Clinical application of adhesive systems - a critical review: biomimetic approach

The various functions and clinical applications of adhesive systems have become a fundamental part of restorative treatment. The biggest challenge for such systems is to provide adequate adhesion to the different tissues, which can be very diverse in nature. When choosing the appropriate adhesive system, the dentist should be familiar with the origin, composition, action mechanism and method of application of each system. The commercially available products and their high technical status have made it possible for the clinician to develop a philosophy of maximum tissue preservation, optimized esthetics, up-to-date concepts and procedures and full function of the restored element, compatible with biomimetic theory. The literature describes the superior qualities of results obtained with three-step total etching adhesives and the use of chlorhexidine as a factor to increase longevity. Future perspectives include the use of ethanol, inactivating agents of enzymes released in the adhesive process and the action of agents that act upon the dentin matrix.

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Innovative Adhesive Systems for Dental Giomer Restorations

Revista de Chimie ◽

10.37358/rc.18.10.6605 ◽

2018 ◽

Vol 69 (10) ◽

Author(s):

Ioana Hodisan ◽

Cristina Prejmerean ◽

Tinca Buruiana ◽

Doina Prodan ◽

Loredana Colceriu ◽

...

Keyword(s):

Acrylic Acid ◽

Itaconic Acid ◽

Adhesive System ◽

Adhesive Systems ◽

Substantial Agreement ◽

Dye Penetration ◽

Strong Adhesion ◽

Innovative Materials ◽

Dental Applications

The aim of this work was to reduce microleakage in giomer restorations by using innovative materials in both adhesive systems and light-cured dental giomer. Two adhesive systems with different primers were investigated. The innovative compounds in the primers were acrylic acid (AA)/itaconic acid (IA) copolymer modified with methacrylic groups and AA/IA/N-acryloyl-L-leucine copolymer grafted with methacrylic groups. In addition, the investigated new giomer G contains a pre-reacted glass based on the latter copolymer. The commercial Beautifil II giomer and the FL-Bond II adhesive system were used for comparison. Microleakage was evaluated by determining the scores and percentages of dye penetration lengths after thermocycling of a series of light-cured dental giomer restorations performed on 42 premolars extracted for orthodontic reasons. A lower microleakage value was recorded for the adhesive system containing the AA/IA/N-acryloyl-L-leucine copolymer grafted with methacrylic groups than for the commercial adhesive, which was in substantial agreement with SEM and AFM investigations. In this case, remarkable dentin sealing and a strong adhesion at the giomer restoration�tooth interface was observed, and the innovative adhesive was proven to be promising for dental applications.

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Trans-dentinal Stimulation of Tertiary Dentinogenesis

Advances in Dental Research ◽

10.1177/08959374010150011301 ◽

2001 ◽

Vol 15 (1) ◽

pp. 51-54 ◽

Cited By ~ 64

Author(s):

A.J. Smith ◽

P.E. Murray ◽

A.J. Sloan ◽

J.B. Matthews ◽

S. Zhao

Keyword(s):

Growth Factors ◽

Tissue Injury ◽

Careful Consideration ◽

Active Components ◽

Restorative Treatment ◽

Cellular Events ◽

Dentin Matrix ◽

Dentin Thickness ◽

Tertiary Dentinogenesis ◽

Stimulation Of

Trans-dentinal stimulation of tertiary dentinogenesis has long been recognized, and has traditionally been ascribed to diffusion of irritant substances arising during injury and restorative treatment. Identification of bio-active components, especially growth factors including TGF-βs, sequestered within dentin matrix provides a new explanation for cellular signaling during tertiary dentinogenesis. Both isolated dentin matrix components and pure growth factors (TGF-βs) have been shown to signal cellular events leading to reactionary and reparative tertiary dentinogenesis. Release of these bio-active components from dentin matrix may arise during carious attack and other injury to the tissue, and also during subsequent surgical intervention and restoration of the tooth. Both cavity-conditioning agents and leaching from restorative materials may contribute to release of these components. Distance of diffusion, as determined by cavity residual dentin thickness, and other restorative parameters may influence the signaling process after release of these components. Careful consideration of the interplay between tissue injury and surgical and restorative material factors is required for optimum exploitation of the exquisite regenerative capacity of dentin-pulp for more biological approaches to clinical treatment of dental disease.

