scholarly journals Effect of DGAT1, BTN1A1, OLR1, and STAT1 genes on milk production and reproduction traits in the Czech Fleckvieh breed

2014 ◽  
Vol 59 (No. 2) ◽  
pp. 45-53 ◽  
Author(s):  
J. Rychtářová ◽  
Z. Sztankóová ◽  
J. Kyselová ◽  
V. Zink ◽  
M. Štípková ◽  
...  
Keyword(s):  
Milk Production ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Breeding Value ◽  
Production Traits ◽  
Milk Production Traits ◽  
Heterogeneous Effects ◽  
Reproduction Traits ◽  
Estimated Breeding Value ◽  
The Impact

The impact of polymorphism of the diacylglycerol acyltransferase (DGAT1), butyrophilin (BTN1A1), oxidized low-density lipoprotein receptor (OLR1), and signal transducer and activator of transcription 1 (STAT1) genes on milk production and reproduction traits in 419 Czech Fleckvieh cows was examined using polymerase chain reaction and restriction fragment length polymorphism. The loci DGAT1 and BTN1A1 were observed simultaneously to affect milk production, estimated breeding value of milk production traits, as well as reproduction parameters. Significant differences were found also between genotypes of the STAT1 loci in relation to estimated breeding value of milk production traits. Similar findings in pure dairy breeds suggest that heterogeneous effects of the observed loci can be explained by different genetic backgrounds in various breed populations selected to achieve different commercial goals. Thus, it is necessary to determine variability and influence of a molecular marker in a specific population when considering its inclusion into a breeding programme.  

scholarly journals The effectiveness of genomic selection for milk production traits of Holstein dairy cattle

2020 ◽  
Vol 33 (3) ◽  
pp. 382-389 ◽  
Author(s):  
Yun-Mi Lee ◽  
Chang-Gwon Dang ◽  
Mohammad Z. Alam ◽  
You-Sam Kim ◽  
Kwang-Hyeon Cho ◽  
...  
Keyword(s):  
Genomic Selection ◽  
Milk Production ◽  
Genetic Gain ◽  
Milk Fat ◽  
Breeding Value ◽  
Production Traits ◽  
Milk Production Traits ◽  
Data Set ◽  
Selection For ◽  
Estimated Breeding Value

Objective: This study was conducted to test the efficiency of genomic selection for milk production traits in a Korean Holstein cattle population.Methods: A total of 506,481 milk production records from 293,855 animals (2,090 heads with single nucleotide polymorphism information) were used to estimate breeding value by single step best linear unbiased prediction.Results: The heritability estimates for milk, fat, and protein yields in the first parity were 0.28, 0.26, and 0.23, respectively. As the parity increased, the heritability decreased for all milk production traits. The estimated generation intervals of sire for the production of bulls (L<sub>SB</sub>) and that for the production of cows (L<sub>SC</sub>) were 7.9 and 8.1 years, respectively, and the estimated generation intervals of dams for the production of bulls (L<sub>DB</sub>) and cows (L<sub>DC</sub>) were 4.9 and 4.2 years, respectively. In the overall data set, the reliability of genomic estimated breeding value (GEBV) increased by 9% on average over that of estimated breeding value (EBV), and increased by 7% in cows with test records, about 4% in bulls with progeny records, and 13% in heifers without test records. The difference in the reliability between GEBV and EBV was especially significant for the data from young bulls, i.e. 17% on average for milk (39% vs 22%), fat (39% vs 22%), and protein (37% vs 22%) yields, respectively. When selected for the milk yield using GEBV, the genetic gain increased about 7.1% over the gain with the EBV in the cows with test records, and by 2.9% in bulls with progeny records, while the genetic gain increased by about 24.2% in heifers without test records and by 35% in young bulls without progeny records.Conclusion: More genetic gains can be expected through the use of GEBV than EBV, and genomic selection was more effective in the selection of young bulls and heifers without test records.

scholarly journals To the question of evaluating the efficiency of linear breeding in Simmental cattle breed different origin

