scholarly journals Immunological disturbance in West and Lennox-Gastaut syndromes

1984 ◽  
Vol 42 (2) ◽  
pp. 132-139 ◽  
Author(s):  
Terezinha C. B. Montelli ◽  
Norma G. S. Mota ◽  
M. Terezinha S. Peraçoli ◽  
Elza A. Torres ◽  
M. Thereza Rezkallah-Iwasso

Cell-mediated and humoral immunity were investigated in 18 patients with West syndrome, 12 with Lennox-Gastaut syndrome and 19 healthy controls. The study included determination of Ô and  peripheral blood lymphocytes, serum levels of IgG, IgA and IgM, skin sensibilization with DNCB, intracutaneous PHA, leucocyte migration inhibition test and lymphocyte blastic transformation in the presence of PHA. Cell-mediated deficiency was detected in 28 children whereas low levels of immunoglobulins were observed only in 6 children. Immunological disturbances were more prominent in children with West syndrome.

1978 ◽  
Vol 54 (8) ◽  
pp. 909-920
Author(s):  
Susumu SAKAGUCHI ◽  
Michio NAKAZAWA ◽  
Syuji NAKAMURA ◽  
Yasuko KONO ◽  
Hideo HAZEKI ◽  
...  

1981 ◽  
Vol 67 (3) ◽  
pp. 163-167 ◽  
Author(s):  
Maria Caterina Sirianni ◽  
Giuseppe Luzi ◽  
Claudio Iavarone ◽  
Marisa Papaluca ◽  
Massimo Fiorilli ◽  
...  

The direct leucocyte migration inhibition test in capillary tubes was used to test 10 patients with colonic adenocarcinoma against KCl soluble extracts of an allogenic colon cancer and an allogenic normal colon fragment. Inhibition was consistently found with the cancer extract but not with the normal tissue extract. None of the control group of patients affected by other tumors, intestinal and liver disorders showed a migration inhibition in response to the colonic tumor extract. Our findings strongly suggest the presence of a tumor-associated antigen in the cancer extract.


Gut ◽  
1983 ◽  
Vol 24 (4) ◽  
pp. 311-317 ◽  
Author(s):  
F G Simpson ◽  
H P Field ◽  
P D Howdle ◽  
D A Robertson ◽  
M S Losowsky

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