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Quantitative evaluation of microleakage in class V cavities using one-bottle and self-etching adhesive systems

Brazilian Oral Research ◽

10.1590/s1806-83242004000300014 ◽

2004 ◽

Vol 18 (3) ◽

pp. 253-259 ◽

Cited By ~ 2

Author(s):

Fabiana Mantovani Gomes França ◽

Flávio Henrique Baggio Aguiar ◽

Alex José Souza dos Santos ◽

José Roberto Lovadino

Keyword(s):

Methylene Blue ◽

In Vitro Study ◽

Adhesive System ◽

Acid Etching ◽

Single Bond ◽

Adhesive Systems ◽

Class V ◽

Bonding System ◽

Root Dentin

The aim of this in vitro study was to evaluate quantitatively the microleakage in class V cavities restored with one-bottle and self-etching adhesive systems with and without previous acid etching. Two one-bottle adhesive systems (Single Bond and Prime & Bond 2.1) and one self-etching adhesive system (Clearfil Mega Bond) were used in this study. One hundred and twenty sound human premolar teeth were randomly divided into 6 groups, and 20 class V restorations were prepared in the root dentin to test each bonding system. Each bonding system was used with and without acid etching. Specimens were prepared, dyed with 2% methylene blue, sectioned, triturated, and evaluated with an absorbance spectrophotometer test in order to quantify the infiltrated dye. Results were statistically evaluated by ANOVA and Tukey-Kramer test. No statistically significant differences were found among the adhesive systems when no etching agent was used. However, the Single Bond adhesive system showed statistically significant lower microleakage means than Clearfil Mega Bond and Prime & Bond 2.1 when 37% phosphoric acid was used. Single Bond and Clearfil Mega Bond adhesive systems presented similar behavior when the manufacturers' instructions were followed.

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Morphology and thickness of the diffusion of resin through demineralized or unconditioned dentinal matrix

Pesquisa Odontológica Brasileira ◽

10.1590/s1517-74912002000200004 ◽

2002 ◽

Vol 16 (2) ◽

pp. 115-120 ◽

Cited By ~ 14

Author(s):

César Augusto Galvão Arrais ◽

Marcelo Giannini

Keyword(s):

Adhesive System ◽

Adhesive Systems ◽

Hybrid Layer ◽

Human Teeth ◽

Bonding Agents ◽

Mean Values ◽

Dentin Bonding ◽

Occlusal Surfaces ◽

The One ◽

Bonding Systems

The formation of a hybrid layer is the main bonding mechanism of current dentin-bonding systems. This study evaluated the morphology and thickness of the resin-infiltrated dentinal layer after the application of adhesive systems. The dentin-bonding agents were evaluated on flat dentinal preparations confected on the occlusal surfaces of human teeth. The test specimens were prepared and inspected under scanning electron microscopy at a magnification of X 2,000. The adhesive systems were responsible for different hybrid layer thicknesses (p < 0.05), and the mean values were: for Scotchbond MP Plus (SM), 7.41 ± 1.24mum; for Single Bond (SB), 5.55 ± 0.82mum; for Etch & Prime 3.0 (EP), 3.86 ± 1.17mum; and for Clearfil SE Bond (CB), 1.22 ± 0.45mum. The results suggest that the conventional three-step adhesive system (SM) was responsible for the thickest hybrid layer, followed by the one-bottle adhesive (SB). The self-etching adhesives, EP and CB, produced the formation of the thinnest hybrid layers.

