Subtraction CT angiopulmonographic assessment of the vascular bed and lung perfusion in patients with chronic thromboembolic pulmonary hypertension: A pilot study

Aim. To evaluate the vascular bed and lung perfusion in patients with chronic thromboembolic pulmonary hypertension (CTEPH) by computed tomography (CT) and to compare the severity of pulmonary arterial (PA) thrombotic lesions concurrent with parenchymal perfusion disorders with angiopulmonographic findings and clinical and hemodynamic characteristics. Subjects and methods. In the period from November 2015 to May 2016, 22 patients (7 men, 15 women) aged 27 to 67 years with a verified diagnosis of CTEPH were examined using an Aquilion ONE VISION Edition 640 (Toshiba Medical Systems, Japan) CT scanner with a 320-row detector. Perfusion defect in this study was evaluated with the new software allowing one to combine contrast and contrast-free images by a subtraction method. CT data analysis included visual assessment of the vascular bed and lung parenchyma and quantitative assessment with perfusion map construction and semi-automatic determination of the obstruction index (OI) and perfusion defect index (PDI). OI was compared with PDI and mean LA pressure according to the data of right heart catheterization and 6-minute walk test. Results. A statistically significant correlation was found between OI and PDI in patients with CTEPH (Pearson r=0.56; p=0.0065). There were no relationships between mean LA pressure and vascular perfusion indices (OI and PDI) or between vascular perfusion parameters and 6-minute walk test results. Conclusion. CT angiopulmonography in conjunction with pulmonary perfusion assessment (within one study) allows evaluation of the severity of vascular lesions and perfusion disorders and determination of the efficiency of treatment in patients with CTEPH.

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SUBTRACTION PULMONARY ANGIOGRAPHY IN DIAGNOSIS OF CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION

Medical Visualization ◽

10.24835/1607-0763-2018-4-40-49 ◽

2018 ◽

pp. 40-49

Author(s):

T. N. Veselova ◽

A. Yu. Demchenkova ◽

T. V. Martynyuk ◽

N. M. Danilov ◽

S. K. Ternovoy ◽

...

Keyword(s):

Pulmonary Hypertension ◽

Pulmonary Artery ◽

Pulmonary Artery Pressure ◽

Chronic Thromboembolic Pulmonary Hypertension ◽

Pulmonary Angiography ◽

Walk Test ◽

Artery Pressure ◽

Thromboembolic Pulmonary Hypertension ◽

6 Minute Walk Test ◽

Minute Walk

Purpose. To assess the state of the vascular bed and perfusion of the lungs in patients with chronic thromboembolic pulmonary hypertension (CTEPH) by the method of subtraction computed tomography (CT).Materials and methods. Between November 2015 and May 2018, 65 patients with diagnosis of CTEPH were examined. All patients were examined on a computer tomograph Aquilion ONE 640 VISION Edition (Toshiba Medical Systems) with 320 rows of detectors, slice thickness – 0,5 mm. Assessment of perfusion disorders was carried out using new software, which allows combining contrast and noncontrast images by subtraction. Were analyzed parameters of the parenchyma, blood supply and perfusion status with the calculation of indices of obstruction and perfusion disorders. The obstruction index was compared with the index of perfusion abnormalities, a 6-minute walk test, and mean pulmonary artery pressure according to the right heart catheterization data. Results. The significant correlation was found between the obstruction index and the index of perfusion disorders in patients with CTEPH (r = 0.605; p = 0.000001). Interrelations between vascular-perfusion indices (an obstruction index and an index of perfusion disorders), mean pulmonary artery pressure and distance in a 6-minute walk test were not revealed.Conclusion. Subtraction CT pulmonary angiography allows to assess the severity of vascular lesion and perfusion disorders within a single study, also determine the effectiveness of treatment in patients with CTEPH.

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Does the determination of plasma norepinephrine concentration after 6′ minute walk test improve risk stratification in congestive heart failure?

European Journal of Heart Failure ◽

10.1016/s1388-9842(00)80332-3 ◽

2000 ◽

Vol 2 ◽

pp. 94-94 ◽

Cited By ~ 1

Author(s):

C. Zugck ◽

C. Schellong ◽

S. Körber ◽

A. Kirschke ◽

F. Chwallek ◽

...

Keyword(s):

Heart Failure ◽

Congestive Heart Failure ◽

Risk Stratification ◽

Plasma Norepinephrine ◽

Walk Test ◽

Improve Risk Stratification ◽

Norepinephrine Concentration ◽

6 Minute Walk Test ◽

Minute Walk

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The effect of virtual reality exercise on physical fitness

Rehabilitacja Medyczna ◽

10.5604/01.3001.0013.3717 ◽

2019 ◽

Vol 23 (2) ◽

pp. 4-9

Author(s):

Dawid Bedrunka ◽

Katarzyna Buchta ◽

Patryk Szary ◽

Katarzyna Maniakowska ◽

Pawel Kiper ◽

...

