scholarly journals Late-onset neonatal sepsis in preterm infants with birth weight under 1.500 g

2015 ◽  
Vol 36 (4) ◽  
pp. 84-89 ◽  
Author(s):  
Stella Marys Rigatti Silva ◽  
Giordana de Cássia Pinheiro da Motta ◽  
Cristiane Raupp Nunes ◽  
Juliana Machado Schardosim ◽  
Maria Luzia Chollopetz da Cunha
Keyword(s):  
Birth Weight ◽  
Preterm Infants ◽  
Neonatal Sepsis ◽  
Late Onset ◽  
Newborn Infants ◽  
University Hospital ◽  
Hospital Data ◽  
Coagulase Negative Staphylococci ◽  
The University ◽  
Preterm Newborns

Objective: the research objective was to characterize preterm infants with birth weight under 1500 g, and to identify the incidence of late-onset neonatal sepsis among this population. Methods: a prospective cohort study with a sample of 30 preterm newborns that weighed under 1500 g and were hospitalized in the NICU of the university hospital. Data were collected from January to December 2013 using a structured instrument. Results: of the 30 neonates included in the study, 14 developed late-onset neonatal sepsis with a prevalence of coagulase-negative staphylococci. Conclusions: the incidence of late-onset neonatal sepsis indicates a vulnerability in preterm infants due to immunological immaturity. These results reveal that knowledge of the profile of newborn infants admitted to the NICU and the risk factors to which they are exposed are central to the planning of nursing care for these patients. Future studies should address strategies for preventing nosocomial infection.

scholarly journals Association of late-onset neonatal sepsis with late neurodevelopment in the first two years of life of preterm infants with very low birth weight

2014 ◽  
Vol 90 (1) ◽  
pp. 50-57 ◽  
Author(s):  
Cláudia Regina Hentges ◽  
Rita C. Silveira ◽  
Renato Soibelmann Procianoy ◽  
Clarissa Gutierrez Carvalho ◽  
Gabriela Ribeiro Filipouski ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Preterm Infants ◽  
Neonatal Sepsis ◽  
Very Low Birth Weight ◽  
Late Onset

scholarly journals Association of late‐onset neonatal sepsis with late neurodevelopment in the first two years of life of preterm infants with very low birth weight

2014 ◽  
Vol 90 (1) ◽  
pp. 50-57
Author(s):  
Cláudia R. Hentges ◽  
Rita C. Silveira ◽  
Renato S. Procianoy ◽  
Clarissa G. Carvalho ◽  
Gabriela R. Filipouski ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Preterm Infants ◽  
Neonatal Sepsis ◽  
Very Low Birth Weight ◽  
Late Onset

scholarly journals Reduction of exposure to blood donors in preterm infants submitted to red blood cell transfusions using pediatric satellite packs

2013 ◽  
Vol 31 (3) ◽  
pp. 285-292 ◽  
Author(s):  
Cristina Lika Uezima ◽  
Ariane Moreira Barreto ◽  
Ruth Guinsburg ◽  
Akemi Kuroda Chiba ◽  
José Orlando Bordin ◽  
...  
Keyword(s):  
Birth Weight ◽  
Preterm Infants ◽  
Blood Donor ◽  
Blood Donors ◽  
Newborn Infants ◽  
Median Number ◽  
Erythrocyte Transfusion ◽  
Factors Associated ◽  
Group 2 ◽  
Group 1

