scholarly journals Recurrent perichondritis as a debut «mask» of acute lymphoblastic leukemia in a young child (clinical case)

2019 ◽  
pp. 83-88
Author(s):  
N.G. Chumachenko ◽  
◽  
T.L. Marushko ◽  
O.V. Golovchenko ◽  
V.N. Fisun ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Young Child ◽  
Clinical Case ◽  
Lymphoblastic Leukemia

Intrathecal Chemotherapy-Related Myeloencephalopathy in a Young Child with Acute Lymphoblastic Leukemia

1995 ◽  
Vol 12 (4) ◽  
pp. 377-385 ◽  
Author(s):  
Jesús García-Tena ◽  
Juan A. López-Andreu ◽  
Josep Ferrís ◽  
Francisco Menor ◽  
Fernando Mulas ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Young Child ◽  
Lymphoblastic Leukemia ◽  
Intrathecal Chemotherapy

A Case of Anterior Uveitis in the Presence of Acute Lymphoblastic Leukemia

2020 ◽  
pp. 50-53
Author(s):  
A.V. Kolesnikov ◽  
◽  
I.V. Kirsanova ◽  
N.S. Tumanova ◽  
M.M. Averina ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Clinical Case ◽  
Complete Blood Count ◽  
Lymphoblastic Leukemia ◽  
Underlying Disease ◽  
Pathological Process ◽  
The Body ◽  
Cervical Lymph Nodes ◽  
Antiinflammatory Therapy ◽  
Ocular Manifestations

A clinical case of the development of a rare form of ocular manifestation of acute lymphoblastic leukemia, one of the most common oncological diseases in childhood, is described. A seven-year-old child initially had weakness, decreased appetite, and a single episode of subfebrile condition for two days without catarrhal symptoms. Further, an increase in the cervical lymph nodes was noticed. Then a hemorrhagic rash appeared all over the body. In the complete blood count (CBC) test: erythrocytes (RBC) – 3.8 * 1012 / l, hemoglobin (HGB) – 115 g/L, leukocytes (WBC) – 121*109/L, platelets (PLT) – 22*109/L. The child was admitted to the regional children’s clinical hospital. On examination, 90% of blast cells were detected in the myelogram. Against the background of a confirmed remission of the oncological disease, iridocyclitis of the left eye was diagnosed. It could not be stopped by standard antibacterial and antiinflammatory therapy. After a while, the right eye was also involved in the pathological process. Hematologists confirmed the recurrence of acute lymphoblastic leukemia after bone marrow puncture. The presented clinical case demonstrates the fact that the treatment of ocular manifestations of acute lymphoblastic leukemia can be effective only in the treatment of the underlying disease.

Parents’ Experiences of Having a Young Child With Acute Lymphoblastic Leukemia in China

2020 ◽  
pp. 104345422097546
Author(s):  
Qian Liu ◽  
Marcia A. Petrini ◽  
Dan Luo ◽  
Bing Xiang Yang ◽  
Jiong Yang ◽  
...  
Keyword(s):  
Health Care ◽  
Acute Lymphoblastic Leukemia ◽  
Young Child ◽  
Health Care Professionals ◽  
Financial Burden ◽  
Lymphoblastic Leukemia ◽  
Community Support ◽  
Central China ◽  
Parental Experiences ◽  
Parents Experiences

Background: Understanding parents’ experiences is a prerequisite to developing interventions that are sensitive to needs of children and families. In China, little is known about parental experiences of having a young child with acute lymphoblastic leukemia (ALL). This phenomenological study aimed to describe parental experiences of having a young child with ALL in China. Method: Ten parents, recruited in central China using purposive sampling, participated in face-to-face, in-depth interviews using Haase’s adaptation of Colaizzi’s phenomenological method. Results: Five theme categories were identified: (a) The Cancer Diagnosis as a Terrible Disaster—The Sky is Falling, (b) Fighting the Beast, (c) Putting on a Happy Face and Other Coping Strategies, (d) Diagnosis Disclosure: If We Tell and How to Tell, and (e) Hope-Filled Expectations: Returning to Normal Life. Conclusion: Parents put their child’s health as their top priority. They strive to manage uncertainty about prognosis and cope with enormous pressures caused by children’s suffering, financial burden, and stigma. Parents also express their resilience and hope throughout their child’s cancer journey. Support services to strengthen specific families’ protective factors (i.e., family/community support, hope, and positive coping) are needed to foster resilience and quality of life. Health care professionals should systematically assess parents’ needs, provide validated education materials, and implement tailored interventions across the cancer continuum. Public education and advocacy about cancer is also necessary to decrease cancer-related stigma, and provide financial aid and health care resources in pediatric oncology.

