scholarly journals Development of heart attack prediction model based on ensemble learning

2021 ◽  
Vol 4 (2(112)) ◽  
pp. 26-34
Author(s):  
Omar Shakir Hasan ◽  
Ibrahim Ahmed Saleh

With the advent of the data age, the continuous improvement and widespread application of medical information systems have led to an exponential growth of biomedical data, such as medical imaging, electronic medical records, biometric tags, and clinical records that have potential and essential research value. However, medical research based on statistical methods is limited by the class and size of the research community, so it cannot effectively perform data mining for large-scale medical information. At the same time, supervised machine learning techniques can effectively solve this problem. Heart attack is one of the most common diseases and one of the leading causes of death, so finding a system that can accurately and reliably predict early diagnosis is an essential and influential step in treating such diseases. Researchers have used various data mining and machine learning techniques to analyze medical data, helping professionals predict heart disease. This paper presents various features related to heart disease, and the model is based on ensemble learning. The proposed system involves preprocessing data, selecting attributes, and then using logistic regression algorithms as meta-classifiers to build the ensemble learning model. Furthermore, using machine learning algorithms (Support Vector Machines, Decision Tree, Random Forest, Extreme Gradient Boosting) for prediction on the Framingham Heart Study dataset and compared with the proposed methodology. The results show that the feasibility and effectiveness of the proposed prediction method based on group learning provide accuracy for medical recommendations and better accuracy than the single traditional machine learning algorithm.

Author(s):  
Baban. U. Rindhe ◽  
Nikita Ahire ◽  
Rupali Patil ◽  
Shweta Gagare ◽  
Manisha Darade

Heart-related diseases or Cardiovascular Diseases (CVDs) are the main reason for a huge number of death in the world over the last few decades and has emerged as the most life-threatening disease, not only in India but in the whole world. So, there is a need fora reliable, accurate, and feasible system to diagnose such diseases in time for proper treatment. Machine Learning algorithms and techniques have been applied to various medical datasets to automate the analysis of large and complex data. Many researchers, in recent times, have been using several machine learning techniques to help the health care industry and the professionals in the diagnosis of heart-related diseases. Heart is the next major organ comparing to the brain which has more priority in the Human body. It pumps the blood and supplies it to all organs of the whole body. Prediction of occurrences of heart diseases in the medical field is significant work. Data analytics is useful for prediction from more information and it helps the medical center to predict various diseases. A huge amount of patient-related data is maintained on monthly basis. The stored data can be useful for the source of predicting the occurrence of future diseases. Some of the data mining and machine learning techniques are used to predict heart diseases, such as Artificial Neural Network (ANN), Random Forest,and Support Vector Machine (SVM).Prediction and diagnosingof heart disease become a challenging factor faced by doctors and hospitals both in India and abroad. To reduce the large scale of deaths from heart diseases, a quick and efficient detection technique is to be discovered. Data mining techniques and machine learning algorithms play a very important role in this area. The researchers accelerating their research works to develop software with thehelp of machine learning algorithms which can help doctors to decide both prediction and diagnosing of heart disease. The main objective of this research project is to predict the heart disease of a patient using machine learning algorithms.


Author(s):  
Abhay Agrahary

Heart disease is one of the most fatal problems in the whole world, which cannot be seen with a naked eye and comes instantly when its limitations are reached. Therefore, it needs accurate diagnosis at accurate time. Health care industry produced huge amount of data every day related to patients and diseases. However, this data is not used efficiently by the researchers and practitioners. Today healthcare industry is rich in data however poor in knowledge. There are various data mining and machine learning techniques and tools available to extract effective knowledge from databases and to use this knowledge for more accurate diagnosis and decision making. Increasing research on heart disease predicting systems, it become significant to summarize the completely incomplete research on it. The main objective of this research paper is to summarize the recent research with comparative results that has been done on heart disease prediction and also make analytical conclusions. From the study, it is observed Naive Bayes with Genetic algorithm; Decision Trees and Artificial Neural Networks techniques improve the accuracy of the heart disease prediction system in different scenarios. In this paper commonly used data mining and machine learning techniques and their complexities are summarized.


