scholarly journals Consanguinity, Maternal Age, and Maternal Diabetes as Potential Risk Factors for Congenital Heart Diseases: A Nested Case Control Study from Saudi Arabia

2017 ◽  
Vol 2 (2) ◽  
Author(s):  
Shoukri MM
Keyword(s):  
Maternal Age ◽  
Congenital Heart ◽  
Case Control Study ◽  
Heart Diseases ◽  
Maternal Diabetes ◽  
Case Control ◽  
Congenital Heart Diseases ◽  
Potential Risk Factors ◽  
Nested Case Control ◽  
Control Study

Congenital heart diseases and parental occupational exposure in a Hungarian case‐control study in 1997 to 2002

2020 ◽  
Author(s):  
Vince Fazekas‐Pongor ◽  
Melinda Csáky‐Szunyogh ◽  
Mónika Fekete ◽  
Ágota Mészáros ◽  
Károly Cseh ◽  
...  
Keyword(s):  
Occupational Exposure ◽  
Congenital Heart ◽  
Case Control Study ◽  
Heart Diseases ◽  
Case Control ◽  
Congenital Heart Diseases ◽  
Hungarian Case ◽  
Parental Occupational Exposure ◽  
Control Study

scholarly journals Risk Factors Associated with Congenital Heart Disease in Patients Presenting to Aljalila Cardiology Clinic between January 2020- May 2020: A Case Control Study

2021 ◽  
pp. 1-6
Author(s):  
Samah Alasrawi ◽  
◽  
Hessa Almansoori ◽  
Keyword(s):  
Risk Factors ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Maternal Smoking ◽  
Congenital Heart ◽  
Case Control Study ◽  
Maternal Diabetes ◽  
Case Control ◽  
Cardiology Clinic ◽  
Control Study

Objective: To investigate the association of maternal diabetes, maternal smoking and syndromes with congenital heart disease (CHD) in patients attending Aljalila cardiology clinic between January 2020 and May of 2020. Methods: A case control study to assess the association of maternal diabetes, maternal smoking and syndromes with CHD. All patients that presented to the clinic between January 2020 and May of 2020 were included. An interviewer administered questionnaire was used to record the presence of maternal diabetes, maternal smoking, and the type of syndrome and type of CHD. Patients with CHD were included in the case group and patients who did not have CHD were in the control group. Age, gender, and nationality were also collected from the hospital records. Fisher exact test and logistic regression was used to analyze the results. Results: A total of 177 cases and 211 controls were recruited. All the risk factors increase the risk of CHD, with maternal diabetes (OR 6.3, 95% CI 2.7-14.6) having the strongest association, then syndromes (OR 5.1, 95% CI 2.3-11.3) and lastly maternal smoking (OR 4.0, 95% CI 1.0-16.3). The most common type of CHD is ventricular septal defect. Conclusion: Maternal diabetes, maternal smoking and syndromes are significant risk factors of CHD in children visiting Aljalila cardiology clinic. Action needs to be taken in order to decrease these risk factors and so, decrease the incidence of CHD in the future. Clearly, more research is needed in order to identify other risk factors for patients in the United Arab Emirates (UAE)

scholarly journals Analysis of the causes and influencing factors of fetal loss in advanced maternal age: a nested case-control study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xiaomei Wang ◽  
Yuan Lin ◽  
Zhaozhen Liu ◽  
Xinxin Huang ◽  
Rongxin Chen ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Maternal Age ◽  
Case Control Study ◽  
Fetal Loss ◽  
Advanced Maternal Age ◽  
Case Control ◽  
High School Education ◽  
Factors Influencing ◽  
Nested Case Control ◽  
Control Study

Abstract Background The risk of fetal loss is higher among ≥35-year-olds than younger women. The present study aimed to explore the causes and factors influencing fetal loss in advanced maternal age (AMA). Methods AMA women with singleton fetuses (< 14 gestational weeks) who underwent their first prenatal examination in the Obstetrics Department of Fujian Maternity and Child Health Hospital from December 2018 to June 2020 were included in this cohort study. Those who terminated the pregnancy before 14 gestational weeks were excluded. A baseline survey was conducted, and follow-up was carried out until the termination of the pregnancy. Clinical data were extracted to analyse the causes of fetal loss among them. In the nested case-control study, the AMA women with fetal loss were enrolled as the case group, and women without fetal loss in the same period were enrolled as the control group, in a 1:2 ratio matched by age and gestational weeks. Logistic regression models were used to analyse the factors influencing fetal loss. Results A total of 239 women with fetal loss and 478 controls were enrolled. The causes of fetal loss were most often fetal factors, followed by maternal factors, umbilical cord factors, and placental factors. Multivariate logistic regression analysis indicated that junior high school education and below (adjusted odds ratio (aOR) = 5.13, 95% confidence interval (CI): 2.19–12.02), senior high school education (aOR = 4.91, 95% CI: 2.09–11.54), residence in a rural area (aOR = 2.85, 95% CI: 1.92–4.25), unemployment (aOR = 1.81, 95% CI: 1.20–2.71), spontaneous abortion history (aOR = 1.88, 95% CI: 1.26–2.80), preterm birth history (aOR = 11.08, 95% CI: 2.90–42.26), hypertensive disorders of pregnancy (aOR = 7.20, 95% CI: 2.24–23.12), and preterm premature rupture of membranes (aOR = 4.12, 95% CI: 1.53–11.11) were risk factors for fetal loss. Conclusions Low educational level, unemployment, abnormal pregnancy/labor history, and pregnancy complications were correlated with the incidence of fetal loss in AMA. Thus, early identification as well as a targeted intervention, should be conducted.

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