scholarly journals Molecular epidemiology of dengue viruses in Brazil

2000 ◽  
Vol 16 (1) ◽  
pp. 205-211 ◽  
Author(s):  
Rita Maria Ribeiro Nogueira ◽  
Marize Pereira Miagostovich ◽  
Hermann Gonçalves Schatzmayr

Dengue viruses (DEN) are found as four antigenically distinct serotypes designated DEN-1, 2, 3, and 4. Laboratory evidence that strain-intratypical variation occurs among DEN viruses has been demonstrated since the 1970s, although only with the advances in molecular technologies has it been possible to determine the genetic variability of each serotype. Genotypical identification has proven to be a useful tool for determining the origin and spread of epidemics and to correlate virulence of strains. In this report we present the results of molecular epidemiological studies with the DEN-1 and DEN-2 viruses that caused dengue epidemics in Brazil during the last decade.

Author(s):  
Dennis W. Trent ◽  
Charles L. Manske ◽  
George E. Fox ◽  
May C. Chu ◽  
Srisakul C. Kliks ◽  
...  

2005 ◽  
Vol 38 (6) ◽  
pp. 843-852 ◽  
Author(s):  
R.J. Pires Neto ◽  
D.M. Lima ◽  
S.O. de Paula ◽  
C.M. Lima ◽  
I.M. Rocco ◽  
...  

2020 ◽  
Vol 19 (2) ◽  
pp. 447-453
Author(s):  
Abdulaziz Alqasim

Extra-intestinal pathogenic Escherichia coli (ExPEC) is commonly associated with causing urinary tract and bloodstream infections. Over the past two decades, the antimicrobial resistance of ExPEC has increasingly been reported [1]. Given that Saudi Arabia annually hosts mass religious events, such as Hajj, this review investigated several aspects of antimicrobial resistance of ExPEC in this country including the current prevalence of resistance and molecular epidemiology of ExPEC isolates. Generally, the overall prevalence of antibiotic resistance of ExPEC in Saudi Arabia is on increase. The current emergence of colistin resistance in ExPEC represents a major challenge to public health. Local molecular epidemiological studies have shown the dominance of E. coli sequence type 131 (E. coli ST131) over other major ExPEC STs. This is an important observation given that this clone has been associated with high multidrug resistance and extended-spectrum β-lactamases carriage. To reduce the burden of this resistance in the future, it would be crucial to avoid uncontrolled use of antibiotics in either clinical settings or animal food industry. Keywords: Extra-intestinal pathogenic Escherichia coli, Antimicrobial resistance, ST131, Saudi Arabia, Colistin resistance, Extended-spectrum β-lactamases


2003 ◽  
Vol 84 (12) ◽  
pp. 3191-3201 ◽  
Author(s):  
Mauro Costa-Mattioli ◽  
Anna Di Napoli ◽  
Virginie Ferré ◽  
Sylviane Billaudel ◽  
Raul Perez-Bercoff ◽  
...  

Knowledge of the molecular biology of hepatitis A virus (HAV) has increased exponentially since its identification. HAV exploits all known mechanisms of genetic variation to ensure survival, including mutation and genetic recombination. HAV has been characterized by the emergence of different genotypes, three human antigenic variants and only one major serotype. This paper reviews the genetic variability and molecular epidemiology of HAV. Its evolutionary mechanisms are described with particular emphasis on genetic recombination and HAV mutation rate. Genotypic classification methods are also discussed.


2020 ◽  
Vol 73 (4) ◽  
pp. 300-303
Author(s):  
Chuan Guo ◽  
Jiemin Lin ◽  
Wan Chen ◽  
Zhihua Zhang ◽  
De Wu ◽  
...  

2005 ◽  
Vol 71 (4) ◽  
pp. 1953-1958 ◽  
Author(s):  
B. L. Siemer ◽  
E. M. Nielsen ◽  
S. L. W. On

ABSTRACT Campylobacter coli is an infrequently studied but important food-borne pathogen with a wide natural distribution. We investigated its molecular epidemiology by use of amplified fragment length polymorphism (AFLP)-based genotyping and Penner serotyping. Serotype reference strains and 177 Danish isolates of diverse origin identified by routine phenotyping as C. coli were examined. Molecular tools identified some 12% of field isolates as Campylobacter jejuni, emphasizing the need for improved identification methods in routine laboratories. Cluster analysis of AFLP profiles of 174 confirmed C. coli isolates revealed a difference in the distribution of isolates from pig and poultry (chicken, duck, turkey, and ostrich) species and indicated the various poultry species, but not pigs, to be likely sources of human C. coli infection. A poor correlation was observed between serotyping and AFLP profiling, suggesting that the former method has limited value in epidemiological studies of this species.


2015 ◽  
Vol 43 (1) ◽  
pp. 21-27 ◽  
Author(s):  
Kyaw Zin Thant ◽  
Mya Myat Ngwe Tun ◽  
Maria del Carmen Parquet ◽  
Shingo Inoue ◽  
Yee Yee Lwin ◽  
...  

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