scholarly journals Mathematical аnalysis of kidney transplant demand and availability

2018 ◽  
Vol 19 (4) ◽  
pp. 27-33
Author(s):  
M. G. Minina ◽  
N. A. Ignatov ◽  
S. B. Truhmanov
Keyword(s):  
Kidney Transplantation ◽  
Random Process ◽  
Kidney Transplant ◽  
Process Analysis ◽  
Linear Trend ◽  
Qualitative Change ◽  
Annual Number ◽  
Kidney Transplants ◽  
Saturation Limit ◽  
Number Of Patients

Aim. To analyse the dynamics of the need and availability of donor kidneys for transplantation. To construct the predictions for the number of waiting lists. To analyse the annual number of kidney transplants and the availability ofdonor kidney.Materials and methods. Data base of Eurotransplant International Foundation 1969–2015 has been analyzed. We built a forecast of the kidney waiting list, kidney transplants quantity and availability of kidney grafts up to 2030.Results. Random process analysis of kidney transplant recipients number has shown an increasing linear trend. Growing linear trend is due to the inability to fully meet the increasing need for a kidney transplant. Presence of a regular stochastic component is revealed that provides random fl uctuations in the number of patients waiting for kidney transplantation with a period of 35–40 years. Random process of the number of kidney transplants showed an exponential asymptotic trend growing to a certain saturation value. Estimation of its autocorrelation function showed the absence of regular stochastic components in it. Preservation of 1969–2015 dynamics for the period 2015–2030 allows to suggest a signifi cant increase in the number of people waiting for transplant and a decrease in the availability of donor kidneys.Conclusion. The number of donor kidney transplantations tends to saturation limit, and limit is already lower than the current need for donor kidneys. The increase in the number of kidney transplantation programs and the improvement of organ donation system may lead to a limited increase in annual number of transplants and, possibly, the saturation limit, but not to a qualitative change in the dynamics of reduced availability of donor kidneys. A qualitative change in this dynamics towards increasing accessibility, is possible perhaps through activities that affect factors causing a constant increase in the number of people who need a transplant.

scholarly journals Consulta de enfermagem no pré e pós-operatório de transplante renal: faz a diferença?

2009 ◽  
Vol 3 (2) ◽  
pp. 237
Author(s):  
Adriana Valongo Zani ◽  
Giovana Paz ◽  
Glaucimara Boniotti
Keyword(s):  
Renal Failure ◽  
Kidney Transplantation ◽  
Data Collection ◽  
Kidney Transplant ◽  
Professional Practice ◽  
Thematic Analysis ◽  
Descriptive Study ◽  
Qualitative Approach ◽  
Number Of Patients ◽  
Random Draw

ABSTRACTObjective: to describe the patient’s knowledge with chronic renal failure submitted to kidney transplantation on the importance of consultation with nursing for his treatment. Methodology: this is about an exploratory-descriptive study from qualitative approach. The data collection was from January to December 2007. The sample consisted of 36 patients undergoing kidney transplant from a total of 400. For the choice of the patients was a random draw simple daily. For data collection was used a questionnaire consisting of 11 questions concerning the information about the kidney transplant. For organization of the results was used thematic analysis proposed by Minayo. Results: as for nursing consultation for a significant number of patients claiming to be of importance to them, since they make them safer, take your questions and will be better targeted.  Conclusion: confirming the effectiveness of professional practice of nurses in the monitoring of renal patients who is subject to renal transplantation. Descriptors: nursing; kidney transplantation; chronic renal failure.RESUMOObjetivo: descrever o conhecimento do paciente portador de insuficiência renal crônica submetido a transplante renal referente à importância da consulta de enfermagem para seu tratamento. Metodologia: tratou-se de um estudo descritivo-exploratório com abordagem qualitativa. O período de coleta foi de janeiro a dezembro de 2007. A amostra foi constituída por 36 pacientes submetidos a transplante renal de um total de 400. Para a escolha dos pacientes foi realizado um sorteio aleatório simples diário. Para a coleta de dados foi utilizado um questionário composto por 11 perguntas referentes as informações sobre o transplante renal. Para organização dos resultados foi utilizada a análise temática proposta por Minayo. Resultados: quanto à consulta de enfermagem um número significativo de pacientes afirmam ser de importância aos mesmos, uma vez que os tornam mais seguros, tiram suas dúvidas e  serão melhor orientados. Conclusão: estes dados vêm a confirmar a eficácia da atuação profissional do enfermeiro no acompanhamento dos pacientes renais que se submeterão ao transplante renal. Descritores: enfermagem; transplante renal; insuficiência renal crônica.RESUMENObjetivo: describir el conocimiento del paciente portador de insuficiência renal crónica sometido a transplante renal, referente a la importáncia de la consulta de enfermería para su tratamiento. Metodologia: studio exploratório y descriptivo con abordaje cualitativa. El período de recogida fue de enero a diciembre de 2007. La muestra consistió de 36 pacientes sometidos a trasplante de riñón de un total de 400. Para la elección de los pacientes fue de un sorteo aleatorio simple diario. Para la recogida de datos se utilizó un cuestionario de 11 preguntas relativas a la información sobre el trasplante de riñón. Para la organización de los resultados se utilizó el análisis temático propuesto por Minayo. Resultados: cuanto a consulta de enfermeria, un número significativo de pacientes, afirma ser de importância a los mismos, una vez que los hacen mas seguros, disipan sus dudas y serán mejor orientados. Conclusión: lo que confirma la eficácia de la actuación profesional del enfermero, en el acompañamiento de los pacientes renales que se sometieron al transplante renal. Descriptores: enfermería; transplante renal; insuficiéncia renal crónica.

