterobacteriacae (mostly Klebsiella pneumoniae), Pseudomonas aeruginosa and Acinetobacter baumannii being the major threats in clinical practice. Inadequate empirical antimicrobial therapy of severe infections caused by MDR Enterobacteriacae has been associated with an increased morbidity and mortality. However, a careful selection of patients who may receive empirical treatment covering MDR Enterobacteriacae is important to avoid the overuse of broad-spectrum antibiotics. The aim of this review is to describe the mechanism of resistance, epidemiology, risk factors, clinical issues, and therapeutic options for MDRGN pathogens.

Safely Precautions for Bronchoscopic CO2 Laser Surgery

1986 ◽  
Vol 95 (2) ◽  
pp. 242-244 ◽  
Author(s):  
James A. Duncavage ◽  
Robert H. Ossoff
Keyword(s):  
Co2 Laser ◽  
Laser Surgery ◽  
Tracheobronchial Tree ◽  
Careful Selection ◽  
Tumor Vascularity ◽  
X Ray ◽  
Malignant Lesions ◽  
Selection Of Patients ◽  
Selection Of ◽  
Special Instrumentation

Certain safety precautions are necessary in the performance of CO2 laser bronchoscopy. These include special instrumentation and careful selection of patients. Assessment of tumor vascularity is mandatory because of the limited hemostasis provided by the CO2 laser. The x-ray film evaluation of the integrity of the tracheobronchial tree—for treatment that involves the palliation of obstructing malignant lesions—is outlined.

scholarly journals Benzodiazepines for anxiety disorders: maximising the benefits and minimising the risks

2012 ◽  
Vol 18 (4) ◽  
pp. 250-258 ◽  
Author(s):  
Vladan Starcevic
Keyword(s):  
Side Effects ◽  
Anxiety Disorders ◽  
Therapeutic Use ◽  
Withdrawal Symptoms ◽  
Psychological Interventions ◽  
Careful Selection ◽  
Beneficial Use ◽  
Selection Of Patients ◽  
Selection Of

SummaryBenzodiazepines still play an important role in the management of anxiety disorders but dependence is associated with their therapeutic use. The key to effective and safe long-term use of benzodiazepines is: the careful selection of patients who might benefit from them; administration in clinical situations in which they are more likely to be beneficial; use of lower doses and in conjunction with an antidepressant, if possible; monitoring and managing their side-effects; and minimising the risk of withdrawal symptoms and relapse, mainly through tapering the dose and/or combining with effective psychological interventions.

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