Developmental immunology and vaccines: Immune responses to vaccines in premature infants

2004 ◽  
Vol 3 (4) ◽  
pp. 343-347 ◽  
Author(s):  
DM Roberton ◽  
H Marshall ◽  
L Dinan ◽  
C Boros ◽  
M Gold
2013 ◽  
Vol 61 (1) ◽  
pp. 24 ◽  
Author(s):  
Katherine Belov ◽  
Robert D. Miller ◽  
Julie M. Old ◽  
Lauren J. Young

Marsupial immune responses were previously touted as ‘primitive’ but we now know that the marsupial immune system is complex and on par with that of eutherian mammals. In this manuscript we review the field of marsupial immunology, focusing on basic anatomy, developmental immunology, immunogenetics and evolution. We concentrate on advances to our understanding of marsupial immune gene architecture, made possible by the recent sequencing of the opossum, tammar wallaby and Tasmanian devil genomes. Characterisation of immune gene sequences now paves the way for the development of immunological assays that will allow us to more accurately study health and disease in marsupials.


2002 ◽  
Vol 9 (3) ◽  
pp. 177-179 ◽  
Author(s):  
N. Wittenbrink ◽  
M. Zemlin ◽  
K. Bauer ◽  
C. Berek

The immune response of the neonate is poor and is dependent on passive immunity provided by maternal Ig. However, here we show that exposure of the neonate to environmental antigens induces a germinal center (GC) reaction. In the peripheral blood of premature infants one finds IgG class switched B cells expressing a selected V-gene repertoire. These data suggest that restrictions in the repertoire rather than immaturity of the immune system is responsible for the poor immune responses of the neonate.


2016 ◽  
Vol 81 (2) ◽  
pp. 384-390 ◽  
Author(s):  
Courtney M. Jackson ◽  
Casey B. Wells ◽  
Meredith E. Tabangin ◽  
Jareen Meinzen-Derr ◽  
Alan H. Jobe ◽  
...  

1997 ◽  
Vol 27 (11) ◽  
pp. 1285-1291 ◽  
Author(s):  
M. N. KOLOPP-SARDA ◽  
D. A. MONERET-VAUTRIN ◽  
B. GOBERT ◽  
G. KANNY ◽  
M. BRODSCHII ◽  
...  

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