scholarly journals THE IMPACT OF COMBINATION ANTIHYPERTENSION THERAPY ON THE MAIN PARAMETERS OF STRUCTURAL AND FUNCTIONAL CONDITION OF THE LEFT VENTRICLE MYOCARDIUM IN NON-CONTROLLED ARTERIAL HYPERTENSION WITH DEPRESSION SPECTRUM DISORDER

2015 ◽  
Vol 14 (5) ◽  
pp. 23
Author(s):  
V. V. Skibitsky ◽  
A. V. Skibitsky ◽  
A. V. Fendrikova
Keyword(s):  
Left Ventricle ◽  
Arterial Hypertension ◽  
Functional Condition ◽  
Spectrum Disorder ◽  
The Impact ◽  
Antihypertension Therapy ◽  
Left Ventricle Myocardium

scholarly journals The effect of pulmonary arterial hypertension specific treatment on the left ventricle in patients with pulmonary arterial hypertension

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
S.A Mouratoglou ◽  
J.N Wessels ◽  
J.T Marcus ◽  
L.J Meijboom ◽  
F Handoko-De Man ◽  
...  
Keyword(s):  
Pulmonary Arterial Hypertension ◽  
Left Ventricle ◽  
Stroke Volume ◽  
Arterial Hypertension ◽  
Left Atrium ◽  
Initial Contour ◽  
End Diastolic Volume ◽  
Pulmonary Arterial ◽  
The Impact

Abstract Background Pulmonary arterial hypertension (PAH) is characterized by right ventricular (RV) pressure overload, leading to RV dilation, failure and death. In the course of the disease, the left ventricle (LV) is often impaired, due to interventricular interaction. Although the impact of PAH treatment on the RV has been well described, less is known on the LV. Purpose To examine effects of advanced PAH treatments on the volumes, function and strain of the left atrium and ventricle. Methods This is a retrospective study. All patients underwent CMR and right heart catheterization, both at diagnosis and at 12-months follow up. Ventricular volumes and LV filling rate were calculated from the stack of short axis cine images using Simpsons method while left atrial (LA) volumes from the 4-chamber cine images using the area-length method. Tissue tracking was used for the evaluation of myocardial deformation. The LV endocardial and epicardial borders were manually delineated in all analysed sections with the initial contour set at end-diastole. All analyses were performed offline using dedicated software. Results In total, 66 patients (mean age 56.3±17.9 years, 67%women, 77%idiopathic and heritable PAH, 23% connective tissue disease associated PAH) and 29 normal controls were included. The improvement in metrics of right and left heart size and function after the initiation of advanced PAH treatment, are presented in panel A. Of note, LV stroke volume was markedly increased (54.6±19.6ml at baseline vs 70.8±21.7ml at follow up, p<0.0001) to reach controls. LV filling was markedly increased in latter two-thirds of the diastolic phase (panel B), especially at atrial kick point (arrow). Change in LA max volume was associated with changes in diastolic filling (r=0.354, p=0.004), LV end-diastolic and end-systolic volumes and stroke volume. These correlations were more robust in patients that increased LV filling compared to those that failed to increase LV filling (panels C-E). No association between changes in LV circumferential strain and LV volume load was observed. A weak correlation of change of LV peak longitudinal strain with stroke volume (r=−0.345, p=0.006), LV end diastolic volume (r=−0.284, p=0.027), LV ejection fraction (r=−0.337, p=0.008) and LA maximum area (r=−0.447, p<0.0001) was observed. The changes of LV strain showed no correlation with the changes in patients' haemodynamics. Conclusion Improvement in stroke volume after the initiation of advanced PAH treatment is associated with an increase in LA size, LV end diastolic volume and normalisation of strain. This reflects the improved filling state of the left ventricle and the potential of the left atrium to monitor treatment effects. Changes after PAH treatment Funding Acknowledgement Type of funding source: None

Occupational conditionality of cardiovascular diseases in workers exposed to fibrogenic dust

2019 ◽  
pp. 56-60
Author(s):  
Tatyana Yu. Obukhova
Keyword(s):  
Cardiovascular Diseases ◽  
Left Ventricle ◽  
Arterial Hypertension ◽  
Sinus Tachycardia ◽  
Cardiovascular Disorders ◽  
Single Factor ◽  
Length Of Service ◽  
Single Factor Analysis ◽  
Etiologic Fraction ◽  
Left Ventricle Myocardium

