scholarly journals BRAZILIAN CONSENSUS ON INCIDENTAL GALLBLADDER CARCINOMA

2020 ◽  
Vol 33 (1) ◽  
Author(s):  
Felipe Jose F COIMBRA ◽  
Orlando Jorge M TORRES ◽  
Ruslan ALIKHANOV ◽  
Anil AGARWAL ◽  
Patrick PESSAUX ◽  
...  
Keyword(s):  
Lymph Node ◽  
Minimally Invasive ◽  
Gallbladder Cancer ◽  
Gallbladder Carcinoma ◽  
Preoperative Evaluation ◽  
Lymph Node Biopsy ◽  
R0 Resection ◽  
Final Report ◽  
Incidental Gallbladder Cancer ◽  
Agreement Assessment

ABSTRACT Background: Incidental gallbladder cancer is defined as a cancer discovered by histological examination after cholecystectomy. It is a potentially curable disease. However, some questions related to their management remain controversial and a defined strategy is associated with better prognosis. Aim: To develop the first evidence-based consensus for management of patients with incidental gallbladder cancer in Brazil. Methods: Sixteen questions were selected, and 36 Brazilian and International members were included to the answer them. The statements were based on current evident literature. The final report was sent to the members of the panel for agreement assessment. Results: Intraoperative evaluation of the specimen, use of retrieval bags and routine histopathology is recommended. Complete preoperative evaluation is necessary and the reoperation should be performed once final staging is available. Evaluation of the cystic duct margin and routine 16b1 lymph node biopsy is recommended. Chemotherapy should be considered and chemoradiation therapy if microscopically positive surgical margins. Port site should be resected exceptionally. Staging laparoscopy before reoperation is recommended, but minimally invasive radical approach only in specialized minimally invasive hepatopancreatobiliary centers. The extent of liver resection is acceptable if R0 resection is achieved. Standard lymph node dissection is required for T2 tumors and above, but common bile duct resection is not recommended routinely. Conclusions: It was possible to prepare safe recommendations as guidance for incidental gallbladder carcinoma, addressing the most frequent topics of everyday work of digestive and general surgeons.

Scalene lymph node biopsy in the preoperative evaluation of patients with recurrent cervical cancer

1989 ◽  
Vol 33 (3) ◽  
pp. 332-334 ◽  
Author(s):  
Alberto Manetta ◽  
Edward S. Podczaski ◽  
James E. Larson ◽  
Koen De Geest ◽  
Rodrigue Mortel
Keyword(s):  
Cervical Cancer ◽  
Lymph Node ◽  
Preoperative Evaluation ◽  
Lymph Node Biopsy ◽  
Recurrent Cervical Cancer ◽  
Node Biopsy

scholarly journals Role of routine 16b1 lymph node biopsy in the management of gallbladder cancer: an analysis

HPB ◽  
2014 ◽  
Vol 16 (3) ◽  
pp. 229-234 ◽  
Author(s):  
Anil K. Agarwal ◽  
Raja Kalayarasan ◽  
Amit Javed ◽  
Puja Sakhuja
Keyword(s):  
Lymph Node ◽  
Gallbladder Cancer ◽  
Lymph Node Biopsy ◽  
Node Biopsy

scholarly journals Incidental gallbladder carcinoma in regional Clinical Centre

2010 ◽  
Vol 57 (2) ◽  
pp. 95-97 ◽  
Author(s):  
F. Mitrovic ◽  
G. Krdzalic ◽  
N. Musanovic ◽  
H. Osmic
Keyword(s):  
Survival Rate ◽  
Gallbladder Cancer ◽  
Gallbladder Carcinoma ◽  
Open Cholecystectomy ◽  
Squamous Carcinoma ◽  
Radical Resection ◽  
Significant Difference ◽  
Clinical Centre ◽  
Incidental Gallbladder Cancer ◽  
Surgery Department