Keyword(s):

Virtual Reality ◽

Physical Fitness ◽

Healthy Volunteers ◽

Walk Test ◽

Test Results ◽

Fitness Test ◽

Positive Effects ◽

The Mean ◽

6 Minute Walk Test ◽

Minute Walk

Introduction: The aim of this study was to assess physical fitness (PF) in healthy volunteers using the Senior Fitness Test (SFT) after a series of training sessions in virtual reality (VR) using the X-box 360 Kinect System. Materials and methods: This pilot study consisted of 32 healthy subjects aged 19 to 24 years (12 males and 20 females) with the mean age of 20.6±1.4 years and the mean BMI of 23.29±2.3. The subjects participated in the study for 2 weeks, at a frequency of 4 sessions weekly. Each session comprised 4 Kinect Adventures games: 20 000 Leaks, Curvy Creak, Rally Ball and Reflex Ridge. The Senior Fitness Test was used to assess physical fitness. Results: Analysis of data showed improvement in Arm-Curl (30.0 repetitions (rep.)) vs. 35.8 rep., p<0.001), Chair Stand (26.6 rep. vs. 30.2 rep., p<0.001), Back Scratch (3.1 cm vs. 6.1 cm, p<0.033), Chair Sit-and-Reach (1.0 cm vs. 5.3 cm, p<0.001), Up-and-Go (3.5 sec. vs. 3.2 sec., p<0.001) and 6-Minute Walk Test (731.3 m vs. 747.8.m, p<0.220). Statistically significant improvement was noted in 5 out of 6 STF trials. Only the 6-Minute Walk test results were not statistically significant. Conclusions: Training using a console with the Kinect motion sensor had positive effects on the physical fitness of the healthy volunteers.

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Determination Of Hemodynamic Parameters During 6-Minute Walk Test In Pulmonary Hypertension

10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a4093 ◽

2012 ◽

Author(s):

Vineesha Arelli ◽

Jose Ramos ◽

Kevin McCarthy ◽

Adriano Tonelli ◽

Raed A. Dweik ◽

...

Keyword(s):

Pulmonary Hypertension ◽

Walk Test ◽

Hemodynamic Parameters ◽

6 Minute Walk Test ◽

Minute Walk

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Why to evaluate the functional capacity in PAD patients?

VASA ◽

10.1024/0301-1526/a000852 ◽

2020 ◽

Vol 49 (4) ◽

pp. 275-280

Author(s):

Pavel Poredoš ◽

Mateja K. Jezovnik

Keyword(s):

Quality Of Life ◽

Functional Impairment ◽

Constant Load ◽

Load Test ◽

Walk Test ◽

Treadmill Test ◽

6 Minute Walk Test ◽

Minute Walk

Summary: In patients with peripheral arterial disease (PAD), the ability to perform physical exercise is an essential and most important indicator of a patient’s health and quality of life. In many cases, there exists a discrepancy between lower extremity blood flow, the extent of arterial occlusion shown by morphological investigation and functional impairment. Reversal of lower extremity arterial obstruction with revascularization does not always reverse functional impairment of diseased leg. Further, training exercise and drug treatment can improve functional performance although they are not associated with an improvement in arterial obstruction. Therefore, the determination of functional impairment and its recovery after different therapeutic procedures should be determined using objective tests. The most frequently used functional tests are treadmill exercise testing and a 6-minute walk test. The constant load test, in which results are expressed as a walked distance, does not always permit an accurate assessment of the full range of functional impairment of PAD patients. Recently, as a substitute for a constant-load test, the graded treadmill test is used. With this test, it is possible to identify those individuals with exercise limitations who are not caused only by deterioration of the blood flow of lower limbs. The 6-minute walk test is simple to perform and requires minimal equipment. However, the correlation between the 6-minute walk test and the graded treadmill test is relatively weak, indicating that peak performance on a graded treadmill may reflect different pathophysiological mechanisms of limitations. In conclusion: for the determination of limitations of mobility and quality of life in patients with PAD, objective measures of functional impairment are needed. The determination of functional capacity is related to the quality of life and is a useful tool for investigation of the success of revascularization of peripheral arteries and conservative treatment.

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Determination of 6-minute walk test using accelerometer-based ambulatory monitoring device for the assessment of patient’s progress in cardiac rehabilitation

IFMBE Proceedings - World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany ◽

10.1007/978-3-642-03885-3_150 ◽

2009 ◽

pp. 540-542

Author(s):

Mohanraj Karunanithi ◽

Niranjan Bidargaddi ◽

Antti Sarela

Keyword(s):

Cardiac Rehabilitation ◽

Ambulatory Monitoring ◽

Monitoring Device ◽

Walk Test ◽

6 Minute Walk Test ◽

Minute Walk

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Telemetriás és online nontelemetriás adatok elemzése szívelégtelen betegek fizikai aktivitásának jellemzésére

Orvosi Hetilap ◽

10.1556/650.2017.30824 ◽

2017 ◽

Vol 158 (35) ◽

pp. 1390-1395

Author(s):

Csaba Melczer ◽

László Melczer ◽

Ilona Goják ◽

Attila Kónyi ◽

Sándor Szabados ◽

...

Keyword(s):

Physical Activity ◽

Heart Disease ◽

Electronic Device ◽

Developed Countries ◽

Walk Test ◽

Test Results ◽

Telemetry Data ◽

6 Minute Walk Test ◽

Test Result ◽

Minute Walk

Abstract: Introduction: Several studies have demonstrated that the prevalence of heart disease can be accounted for between 0.4 and 2% in developed countries. Aim: The present study aimed to use the PA% of the telemetry data to estimate the 6-minute walk test result. Method: A total of seventeen patients with heart disease; 3 females and 14 males; age: 57.35 yrs ± 9.54; body mass 98.71 ± 9.89 kg; average BMI 36.69 ± 3.67 were recruited into the study. Using the two sets of values describing physical performance, linear regression was calculated providing a mathematical equation, thus, the Physical Activity % value is used to estimate the distance traveled over a 6-minute walk test. Results: On further data analysis, we have come to the conclusion that the distance walked during the six-minute-long test may be measured by PA% from the data of CRT device. Conclusions: With our method, based on the values received from the physical activity sensor implanted into the resynchronisation devices, changes in patients’ health status could be monitored telemetrically with the assistance from the implanted electronic device. Orv Hetil. 2017; 158(35): 1390–1395.

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