Using single-factor analysis, the study covered prevalence and occupational conditionality of cardiovascular diseases in workers exposed to fibrogenic dust. The findings are higher prevalence of arterial hypertension, left ventricle myocardium hypertrophy, sinus tachycardia, obesity, hypertriglyceridemia, fasting hyperglycemia in silicosis and asbestosis patients if compared to refractory and asbestos-enrichment production workers with long length of service. Based on calculated relative risk and etiologic fraction, the authors revealed average occupational conditionality of arterial hypertension (etiologic fraction 45%), high occupational conditionality of left ventricle myocardium hypertrophy (etiologic share 59.7%), sinus tachycardia syndrome and obesity, and extremely high occupational dependence of carbohydrate metabolism (etiologic fraction 77.2%) on fibrogenic dust — that helps to assign this metabolic and cardiovascular disorders to occupationally-conditioned diseases.

scholarly journals DYNAMICS OF FUNCTIONAL CONDITION AND QUALITY OF LIFE IN PATIENTS WITH ASTHMA-COPD OVERLAP AND CONCOMITANT ARTERIAL HYPERTENSION AGAINST THE BACKGROUND OF COMPLEX THERAPY

2020 ◽  
Vol 1 ◽  
pp. 21-27
Author(s):  
Maryna Kochuieva ◽  
Hanna Tymchenko ◽  
Ivan Hrek ◽  
Yulia Zaikina
Keyword(s):  
Quality Of Life ◽  
Arterial Hypertension ◽  
Functional Status ◽  
Functional Condition ◽  
Rehabilitation Program ◽  
Shortness Of Breath ◽  
Complex Therapy ◽  
Active Rehabilitation ◽  
The Impact

Patients with ACO have significant poorer health-related quality of life and more severe functional limitations compared to asthma and COPD alone. Most commonly, chronic respiratory disease is associated with cardiovascular disease, such as arterial hypertension. However, the impact of concomitant cardiac diseases on the quality of life and functional status of patients with ACO remains poorly understood. The aim of the work was to study dynamics of functional condition and quality of life in with ACO and concomitant AH against the background of complex therapy. Materials and methods. We selected for participating in the study 100 patients with ACO and concomitant AH. Examination of the patients included: clinical methods, spirometry, and questinaries – mMRS, CAT, SGRQ, performing 6MWT. Results. After 16 weeks of treatment there were no changes in lung functional status in patients on standard treatment, at the same time, in group of patients who had an active rehabilitation program, there was a significant improvement in the bronchial response to the action of bronchodilators, although other indicators of the functional status of the lungs didn't show significant changes. Patients who additionally used an active rehabilitation program had a significant improvement in clinical symptoms, shortness of breath, and quality of life according to CAT, mMRC, and SGRQ scores, respectively. There was also a significant increase in distance during the 6MWT in this group of patients. Conclusions. Conducting an active rehabilitation program (physical rehabilitation in combination with an educational program and self-management) in group of patients with ACO and concomitant AH, who are on standard medical treatment, significantly improves the bronchial response to the action of bronchodilators, decreases clinical manifestations, shortness of breath and improve quality of life and exercise tolerance, according to CAT, mMRC, SGRQ and 6MWT questionnaires, respectively.

scholarly journals Оцінка стану серцево-судинної системи машиністів локомотивів

2012 ◽  
Vol 3 (2) ◽  
pp. 42-47
Author(s):  
O. Р. Korzhenevs’ka ◽  
O. В. Severynovs’ka
Keyword(s):  
Blood Pressure ◽  
Left Ventricle ◽  
Arterial Pressure ◽  
Arterial Hypertension ◽  
Cardiovascular System ◽  
The State ◽  
Daily Work ◽  
Daily Monitoring ◽  
Structural Abnormalities ◽  
Left Ventricle Myocardium

With the help of daily monitoring of blood pressure we assessed the state of the cardiovascular system of foot-platemen of the Prydniprovsk railway Pjatykhatky Depot. Foot-platemen having the I stage of arterial hypertension demonstrated the 11–17% increase of arterial pressure during daily work. It is related to inefficient adaptation to the physical and psychoemotional overloads. With aggravation of the disease the change of arterial pressure during the work, especially night work, ismisaligned and characterised by considerable structural abnormalities of the left ventricle myocardium.

Te inf uence of ergonomic factors on the formation of occupational risk of health disorders of agricultural machine operators

2019 ◽  
Vol 1 (7) ◽  
pp. 400-405
Author(s):  
Tamara A. Novikova ◽  
Aleksey N. Danilov ◽  
Vladimir F. Spirin
Keyword(s):  
Physical Activity ◽  
Functional Condition ◽  
Anthropometric Data ◽  
Agricultural Machine ◽  
Machine Operators ◽  
Health Disorders ◽  
Space Layout ◽  
Combine Harvesters ◽  
High Degree ◽  
The Impact

