Fabrication of Ring-shaped Bioactuator Powered by Cardiomyocytes
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AbstractWe have proposed a novel use of pulsating living cells as a driving source for a micro bio-actuator. Cardiyomyocytes contract autonomously using chemical energy. But, contractile force of a single cardiomyocyte is not enough to actuate a micro robot or a mechanical system. So it is necessary to reconstruct cardiomyocytes to increase the ability to contract. We focused on the reconstruction of cardiomyocytes using a basement membrane protein mixture. In this paper, we fabricated a prototype cardiomyocyte gel structure. We confirmed that the ring-shaped cardiomyocyte gel structure condensed around the central cylinder within the PDMS mold and contracted synchronously and autonomously.
1998 ◽
Vol 5
(1)
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pp. 80A-80A
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1982 ◽
Vol 118
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pp. 971
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1988 ◽
Vol 85
(9)
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pp. 2919-2923
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1996 ◽
Vol 270
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pp. C1743-C1750
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1989 ◽
Vol 8
(1)
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pp. 65-72
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