Antiacetylcholinesterase and antioxidant activity of essential oils from six medicinal plants from Burkina Faso

The study of bioactive molecules of natural origin is a focus of current research. Thymus algeriensis and Artemisia herba-alba are two medicinal plants widely used by the Moroccan population in the traditional treatment of several pathologies linked to inflammation. This study aimed to evaluate the single and combined antioxidant, anti-inflammatory and analgesic effects of the essential oils extracted from these two medicinal plants, and also their potential toxicity. Essential oils were extracted using hydro-distillation in a Clevenger-type apparatus. The antioxidant activity was evaluated by two methods: the scavenging of the free radical DPPH, and the reduction in iron. Anti-inflammatory activity was evaluated by evaluating the edema development induced by carrageenan injecting, while the analgesic power was evaluated according to the number of abdominal contortions induced by the intraperitoneal injection of acetic acid (0.7%). The acute oral toxicity was performed to assess the potential toxicity of the studied EOs, followed by an analysis of the blood biochemical parameters. The results of the two antioxidant tests indicated that our extract mixture exhibits good iron reduction capacity and very interesting DPPH free radical scavenging power, with an IC50 of around 4.38 ± 0.98 μg/mL higher than that of the benchmark antioxidant, BHT. The anti-inflammatory test demonstrated that the mixture administered orally at a dose of 150 mg/kg has a better activity, exceeding that of 1% Diclofenac, with a percentage of maximum inhibition of the edema of 89.99 ± 4.08. The number of cramps in the mice treated with the mixture at a dose of 150 mg/kg is significantly lower (29.80 ± 1.92) than those of the group treated with Tramadol (42.00 ± 2.70), respectively. The toxicity results show no signs of toxicity with an LD50 greater than 150 mg/Kg. These interesting results show that the two plants’ EOs had an important anti-inflammatory, analgesic, and antioxidant activity, and also a powerful synergistic effect, which encourages further in-depth investigations on their pharmacological proprieties.

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Ethnobotanical study, phytochemistry and antioxidant activity of medicinal plants used in the treatment of inflammation in two cities of Burkina Faso

10.30574/msarr.2021.2.2.0034 ◽

2021 ◽

Vol 2 (2) ◽

pp. 01-012

Author(s):

Armandine LEMA ◽

Mindiédiba Jean BANGOU ◽

Tangbadioa Hervé COULIDIATI ◽

Mamadou SAWADOGO ◽

Hyacinthe M THIOMBIANO ◽

...

Keyword(s):

Antioxidant Activity ◽

Medicinal Plants ◽

Burkina Faso ◽

Urban Areas ◽

Polyphenolic Compounds ◽

Total Phenolic ◽

Ethnobotanical Study ◽

Ethnobotanical Survey ◽

Phytochemical Study ◽

Traditional Practitioners

Background and Objective: The present study aimed to contribute to the knowledge of medicinal plants used in the treatment of inflammation in Burkina Faso, as well as to quanti fy the polyphenolic compounds content and to evaluate the antioxidant activity of two most solicited species. Materials and Methods: An ethnobotanical survey was carried out in the urban areas of Bobo-Dioulasso and Fada N'Gourma in order to collect sociodemographic and ethnobotanical data from traditional practitioners. Methanolic extracts of the plant organs were obtained using an extractor apparatus. The quantification of polyphenolic compounds contents was done by spectrophotometry, respectively with the Folin Ciocalteu reagent and aluminum trichloride. Likewise, antioxidant activity was evaluated by three methods (ABTS●+ DPPH● and FRAP) and the reading of optical densities was performed with the spectrophotometer. Results: One hundred and twelve (112) traditional practitioners were interviewed and seventy-three (73) plant species were identified in both areas. According to the frequency of quotation, Entada africana and Khaya senegalensis species were retained for further study. Phytochemical study revealed that the total phenolic content was high in the trunk bark of K. senegalensis (73.12 ± 1.8 mg GAE/100mg) and the total flavonoid content in the trunk bark of E. africana (8.42 ± 0.78 mg QE/100mg). Of the antioxidant activity, the highest value was observed at the level of the ABTS●+ radical inhibition method with the best result 13247.2 ± 219.84 µmol AAE/g (leaves of E. africana). Conclusion: The phytochemical analyses of these species indicate their richness in total phenolics and flavonoids contents, and could justify their use in the treatment of inflammatory diseases.