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Shear Bond Strength of Different Adhesive Systems to Primary Dentin and Enamel

Journal of Clinical Pediatric Dentistry ◽

10.17796/jcpd.31.1.2436up85l810667h ◽

2007 ◽

Vol 31 (1) ◽

pp. 35-40 ◽

Cited By ~ 7

Author(s):

Carla Miranda ◽

Luiz Henrique Maykot Prates ◽

Ricardo de Souza Vieira ◽

Maria Cristina Marino Calvo

Keyword(s):

Bond Strength ◽

Failure Mode ◽

Shear Bond Strength ◽

Adhesive System ◽

Mode Analysis ◽

Single Bond ◽

Adhesive Systems ◽

Mean Values ◽

Failure Mode Analysis ◽

Distal Direction

The aims of this study were to evaluate the shear bond strength (SBS) of four adhesive systems applied to primary dentin and enamel and verify, after SBS testing, the failure mode of the adhesive interface. Sixty extracted sound primary molars were selected and crowns were sectioned in a mesial-distal direction. Specimens were randomly assigned into two groups (adhesion to enamel and adhesion to dentin) and then subdivided into four subgroups according to the adhesive system (n=15): Scotchbond Multi-Purpose (SMP) – Single Bond (SB) – Clearfil SE Bond (and Adper Prompt LPop (APL) – SBS tests were performed and the obtained values were statistically analyzed using ANOVA and Tukey tests (p<0.05). The failure mode analysis was performed with a Scanning Electron Microscope (XL-30, Philips). SBS mean values on enamel were [MPa (SD)]: SMP – 27.89 (7.49); SB – 23.92 (8.8); CSB – 24.36 (6.69); APL – 25.96 (4.08); and on dentin: SMP – 17.29 (4.25); SB – 18.2 (8.74); CSB – 16.13 (7.14); APL – 6.04 (3.35). The predominant failure mode was cohesive (primarily of the bonding agent). On enamel SBS was statistically similar for all four adhesives. On dentin SBS of APL was lower than the other tested adhesives.

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Nd:YAG laser influence on the hybridization quality, employing total-etching or self-etching adhesives: sem analysis

Brazilian Dental Science ◽

10.14295/bds.2016.v19i1.1174 ◽

2016 ◽

Vol 19 (1) ◽

pp. 34

Author(s):

Andressa Da Silva Kuwana ◽

Ivan Balducci ◽

Leily Macedo Firoozmand ◽

Daphne Camara Barcellos ◽

Sérgio Eduardo de Paiva Gonçalves

Keyword(s):

Nd:Yag Laser ◽

Statistical Tests ◽

Adhesive System ◽

Positive Influence ◽

Sem Analysis ◽

Ratio Test ◽

Hybrid Layer ◽

Cervical Portion ◽

Total Etching

Background: The application of Nd:YAG laser on dentin with the adhesive system non-polymerized can influenced the quality of hybrid layer formed. Objectives: The aim of this study is to assess through analysis by scanning electronic microscopy (SEM), the Nd:YAG laser influence on the hybridization quality, using conventional Adper Single Bond (SB) or self-etching Clearfil SE Bond-Kuraray (CSEB) adhesives. Methods: Nine bovine incisors were treated on their incisal with SB and with CSEB in their cervical portion. They were divided into 3 groups with 6 specimens in each and treated as follows; G1- adhesive system and polymerization; G2- adhesive system, laser (60mJ/pulse) and polymerization; G3- adhesive system, laser (140mJ/pulse) and polymerization. All samples were restored with composite resin (Filtek Z350-3M). The thickness, the presence of failures (gap/porosity) and tags/microtags in the hybrid layer were analyzed using the SEM. The data were submitted to ANOVA and Tukey statistical tests 5%. Results: The highest average of hybrid layer thickness (1.89±0.15) was observed for G3 and the smallest was observed for G1-CSEB (1.36±0.14). The multiple comparison of ratio test showed that the smallest prevalence of failures was for G3-CSEB and the best performance for the presence of tags/microtags was found for G2-SB. Conclusion: Independent of the adhesive system used, the Nd:YAG laser, according to the parameter applied, had a positive influence on the hybridization quality.