scholarly journals Diagnosis and treatment of acute lymphoblastic leukemia in a patient with niimegen syndrome first diagnosed in adulthood

2020 ◽  
Vol 65 (1) ◽  
pp. 39-51
Author(s):  
K. I. Zarubina ◽  
E. N. Parovnikova ◽  
A. V. Kokhno ◽  
O. A. Gavrilina ◽  
V. V. Troitskaya ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
T Cell ◽  
Clinical Case ◽  
De Novo ◽  
Lymphoblastic Leukemia ◽  
Autosomal Recessive Disorder ◽  
Nijmegen Breakage Syndrome ◽  
Diagnosis And Treatment ◽  
Genetic Syndromes ◽  
Cell Acute Lymphoblastic Leukemia

Background. Nijmegen breakage syndrome is a rare hereditary autosomal recessive disorder characterized by microcephaly, combined primary immunodeficiency, sensitivity to radioactive radiation and liability to tumours of various nature (in particular, those developing in the lymphatic tissue). This syndrome is part of a group of diseases characterized by chromosomal instability. This disease develops as a result of mutations in the NBS1 gene, which is responsible for repairing DNA double-stranded breaks.Aim. To describe a clinical case of the diagnosis and treatment of T-cell acute lymphoblastic leukemia in a patient with Nijmegen syndrome, which was first diagnosed in adulthood.General findings. A clinical case of the diagnosis and treatment of Nijmegen syndrome in a young man with de novo T-cell acute lymphoblastic leukemia is presented. The difficulty of early diagnosis of hereditary genetic syndromes is demonstrated. The genetic character of such conditions is revealed over time, when children and young adults begin to develop long-term complications, in particular tumours of various origins. Early detection of hereditary genetic syndromes in children is of great importance.

Epidural Spinal Mass as the Presenting Feature of B-Acute Lymphoblastic Leukemia in a Young Child

2019 ◽  
Vol 42 (8) ◽  
pp. e845-e847
Author(s):  
Stacy Chapman ◽  
Jie Li ◽  
Muhamad Almiski ◽  
Hayley Moffat ◽  
Sara J. Israels
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Young Child ◽  
Lymphoblastic Leukemia

scholarly journals Клинический случай легочной формы мукормикоза у ребенка с острым лимфобластным лейкозом

2021 ◽  
Vol 2 (4) ◽  
pp. 38-47
Author(s):  
D. A. Kharagezov ◽  
Yu. N. Lazutin ◽  
E. A. Mirzoyan ◽  
A. G. Milakin ◽  
O. N. Stateshny ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Enzyme Immunoassay ◽  
Blood Count ◽  
Clinical Case ◽  
Lymphoblastic Leukemia ◽  
Underlying Disease ◽  
Main Diagnosis ◽  
X Ray ◽  
Pulmonary Mucormycosis ◽  
Stage Of Diagnosis

The article presents a clinical case of pulmonary mucormycosis in a 12‑year-old child at the stage of diagnosis of acute lymphoblastic leukemia. The first symptoms of the disease (headaches, malaise and weakness, pallor), changes in the general blood count (hyperleukocytosis up to 200 thousand cells/μl, single platelets). Based on the results of the examination, the main diagnosis was verified for acute lymphoblastic leukemia L2, IFT T-II, CD1a-. At the stage of diagnosis of acute lymphoblastic leukemia, the underlying disease was complicated by the development of right-sided pneumonia according to X-ray examination. To verify the etiology of infiltration of lung tissue, broncho-alveolar lavage was directed to microbiological diagnostics, which included studies: enzyme immunoassay, microscopic and cultural. On the aggregate of all the results obtained, invasive mucormycosis was diagnosed and antifungal therapy was started immediately.