scholarly journals Spontaneous Ureterocolic Fistula between Nonfunctioning Kidney Transplant Ureter and Colon in Setting of Diverticulitis

2021 ◽  
Vol 2021 ◽  
pp. 1-3
Author(s):  
Madison K. Krischak ◽  
Jeffrey R. Ord ◽  
Ashton A. Connor ◽  
Andrew S. Barbas
Keyword(s):  
Kidney Transplantation ◽  
Renal Transplant ◽  
Diverticular Disease ◽  
Sigmoid Colon ◽  
Kidney Transplant ◽  
Rare Condition ◽  
Kidney Transplants

Ureterocolic fistula is a rare condition that most commonly occurs in the setting of diverticular disease. The development of a ureterocolic fistula following kidney transplantation is even rarer, with no prior cases in the literature to our knowledge. We describe the case of a patient with three prior failed kidney transplants who developed a fistula between the sigmoid colon and nonfunctioning renal transplant ureter in the setting of diverticulitis.

scholarly journals Implementation of State Programs to Reduce Chronic Kidney Failure in Azerbaijan

2020 ◽  
Vol 6 (4) ◽  
pp. 147-152
Author(s):  
F. Babaev
Keyword(s):  
Renal Failure ◽  
Kidney Transplantation ◽  
Chronic Renal Failure ◽  
Renal Insufficiency ◽  
Kidney Transplant ◽  
Chronic Renal Insufficiency ◽  
The State ◽  
State Program ◽  
Number Of Patients

In the general structure of chronic renal failure, up to 40% is terminal chronic renal failure requiring replacement renal therapy, particularly hemodialysis, peritoneal dialysis, and kidney transplantation. Azerbaijan has an annual increase in the number of patients with chronic renal failure by 10–12 per cent. In 2006, the State Program of Measures for Chronic Renal Failure 2006–2011 was adopted to reduce the prevalence and improve the quality of treatment for chronic renal failure. The implementation of this program allowed to create a state register of patients with chronic renal failure, expand the network of hemodialysis centers, increase availability in medicines, use modern methods of early diagnosis and prevention of chronic renal failure. In order to further improve nephrological assistance, the second stage of the State Program for the Reduction of Chronic Renal Insufficiency in Azerbaijan for 2011–2016 years has been adopted. The effectiveness of Program to reduce chronic renal insufficiency in Azerbaijan has been demonstrated by the improvement of the quality of medical care, the increase in life expectancy and the reduction of mortality. It should be noted that thanks to this Program, the number of patients receiving hemodialysis per 21.0–25.0% increases annually. In 2010, the Republican Clinical Urological Hospital opened a kidney transplant center. The main objectives of the Program are to reduce mortality from chronic renal failure, Increasing hemodialysis centers according to the number of patients with chronic renal failure and kidney transplant operations. In 2016, the State Program of chronic renal failure for 2016–2020 was adopted. Some progress has been made during the implementation of the State Program. In many parts of the Azerbaijan, the population is provided with dialysis assistance free of charge from the State budget. By January 1, 2020, there are 3 kidney transplantation centers and 45 hemodialysis centers equipped with 716 dialysis devices.