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Chemical composition and antioxidant activity of essential oils extracted from Egyptian medicinal plants and effect on oxidative stability of soybean oil in storage

Medicinal Plants - International Journal of Phytomedicines and Related Industries ◽

10.5958/j.0975-4261.2.2.013 ◽

2010 ◽

Vol 2 (2) ◽

pp. 79 ◽

Cited By ~ 1

Author(s):

Ahmed E.M. Abdalla

Keyword(s):

Antioxidant Activity ◽

Chemical Composition ◽

Medicinal Plants ◽

Soybean Oil ◽

Essential Oils ◽

Oxidative Stability

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Oxygen introduction during extraction and the improvement of antioxidant activity of essential oils of basil, lemon and lemongrass

Ciência Rural ◽

10.1590/0103-8478cr20170045 ◽

2017 ◽

Vol 47 (8) ◽

Cited By ~ 2

Author(s):

Daniele de Freitas Ferreira ◽

Flávia Michelon Dalla Nora ◽

Bruna Nichelle Lucas ◽

Cristiano Ragagnin de Menezes ◽

Alexandre José Cichoski ◽

...

Keyword(s):

Antioxidant Activity ◽

Quality Control ◽

Medicinal Plants ◽

Essential Oil ◽

Essential Oils ◽

Oil Extraction ◽

Suitable Alternative ◽

Simple Modification ◽

Oxygenated Compounds ◽

Food Quality Control

ABSTRACT: Essential oil extraction is commonly carried out by using the hydrodistillation method, which is described in official compendia of food quality control and medicinal plants. Despite the widespread use of this method, few studies have evaluated the effect of the atmosphere change during extraction on the composition and antioxidant activity of essentials oils. Therefore, a study of oxygen introduction influence during the extraction of essential oils from basil, lemongrass and lemon by hydrodistillation was performed. Total amount of oxygenated compounds (e.g., linalool, camphor, α-terpineol, neral, geranial, eugenol and α-muurolol) increased for all essential oils extracted under oxygen flow. Antioxidant activity evaluated by using the ORAC method significantly increased (P<0.0001) with oxygen from 618 to 906, 355 to 613 and 72 to 262µmol Trolox g-1 oil for basil, lemongrass and lemon, respectively. Therefore, the simple modification proposed could be considered a suitable alternative to obtain essential oils with higher antioxidant activity.

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Polyphenols quantification and antioxidant activity of methanolic and aqueous extracts from eight medicinal plants used to manage avian diseases in Burkina Faso

Journal of Medicinal Plants Research ◽

10.5897/jmpr2021.7105 ◽

2021 ◽

Vol 15 (5) ◽

pp. 226-231

Author(s):

Kagambega Windmi ◽

Nag-Tiero Meda Roland ◽

Kouliga Koama Benjamin ◽

Drabo Anne-Flora ◽

Belem Hadidjatou ◽

...

Keyword(s):

Antioxidant Activity ◽

Medicinal Plants ◽

Burkina Faso ◽

Aqueous Extracts ◽

Avian Diseases

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Chemical composition and antioxidant activity of essential oils of three endemic medicinal plants of Iran

Bangladesh Journal of Botany ◽

10.3329/bjb.v42i2.18038 ◽

2014 ◽

Vol 42 (2) ◽

pp. 327-332 ◽

Cited By ~ 8

Author(s):

Abdollah Ghasemi Pirbalouti ◽

Leila Sedaghat ◽

Behzad Hamedi ◽

Farhang Tirgir

Keyword(s):

