Tongue-tie: Management of a Short Sublingual Frenulum

1995 ◽  
Vol 16 (9) ◽  
pp. 345-346
Author(s):  
Paul A. Levy
Keyword(s):  
Cell Death ◽  
Early Development ◽  
Initial Attachment ◽  
Floor Of The Mouth ◽  
15Th Century ◽  
Speech Defects

Tongue-tie, or ankyloglossia, historically has been believed to cause speech defects, as well as breastfeeding difficulties and dental problems. St. Mark wrote, "The string of his tongue was loosed and he spoke plain," and midwives in the 15th century reportedly kept a fingernail sharp to cut the frenula of all newborns in an attempt to prevent possible speech problems. Only within the last century has it become acceptable not to perform frenulotomy for children who have ankyloglossia. During early development the tongue is fused to the floor of the mouth. Cell death and resorption free the tongue, with the frenulum left as the only remnant of the initial attachment.

The early development of antenna and antennal sensilla in the noctuid moth, Agrotis segetum (Insecta: Lepidoptera)

1990 ◽  
Vol 48 (3) ◽  
pp. 502-503
Author(s):  
Eric Hallberg ◽  
Lina Hansén
Keyword(s):  
Cell Death ◽  
Stem Cell ◽  
Early Development ◽  
Larval Stage ◽  
Pupal Stage ◽  
Agrotis Segetum ◽  
Antennal Sensilla ◽  
Noctuid Moth ◽  
Standard Procedures

The antennal rudiments in lepidopterous insects are present as disks during the larval stage. The tubular double-walled antennal disk is present beneath the larval antenna, and its inner layer gives rise to the adult antenna during the pupal stage. The sensilla develop from a cluster of cells that are derived from one stem cell, which gives rise to both sensory and enveloping cells. During the morphogenesis of the sensillum these cells undergo major transformations, including cell death. In the moth Agrotis segetum the pupal stage lasts about 14 days (temperature, 25°C). The antennae, clearly seen from the exterior, were dissected and fixed according to standard procedures (3 % glutaraldehyde in 0.15 M cacaodylate buffer, followed by 1 % osmiumtetroxide in the same buffer). Pupae from day 1 to day 8, of both sexes were studied.

Region of caspase-3 activation and programmed cell death in the early development of the mouse forebrain

2003 ◽  
Vol 145 (2) ◽  
pp. 241-248 ◽  
Author(s):  
Koko Urase ◽  
Yoriko Kouroku ◽  
Eriko Fujita ◽  
Takashi Momoi
Keyword(s):  
Cell Death ◽  
Programmed Cell Death ◽  
Early Development ◽  
Caspase 3

scholarly journals Through the Cowgate: life in 15th-century Edinburgh as revealed by excavations at St Patrick's Church

2011 ◽  
Vol 42 ◽  
Author(s):  
Elizabeth Jones ◽  
Anne Crone ◽  
Morag Cross ◽  
Julie Franlin ◽  
Sarah-Jane Haston ◽  
...  
Keyword(s):  
Early Development ◽  
Flash Floods ◽  
Dung Beetles ◽  
14Th Century ◽  
15Th Century ◽  
High Street ◽  
Rubbish Dump ◽  
The Town

Excavations in the grounds of St Patrick's Church, Edinburgh were undertaken by Headland Archaeology from November 2006 to February 2007 on behalf of the Archdiocese of St Andrews and Edinburgh in advance of the construction of a hotel on the site. Soil analyses suggested that flash floods had swept through this part of Cowgate up until the early development of the medieval town upslope in the 11th-12th centuries. This early pattern was followed by the gradual build-up of material washed downslope from the High Street; this contained midden material and dung beetles, illustrating the nearby presence of the town. The site lay outwith the bounds of the burgh until the 14th century, when a substantial ditch was cut across the site, believed to be the medieval town boundary. The ditch was backfilled in the 15th century and finds and samples have revealed a vivid picture of life in the medieval town. The ditch was a stinking rubbish dump for many kinds of human and animal detritus, which illustrates that the Cowgate was a busy thoroughfare to the town's markets and contained a variety of industries, including horn working. After the ditch was filled in deep midden deposits, characteristic of this area of Edinburgh, built up on the site.

Cell death in the ventral region of the neural retina during the early development of the chick embryo eye

1988 ◽  
Vol 222 (3) ◽  
pp. 272-281 ◽  
Author(s):  
Gervasio Martín-Partido ◽  
Lucía Rodríguez-Gallaro ◽  
Ignacio S. Alvarez ◽  
Julio Navascués
Keyword(s):  
Cell Death ◽  
Chick Embryo ◽  
Early Development ◽  
Neural Retina ◽  
Ventral Region

scholarly journals The Hindu-Muslim Interdependence: A Study of Balinese Local Wisdom