scholarly journals Current Pharmacological Intervention and Medical Management for Diabetic Kidney Transplant Recipients

Pharmaceutics ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 413
Author(s):  
Theerawut Klangjareonchai ◽  
Natsuki Eguchi ◽  
Ekamol Tantisattamo ◽  
Antoney J. Ferrey ◽  
Uttam Reddy ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Kidney Transplantation ◽  
Kidney Transplant ◽  
Pharmacological Intervention ◽  
Diabetic Patients ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Kidney Allograft ◽  
Post Transplant ◽  
Glucose Management

Hyperglycemia after kidney transplantation is common in both diabetic and non-diabetic patients. Both pretransplant and post-transplant diabetes mellitus are associated with increased kidney allograft failure and mortality. Glucose management may be challenging for kidney transplant recipients. The pathophysiology and pattern of hyperglycemia in patients following kidney transplantation is different from those with type 2 diabetes mellitus. In patients with pre-existing and post-transplant diabetes mellitus, there is limited data on the management of hyperglycemia after kidney transplantation. The following article discusses the nomenclature and diagnosis of pre- and post-transplant diabetes mellitus, the impact of transplant-related hyperglycemia on patient and kidney allograft outcomes, risk factors and potential pathogenic mechanisms of hyperglycemia after kidney transplantation, glucose management before and after transplantation, and modalities for prevention of post-transplant diabetes mellitus.

scholarly journals COVID-19—Importance for Patients on the Waiting List and after Kidney Transplantation—A Single Center Evaluation in 2020–2021

Pathogens ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 429
Author(s):  
Simone C. Boedecker ◽  
Pascal Klimpke ◽  
Daniel Kraus ◽  
Stefan Runkel ◽  
Peter R. Galle ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Waiting List ◽  
Smoking History ◽  
Immunocompromised Patients ◽  
Dialysis Patients ◽  
Vaccination Programs ◽  
Mild Disease ◽  
Probability Of Survival ◽  
Number Of Patients ◽  
Immunosuppressed Patients

(1) Background: Dialysis patients and recipients of a kidney allograft are at high risk for infection with SARS-CoV-2. It has been shown that the development of potent neutralizing humoral immunity against SARS CoV-2 leads to an increased probability of survival. However, the question of whether immunocompromised patients develop antibodies has not yet been sufficiently investigated; (2) Methods: SARS-CoV-2 antibodies were examined in hemodialysis patients on the waiting list for kidney transplantation as well as patients after kidney transplantation. Patients were interviewed about symptoms and comorbidities, BMI, and smoking history; (3) Results: SARS-CoV-2 antibodies were found in 16 out of 259 patients (6%). The trend of infections here reflects the general course of infection in Germany with a peak in November/December of 2020. Remarkably, patients on the waiting list experienced only mild disease. In contrast, transplanted patients had to be hospitalized but recovered rapidly from COVID-19. Most interesting is that all immunosuppressed patients developed antibodies against SARS-CoV-2 after infection; (4) Conclusions: Even with extensive hygiene concepts, an above-average number of patients were infected with SARS-CoV-2 during the second wave of infections in Germany. Because SARS-CoV-2 infection triggered the formation of antibodies even in these immunocompromised patients, we expect vaccination to be effective in this group of patients. Thus, dialysis patients and patients after kidney transplantation should be given high priority in vaccination programs.

scholarly journals 570. “I don’t know”: The Typical Response When Taking Pneumococcal Immunization Histories in Kidney Transplant Candidates

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S349-S351
Author(s):  
Jahanavi M Ramakrishna ◽  
Tambi Jarmi ◽  
Claudia R Libertin
Keyword(s):  
Infectious Disease ◽  
Kidney Transplant ◽  
Pneumococcal Vaccine ◽  
Patient Population ◽  
Pneumococcal Vaccination ◽  
Prior History ◽  
Vaccine Preventable Diseases ◽  
Number Of Patients ◽  
Order Completion ◽  
History Of