Antioxidant Activity ◽

Chemical Composition ◽

Medicinal Plants ◽

Essential Oils ◽

Food Industry ◽

Aerial Parts ◽

High Antioxidant Activity

Hydro-distillated essential oils (EO) antioxidant activity of three endemic medicinal plants of Iran namely, Heracleum lasiopetalum Boiss., Kelussia odoratissima Mozaff., and Ferulago angulata (Schlecht.) Boiss were studied. The results indicated that the major components of the EOs were 2-ethylhexyl acetate (34.5%), n-octanol (6.5%), and hexanol (5.1%) for H. lasiopetalum fruits; Z-?-ocimene (20.5), ?-pinene (11.6%), and ?-phellandrene (9.3) for F. angulata aerial parts; ?-pinene (20.1%), 1,8-cineole (18.2%), and Zligustilide (15.5%) for K. odoratissima aerial parts. The three EOs having high antioxidant activity could be used as an alternative preservative instead of synthetic ones in food industry. DOI: http://dx.doi.org/10.3329/bjb.v42i2.18038 Bangladesh J. Bot. 42(2): 327-332, 2013 (December)

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Antioxidant activity some endemic Iranian medicinal plants (Apiaceae)

Planta Medica ◽

10.1055/s-0032-1320920 ◽

2012 ◽

Vol 78 (11) ◽

Author(s):

M Setayesh ◽

A Siahpoosh ◽

A Ghasemi Pirbalouti ◽

R Abdizadeh

Keyword(s):

Antioxidant Activity ◽

Medicinal Plants

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The essential oils of some medicinal plants on the immune system of rainbow trout (Oncorhynchus mykiss)

Planta Medica ◽

10.1055/s-0032-1320793 ◽

2012 ◽

Vol 78 (11) ◽

Author(s):

A Ghasemi Pirbalouti ◽

E Pirali ◽

G Pishkar ◽

S Mohammadali Jalali ◽

M Reyesi ◽

...

Keyword(s):

Immune System ◽

Rainbow Trout ◽

Medicinal Plants ◽

Oncorhynchus Mykiss ◽

Essential Oils ◽

Rainbow Trout Oncorhynchus Mykiss

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SKRINING FITOKIMIA DAN UJI AKTIVITAS ANTIOKSIDAN DAN ANTITUMOR 20 TUMBUHAN OBAT ASAL KABUPATEN MANOKWARI

Jurnal Natural ◽

10.30862/jn.v7i1.678 ◽

2008 ◽

Vol 7 (1) ◽

Author(s):

Bimo Budi Santoso

Keyword(s):

Antioxidant Activity ◽

Medicinal Plants ◽

Antitumor Activity ◽

Traditional Method ◽

Extraction Efficiency ◽

Phenolic Content ◽

Antioxidant Activities ◽

Total Phenolic ◽

Phenolic Contents ◽

Total Phenolic Contents

Flavanoid, steroid, and terpenoid contents of 20 Manokwari medicinal plants were analyzed. The antioxidant activity, total phenolic contents and antitumor activity of 20 Manokwari medicinal plants were also evaluated. The result shows that 83% positif to flavanoid test, 59% positif to terpenoid test and only 25% positif steroid. Antioxidant activity and total phenolic contents evaluated using Ferric Thiocianate (FTC) and Folin-Ciocalteu methods respectively. Antioxidant activity and total phenolic contents of medicinal plants were extracted by the traditional method, boiling in water and also in 80% methanol. Twenty plants evaluated in both exstracts have significantly varies of antioxidant activities and phenolic contents, A significant and linier correlation coefficient between the antioxidant activity and the total phenolic content was found in both aqueous (R2= 0,77) and methanol (R2 = 0,85). Antitumor activity was tested using cell maurine P-388 and only 2 of medicinal plants are active to inhibit cell maurine P-388. Comparing extraction efficiency of the two methods, the methanol extracted phenolic compounds more efficiently, and antioxidant activity of the extract was higher.

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