Determination of Apoptotic Effect of Juglone on Human Bladder Cancer TCC-SUP and RT-4 Cells: An In Vitro Study

Author(s):  
Dilek Bayram ◽  
İlkay Armagan ◽  
Meltem Özgöcmen ◽  
Nurgül Senol ◽  
Mustafa Calapoglu
2008 ◽  
Vol 16 (4) ◽  
pp. 275-279 ◽  
Author(s):  
Evandro Watanabe ◽  
Juliane Maria Guerreiro Tanomaru ◽  
Andresa Piacezzi Nascimento ◽  
Fumio Matoba-Júnior ◽  
Mario Tanomaru-Filho ◽  
...  

Author(s):  
Feifan Wang ◽  
Yan Zhang ◽  
Xuejian Zhou ◽  
Xianwu Chen ◽  
Jiayong Xiang ◽  
...  

Circular RNA (circRNA) is a newly discovered endogenous non-coding RNA (ncRNA), which is characterized with a closed circular structure. A growing body of evidence has verified the vital roles of circRNAs in human cancer. In this research, we selected circPPP1CB as a study object by circRNA sequencing and quantitative real-time PCR (qRT-PCR) validation in human bladder cancer (BC). CircPPP1CB is downregulated in BC and is negatively correlated with clinical stages and histological grades. Functionally, circPPP1CB modulated cell growth, metastasis, and epithelial-to-mesenchymal transition (EMT) process in vitro and in vivo. Mechanically, we performed various experiments to verify the circPPP1CB/miR-1307-3p/SMG1 regulatory axis. Taken together, our results demonstrated that circPPP1CB participates in tumor growth, metastasis, and EMT process by interacting with the miR-1307-3p/SMG1 axis, and that circPPP1CB might be a novel therapeutic target and diagnostic biomarker in human BC.


2000 ◽  
Vol 72 (2) ◽  
pp. 226 ◽  
Author(s):  
René C. Krieg ◽  
Sonja Fickweiler ◽  
Otto S. Wolfbeis ◽  
Ruth Knuechel

NIR news ◽  
2012 ◽  
Vol 23 (6) ◽  
pp. 13-14 ◽  
Author(s):  
Akifumi Ikehata ◽  
Kunio Sashida ◽  
Shanji Park ◽  
Tsutomu Okura ◽  
Yutaka Terada

2018 ◽  
Vol Volume 13 ◽  
pp. 5733-5741 ◽  
Author(s):  
Elham Shahhoseini ◽  
Prabhakar Ramachandran ◽  
William Patterson ◽  
Moshi Geso

Sign in / Sign up

Export Citation Format

Share Document