scholarly journals Female Urethral Disease: A Contemporary Review of Presentation, Diagnosis and Current Management Strategies

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
: Cope Z ◽  
Anglin C ◽  
Dryden A ◽  
Hawthorne J ◽  
Choi KBY

Background: Female urethral diseases are sparsely discussed within the literature when compared to urethral diseases affecting men. While, the male urethra is impacted more frequently secondary to the comparative increase in average length, presence of the prostate and considerations of carrying genetic material-disease process of the female urethra impose significant distress to affected patients and also potential for malignancy. The clinical presentation and management strategies often differs from the male counterpart and therefore it is important to consider disease processes of the female urethra unto their own right for evaluation and successful management. It is to that end this publication is put forth.

2020 ◽  
Vol 11 ◽  
pp. 298
Author(s):  
Saleh Salah Safi ◽  
Khaled Murshed ◽  
Arshad Ali ◽  
Surjith Vattoth ◽  
Abdulrazzaq Haider ◽  
...  

Background: Rosai-Dorfman disease (RDD) is an idiopathic nonneoplastic lymphadenopathy disorder which is characterized by lymph node enlargement, but it may also presents primarily involving a variety of extranodal sites, including central nerves system and craniospinal axis. This study reports five cases of craniospinal RDD, with review of epidemiology, clinical presentation, imaging, and histopathological features with current management strategies. Case Description: Five cases of RDD are diagnosed at Hamad General Hospital, Qatar, during 2013–2018. Two cases had dural-based cranial lesions with overlying cranial involvement while three cases were having extradural thoracic spine lesions. All cases underwent surgical intervention and confirmed by histopathology. Conclusion: Craniospinal RDD is a rare clinical presentation and poses significant diagnostic challenges preoperatively due to its similarity with other neoplastic or inflammatory diseases. Surgical option to remove compressive neural pathology provides a good clinical outcome with no recurrence in long-term follow-up.


2005 ◽  
Vol 24 (6) ◽  
pp. 17-24 ◽  
Author(s):  
Cynthia Mundy

Jaundice caused by hemolysis continues to challenge practitioners caring for infants in the NICU. Bilirubin levels can rise quickly in the first days of life, and interventions must be prompt to prevent side effects related to hyperbilirubinemia. Conventional treatments such as hydration and phototherapy are common, but new studies suggest that use of intravenous immunoglobulin (IVIG) as an additional treatment may prevent the need for exchange transfusion in some babies. This article presents a case study of an infant with blood-type incompatibility treated successfully with multiple doses of IVIG, discusses the pathophysiology and clinical presentation of hemolytic jaundice, and reviews current management strategies for this disease.


2017 ◽  
Vol 10 (2) ◽  
pp. 196-200 ◽  
Author(s):  
KR Indushekar ◽  
Raju U Patil ◽  
Rajesh T Anegundi ◽  
Kumar R Gujjar

ABSTRACT Pemphigus is a chronic mucocutaneous disease that initially manifests in the form of intraoral blisters which spread to other mucous membrane and skin. This study describes an unusual case of chronic generalized childhood pemphigus disease in an 11-year-old girl, who presented with multiple vesicles all over her body. Such a condition is seen more often in older people rather than children. It is crucial for dental professionals to be familiar with the diagnosis of bullous skin diseases in children and adolescents, especially in its initial stages in order to prevent the serious consequences and morbidity. The article highlights clinical presentation, histopathology, and successful management strategies useful for pediatric dental practice. How to cite this article Patil RU, Anegundi RT, Gujjar KR, Indushekar KR. Childhood Occurrence of Pemphigus. Int J Clin Pediatr Dent 2017;10(2):196-200.


2001 ◽  
Vol 76 (8) ◽  
pp. 813-822 ◽  
Author(s):  
Jassim Al Suwaidi ◽  
Stuart T. Higano ◽  
David R. Holmes ◽  
Amir Lerman

Author(s):  
Haider Karar ◽  
Muhammad Amjad Bashir ◽  
Abdul Khaliq ◽  
Muhammad Jaffar Ali ◽  
Reem Atalla Alajmi ◽  
...  

2021 ◽  
Author(s):  
Lin Chun-Yi ◽  
Diann Achor ◽  
Amit Levy

Candidatus Liberibacter asiaticus (CLas), the devastating pathogen related to Huanglongbing (HLB), is a phloem-limited, fastidious, insect-borne bacterium. Rapid spread of HLB disease relies on CLas propagates efficiently in its vector, the Asian citrus psyllid, Diaphorina citri, in a circulative manner. Understanding the intracellular lifecycle of CLas in psyllid midgut is fundamental to improve current management strategies. Using a microscopic approach within CLas-infected insect midgut, we observed the entry of CLas into gut cells inside vesicles by endocytosis, termed Liberibacter containing vacuoles (LCVs). Endocytosis is followed by the formation of endoplasmic reticulum-related and replication permissive vacuoles (rLCVs). rLCVs then further develop into bigger double membrane autophagosome-like structure, termed autophagy-related vacuole (aLCV). Vesicles, containing CLas egress from aLCV and fuse with the cell membrane. Immunolocalization studies showed that CLas employs endo/exocytosis-like mechanisms that mediates bacterial invasion and egress. Upregulation of autophagy-related genes indicated subversion of host autophagy by CLas in psyllid vector to promote infection. These results indicate that CLas interacts with host cellular machineries to undergo a multistage intracellular cycle through endocytic, secretory, autophagic and exocytic pathways via complex machineries. Potential tactics for HLB controlling can be made depending on further investigations on the knowledge of the molecular mechanisms of CLas intracellular cycle.


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