Abstract Background Vaccine-preventable diseases account for significant morbidity and mortality in the kidney transplant (KT) patient population. AST Guidelines support review and documentation of pneumococcal vaccines in KT candidate infectious disease (ID) evaluations. The objective of this study is to determine the number of KT candidates screened for prior pneumococcal immunizations and the frequency of vaccines ordered by providers when indicated at Mayo Clinic Florida’s (MCF) Transplant Center. Methods This study was an institution-based retrospective analysis of all KT candidates evaluated at MCF from December 2, 2019 – January 14, 2020. Data collection was obtained by electronic health record review. Outcomes included known history and documentation rates of prior pneumococcal vaccinations (both Prevnar 13 and Pneumovax 23) by infectious disease (ID) providers, as well as pneumococcal vaccine order frequency during ID pre-transplant evaluation when indicated. Data analysis was done using simple descriptive statistics. Results Sixty-one patients underwent KT evaluation during the study period. Among the 61 patients, 20 (32.8%) and 20 (32.8%) had a known prior history of receiving Prevnar 13 and Pneumovax 23 vaccinations, respectively. Vaccine history was unknown for Prevnar 13 and Pneumovax 23 in 39 (63.9%) patients. Vaccine status was not documented by ID providers in 2 (3.3%) patients. When appropriate, ID providers ordered Prevnar 13 and Pneumovax 23 in 38 (92.7%) and 41 (100%) patients, respectively. Orders included both electronic and written documentation to account for patients planning immunization elsewhere. Of the 38 patients advised to receive the Prevnar 13 vaccine, 17 (41.5%) patients were documented completing immunization. Pneumovax 23 order completion rates were not recorded since the study period only lasted six weeks due to closure by COVID-19. Table 1. Pneumococcal Vaccine History Documentation Rates Obtained by Patient Recall or Records Table 2. Pneumococcal Vaccine Order Rates at Pre-Kidney Transplant Consultations Table 3. Prevnar 13 Order Completion Rate by Documentation Conclusion The data reflect a high number of patients who either do not recall or have documentation of prior pneumococcal vaccination available at time of KT ID evaluation. Providers documented history of pneumococcal vaccinations extremely well, ordering immunizations when necessary. This study highlights lack of portability of immunization histories in a given patient population and opportunity for improved care. Disclosures Claudia R. Libertin, MD, Pfizer, Inc. (Grant/Research Support, Research Grant or Support)

scholarly journals A Collaborative Model to Implement Flexible, Accessible and Efficient Oncogenetic Services for Hereditary Breast and Ovarian Cancer: The C-MOnGene Study

Cancers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2729
Author(s):  
Julie Lapointe ◽  
Michel Dorval ◽  
Jocelyne Chiquette ◽  
Yann Joly ◽  
Jason Robert Guertin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Ovarian Cancer ◽  
Genetic Counseling ◽  
Evidence Base ◽  
Annual Number ◽  
Breast And Ovarian Cancer ◽  
Patient Centered ◽  
Collaborative Model ◽  
Counseling And Testing ◽  
Number Of Patients

Medical genetic services are facing an unprecedented demand for counseling and testing for hereditary breast and ovarian cancer (HBOC) in a context of limited resources. To help resolve this issue, a collaborative oncogenetic model was recently developed and implemented at the CHU de Québec-Université Laval; Quebec; Canada. Here, we present the protocol of the C-MOnGene (Collaborative Model in OncoGenetics) study, funded to examine the context in which the model was implemented and document the lessons that can be learned to optimize the delivery of oncogenetic services. Within three years of implementation, the model allowed researchers to double the annual number of patients seen in genetic counseling. The average number of days between genetic counseling and disclosure of test results significantly decreased. Group counseling sessions improved participants’ understanding of breast cancer risk and increased knowledge of breast cancer and genetics and a large majority of them reported to be overwhelmingly satisfied with the process. These quality and performance indicators suggest this oncogenetic model offers a flexible, patient-centered and efficient genetic counseling and testing for HBOC. By identifying the critical facilitating factors and barriers, our study will provide an evidence base for organizations interested in transitioning to an oncogenetic model integrated into oncology care; including teams that are not specialized but are trained in genetics.

scholarly journals Abdominal Panniculectomy Can Simplify Kidney Transplantation in Obese Patients

