scholarly journals Routine mammography: an opportunity for the diagnosis of chronic degenerative diseases? A cross-sectional study

2017 ◽  
Vol 50 (2) ◽  
pp. 82-89 ◽  
Author(s):  
Flávio Augusto Teixeira Ronzani ◽  
Filomena Maria Kirchmaier ◽  
Nathália Mussi Monteze ◽  
Edson José de Carvalho Magacho ◽  
Marcus Gomes Bastos ◽  
...  

Abstract Objective: The aim of this study was to evaluate breast arterial calcification (BAC) detected on routine mammography, analyzing its association with chronic degenerative disease. Materials and Methods: This was a cross-sectional study involving women treated at a specialized outpatient clinic for high-risk hypertension, diabetes, or chronic kidney disease, as well as volunteers who participated in a study to validate a method of screening for occult renal disease. A total of 312 patients between 40 and 69 years of age, with no history of breast cancer, all of whom had undergone routine mammography in the last two years, were included. The mammograms were analyzed by researchers who were unaware of the risk factors for BAC in each case. Results: The mean age was 55.9 ± 7.4 years, and 64.3% of the patients were white. The mean glomerular filtration rate was 41.87 ± 6.23 mL/min/1.73 m2. Seventy-one patients (22.8%) had BAC. We found that BAC was associated with advanced age, hypertension, diabetes, chronic kidney disease, and low glomerular filtration rate. In the multivariate analysis, advanced age and diabetes continued to be associated with BAC. The odds ratio for BAC was higher for all chronic diseases. Conclusion: The association of BAC with advanced age, hypertension, diabetes, chronic kidney disease, and low glomerular filtration rate should call the attention of radiologists. Therefore, the presence of BAC should be reported, and patients with BAC should be screened for those diseases.

Author(s):  
Francisco Veríssimo Veronese ◽  
Eduardo C. Gomes ◽  
Joana Chanan ◽  
Maicon A. Carraro ◽  
Eduardo G. Camargo ◽  
...  

AbstractThe Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation seems to correct the overdiagnosis of chronic kidney disease (CKD) provided by Modification of Diet in Renal Disease (MDRD) equation. However, this point has not been tested in some ethnic groups. This study investigated the performance of MDRD and CKD-EPI equations in South Brazilian individuals.This cross-sectional study included 354 individuals including healthy volunteers, diabetic and non-diabetic individuals with or without CKD. Glomerular filtration rate (GFR) was measured by theIn the group as a whole,CKD-EPI reduces GFR underestimation in individuals with GFRs >60, but still presents a quite low accuracy at this GFR range. Moreover, it tends to overestimate GFR in subjects with GFRs <60 mL/min/1.73 m


2020 ◽  
Author(s):  
Nipun de Silva ◽  
M.N.F. Mufeena ◽  
Gayathri Sam ◽  
Shashika Dayarathna ◽  
Deepthi Kumari ◽  
...  

Abstract Objectives: To compare carriage rates of Staphylococcus aureus in patients with and without chronic kidney disease (CKD) and identify associated factors. Results: We enrolled 64 CKD (A-1 = 13, A-2 = 17, A-3 = 34) and 56 non-CKD controls (B). Patients were categorized as: stage 5 CKD on haemodialysis (A-1), stage 5 CKD not on haemodialysis (A-2), renal transplant recipients with glomerular filtration rate > 60 ml/min (A-3) and those having chronic medical diseases with glomerular filtration rate > 60 ml/min/m2 (B). Median age = 57 years (range = 17–77). Nasal or axillary Staphylococcus aureus carriage was seen in 5 (38.5%), 2 (11.8%), 5 (14.7%) and 9 (16.1%) patients from A-1 to A-3 and B groups respectively. All isolated organisms were methicillin sensitive. Haemodialysis (p = 0.035) and antibiotic use in the preceding month (p = 0.02) were associated with carriage. Demographic factors and co-morbidities were not associated with carriage.