Introduction. T e leading place in the structure of occupational morbidity of agricultural machine operators is occupied by vertebroneurological diseases, the development of which can be associated with the impact of ergonomic factors of labor activity. T e aim of the study is to assess the ergonomic factors of working conditions on mobile agricultural machinery and to identify their impact on the formation of health disorders of agricultural machine operators. Materials and methods. Complex physiological and ergonomic researches at operation of tractors and combine harvesters of old samples of domestic production including an assessment of the organization of workplaces on compliance to requirements of ergonomics and anthropometric data of workers, temporary, statodynamic, biomechanical characteristics of working poses and movements, a functional condition of machine operators (130 people aged 20–45 years with professional experience of work not less than three years) in dynamics of a work shift are carried out. Anthropometric studies were conducted among male machine operators (663 people) aged 18–59 years and with experience in the profession for more than three years. Results. The discrepancy between the size and space-layout parameters of workplaces ergonomic requirements and anthropometric data of machine operators, causing the formation of uncomfortable working positions, increasing physical activity and the severity of the labor process. A high degree of correlation between changes in the parameters of the neuromuscular system and the severity of the discrepancy between the ergonomic parameters of anthropometric characteristics of machine operators (r=0,7). T e results of the research allowed to determine the priority measures for the prevention of vertebroneurological diseases in agricultural machine operators. Conclusions. T e organization of workplaces on domestic tractors and combine harvesters of old samples does not meet the ergonomic requirements and anthropometric data of machine operators, which is the reason for the formation of an uncomfortable working posture, increased statodynamic physical activity, early development of fatigue and fatigue in the process, which can cause the development of pathological conditions of the spine and ligamentous apparatus. Ergonomic improvement of workplaces is one of the priority measures to preserve the health of agricultural machine operators.

scholarly journals Effectiveness of Equine-Assisted Activities and Therapies for Improving Adaptive Behavior and Motor Function in Autism Spectrum Disorder

2021 ◽  
Vol 10 (8) ◽  
pp. 1726
Author(s):  
Leonardo Zoccante ◽  
Michele Marconi ◽  
Marco Luigi Ciceri ◽  
Silvia Gagliardoni ◽  
Luigi Alberto Gozzi ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Motor Function ◽  
Adaptive Behavior ◽  
Preliminary Evidence ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Parental Distress ◽  
Effective Option ◽  
The Impact ◽  
Equine Assisted

Equine-assisted activities and therapies (EAAT) have been suggested to improve adaptive behavior, and possibly motor function, in autism spectrum disorder (ASD). This study investigated the effects of EAAT on adaptive behavior and motor function in 15 children with ASD (13 males) aged 7–15 years as well as the impact of EAAT on the magnitude of stress in the parent–child system and the evolution in the child interaction with both the trained therapist and the therapeutic animal through the 20 weekly sessions of EAAT. EAAT were associated with greater adaptive behavior and coordination (all p ≤ 0.01) as well as a progressive improvement in the child’s abilities to respond to the increasing complexity of such form of positive behavioral support (all p < 0.001). However, EAAT did not prove to be effective in reducing parental distress. Collectively, preliminary evidence presented here may have important public health implications and gives reason to hope that EAAT could possibly be an effective option in ASD, warranting further investigation of its potential benefits in clinical trials among larger samples.

scholarly journals The Impact of COVID-19 on the Adaptive Functioning, Behavioral Problems, and Repetitive Behaviors of Italian Children with Autism Spectrum Disorder: An Observational Study

Children ◽  
2021 ◽  
Vol 8 (2) ◽  
pp. 96
Author(s):  
Martina Siracusano ◽  
Eugenia Segatori ◽  
Assia Riccioni ◽  
Leonardo Emberti Gialloreti ◽  
Paolo Curatolo ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Behavioral Problems ◽  
Adaptive Functioning ◽  
Children With Autism ◽  
Autism Spectrum ◽  
Repetitive Behaviors ◽  
Assessment System ◽  
Spectrum Disorder ◽  
Adaptive Skills ◽  
The Impact

Children with autism spectrum disorder (ASD) and their families have represented a fragile population on which the extreme circumstances of the COVID-19 outbreak may have doubly impaired. Interruption of therapeutical interventions delivered in-person and routine disruption constituted some of the main challenges they had to face. This study investigated the impact of the COVID-19 lockdown on adaptive functioning, behavioral problems, and repetitive behaviors of children with ASD. In a sample of 85 Italian ASD children (mean age 7 years old; 68 males, 17 females), through a comparison with a baseline evaluation performed during the months preceding COVID-19, we evaluated whether after the compulsory home confinement any improvement or worsening was reported by parents of ASD individuals using standardized instruments (Adaptive Behavior Assessment System (Second Edition), Achenbach Child Behavior Checklist, Repetitive Behavior Scale-Revised). No significant worsening in the adaptive functioning, problematic, and repetitive behaviors emerged after the compulsory home confinement. Within the schooler children, clinical stability was found in reference to both adaptive skills and behavioral aspects, whereas within preschoolers, a significant improvement in adaptive skills emerged and was related to the subsistence of web-delivered intervention, parental work continuance, and online support during the lockdown.

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