Background and Objectives: The aim of the study is to assess the characteristics, TNM stage and survival rate of incidental gallbladder carcinoma in patients who underwent open cholecystectomy in regional clinical centre. Patients and Methods: We retrospectively analyzed all consecutive cholecystectomies during four years period in surgery department and determined incidence, pathological stage and survival rate of incidental gallbladder cancer. Demographics data, surgical management, adjuvant therapy, death or last follow-up. We compared common characteristics and survival between pTis,1ab and pT2-3 groups of patients who underwent cholecytectomy alone. Results: Gallbladder carcinoma was diagnosed in 21 patients of 3007 cholecystectomies (0.69%). The most of patients had abdominal pain, cholelithiasis and fever. Postoperative pathology showed 20 adenocarcinomas and 1 squamous carcinoma. Seven cases were stage I, 7 stage II, 5 stage III. There was no patient in pT4 stage. The mean age was 60.6 ye-ars range (43-75). The 4 patients with pTis and 3 patients with pT1 had a 5-year survival rate of 100%. Patients with pT2-3 GBC had 5-year survival rate 8.34%. We noticed significant difference between those two cancer groups p<0.001. Conclusions: The incidence of incidental gallbladder cancer in this study was 0.69%. The pT-stage is very important factor in overall survival those patients. All cases of pT2-3 incidental GBC should be considered for extended radical resection after cholecystectomy alone.

scholarly journals Magnetic-Guided Axillary UltraSound (MagUS) Sentinel Lymph Node Biopsy and Mapping in Patients with Early Breast Cancer. A Phase 2, Single-Arm Prospective Clinical Trial

Cancers ◽  
2021 ◽  
Vol 13 (17) ◽  
pp. 4285
Author(s):  
Allan Jazrawi ◽  
Eirini Pantiora ◽  
Shahin Abdsaleh ◽  
Daniel Vasiliu Bacovia ◽  
Staffan Eriksson ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Minimally Invasive ◽  
Early Breast Cancer ◽  
Neoadjuvant Treatment ◽  
Superparamagnetic Iron Oxide ◽  
Standard Of Care ◽  
Lymph Node Biopsy ◽  
Axillary Ultrasound

Lymph Node Dissection (SLND) is standard of care for diagnosing sentinel lymph node (SLN) status in patients with early breast cancer. Study aim was to determine whether the combination of Superparamagnetic iron oxide nanoparticles (SPIO) MRI-lymphography (MRI-LG) and a Magnetic-guided Axillary UltraSound (MagUS) with biopsy can allow for minimally invasive, axillary evaluation to de-escalate surgery. Patients were injected with 2 mL of SPIO and underwent MRI-LG for SN mapping. Thereafter MagUS and core needle biopsy (CNB) were performed. Patients planned for neoadjuvant treatment, the SLN was clipped and SLND was performed after neoadjuvant with the addition of isotope. During surgery, SLNs were controlled for signs of previous biopsy or clip. The primary endpoint was MagUS SLN detection rate, defined as successful SLN detection of at least one SLN of those retrieved in SLND. In 79 patients, 48 underwent upfront surgery, 12 received neoadjuvant and 19 had recurrent cancer. MagUS traced the SLN in all upfront and neoadjuvant cases, detecting all patients with macrometastases (n = 10). MagUS missed only one micrometastasis, outperforming baseline axillary ultrasound AUS (AUC: 0.950 vs. 0.508, p < 0.001) and showing no discordance to SLND (p = 1.000). MagUS provides the niche for minimally invasive axillary mapping that can reduce diagnostic surgery.