2016 ◽  
Vol 5 (3) ◽  
Author(s):  
Rahmat Hidayat ◽  
Syaiful Azmi ◽  
Dian Pertiwi

AbstrakAnemia merupakan salah satu masalah utama pada pasien penyakit ginjal kronik. Tinggi rendahnya laju filtrasi glomerulus mempengaruhi kejadian anemia pada penyakit ginjal kronik. Tujuan penelitian ini adalah mengidentifikasi hubungan kejadian anemia dengan penyakit ginjal kronik pada pasien yang dirawat di Bagian Penyakit Dalam tahun 2010. Penelitian yang dilakukan merupakan survei analitik dengan menggunakan design penelitian cross sectional study. Penelitian menggunakan data sekunder yang diambil dari sub bagian Rekam Medik (Medical Record) RSUP dr. M Djamil Padang dari Juni–Desember 2012 dengan jumlah sampel adalah 67 pasien penyakit ginjal kronik. Ditemukan angka kejadian anemia pada pasien penyakit ginjal kronik sebesar 98,5% dengan rata-rata kadar Hb sebesar 7,3 g/dl dan rata-rata laju filtrasi glomerulus adalah 8,81 ml/menit/1.73m2. Dari hasil uji korelasi Pearson diperoleh hasil adanya hubungan kejadian anemia dengan penyakit ginjal kronik di RSUP dr M Djamil Padang  dengan p = 0,00 (p < 0,05). Kesimpulan hasil penelitian ini adalah semakin rendah laju filtrasi glomerulus menunjukkan semakin rendah juga kadar hemoglobin pada pasien penyakit ginjal kronik.Kata kunci: anemia, penyakit ginjal kronik, laju filtrasi glomerulus AbstractAnemia is one of the major problems in patients with chronic kidney disease. High and low glomerular filtration rate affect the incidence of anemia in chronic kidney disease. The objective of this study was to identify the relationship  of anemia on patients with chronic kidney disease in the Internal Medicine. The type of this research was analytic studies using a cross sectional study research design from June–December 2012 . This study used secondary data taken from Medical Record department of dr. M. Djamil hospital  with  samples of the entire medical record is 67 persons chronic kidney disease patients in 2010. The result found the incidence of anemia in chronic kidney disease patients was 98.5%, with an average hemoglobin level at 7.3 g/dl and mean glomerular filtration rate was 8.81 ml /min/1.73m2. Pearson correlation of test results obtained by the result of the relationship of anemia on patients with chronic kidney disease at dr M Djamil Padang Hospital with p = 0.00 (p <0,05). The low rate of glomerular filtration rate also showed by the low level of hemoglobin in patients with chronic kidney disease    Keywords: anemia, chronic kidney disease, glomerular filtration rate


2019 ◽  
Vol 41 (2) ◽  
pp. 193-199
Author(s):  
Luciana Satiko Sawamura ◽  
Gabrielle Gomes de Souza ◽  
Juliana Dias Gonçalves dos Santos ◽  
Fabíola Isabel Suano-Souza ◽  
Anelise Del Vecchio Gessullo ◽  
...  

Abstract Objective: To describe the frequency of albuminuria in overweight and obese children and adolescents and to relate it to the severity of obesity, pubertal staging, associated morbidities and the glomerular filtration rate. Method: Cross-sectional study including 64 overweight and obese children and adolescents between 5 and 19 years of age. Data collected: weight, height, waist circumference and systemic arterial pressure. Laboratory tests: lipid profile; glycemia and insulin, used to calculate the Homeostasis Model Assessment (HOMA-IR); C-reactive protein; glutamic-pyruvic transaminase and albuminuria in an isolated urine sample (cutoff <30 mg/g). Creatinine was used to calculate the estimated glomerular filtration rate (eGFR, mL/min/1.73 m2). Results: The mean age was 11.6 ± 3.4 years, 32 (50%) and 29 (45.3%) were male and prepubertal. Forty-six (71.9%) had severe obesity. The frequency and median (min/max) of the observed values for albuminuria (> 30 mg/g) were 14 (21.9%) and 9.4 mg/g (0.70, -300.7 mg/g). The mean eGFR was 122.9 ± 24.7 mL/min/1.73 m2. There was no significant correlation between body mass index, pubertal staging, insulin and HOMA-IR with albuminuria values and neither with eGFR. Children with albuminuria tended to have higher values of diastolic blood pressure (75.0 ± 12.2 vs. 68.1 ± 12.4, p = 0.071). Conclusion: Albuminuria, although frequent in children and adolescents with obesity, was not associated with other morbidities and the glomerular filtration rate in these patients.


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