scholarly journals Guidelines for drug treatment of epilepsy: a critical review

2008 ◽  
Vol 66 (3a) ◽  
pp. 591-599 ◽  
Author(s):  
Carlos A.M. Guerreiro

This article critically reviews the role of evidence-based medicine and its guidelines, from their logistic preparation to their interpretation. The strengths and weaknesses of the methodological points are presented, as well the reasons for the extreme popularity of the guidelines in developed countries. The review discusses the main foundations of the most cited guidelines and some recent large studies. Some of the final conclusions are that clinical experience is always an important factor to consider, even in the face of solid evidence, to achieve the best possible management of any particular patient.

2020 ◽  
Vol 17 (5) ◽  
pp. 445-449
Author(s):  
Artem A. Ivanov

Acute gastroenteritis is an infectious disease, often with viral etiology, which can include diarrhea (three or more loose or liquid stools in 24 hours) and the possible presence of vomiting and fever. This pathology is common disease for any pediatrician in his practice. Currently, many specialists use a variety of different guidelines and approaches to the treatment of acute gastroenteritis, thus not all of them meet the criteria of evidence-based medicine. This review presents contemporary approaches to the pharmacotherapy of acute gastroenteritis based on world experience and guidelines from developed countries. This review also covers the issues of specific prevention of rotavirus infection and the role of vaccination in prevention of certain somatic diseases.


2011 ◽  
Vol 33 (1) ◽  
pp. 3-9 ◽  
Author(s):  
Bob Wilffert ◽  
◽  
Jesse Swen ◽  
Hans Mulder ◽  
Daan Touw ◽  
...  

2017 ◽  
Vol 4 (2) ◽  
pp. 47-48 ◽  
Author(s):  
Joshua Z. Goldenberg ◽  
Erica B. Oberg ◽  
Jane Guiltinan ◽  
Rachelle L. McCarty

Author(s):  
Natalia A. Vyatkina

The term "evidence-based medicine" is being increasingly used by various sources of information today, and becomes a discussion subject of professional communities and ordinary citizens. Apart from a brief insight into the origin and development of evidence-based medicine in the world and in Russia, the article deals with the anthropological analysis of the attitudes of the modern Russian physicians and patients towards both the understanding of the term and the current status, prospects and possible risks of the development of this discipline in our country. The views of respondents about the role of pharmaceutical companies, the state and the balance between the development and implementation of clinical guidelines and individual cases are considered. The article presents the arguments of patients about whether there is still a "physician blessed by God" and whether it is important for them that the person who they address for help works in the paradigm of evidence-based medicine. Physicians question whether healing itself is still an art, or evidence-based medicine has finally turned it into a business and well-organized mechanism, which could protect them from criminal prosecution in a critical situation.


2019 ◽  
Vol 98 (1) ◽  
pp. 82-86 ◽  
Author(s):  
Aleksandr O. Karelin ◽  
A. Yu. Lomtev ◽  
M. V. Volkodaeva ◽  
G. B. Yeremin

The air pollution has got a great risk to the health of the population. In the risk assessment, objective and subjective uncertainties have appeared. The aim of the study to analyze the uncertainties arising in the assessment of health adverse effects of air pollution and possible ways to decrease them. Methods of the scientific hypothetical deductive cognition, general logical methods, and approaches of researches: analysis, synthesis, abstracting, generalization, induction. In this paper, we analyzed the uncertainties arising in the risk assessment for the health of population caused by air pollution and proposed measures to improve the approaches to assessment and management of the risk. The analysis revealed the main causes of the uncertainties. In the field of the atmospheric air monitoring, they are lack of modern equipment and officially approved methods for measurement, the absence of criteria and recommendation for choosing of controlled air pollutants. For the health assessment, it is advisable to use epidemiological methods and methodology of risk analysis taking into account the uncertainties of each approach. Usage of the geographic information systems let increase the informativity of data and efficiency of analysis. Accurate quantification of the risk for the health of population caused by air pollution is a difficult to challenge. It is necessary to take into account the experience of developed countries in the development of domestic criteria for the selection of substances for the control of atmospheric air quality. It is advisable to combine the analysis of data on the actual concentrations of pollutants obtained at stationary and mobile observation posts, and integrated calculations of air pollution. It is necessary to use basic concepts of evidence-based medicine to identify the real impact of air pollutants on public health and reduce uncertainties. Conclusion. In the assessment of risk for health caused by air pollution a lot of objective and subjective uncertainties appear. Based on the principles of evidence-based medicine, they should be comprehensively analyzed and minimized using modern methodological approaches, taking into account their capabilities and limitations.


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