EFFECTS OF ADMINISTERING ANTISERA TO MOUSE GROWTH HORMONE AND PROLACTIN ON GAIN IN LITTER WEIGHT AND ON MAMMARY NUCLEIC ACID CONTENT OF LACTATING C3H MICE

1972 ◽  
Vol 55 (1) ◽  
pp. 31-NP ◽  
Author(s):  
Y. N. SINHA ◽  
U. J. LEWIS ◽  
W. P. VANDERLAAN
Keyword(s):  
Growth Hormone ◽  
Body Weight ◽  
Nucleic Acid ◽  
Acid Content ◽  
Nucleic Acid Content ◽  
Ovarian Weight ◽  
Litter Weight ◽  
Dna And Rna ◽  
Lactating Mothers ◽  
C3h Mice

SUMMARY The effects of administering antiserum to mouse growth hormone (GH) and prolactin on lactation and mammary nucleic acid content of C3H mice were studied. Injections of either antisera to lactating mothers suppressed the gain in body weight of their suckling young, GH antiserum more readily than prolactin antiserum. A combined injection of the two antisera resulted in an immediate retardation of the gain in body weight of the young. Although both antisera reduced DNA and RNA content of the mammary gland, GH antiserum appeared to affect DNA content predominantly whereas prolactin antiserum affected RNA: DNA ratio, suggesting involvement of GH primarily in cell proliferation and of prolactin in protein synthesis. Both antisera abolished the gain in maternal body weight. Mouse GH antiserum decreased maternal adrenal weight whereas both antisera reduced ovarian weight. The results suggest that both GH and prolactin may be involved in normal lactation and in maintenance of body weight in C3H mice.

THE EFFECT OF GROWTH HORMONE ON THE NUCLEIC ACID CONTENT OF THE DEVELOPING CHICK EMBRYO1

Endocrinology ◽  
1953 ◽  
Vol 53 (5) ◽  
pp. 520-526 ◽  
Author(s):  
TUNG-YUE WANG ◽  
KUANG-MEI HSIEH ◽  
HERMAN T. BLUMENTHAL
Keyword(s):  
Growth Hormone ◽  
Nucleic Acid ◽  
Acid Content ◽  
Nucleic Acid Content

Influence of the RNA content on oogenesis in the bobbed mutants of Drosophila melanogaster

Development ◽  
1971 ◽  
Vol 25 (2) ◽  
pp. 237-246
Author(s):  
Jag Mohan
Keyword(s):  
Drosophila Melanogaster ◽  
Nucleic Acid ◽  
Acid Content ◽  
Nucleic Acid Content ◽  
Wild Type ◽  
Dna And Rna ◽  
Stage Of Development ◽  
Rna Content ◽  
Egg Chambers ◽  
Total Dna

Developing egg chambers of Drosophila melanogaster (wild-type and bobbed mutants) have been examined for their nucleic acid content by cytophotometric methods. No differences were observed in the total DNA and RNA content of the egg chambers at all stages between the bobbed mutants and the wild type. It is shown that the process of oogenesis in bobbed females is prolonged, and that this prolongation occurs at all the stages of oocyte development. Since the ovaries of the bobbed females synthesize less rRNA per unit time, it is likely that this prolongation allows the egg chambers of the bobbed females to normalize their RNA content. When they achieve a given RNA content, they proceed to the next stage of development.

THE INFLUENCE OF GROWTH HORMONE ON THE NUCLEIC ACID CONTENT OF RAT LIVER AND MUSCLE

1956 ◽  
Vol 13 (4) ◽  
pp. 429-432 ◽  
Author(s):  
BARBARA J. GRAY
Keyword(s):  
Skeletal Muscle ◽  
Growth Hormone ◽  
Nucleic Acid ◽  
Rat Liver ◽  
Ribonucleic Acid ◽  
Acid Content ◽  
Deoxyribonucleic Acid ◽  
Female Rats ◽  
Nucleic Acid Content ◽  
Pituitary Growth Hormone

SUMMARY Adult female rats were treated with purified pituitary growth hormone for 9 days, and the nucleic acid content of the liver and skeletal muscle determined. An increase was observed in the concentration of muscle ribonucleic acid, expressed per gram of nitrogen, as a result of the treatment. There were no changes in the ribonucleic acid concentration of liver. No changes were observed in the concentration of deoxyribonucleic acid in muscle or liver.

