A clinical case of face and scalp skin lesions in a patient who has undergone COVID-19

2021 ◽  
Vol 20 (5) ◽  
pp. 43
Author(s):  
I.M. Khismatulina ◽  
E.V. Faizullina ◽  
E.S. Gusarova
Keyword(s):  
Clinical Case ◽  
Skin Lesions ◽  
Scalp Skin

scholarly journals Case for diagnosis

2012 ◽  
Vol 87 (6) ◽  
pp. 933-935 ◽  
Author(s):  
Iolanda Conde Fernandes ◽  
Madalena Sanches ◽  
Rosário Alves ◽  
Manuela Selores
Keyword(s):  
Clinical Features ◽  
Rare Variant ◽  
Clinical Case ◽  
Dermatitis Herpetiformis ◽  
Skin Lesions ◽  
Atypical Presentation ◽  
Excellent Response

We report a clinical case of a rare variant of pemphigus - pemphigus herpetiformis - which combines the clinical features of dermatitis herpetiformis with the immunological findings of pemphigus. Due to its atypical presentation, it is frequently misdiagnosed as dermatitis herpetiformis. It is basically characterized by the herpetiform pattern of skin lesions, severe pruritus and by the presence of eosinophilic spongiosis confirmed on histopathology. We call attention to the excellent response to dapsone.

scholarly journals Canine pemphigus folliaceus: report of five clinical case

2018 ◽  
Vol 52 (4) ◽  
pp. 273 ◽  
Author(s):  
M. V. LIAPI (Μ.Β. ΛΙΑΠΗ) ◽  
M. N. SARIDOMICHELAKIS (Μ.Ν. ΣΑΡΙΔΟΜΙΧΕΛΑΚΗΣ) ◽  
A. F. KOUTINAS (Α. Φ. ΚΟΥΤΙΝΑΣ) ◽  
S. LEKKAS (Σ. ΛΕΚΚΑΣ)
Keyword(s):  
Complete Resolution ◽  
Clinical Case ◽  
Spontaneous Remission ◽  
Skin Lesions ◽  
Response To Treatment ◽  
Allergic Dermatitis ◽  
Lost To Follow Up ◽  
Cleft Formation ◽  
Upper Third

Pemphigus folliaceus (PF), which is considered the most common autoimmune skin disease in the dog, is associated with the formation of autoantibodies directed against the desmosomes of the upper third of the epidermis, that result in loss of keratinocyte adhesion (acantholysis) and subsequent epidermal cleft formation. The clinical and histopathological findings, along with the response to treatment in 5 PF cases, either idiopathic (3/5) or secondary to trimethoprim-sulfonamides (1/5) and to allergic dermatitis (1/5), are presented and discussed, accordingly. All the 5 dogs exhibited hypotrichosis-alopecia (4/5), erythema (4/5), vesicles (1/5), pustules (5/5), crusts (5/5), epidermal collarettes (3/5), excoriations (1/5), erosions (3/5), ulcers (1/5), fissures (1/5), lichenification, thickening and folding of the skin (1/5), and footpad hyperkeratosis (1/5), that were pruritic in 3 of them. These lesions were located on the head (4/5), pinnae (4/5), limbs (3/5), body trunk (3/5) and the footpads (2/5). Diagnosis was based on the results of lesionai histopathology where the most striking finding was the presence of subcorneal pustules filled with normally looking neutrophils and acanthocytes. Moreover, pustule or crust cytology that was carried out in 3 cases, revealed clusters of acantholytic cells in 2 dogs. The treatment, that was instituted in 2/5 dogs and resulted in a complete resolution of skin lesions, was based on prednisolone in immunosuppressive dosage along with azathioprine (PF secondary to allergic dermatitis), or on a combination of dapsone, Oxytetracycline and vitamin E (idiopathic PF). The remaining 3 cases were left untreated, because one showed a spontaneous remission following withdrawal of the offending medication and the other 2 were lost to follow-up.

