scholarly journals Early diagnosis of atherosclerosis with panoramic radiographs: a review

2016 ◽  
Vol 15 (4) ◽  
pp. 302-307
Author(s):  
Daiane Landim Borba ◽  
◽  
Ulisses Vilela Hipólito ◽  
Yamba Carla Lara Pereira

Abstract Carotid artery disease has been linked with cerebral vascular accident, also known as stroke, cerebral hemorrhage, or cerebral ischemia. It is caused by narrowing or obstruction of arteries in the neck (the carotid arteries) that are responsible for transporting blood from the aorta to the brain. Panoramic radiographs are used in dentistry to show both dental arches as a supplement to the clinical dental examination. The objective of this study is to highlight the importance of panoramic radiographs for diagnosis of arterial disease, by means of a bibliographic review. The PubMed database was searched using the keywords “atherosclerosis” and “panoramic”, with the filters “last 5 years” and “humans”. Twenty articles were identified, six of which were chosen for this study because they were open access. The review concluded that panoramic radiographs enable early diagnosis of carotid artery calcification, resulting in earlier interventions, and offer an accessible cost.

2016 ◽  
Vol 72 (1) ◽  
Author(s):  
Giusy Sirico ◽  
Lucrezia Spadera ◽  
Mario De Laurentis ◽  
Gregorio Brevetti

Although during the last decade there have been great advances in our knowledge of the epidemiology and pathophysiology of multi-district atherosclerotic disease, little is known about the association between peripheral arterial disease and carotid artery disease. This review was conceived to cast some light on this topic, paying special attention to inflammation which plays a pivotal role in atherosclerosis. An aspect of pathophysiologic and clinical relevance is that the coexistence of carotid disease is more frequent in peripheral arterial disease than in coronary artery disease, not only in terms of carotid stenosis, but also with respect to the presence of hypoechoic unstable plaque. These latter plaques present a large infiltration of macrophages and are associated to high levels of inflammatory markers. In particular, the greater prevalence of hypoechoic carotid plaques in peripheral arterial disease compared to patients with carotid artery disease was poorly related to classic risk factors, but showed an independent association with an increased number of leukocyte and neutrophil cells, which are reliable markers of inflammation. The greater prevalence of hypoechoic unstable carotid plaques could explain why peripheral arterial disease portends higher risk of stroke than coronary artery disease.


1989 ◽  
Vol 76 (2) ◽  
pp. 221-228 ◽  
Author(s):  
M. V. Monsalve ◽  
R. Young ◽  
S. A. Wiseman ◽  
S. Dhamu ◽  
J. T. Powell ◽  
...  

1. We have determined the frequency of DNA polymorphisms of the human apolipoprotein AI-CIII-AIV gene cluster, detected with XmnI, PstI, and PvuII, in a group of patients with peripheral arterial disease. 2. Of the patients, 81 had no evidence of disease in the coronary and carotid arteries, 73 had coronary artery disease but no evidence of carotid artery disease, 25 patients had carotid artery disease but no evidence of coronary artery disease, and 38 had both coronary and carotid artery disease. 3. Levels of triacylglycerol, cholesterol, apolipoprotein B and apolipoprotein AI were not significantly different between the four patient groups. 4. The frequencies of the alleles for the apolipoprotein AI-CIII-AIV polymorphisms, detected with XmnI, PstI and PvuII, did not differ significantly in the patient groups when compared with a sample of clinically well normolipidaemic individuals also from a London population. 5. All five patients with the XmnI genotype we designate X2X2 had high levels of cholesterol, apolipoprotein B and apolipoprotein AI. 6. Patients with the rare VB2 allele of the apolipoprotein CIII-AIV restriction fragment length polymorphism had lower levels of cholesterol, acylglycerol and significantly lower levels of serum apolipoprotein. 7. Our observations suggest that variation in the apolipoprotein AI-CIII-AIV gene cluster may not be contributing significantly to the development of peripheral arterial disease, but variation associated with some of the restriction fragment length polymorphisms may be involved in determining levels of cholesterol- and apolipoprotein-B-containing lipoproteins.


2020 ◽  
pp. 106-130
Author(s):  
Louis R. Caplan

Abstract: This chapter describes Fisher’s career in Montreal (1950–1954) and his ultimate transfer to Boston. His family life, studies, accomplishments, and writings during this period are also described. Highlighted are his discoveries about carotid artery disease, transient loss of vision, transient episodes of brain ischemia, lacunar brain infarction and its mechanisms, brain embolism, and the distribution of atherosclerosis within the arteries that supply the brain. While in Montreal, Fisher became a productive researcher. His work on carotid artery disease and temporary episodes of eye and brain ischemia gained him widespread recognition. However, he eventually decided that the future of his stroke work was far brighter in Boston than if he stayed in Montreal, and so he eventually decided to return to Boston.


2005 ◽  
Vol 120 (2) ◽  
pp. 93-97 ◽  
Author(s):  
S H Liyanage ◽  
A Singh ◽  
P Savundra ◽  
A Kalan

Pulsatile tinnitus is an uncommon otological symptom. Objective pulsatile tinnitus has numerous causes, including benign intracranial hypertension, glomus tumours and atherosclerotic carotid artery disease. History and physical examination can give important information as to the underlying diagnosis. Radiographic evaluation is essential in all patients with pulsatile tinnitus. Many patients have a treatable underlying aetiology. Early diagnosis and appropriate intervention may save patients from unnecessary morbidity.


Author(s):  
A. G. Lynch ◽  
M. T. Walsh

Modern surgical treatment of arterial disease is moving towards minimally invasive procedures, as the benefits are numerous. However, one area that is resisting this trend is the treatment of carotid artery disease. For the past number of decades carotid endarterectomy surgery has been referred to as the “gold standard” in the treatment of carotid artery disease. However, in recent year’s carotid angioplasty and stenting (CAS) has emerged to challenge carotid endarterectomy surgery (CES) as a viable alternative for the prevention of strokes. However uptake of this procedure has been hindered due to the peri-operative complications associated with the treatment. During this procedure blood flow in one of the internal carotid arteries supplying blood to the brain is interrupted for a period of time. However, it has been shown that not all patients can accommodate this interruption. Qureshi et al. suggests that ischemic neurological deficits occur in 3 to 13% of patients as a result of hemodynamic compromise.


2020 ◽  
Vol 4 (3) ◽  
pp. 101
Author(s):  
Dwi Putri Wulansari ◽  
Farina Pramanik

Objectives: This review aimed to understand the radiographic features of carotid artery atheroma on panoramic radiographs as an early diagnosis of atherosclerosis. Literature Review: Carotid artery calcification is caused by a plaque known as an atheroma. Atheroma is a plaque composed of lipids and rich in calcium. If atheroma formation in the carotid arteries increases, it would cause stenosis of the blood vessels and increase the risk of stroke. On panoramic radiographs, carotid artery atheroma appears as a heterogeneous radiopaque image with an irregular shape and well-defined borders. Radiopaque image located inferior to the angle of the mandible, close to the cervical spine (C3-C5) and above the hyoid bone. Conclusion: Incidental findings on panoramic radiograph could be an initial reference for further examination and evaluation of atherosclerosis.


Sign in / Sign up

Export Citation Format

Share Document