2020 ◽  
Vol 28 (2) ◽  
pp. 195-218
Author(s):  
Fajri Zulia Ramdhani ◽  
Busro Busro ◽  
Abdul Wasik
Keyword(s):  
Early Development ◽  
Religious Communities ◽  
Muslim Community ◽  
Religious Activities ◽  
15Th Century ◽  
Muslim Communities ◽  
The Relationship

Muslim communities in the Hindu-majority area of Bali have existed since the 15th century. Since that period, the interdependence between the two religious communities has been something inevitable. This study aims to enrich the treasures of the interdependence discourse that exists between Muslims and Hindus in Bali. It tries to trace the history and early development of Islam in Bali, the relation pattern between Muslims and Hindus, and local wisdom influencing the interdependence in Bali. Data for this study were obtained through observations and interviews with key figures in Klungkung, Bali. After profound analysis, the writer concludes that the emergence of Islam in Bali occurred when Dalem Ketut Ngelesir (1380-1460) visited Majapahit during the vassal royal conference in early 1380 and brought 40 Muslim escorts. This period also marked the early Hindus-Muslim relationship in Bali with Klungkung as the first area with the Muslim community. Later, the relationship between Hindus and Muslims was maintained in the four consecutive periods: kingdom, colonization, post-independence, and the present. Among the local wisdom that has influenced the interdependence and integration between the two religious communities are megibung, ngejot, and religious activities such as the birth of Prophet Muhammad SAW., Nyepi, odalan, takbiran, and Eid al-Fitr.

The early development of the sheep trophoblast and the involvement of cell death

1985 ◽  
Vol 174 (4) ◽  
pp. 471-488 ◽  
Author(s):  
J. A. Carnegie ◽  
M. E. McCully ◽  
H. A. Robertson
Keyword(s):  
Cell Death ◽  
Early Development

Patterns of Epithelial Cell Death during Early Development of the Human Inner Ear

1990 ◽  
Vol 99 (6) ◽  
pp. 482-488 ◽  
Author(s):  
Juan J. Represa ◽  
Jose A. Moro ◽  
Francisco Pastor ◽  
Angel Gato ◽  
Enrique Barbosa
Keyword(s):  
Cell Death ◽  
Epithelial Cell ◽  
Inner Ear ◽  
Early Development ◽  
Human Inner Ear ◽  
Epithelial Cell Death

Mesodermal Cell Deaths during the Early Development of the Scleral Bones in the Chick

1956 ◽  
Vol s3-97 (39) ◽  
pp. 355-368
Author(s):  
L. J. HALE
Keyword(s):  
Cell Death ◽  
Early Development ◽  
Normal Position ◽  
Mesodermal Cell ◽  
Osteogenic Cells ◽  
Cell Destruction

1. The positions of degenerating cells in the mesenchyme of the scleral bone primordia of the chick, and in the fibrous sclera beneath them, have been ascertained. 2. It is shown that the number of cell deaths within the bone primordia, and also beneath them in the fibrous sclera, is markedly higher than, and follows a different pattern from the regions between. 3. A centre of cell destruction is seen to occur at and near to the boundary of the mesenchyme and fibrous sclera. This begins in 7- to 8-day primordia, rises to a peak at 8 to 9 days, and subsides in 9- to 10-day primordia. 4. A second centre of cell death occurs in the mesenchyme nearer to the conjunctival papilla. It starts in 8- to 9-day eyes about mid-way between the conjunctiva and sclera, and as it increases in intensity, the centre moves nearer to the conjunctival papilla (9 to 10 days), beneath which it appears to subside (some 10-day primordia). 5. The function of these waves of cell destruction is discussed. It is concluded that their most likely function is morphogenetic; they may make a space into which the osteogenic cells migrate, or they may ensure a normal position and shape for the developing bone. Consideration has also been given to the possibility that the products of cell death might have a histiogenetic function.

Individual differences, social attention, and the history of the social motivation hypotheses of autism

2019 ◽  
Vol 42 ◽  
Author(s):  
Peter C. Mundy
Keyword(s):  
Individual Differences ◽  
Early Development ◽  
Emotional Development ◽  
Social Motivation ◽  
Social Attention ◽  
Social Emotional Development ◽  
Social Emotional ◽  
Precise Understanding ◽  
The Social ◽  
History Of

Abstract The stereotype of people with autism as unresponsive or uninterested in other people was prominent in the 1980s. However, this view of autism has steadily given way to recognition of important individual differences in the social-emotional development of affected people and a more precise understanding of the possible role social motivation has in their early development.

Classical social reward signatures in infants with later ASD

2019 ◽  
Vol 42 ◽  
Author(s):  
Teodora Gliga ◽  
Mayada Elsabbagh
Keyword(s):  
Early Development ◽  
Social Motivation ◽  
Self Report ◽  
Social Reward ◽  
Socially Motivated

Abstract Autistic individuals can be socially motivated. We disagree with the idea that self-report is sufficient to understand their social drive. Instead, we underscore evidence for typical non-verbal signatures of social reward during the early development of autistic individuals. Instead of focusing on whether or not social motivation is typical, research should investigate the factors that modulate social drives.

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