scholarly journals TROMBOSIS OF MESENTERIAL VESSELS IN ACUTE LYMPHOBLASTIC LEUKEMIA (CASE REPORT)

2019 ◽  
Vol 72 (1) ◽  
pp. 133-136
Author(s):  
Veronika M. Dudnyk ◽  
Irina I. Andrikevych ◽  
Hennadiy M. Rudenko ◽  
Tetiana G. Korol ◽  
Kateryna V. Khromykh
Keyword(s):  
Case Report ◽  
Surgical Treatment ◽  
Acute Lymphoblastic Leukemia ◽  
Thrombolytic Therapy ◽  
Successful Treatment ◽  
Clinical Case ◽  
Lymphoblastic Leukemia ◽  
Diagnostic Problems ◽  
Mesenteric Vessels ◽  
Leukemia In Children

The article presents data on classification, diagnostic problems, treatment of acute lymphoblastic leukemia in children. Remaining unresolved problems of protocol chemotherapy complications of acute lymphoblastic leukemia. The presented clinical case of successful treatment of thrombosis of mesenteric vessels in a child with acute lymphoblastic leukemia, which included the stages of thrombolytic therapy and surgical treatment for resection of necrotized part of the ileum.

scholarly journals Clinical case of neonatal acute lymphoblastic leukemia

2019 ◽  
Vol 14 (5) ◽  
pp. 317-322
Author(s):  
N.S. Artiomova ◽  
S.M. Tsvirenko ◽  
V.I. Pokhylko ◽  
O.O. Kaliuzhka ◽  
S.I. Vernygora
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Clinical Case ◽  
Lymphoblastic Leukemia

scholarly journals Comparison of child and family reports of health-related quality of life in pediatric acute lymphoblastic leukemia patients after induction therapy

2020 ◽  
Author(s):  
Shohei Nakajima ◽  
Iori Sato ◽  
Takafumi Soejima ◽  
Katsuyoshi Koh ◽  
Motohiro Kato ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Acute Lymphoblastic Leukemia ◽  
Young Child ◽  
Lymphoblastic Leukemia ◽  
Health Related Quality ◽  
Proxy Reports ◽  
Self Reports ◽  
Related Quality ◽  
Health Related

Abstract Purposes: To determine the health-related quality of life (HRQOL) of children with acute lymphoblastic leukemia (ALL) during induction therapy, clarify the agreement between child self-reported and family proxy-reported HRQOL, and examine the related factors of HRQOL, especially child age, family attendance, and children’s social relationships outside of the family. Methods: We analyzed questionnaire data (2012–2017) from the Japanese Pediatric Leukemia/Lymphoma Study Group’s ALL-B12. Participants were children with B-cell Precursor ALL aged 5–18 and their families. Participants answered the Pediatric Quality of Life Inventory TM (PedsQL TM ) Generic Core Scales (PedsQL-G) and Cancer Module (PedsQL-C) to measure pediatric HRQOL. We calculated the differences between child self-reported and family proxy-reported subscale scores along with intraclass correlation coefficients (ICC). We conducted multiple regression analyses according to all participant pairs and age groups (young child, school age and adolescent), with ICCs for all PedsQL-G subscales (ICC-G) and all PedsQL-C subscales (ICC-C) as the outcome variables. Results: Five hundred twenty-two pairs of children and their families were analyzed. We observed a moderate level of agreement on most PedsQL subscales between the child self-reports and family proxy-reports; however, worry had the weakest agreement for all PedsQL subscales (ICC = .32). The agreement of ICC-C was positively related to family attendance for the young child group ( B = .185, p = .003). Conclusion: We observed some differences between child self-reports and family proxy-reports of HRQOL of children with ALL, suggesting that both parties should be administered HRQOL measurements during treatment.

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