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Bond strength to dentin of total-etch and self-etch adhesive systems

RGO - Revista Gaúcha de Odontologia ◽

10.1590/1981-8637201400040000022648 ◽

2014 ◽

Vol 62 (4) ◽

pp. 365-370 ◽

Cited By ~ 1

Author(s):

Ricardo Alves dos SANTOS ◽

Eliane Alves de LIMA ◽

Mônica Maria de Albuquerque PONTES ◽

Alexandre Batista Lopes do NASCIMENTO ◽

Marcos Antônio Japiassú Resende MONTES ◽

...

Keyword(s):

Bond Strength ◽

Testing Machine ◽

Adhesive System ◽

Single Bond ◽

Adhesive Systems ◽

Healthy Human ◽

Universal Testing ◽

Stereo Microscope ◽

Diamond Disc ◽

Self Etch

OBJECTIVE: To assess the bond strength to dentin of the Single Bond (3M ESPE) and XP Bond (Dentsply) total-etch and Adper SE Plus (3M ESPE) self-etch adhesive systems. METHODS: Fifteen healthy human third molars were randomly allocated across three different groups of five teeth each according to the adhesive system. The occlusal portion of each tooth was removed under refrigeration using a flexible diamond disc (EXTEC, Enfield, CT, USA) down to an area of dentin that did not reveal enamel, as confirmed under a 40X stereo microscope (Ramsor, São Paulo, Brazil). A standardized smear layer was created with #600 grit silicon-carbide paper. The adhesive systems were applied as per manufacturer recommendations, with the exception of the Adper SE Plus system, which was triple-polymerized. Composite resin blocks (5 mm) were placed on the dentin surface. The specimens were stored in distilled water for 24 hours at 37ºC. Using a flexible diamond disc (EXTEC, Enfield, CT, USA), toothpick-like specimens with an adhesive area of less than 1 mm² were obtained. A microtensile bond test was then carried out using a universal testing machine (KRATOS) with a crosshead speed of 0.5 mm/min. Analysis of variance (ANOVA) and Tukey's test were used for comparisons. RESULTS: The bond strength values obtained with each adhesive system were as follows: XP Bond, 96.24 MPa; Adper Single Bond, 72.39 MPa; Adper SE Plus, 49.91 MPa. CONCLUSION: In terms of bond strength to dentin, conventional adhesives outperform self-etching systems.

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Effect of one-bottle adhesive systems on the fluoride release of a resin-modified glass ionomer

Journal of Applied Oral Science ◽

10.1590/s1678-77572004000100003 ◽

2004 ◽

Vol 12 (1) ◽

pp. 12-17 ◽

Cited By ~ 1

Author(s):

Linda Wang ◽

Marília Afonso Rabelo Buzalaf ◽

Maria Teresa Atta

Keyword(s):

