scholarly journals Trypanosoma cruzi seroprevalence and associated risk factors in cancer patients from Southern Brazil

2016 ◽  
Vol 49 (6) ◽  
pp. 768-771 ◽  
Author(s):  
Luciane d'Avila Rosenthal ◽  
Cristiane Rios Petrarca ◽  
Marilia Arndt Mesenburg ◽  
Marcos Marreiro Villela
2018 ◽  
Vol 11 (2) ◽  
pp. 677 ◽  
Author(s):  
K Krishnaveni ◽  
Rosmi Jose ◽  
SK Sumitha ◽  
Teena Johny ◽  
Shanmuga R Sundaram ◽  
...  

2017 ◽  
Vol 27 (5) ◽  
pp. 1450-1456 ◽  
Author(s):  
Apostolos Gaitanidis ◽  
Michail Alevizakos ◽  
Michail Pitiakoudis ◽  
Doreen Wiggins

2021 ◽  
Vol 7 ◽  
Author(s):  
Aline do Nascimento Benitez ◽  
Thais Cabral Monica ◽  
Ana Carolina Miura ◽  
Micheline Sahyun Romanelli ◽  
Lucienne Garcia Pretto Giordano ◽  
...  

Although leptospirosis has been considered a major concern in urban areas, no study to date has spatially and simultaneously compared both owner and dog serology in households of major cities. Accordingly, the aim of the present study was to assess the seroprevalence of Leptospira antibodies, evaluate associated risk factors and conduct spatial analyses in 565 randomly selected households, which included 597 dog owners and 729 dogs in Londrina, Southern Brazil. Seropositivity by MAT were detected in in 11/597 (1.84%) owners and in 155/729 (21.26%) dogs. The risk factors were evaluated with logistic regression analysis and spatial factors and case distribution were evaluated with kernel density analyses. The sera of 14/155 (9.03%) dogs reacted for more than one serovar with the same titer. Canicola was the most frequent serogroup, detected in 3/11 (27.27%) owners and 76/155 (49.03%) dogs. The highest titer among the owners was 1:3,200 and was detected in the same household with a titer of 1:800 in the dog. Simultaneous owner-dog seropositivity was found in 7/565 (1.23%) households, with three reacted against serogroup Canicola. Positive owners were detected in 4/565 (0.70%) households and positive dogs were detected in 141/565 (24.95%) households. The associated risks of infection for dogs were different from those associated with infection in owners. Risk analyses for Canicola also identified specific factors of infection. Regardless of owner and dog cases were not statistically clustered, the kernel map has shown dog positivity occurrence in the same hot locations and near positive owners. The dependent variable analysis and logit model suggested a greater likelihood of peri-domiciliary contact with Leptospira. In conclusion, exposure to Leptospira infection was significantly higher in dogs than in their owners and human cases spatially overlapped dog cases, implicating dogs as potential environmental sentinels for this disease. In addition, the associated risk may vary according to serogroup, and the observed simultaneous Canicola seropositivity of owner and dog has suggested intradomicile-transmitted infection.


2014 ◽  
Vol 35 (1) ◽  
pp. 110-115
Author(s):  
Anelise Sampaio CAVALHEIRO ◽  
Mariana Jaeger FONSECA ◽  
Graciele SBRUZZI ◽  
Silvia GOLDMEIER

The objective of this study was to find out whether there are gender differences regarding socio-demographic characteristics and associated risk factors in adults monitored in an outpatient hypertension facility. Retrospective analysis of records of patients seen at the outpatient hypertension clinic in 2009-2010, in a hospital specialized in cardiology, in southern Brazil. All patients were beneficiaries from the Brazilian Unified Healthcare System (SUS). The variables considered were socio-demographic profile, anthropometric measurements and risk factors for hypertension. For statistical analysis, a significance level of 5% (p ≤ 0.05) was adopted. Of the 209 patient records assessed, most belonged to female patients (66%), 65.9% of them were married, 71.6% were white, with mean age 53.5 ± 13.8 years, and 70.1% had a sedentary behavior. Regarding risk factors, waist circumference and alcohol use were higher among men (p=0.04). It was concluded that there was no gender difference concerning the assessed variables, except for the use of alcohol.


2020 ◽  
Vol 159 ◽  
pp. 144
Author(s):  
A.B. Gardner ◽  
M.C. Liu ◽  
A. Chan ◽  
A. Rohatgi ◽  
A. Milki ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Naihma Salum Fontana ◽  
K. I. Ibrahim ◽  
P. R. Bonazzi ◽  
F. Rossi ◽  
S. C. G. Almeida ◽  
...  

AbstractTo evaluate the prognostic factors in adult cancer patients with pneumococcal bacteremia, describe episode features and the phenotypic characteristics of the isolated strains. We evaluated the episodes in patients admitted to a cancer hospital between 2009 and 2015. The outcomes were defined as 48 h mortality and mortality within 10 days after the episode. The variables evaluated were: age, sex, ethnicity, ECOG, Karnofsky score, SOFA, cancer type, metastasis, chemotherapy, radiotherapy, neutropenia, previous antibiotic therapy, community or healthcare-acquired infection, comorbidities, smoking, pneumococcal vaccination, infection site, presence of fever, polymicrobial infection, antimicrobial susceptibility, serotype and treatment. 165 episodes were detected in 161 patients. The mean age was 61.3 years; solid tumors were the most prevalent (75%). 48 h and 10-day mortality were 21% (34/161) and 43% (70/161) respectively. The 48 h mortality- associated risk factors were SOFA and polymicrobial bacteremia; 10-day mortality-associated risk factors were fever, neutropenia, ECOG 3/4, SOFA and fluoroquinolones as a protective factor. Pneumococcal bacteremia presented high mortality in cancer patients, with prognosis related to intrinsic host factors and infection episodes features. Fluoroquinolone treatment, a protective factor in 10-day mortality, has potential use for IPDs and severe community-acquired pneumonia in cancer patients.


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