2021 ◽  
pp. 1-8
Author(s):  
Dominik Promny ◽  
Theresa Hauck ◽  
Aijia Cai ◽  
Andreas Arkudas ◽  
Katharina Heller ◽  
...  
Keyword(s):  
Wound Healing ◽  
Kidney Transplantation ◽  
Postoperative Complications ◽  
Kidney Transplant ◽  
Interdisciplinary Approach ◽  
Wound Complications ◽  
Obese Patients ◽  
Patient Cohort ◽  
Transplant Candidates ◽  
Stage Renal Disease

<b><i>Background:</i></b> Obesity is frequently present in patients suffering from end-stage renal disease (ESRD). However, overweight kidney transplant candidates are a challenge for the transplant surgeon. Obese patients tend to develop a large abdominal panniculus after weight loss creating an area predisposed to wound-healing disorders. Due to concerns about graft survival and postoperative complications after kidney transplantation, obese patients are often refused in this selective patient cohort. The study aimed to analyze the effect of panniculectomies on postoperative complications and transplant candidacy in an interdisciplinary setting. <b><i>Methods:</i></b> A retrospective database review of 10 cases of abdominal panniculectomies performed in patients with ESRD prior to kidney transplantation was conducted. <b><i>Results:</i></b> The median body mass index was 35.2 kg/m<sup>2</sup> (range 28.5–53.0 kg/m<sup>2</sup>) at first transplant-assessment versus 31.0 kg/m<sup>2</sup> (range 28.0–34.4 kg/m<sup>2</sup>) at panniculectomy, and 31.6 kg/m<sup>2</sup> (range 30.3–32.4 kg/m<sup>2</sup>) at kidney transplantation. We observed no major postoperative complications following panniculectomy and minor wound-healing complications in 2 patients. All aside from 1 patient became active transplant candidates 6 weeks after panniculectomy. No posttransplant wound complications occurred in the transplanted patients. <b><i>Conclusion:</i></b> Abdominal panniculectomy is feasible in patients suffering ESRD with no major postoperative complications, thus converting previously ineligible patients into kidney transplant candidates. An interdisciplinary approach is advisable in this selective patient cohort.

scholarly journals A Kidney Transplant Recipient with Recurrent Henoch-Schönlein Purpura Nephritis Successfully Treated with Steroid Pulse Therapy and Epipharyngeal Abrasive Therapy

Nephron ◽  
2020 ◽  
pp. 1-5
Author(s):  
Mika Fujimoto ◽  
Kan Katayama ◽  
Kouhei Nishikawa ◽  
Shoko Mizoguchi ◽  
Keiko Oda ◽  
...  
Keyword(s):  
Renal Function ◽  
Kidney Transplantation ◽  
Transplant Recipient ◽  
Kidney Transplant ◽  
Kidney Transplant Recipient ◽  
Pulse Therapy ◽  
Steroid Pulse Therapy ◽  
Steroid Pulse ◽  
Schonlein Purpura ◽  
Purpura Nephritis

There is no specific treatment for recurrent Henoch-Schönlein purpura nephritis (HSPN) in a transplanted kidney. We herein report a case of a kidney transplant recipient with recurrent HSPN that was successfully treated with steroid pulse therapy and epipharyngeal abrasive therapy (EAT). A 39-year-old Japanese man developed HSPN 4 years ago and had to start hemodialysis after 2 months despite receiving steroid pulse therapy followed by oral prednisolone, plasma exchange therapy, and cyclophosphamide pulse therapy. He had undergone tonsillectomy 3 years earlier in the hopes of achieving a better outcome of a planned kidney transplantation and received a living-donor kidney transplantation from his mother 1 year earlier. Although there were no abnormalities in the renal function or urinalysis 2 months after transplantation, a routine kidney allograft biopsy revealed evidence of mesangial proliferation and cellular crescent formation. Mesangial deposition for IgA and C3 was noted, and he was diagnosed with recurrent HSPN histologically. Since the renal function and urinalysis findings deteriorated 5 months after transplantation, 2 courses of steroid pulse therapy were performed but were ineffective. EAT using 0.5% zinc chloride solution once per day was combined with the third course of steroid pulse therapy, as there were signs of chronic epipharyngitis. His renal function recovered 3 months after daily EAT and has been stable for 1.5 years since transplantation. Daily EAT continued for &#x3e;3 months might be a suitable strategy for treating recurrent HSPN in cases of kidney transplantation.

Sign in / Sign up

Export Citation Format

Share Document