OBJECTIVE: In preterm newborn infants transfused with erythrocytes stored up to 28 days, to compare the reduction of blood donor exposure in two groups of infants classified according to birth weight. METHODS: A prospective study was conducted with preterm infants with birth weight <1000g (Group 1) and 1000-1499g (Group 2), born between April, 2008 and December, 2009. Neonates submitted to exchange transfusions, emergency erythrocyte transfusion, or those who died in the first 24 hours of life were excluded. Transfusions were indicated according to the local guideline using pediatric transfusion satellite bags. Demographic and clinical data, besides number of transfusions and donors were assessed. . Logistic regression analysis was performed to determine factors associated with multiple transfusions. RESULTS: 30 and 48 neonates were included in Groups 1 and 2, respectively. The percentage of newborns with more than one erythrocyte transfusion (90 versus 11%), the median number of transfusions (3 versus 1) and the median of blood donors (2 versus 1) were higher in Group 1 (p<0.001), compared to Group 2. Among those with multiple transfusions, 14 (82%) and one (50%) presented 50% reduction in the number of blood donors, respectively in Groups 1 and 2. Factors associated with multiple transfusions were: birth weight <1000g (OR 11.91; 95%CI 2.14-66.27) and presence of arterial umbilical catheter (OR 8.59; 95%CI 1.94-38.13), adjusted for confounders. CONCLUSIONS: The efficacy of pediatrics satellites bags on blood donor reduction was higher in preterm infants with birth weight <1000g.

scholarly journals cfDNA and DNases: New Biomarkers of Sepsis in Preterm Neonates—A Pilot Study

Cells ◽  
2022 ◽  
Vol 11 (2) ◽  
pp. 192
Author(s):  
Moritz Lenz ◽  
Thomas Maiberger ◽  
Lina Armbrust ◽  
Antonia Kiwit ◽  
Axel Von der Wense ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Neonatal Sepsis ◽  
Early Onset ◽  
Late Onset ◽  
Dnase I ◽  
Sepsis Group ◽  
Preterm Neonates ◽  
Control Group ◽  
Suspected Sepsis ◽  
Epidemiological Characteristics

Introduction: An early and accurate diagnosis of early onset neonatal sepsis (EONS) and late onset neonatal sepsis (LONS) is essential to improve the outcome of this devastating conditions. Especially, preterm infants are at risk. Reliable biomarkers are rare, clinical decision-making depends on clinical appearance and multiple laboratory findings. Markers of NET formation and NET turnover might improve diagnostic precision. Aim of this study was to evaluate the diagnostic value of NETs in sepsis diagnosis in neonatal preterm infants. Methods: Plasma samples of neonatal preterm infants with suspected sepsis were collected. Blood samples were assayed for markers of NET formation and NET turnover: cfDNA, DNase1, nucleosome, NE, and H3Cit. All clinical findings, values of laboratory markers, and epidemiological characteristics were collected retrospectively. Two subpopulations were created to divide EONS from LONS. EMA sepsis criteria for neonatal sepsis were used to generate a sepsis group (EMA positive) and a control group (EMA negative). Results: A total of 31 preterm neonates with suspected sepsis were included. Out of these, nine patients met the criteria for sepsis according to EMA. Regarding early onset neonatal sepsis (3 EONS vs. 10 controls), cfDNA, DNase I, nucleosome, and CRP were elevated significantly. H3Cit and NE did not show any significant elevations. In the late onset sepsis collective (6 LONS vs. 12 controls), cfDNA, DNase I, and CRP differed significantly compared to control group.

scholarly journals Aleitamento materno exclusivo em prematuros de hospitais Amigo da Criança: estudo comparativo

2018 ◽  
Vol 16 (3) ◽  
pp. 319
Author(s):  
Ariane Thaise Alves Monteiro ◽  
Edilaine Giovanini Rossetto ◽  
Kauana Olanda Pereira ◽  
Mariana Charif Lakoski ◽  
Marcela Maria Birolim ◽  
...  
Keyword(s):  
Comparative Study ◽  
Hospital Discharge ◽  
Preterm Infants ◽  
Premature Infants ◽  
Exclusive Breastfeeding ◽  
Clinical Characteristics ◽  
Demographic Characteristics ◽  
University Hospital ◽  
Factors Associated ◽  
The University

Aim: to compare the prevalence of exclusive breastfeeding (EBF) and to verify the factors associated with its interruption in premature infants hospitalized at Baby-Friendly hospitals. Method: this is a comparative study performed with 107 premature infants admitted to the neonatal unit of two hospitals in Paraná. Data were obtained through interviews with mothers and analysis of infant records at hospital discharge and 15 days after delivery. Results: the prevalence of EBF was 29.2% in the University Hospital and 15.3% in the Philanthropic Hospital. At hospital discharge, associations with clinical characteristics of infants predominated, and 15 days after discharge there was a greater association with the socio-demographic characteristics of the parents. Conclusion: the prevalence of EBF, which was shown to be low at the time of hospital discharge in both hospitals, decreased after discharge, reinforcing the need for other strategies, in addition to those provided at Baby-Friendly hospitals, for the promotion and support of EBF in preterm infants.