2021 ◽  
Vol 36 (1) ◽  
pp. 609-615
Author(s):  
Mandhapati Rajesh ◽  
Dr.K. Malathi

Aim: Predicting the Heartdiseases using medical parameters of cardiac patients to get a good accuracy rate using machine learning methods like innovative Decision Tree (DT) algorithm. Materials and Methods: Supervised Machine learning Techniques with innovative Decision Tree (N = 20) and K Nearest Neighbour (KNN) (N = 20) are performed with five different datasets at each time to record five samples. Results: The Decision Tree is used to predict heart disease with the help of various medical conditions, the accuracy is achieved for DT is 98% and KNN is 72.2%. The two algorithms Decision Tree and KNN are statistically insignificant (=.737) with the independent sample T-Test value (p<0.005) with a confidence level of 95%. Conclusion: Prediction and classification of heart disease significantly seem to be better in DT than KNN.


2020 ◽  
Vol 8 (5) ◽  
pp. 1577-1580

Heart disease is most common now a days and it is a very serious problem. Machine learning provides a best way for predicting heart disease. The aim of this paper is to develop simple, light weight approach for detecting heart disease by machine learning techniques. Machine learning can be implemented in heart disease prediction. In this paper different machine learning techniques have been used and it compares the result using various performance metrics. This study aims to perform comparative analysis of heart disease detection using publicly available dataset collected from UCI machine learning repository. There are various datasets available such as Switzerland dataset, Hungarian dataset and Cleveland dataset. Here Cleveland dataset is used which is having 303 records of patients along with 14 attributes are used for this study and testing. These datasets are preprocessed by removing all the noisy and missing data from the dataset. And then the preprocessed dataset are used for analysis. In this study six different machine learning techniques were used for comparison based on various performance metrics. The analysis shows that out of six techniques SVM gives the best result with 89.34%. A GUI is developed for the prediction of heart disease.


2020 ◽  
Vol 28 (2) ◽  
pp. 253-265 ◽  
Author(s):  
Gabriela Bitencourt-Ferreira ◽  
Amauri Duarte da Silva ◽  
Walter Filgueira de Azevedo

Background: The elucidation of the structure of cyclin-dependent kinase 2 (CDK2) made it possible to develop targeted scoring functions for virtual screening aimed to identify new inhibitors for this enzyme. CDK2 is a protein target for the development of drugs intended to modulate cellcycle progression and control. Such drugs have potential anticancer activities. Objective: Our goal here is to review recent applications of machine learning methods to predict ligand- binding affinity for protein targets. To assess the predictive performance of classical scoring functions and targeted scoring functions, we focused our analysis on CDK2 structures. Methods: We have experimental structural data for hundreds of binary complexes of CDK2 with different ligands, many of them with inhibition constant information. We investigate here computational methods to calculate the binding affinity of CDK2 through classical scoring functions and machine- learning models. Results: Analysis of the predictive performance of classical scoring functions available in docking programs such as Molegro Virtual Docker, AutoDock4, and Autodock Vina indicated that these methods failed to predict binding affinity with significant correlation with experimental data. Targeted scoring functions developed through supervised machine learning techniques showed a significant correlation with experimental data. Conclusion: Here, we described the application of supervised machine learning techniques to generate a scoring function to predict binding affinity. Machine learning models showed superior predictive performance when compared with classical scoring functions. Analysis of the computational models obtained through machine learning could capture essential structural features responsible for binding affinity against CDK2.


Author(s):  
Augusto Cerqua ◽  
Roberta Di Stefano ◽  
Marco Letta ◽  
Sara Miccoli

AbstractEstimates of the real death toll of the COVID-19 pandemic have proven to be problematic in many countries, Italy being no exception. Mortality estimates at the local level are even more uncertain as they require stringent conditions, such as granularity and accuracy of the data at hand, which are rarely met. The “official” approach adopted by public institutions to estimate the “excess mortality” during the pandemic draws on a comparison between observed all-cause mortality data for 2020 and averages of mortality figures in the past years for the same period. In this paper, we apply the recently developed machine learning control method to build a more realistic counterfactual scenario of mortality in the absence of COVID-19. We demonstrate that supervised machine learning techniques outperform the official method by substantially improving the prediction accuracy of the local mortality in “ordinary” years, especially in small- and medium-sized municipalities. We then apply the best-performing algorithms to derive estimates of local excess mortality for the period between February and September 2020. Such estimates allow us to provide insights about the demographic evolution of the first wave of the pandemic throughout the country. To help improve diagnostic and monitoring efforts, our dataset is freely available to the research community.


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