Statistical Difference ◽

Glass Ionomer Cement ◽

Adhesive System ◽

Fluoride Release ◽

Glass Ionomer Cements ◽

Glass Ionomer ◽

Adhesive Systems ◽

Resin Modified Glass Ionomer ◽

The One ◽

In The Beginning

A dhesive systems associated to resin-modified glass ionomer cements are employed for the achievement of a higher bond strength to dentin. Despite this benefit, other properties should not be damaged. This study aimed at evaluating the short-time fluoride release of a resin-modified glass ionomer cement coated with two one-bottle adhesive systems in a pH cycling system. Four combinations were investigated: G1: Vitremer (V); G2: Vitremer + Primer (VP); G3: Vitremer + Single Bond (VSB) and G4: Vitremer + Prime & Bond 2.1 (VPB). SB is a fluoride-free and PB is a fluoride-containing system. After preparation of the Vitremer specimens, two coats of the selected adhesive system were carefully applied and light-cured. Specimens were immersed in demineralizing solution for 6 hours followed by immersion in remineralizing solution for 18 hours, totalizing the 15-day cycle. All groups released fluoride in a similar pattern, with a greater release in the beginning and decreasing with time. VP showed the greatest fluoride release, followed by V, with no statistical difference. VSB and VPB released less fluoride compared to V and VP, with statistical difference. Regardless the one-bottle adhesive system, application of coating decreased the fluoride release from the resin-modified glass ionomer cements. This suggests that this combination would reduce the beneficial effect of the restorative material to the walls around the restoration.

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Shear Strength of Brackets Bonded with Universal Adhesive Containing 10-MDP after 20,000 Thermal Cycles

International Journal of Dentistry ◽

10.1155/2020/4265601 ◽

2020 ◽

Vol 2020 ◽

pp. 1-7

Author(s):

Mariana Almeida Mello Proença ◽

Karime Tavares Lima da Silva ◽

Alisson Costa e Silva ◽

Edilausson Moreno Carvalho ◽

José Bauer ◽

...

Keyword(s):

Bond Strength ◽

Shear Bond Strength ◽

Dental Enamel ◽

Adhesive System ◽

Test Machine ◽

Adhesive Systems ◽

Thermal Cycles ◽

Universal Adhesive ◽

Adhesive Remnant Index ◽

One Way Anova

Objectives. The aim of this study was to evaluate the shear bond strength of metal brackets bonded with different universal adhesive systems containing 10-MDP and Transbond Plus Self Etching Primer after 20,000 thermal cycles. Materials and Methods. A total of 130 sound bovine teeth were used, which are divided into 5 groups (n = 26) according to the adhesive system used: All-Bond Universal (Bisco), Ambar Universal (FGM), Clearfil Universal Bond (Kuraray), Single Bond Universal (3M/ESPE), and Transbond Plus SEP (3M/ESPE) as control. The adhesives were applied for 20 seconds and bonded with a resin Transbond XT (3M/ESPE). After this, the teeth were submitted to 20,000 cycles at 5°C and 55°C. Afterwards, the shear bond strength test was performed in a universal test machine (Instron 3342). The adhesive remnant index (ARI) was evaluated under a stereomicroscope at 10x magnification and scanning electronic microscopy (SEM, Hitachi 3030). The shear bond strength data were submitted to One-Way ANOVA (α = 0.05) and the ARI to the Kruskal–Wallis test (α = 0.05). Results. Statistical analysis showed that the universal adhesive systems presented mean shear bond strength values similar to Transbond Plus SEP (p<0.05). The universal adhesive presented similar ARI values among them but differed from those of Transbond Plus SEP (p<0.001). Transbond Plus SEP presented a high ARI value when compared with the universal adhesive systems and high demineralization of enamel. Conclusions. The results show that universal adhesive systems may be used for bonding metal brackets if the orthodontist wants to maintain dental enamel health.

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Influence of Thermal and Mechanical Load Cycling on Microtensile Bond Strengths of Total and Self-etching Adhesive Systems

Operative Dentistry ◽

10.2341/05-20 ◽

2006 ◽

Vol 31 (2) ◽

pp. 240-247 ◽

Cited By ~ 25

Author(s):

F. H. O. Mitsui ◽

A. R. Peris ◽

A. N. Cavalcanti ◽

G. M. Marchi ◽

L. A. F. Pimenta

Keyword(s):

Bond Strength ◽

Clinical Relevance ◽

Mechanical Load ◽

Adhesive System ◽

Adhesive Systems ◽

System Type ◽

Load Cycling ◽

Bond Strengths

Clinical Relevance Bond strength is affected by the combination of thermal and mechanical load cycling. However, results vary greatly with the number of mechanical cycles and adhesive system type (total or self-etching).

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