scholarly journals Linear porokeratosis: a case report

2012 ◽  
Vol 4 (3) ◽  
pp. 105-112
Author(s):  
Slobodan Stojanović ◽  
Marina Jovanović ◽  
Nada Vučković ◽  
Siniša Tasić ◽  
Keyword(s):  
Clinical Case ◽  
Local Treatment ◽  
Clinical Manifestations ◽  
Skin Lesions ◽  
Skin Carcinoma ◽  
Imiquimod Cream ◽  
Lines Of Blaschko ◽  
Cornoid Lamella ◽  
Co2 Laser Ablation ◽  
Timely Treatment

Abstract Porokeratosis is a rare genodermatosis based on chronic keratinization disorder histologically characterized by the presence of a cornoid lamella and various clinical manifestations. Five most commonly described types of poroketarosis are porokeratosis of Mibelli or ”classic” porokeratosis, disseminated superfi cial actinic porokeratosis, disseminated palmoplantar porokeratosis, linear porokeratosis, and punctate porokeratosis. In all of the fi ve clinical types of porokeratosis described today, cases of planocellular skin carcinoma are described, except in punctate type cases. Use of topical CO2 laser ablation, cryotherapy and topical use of 5% Imiquimod cream, have shown favorable effects in local treatment of porokeratosis. The authors present a clinical case of a girl suffering from linear porokeratosis over the course of the last four years, spreading on the inside of her right arm along the lines of Blaschko. Linear porokeratosis was histologically confi rmed by biopsy of skin lesions and dermoscopy. Dermoscopic fi ndings, used as an auxiliary method, also indicated linear porokeratosis. Successful liquid nitrogen cryotherapy prompted the authors to present a case in which the applied treatment proved to be successful, but also to emphasize the need for timely treatment in order to prevent malignant alterations of these changes.

SYSTEMIC LUPUS ERYTHEMATOSUS: REVIEW OF MODERN METHODS OF DIAGNOSIS, TREATMENT AND DESCRIPTION OF THE CLINICAL CASE

2021 ◽  
pp. 57-65
Author(s):  
Nadezhda V. Zhuravleva ◽  
Louise M. Karzakova ◽  
Tatyana L. Smirnova ◽  
Sergey I. Kudryashov ◽  
Tatyana S. Lutkova ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Rheumatoid Factor ◽  
Lupus Erythematosus ◽  
Clinical Case ◽  
Skin Lesions ◽  
Blood Analysis ◽  
Federal State ◽  
Systemic Lupus ◽  
Initial Examination ◽  
Immunological Disorders

A clinical case of systemic lupus erythematosus (SLE) is presented. Since childhood the patient had preclinical lupus: leukopenia, anemia, photoallergy, vasculitis, and serological changes a-SS-A (+++), but at that time the findings did not meet the criteria for SLE. At the initial examination of the woman at the age of 24 years, a clinical blood test revealed hemoglobin 101 g/l, leukopenia 3.2×109/l, ESR 41 mm/h, hyper-γ-globulinemia 29%. The immunological blood analysis revealed a-DNA (+++), a-SS-A (+++), aSm (+++), aRNP (+++). The diagnosis was "Systemic lupus erythematosus of chronic (at the beginning) course, activity of the 1st degree (2 points by the SLEDA scale): with hematological disorders (leukopenia), immunological disorders (ANA+)". Metypred was administered at a dose of 16 mg/day, followed by the dose reduction to 6 mg/day and Plaquenil 400 mg/day. The woman received inpatient and outpatient treatment, repeatedly consulted in the Federal State Budgetary Institution "V.A. Nasonova Research Institute" under the Russian Academy of Medical Sciences. At the age of 26, the diagnosis was made: "Systemic lupus erythematosus, grade 2 activity with skin lesions of the type of subacute cutaneous lupus, cheilitis, lymphadenopathy", blood tests revealed leukopenia, lymphopenia, anemia, as well as immunological disorders: a-n DNA 93.4 u/ml, aSm > 200 u/ml, aRo > 200 u/ml, C3 0.63 g/l, rheumatoid factor 69.5 mIU/ml, ANA (Нер-2) 1/640 Sp. A complex therapy was performed with the use of Metypred, Cyclophosphane and Azathioprine. Against the background of the therapy, the patient's condition is stable, but immunological disorders are preserved: persistent high positivity for aRo-SS-A and the presence of the rheumatoid factor. The case demonstrates the need for an in-depth examination of women with anemia of unknown origin in combination with leukopenia to exclude systemic diseases of the connective tissue.