scholarly journals Ameliorating effects of Vit-C on protein and nucleic acid content in dimecron intoxicated chick embryos

2016 ◽  
Vol 2 ◽  
pp. 20-27
Author(s):  
Biplab Kumar Behera ◽  
Keyword(s):  
Nucleic Acid ◽  
Toxic Effect ◽  
Quantitative Study ◽  
Acid Content ◽  
Nucleic Acid Content ◽  
Chick Embryos ◽  
Dna And Rna ◽  
Hen’S Egg ◽  
Made In ◽  
Vit C

Dimecron when introduced into the fertilized hen’s egg at a certain dose before incubation shows a characteristic and interesting feature which has been studied and discussed. A quantitative study of proteins from different organs viz. liver, kidney and brain has been made in the present study. A significant reduction in the quantity of the protein of all the organs is observed. The study witnessed the activity of DNA and RNA that undergoes a decline in its quantity by the action of the pesticide. The toxic effect of pesticides is recovered by the use of ameliorating agent like Vit C. Keywords: Atropine, DNA, organophosphate, protein, RNA, Vit-C.

scholarly journals THE RIBONUCLEIC ACID AND DEOXYRIBONUCLEIC ACID CONTENT OF MONONUCLEAR LEUKOCYTES OF DIFFERENT SIZES STUDIED BY ULTRAVIOLET CYTOPHOTOMETRY

1973 ◽  
Vol 21 (7) ◽  
pp. 628-633 ◽  
Author(s):  
ALFREDO MARIANO GARCIA ◽  
PATRICIA A. N. SULLIVAN
Keyword(s):  
Nucleic Acid ◽  
Cell Size ◽  
Dna Content ◽  
Random Error ◽  
Acid Content ◽  
Deoxyribonucleic Acid ◽  
Nucleic Acid Content ◽  
Mononuclear Leukocytes ◽  
Total Nucleic Acid ◽  
Dna And Rna

Rat mononuclears (lymphocytes and monocytes) were studied for total nucleic acid content by means of ultraviolet cytophotometry. Another set was treated with ribonuclease, and deoxyribonucleic acid (DNA) was measured using the same technique. It was found that total nucleic acid content (DNA and RNA) increases linearly with cell size from about 20 units in lymphocytes having 5 µ in diameter up to around 30 units in cells having 12-14 µ in diameter; this is to say, an almost 50% increase for a 6-7-fold enlargement. After ribonuclease treatment, however, the value of the integrated extinction (DNA) tends to remain constant for different cell sizes. A 650% variation in area is accompanied by a DNA change of less than 6%. The differences between treated and nontreated cells are nonsignificant for populations having up to 7.0-7.5 µ in diameter, which implies that small lymphocytes either have a negligible amount of RNA or that the instrument is not sensitive enough to detect it (less than 7% of the DNA content, this figure being the random error of our technique). These differences become highly significant for mononuclears having 8 µ or more in diameter. Therefore, while DNA tends to be constant and independent from cell size, RNA content tends to be harmoniously inconstant, since it is correlated with cell (and nuclear) size and degree of chromatin diffusion.

Changes in DNA and RNA in the rat adenohypophysis following bilateral adrenalectomy, sham adrenalectomy, and the chronic injection of cortisol

1968 ◽  
Vol 46 (3) ◽  
pp. 431-439 ◽  
Author(s):  
Jacob Kraicer ◽  
Su Chiau Cheng
Keyword(s):  
Nucleic Acid ◽  
Feedback Control ◽  
Acid Content ◽  
Transient Increase ◽  
Bilateral Adrenalectomy ◽  
Nucleic Acid Content ◽  
Dna And Rna ◽  
Rna Content ◽  
Chronic Injection

Changes in adenohypophyseal DNA and RNA content were determined as a function of time following adrenalectomy, sham adrenalectomy, and the chronic injection of cortisol. The stess of operation resulted in a transient increase in adenohypophyseal nucleic acid content, whereas the increase in secretion of ACTH induced by feedback control did not. An attempt is made to correlate the changes in nucleic acid content with the concurrent changes in the intensity of biosynthesis of ACTH.

Sign in / Sign up

Export Citation Format

Share Document