Very Low Birth Weight Preterm Infants With Early Onset Neonatal Sepsis

2005 ◽  
Vol 24 (7) ◽  
pp. 635-639 ◽  
Author(s):  
Barbara J. Stoll ◽  
Nellie I. Hansen ◽  
Rosemary D. Higgins ◽  
Avroy A. Fanaroff ◽  
Shahnaz Duara ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Preterm Infants ◽  
Neonatal Sepsis ◽  
Early Onset ◽  
Very Low Birth Weight

64 PROCALCITONIN AS A SCREENING TEST IN LATE ONSET SEPSIS IN VERY LOW BIRTH WEIGHT PRETERM INFANTS.

2004 ◽  
Vol 52 (Suppl 2) ◽  
pp. S356.5-S356
Author(s):  
R. Vazzalwar ◽  
E. Pina-Rodriques ◽  
B. Puppala ◽  
P. Krieger ◽  
D. Angst ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Preterm Infants ◽  
Screening Test ◽  
Very Low Birth Weight ◽  
Late Onset ◽  
Late Onset Sepsis

scholarly journals Pathological staging of chorioamnionitis contributes to complications in preterm infants

2020 ◽  
Vol 46 (1) ◽  
Author(s):  
Jiayu Miao ◽  
Zhuxiao Ren ◽  
Yunbei Rao ◽  
Xin Xia ◽  
Jianlan Wang ◽  
...  
Keyword(s):  
Birth Weight ◽  
Preterm Infants ◽  
Gestational Age ◽  
Intraventricular Hemorrhage ◽  
Independent Risk Factor ◽  
Late Onset ◽  
Obstetrics And Gynecology ◽  
Single Center ◽  
Pathological Staging ◽  
The Difference

Abstract Objective To investigate the effect of pathological staging of chorioamnionitis (CA) on complications in preterm infants; Methods A single-center, retrospective study was conducted to choose singleton preterm infants (gestational age < 37 weeks) from the Department of Obstetrics and Gynecology in our hospital from December 2016 to December 2017. The basic data and placental pathological results were retrospectively collected. According to the placental pathological results of whether inflammation infiltrating amnion, CA 0/I phase was classified into non-amnionitis group, CA II/III phase was classified into amnionitis group, the incidence of common complications in preterm infants was compared. Further, logistic regression was used to analyze the effects of amnionitis on complications after being adjusted to gestational age, birth weight and thrombocytopenia. Results A total of 221 preterm infants were enrolled, including 186 cases in non-amnionitis group and 35 cases in amnionitis group. The gestational age of amnionitis group (32.00 ± 2.71 weeks) was significantly lower than non-amnionitis group (34.14 ± 2.06 weeks), birth weight (1.93 ± 0.64 kg) was significantly lower than that of non-amnionitis group (2.26 ± 0.58 kg), and the hospital stay in amnionitis group was significantly longer (25.71 ± 19.23 days), all of the difference above was statistically significant(P < 0.05). The incidence of intraventricular hemorrhage (IVH) in amnionitis group (37.14%) was significantly higher than that in non-amnionitis group (13.98%) (P = 0.002), and the risk of IVH was significantly increased by amnionitis (OR = 3.636, 95%CI: 1.632–8.102); after correction of gestational age, birth weight and thrombocytopenia, the risk of IVH was still significantly increased (OR = 2.471, P = 0.046, 95% CI: 1.015–6.015). And the late-onset IVH was more common (P = 0.009). Conclusion Amnionitis leads to a significant reduction in gestational age and birth weight in preterm infants, and it is an independent risk factor for IVH.

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