scholarly journals Cutaneous lesions associated with coronavirus-induced vasculitis in a cat with feline infectious peritonitis and concurrent feline immunodeficiency virus infection

2005 ◽  
Vol 7 (4) ◽  
pp. 233-236 ◽  
Author(s):  
Martha J Cannon ◽  
Malcolm A Silkstone ◽  
Anja M Kipar
Keyword(s):  
Feline Immunodeficiency Virus ◽  
Clinical Case ◽  
Skin Lesions ◽  
Cutaneous Lesions ◽  
Feline Infectious Peritonitis ◽  
Abdominal Organs ◽  
Target Organs ◽  
Feline Immunodeficiency Virus Infection ◽  
Immunodeficiency Virus ◽  
Feline Coronavirus

This report describes a clinical case of feline infectious peritonitis (FIP) with multisystemic involvement, including multiple nodular cutaneous lesions, in a cat that was co-infected with feline coronavirus and feline immunodeficiency virus. The skin lesions were caused by a pyogranulomatous-necrotising dermal phlebitis and periphlebitis. Immunohistology demonstrated the presence of coronavirus antigen in macrophages within these lesions. The pathogenesis of FIP involves a viral associated, disseminated phlebitis and periphlebitis which can arise at many sites. Target organs frequently include the eyes, abdominal organs, pleural and peritoneal membranes, and central nervous tissues, but cutaneous lesions have not previously been reported.

scholarly journals Tinea: Incidence during Magh Mela

2018 ◽  
Vol 5 (4) ◽  
pp. 993
Author(s):  
Upma Narain ◽  
Ashok Kumar Bajaj ◽  
Arun Kant
Keyword(s):  
Skin Lesions ◽  
Microsporum Canis ◽  
Gram Stain ◽  
Trichophyton Verrucosum ◽  
Short Period ◽  
Scopulariopsis Brevicaulis ◽  
Tinea Versicolor ◽  
Scalp Skin ◽  
Macroscopic Examination ◽  
Ganga Water

Background: Dermatophytosis refer to superficial fungal infection of keratinized tissues caused by keratinophilic dermatophytes. It is common in tropics and may present in epidemic proportions in areas with high rates of humidity.Methods: The retrospective study was carried out from January 2018 to February 2018 at Allahabad. Gram stain, KOH examination and culture were carried out in 300 cases.Results: Out of the 300 suspected cases authors identified, 263 cultures tested positive. The macroscopic examination of the scalp, skin and the nails of these 36 patients further revealed 50.20% Tinea corporis, 17.87% Tinea cruris, 11.02 % Tinea mannum, 8.74% Tinea pedis, 7.99% onychomycosis, 3.42% Tinea versicolor and 0.76% Tinea capitis. Culture examinations revealed 52.47% Trychophyton mentagrophyte, 34.98% Trichyopyton rubrum, 3.80% Trychophyton violaceum, 3.43% Malessesia, 2.28% Scopulariopsis brevicaulis, 1.52% Trichophyton verrucosum, 0.76% Microsporum canis and 0.76% Epidermophyton flucossum.Conclusions: The study concludes that in a short period of Magh Mela authors got a large number of skin patients because of their belief that the holiness Ganga water will cure skin problems by itself. Some of the patients were found infected from the beginning and some gather infections during their stay in the mela period. Therefore, a prompt recognition of skin lesions and the identification of these superficial fungi are required for judicious management.

scholarly journals Anaplastic Large Cell Lymphoma with Generalized Skin Lesion in Childhood: Clinical Case