Breast sentinel lymph node biopsy with imaging towards minimally invasive surgery

2017 ◽  
Vol 62 (6) ◽  
pp. 547-555 ◽  
Author(s):  
Fredrick Johnson Joseph ◽  
Alexander van Oepen ◽  
Michael Friebe
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Minimally Invasive ◽  
Single Photon ◽  
Photon Emission ◽  
Lymph Node Biopsy ◽  
Emission Computed Tomography ◽  
Imaging Methods ◽  
Node Biopsy

AbstractBreast sentinel lymph nodes are still commonly assessed through complete lymph node dissections, which is a time-consuming and radical approach because the nodes are difficult to identify. To prevent false diagnosis and achieve accurate results, minimally invasive, image-guided procedures are applied and constantly improved. The purpose of this paper is to present the currently used imaging modalities ultrasound, fluorescence, single-photon emission computed tomography (SPECT), magnetic resonance imaging (MRI) and hybrid imaging methods and comparing their effectiveness for breast sentinel lymph node biopsy. A definition for an ideal imaging system combining efficient minimally invasive techniques with workflow considerations is also discussed. As a conclusion, upcoming imaging methods and their future outlook with areas of advancement are presented.

scholarly journals Case Report: Ischaemic appendicitis post mesenteric biopsy

F1000Research ◽  
2016 ◽  
Vol 5 ◽  
pp. 3
Author(s):  
Marianna Zukiwskyj ◽  
June Tun ◽  
Shashank Desai
Keyword(s):  
Abdominal Pain ◽  
Case Report ◽  
Lymph Node ◽  
Minimally Invasive ◽  
Lymph Node Biopsy ◽  
Minimally Invasive Approach ◽  
Invasive Approach ◽  
Common Indication ◽  
Mesenteric Lymph ◽  
Node Biopsy

A common indication for laparoscopic mesenteric lymph node biopsy is to provide a tissue diagnosis in the absence of palpable peripheral nodes via a minimally invasive approach.  There are no reports to date of ischaemia to the appendix as a complication of this procedure.   We report the case of a 34-year-old lady who underwent a mesenteric biopsy for a lesion found incidentally on CT to investigate longstanding abdominal pain, and 2 days later required an appendicectomy for ischaemic appendicitis.

scholarly journals Residual disease in lymph nodes has no influence on survival in patients with incidental gallbladder cancer – institution experience with literature review

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Mihajlo Đokic ◽  
Urban Stupan ◽  
Sabina Licen ◽  
Blaz Trotovsek
Keyword(s):  
Lymph Node ◽  
Survival Rate ◽  
Lymph Nodes ◽  
Gallbladder Cancer ◽  
Lymph Node Metastases ◽  
Residual Disease ◽  
Treatment Strategies ◽  
Node Metastases ◽  
Incidental Gallbladder Cancer

Abstract Background A better appreciation of the course and factors that influence incidental gallbladder cancer (iGBC) is needed to develop treatment strategies aimed to improve outcomes. The purpose of the study was to determine the influence of residual disease in the liver and lymph nodes on overall survival in re-resected patients with iGBC. Patients and methods Patients undergoing radical re-resection for iGBC from January 2012 to December 2018 were retrospectively identified. Patients with a 5-year follow-up and submitted to complete resection with stage I, II and III disease were analysed. The influence of residual disease (RD) in liver and lymph nodes on survival was assessed using the Kaplan-Meier curves. In addition, the rest of the group was assessed based on type of primary/secondary procedure, number of harvested lymph nodes and RD in liver and/or lymph nodes. Results In this retrospective study 48 out of 58 (83%) patients underwent re-resection. Among the group with a 5-year follow-up (re-operation between 2012–2014), 22 patients out of 28 (79%) were re-resected. Survival analysis showed that patients with no RD in the liver and lymph nodes had statistically significant better 5-year survival than those with RD. Comparing 5-year survival rate in patients with RD in the liver or lymph nodes against no RD group, patients with RD in the liver had statistically significantly worse 5-year survival, while lymph node metastases did not show any statistically significant different in 5-year survival. Besides, a statistically significant better prognosis was found in stage II disease compared to stage III, as expected. Conclusions The most important predictors of a 5-year survival in our study were RD in liver and stage of the disease. Lymph node metastases did not have any impact on the overall 5-year survival rate.

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