2020 ◽  
Vol 19 (6) ◽  
pp. 477-482
Author(s):  
Timur T. Valiev ◽  
Tatyana S. Belysheva ◽  
Svetlana R. Varfolomeeva
Keyword(s):  
Anaplastic Large Cell Lymphoma ◽  
Clinical Case ◽  
Clinical Laboratory ◽  
Cell Lymphoma ◽  
Large Cell ◽  
Skin Lesions ◽  
Pathological Process ◽  
Practical Significance ◽  
Disease Manifestation ◽  
Large Cell Lymphoma

Background. Anaplastic large cell lymphoma (ALCL) represents 15% of all non-Hodgkin lymphomas (NHL) in children, and it is characterized by aggressive course and involvement of various organs and systems (including skin) in the pathological process. Skin tumors at NHL in childhood are rare. Thus, cases of skin localization are more oftenly diagnosed at ALCL among all morphoimmunologic variants of NHLs. The description of any new case of skin lesions in patients with ALCL has undeniable interest and scientific and practical significance due to its extremely rare frequency.Clinical Case Description. Patient G., 11 years old, has firstly noted inflammatory nodes on the skin of scrotum. The generalization of skin lesions on tibia, face, lymph nodes and bones was recorded due to late admission to the hospital. The inflammatory-necrotic process has been revealed at skin histological examination. Local antiseptic and antibacterial therapies were ineffective. The ALCL was diagnosed on morphoimmunologic re-examination of the skin. Life expectancy after disease manifestation to patient’s death was 6 months.Conclusion. Rare cases of skin involvement at ALCL require mandatory histological and immunohistochemical examinations. Second biopsy with reconsideration of histological preparations in the reference center may be necessary due to clinical-laboratory picture of the inflammatory process accompanying the tumor itself.

scholarly journals ULCERATIVE-NECROTIZING ANGIITIS ON A BACKGROUND OF RECEPTION OF LENVATINIB IN THYROID CANCER

2019 ◽  
Vol 22 (1-2) ◽  
pp. 29-32
Author(s):  
Ekaterina V. Orlova ◽  
O. V Grabovskaya ◽  
L. M Smirnova ◽  
L. A Shestakova ◽  
N. I Melikova ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Growth Factor ◽  
Clinical Case ◽  
Skin Lesions ◽  
Tyrosine Kinase Receptor ◽  
Targeted Drugs ◽  
Skin Reactions ◽  
Vascular Growth ◽  
Vascular Growth Factor ◽  
Different Types

The information about modern targeted drugs used in chemotherapy regimens for different types of cancer is presented. The mechanisms of pathogenesis of the development of undesirable skin reactions in the presence of tyrosine kinase receptor inhibitors are described. The clinical case of a rarely occurring reaction to drugs inhibitors of vascular growth factor in the form of ulcerative-necrotic skin lesions in a 63-year-old patient is presented.

scholarly journals Urticaria-like rash in a patient with COVID-19 associated pneumonia of moderate severity: aspects of pathogenesis

2020 ◽  
Vol 23 (2) ◽  
pp. 109-114
Author(s):  
Ekaterina V. Orlova ◽  
L. M. Smirnova ◽  
N. I. Melikova ◽  
K. Yu. Popova
Keyword(s):  
Clinical Case ◽  
Case Reports ◽  
Clinical Manifestations ◽  
Skin Lesions ◽  
Infection Process ◽  
Moderate Severity ◽  
Skin Manifestations ◽  
General Weakness

In mid 2020, the number of new coronavirus (COVID-19) cases has exceeded globally six million. The clinical manifestations of COVID-19 infection are numerous mostly causing damage to the bronchopulmonary system in the form of a dry cough, rhinitis, dyspnea, fever, myalgia, and general weakness. Skin manifestations of COVID-19 are rare and currently include five types of skin lesions occurring during the infection process, which are reliably recorded in only a limited number of case reports and certain analytical publications. This article describes the clinical case of a 28-year-old patient with urticaria-like disseminated rash and confirmed COVID-19-associated pneumonia.

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