2020 ◽  
Vol 197 (6) ◽  
pp. 49-57
Author(s):  
L. Ignat'eva ◽  
A. Konte ◽  
A. Sermyagin
Keyword(s):  
Milk Production ◽  
Milk Yield ◽  
Russian Federation ◽  
Mixed Model ◽  
Breeding Value ◽  
Production Traits ◽  
Fat Percentage ◽  
Foreign Origin ◽  
Simmental Cattle ◽  
The Impact

Abstract. The purpose of the research – to study the impact of related foreign pedigree resources on the Russian population of Simmental cattle. Research Methods. Studies carried out on cows of Simmental breed of different linear origin and genotypes in five regions of Russian Federation: Voronezh, Oryol, Kursk, Belgorod regions and Altayskiy krai, the total number was 35147 cows. EBV estimates were calculated through RENUMF 90, REMLF 90 and BLUPF 90 programs. Evaluation of the components of the variants of genetic and paratypical nature was carried out using the method restricted maximum likelihood – REML. Results. It is established that the largest share for animals foreign origin are 60.7 %, including German-Austrian bloodlines 46.6 % and Holsteins – 14.1 %. 39.3 % of animals are the Russian origin, which 13.5 % representatives of German-Austrian bloodlines, 17.8 % are Holsteins and 8.0 % are from domestic (Russian) bloodlines. In the general population of Simmental breed, the best productivity was shown by cows of German-Austrian bloodlines at the level of 5351 kg of milk with fat percentage 4.00 % and protein percentage 3.19 %. Representatives of German-Austrian bloodlines origin for milk yield showed the estimated breeding value (EBV) for Simmental bulls in the common population by +9.2 kg and fat percentage by +0.012 %. The negative EBV values were obtained for Russian bloodlines by –22.8 kg, and Holstein bloodlines took an intermediate position among all lines (+2.3 kg). The first calving cows, which were in the herd at the time of research, the best milk production traits were found in individuals of foreign origin, both for Holstein (6096 kg of milk with a fat content of 3.96 % and protein 3.23 %), and German-Austrian bloodlines (milk yield 5763 kg, fat 4.04 % and protein 3.19 %), with high estimates of breeding value for milk yield +33.3 kg and +15.2 kg, respectively. Low values of milk productivity among all evaluated animals were observed for animals of Russian bloodlines by 4469 kg milk 3.87 % fat and 3.20 % protein in milk. The first calving cows of Russian origin in foreign bloodlines origin exceeded their peers in Russian Simmental bloodlines in milk production by +608 kg of milk and +0.15 % fat (signed to German-Austrian bloodlines) and +924 kg and +0.06 % fat (signed to Holstein bloodlines). The average values of EBV in these lines, although had low values by –5.6 kg milk for Holstein and by +2.7 kg milk for German-Austrian bloodlines, but was significantly higher than for Russian lines by –12.7 kg milk. Scientific novelty. For the first time, scientific research aimed at improving the system of prediction to breeding abilities of bulls on dairy productivity of daughters based on optimization structure of equations of the mixed model (BLUP, the best linear unbiased prediction) has been carried out for the population Simmental cattle of Russian Federation.

scholarly journals Genomic Loci Affecting Milk Production in German Black Pied Cattle (DSN)

2021 ◽  
Vol 12 ◽  
Author(s):  
Paula Korkuć ◽  
Danny Arends ◽  
Katharina May ◽  
Sven König ◽  
Gudrun A. Brockmann
Keyword(s):  
Milk Production ◽  
Milk Yield ◽  
Lactation Period ◽  
Production Traits ◽  
Linear Regression Models ◽  
Milk Production Traits ◽  
Milk Traits ◽  
Dual Purpose ◽  
A Genome ◽  
Reproduction Traits

German Black Pied cattle (DSN) is an endangered population of about 2,550 dual-purpose cattle in Germany. Having a milk yield of about 2,500 kg less than the predominant dairy breed Holstein, the preservation of DSN is supported by the German government and the EU. The identification of the genomic loci affecting milk production in DSN can provide a basis for selection decisions for genetic improvement of DSN in order to increase market chances through the improvement of milk yield. A genome-wide association analysis of 30 milk traits was conducted in different lactation periods and numbers. Association using multiple linear regression models in R was performed on 1,490 DSN cattle genotyped with BovineSNP50 SNP-chip. 41 significant and 20 suggestive SNPs affecting milk production traits in DSN were identified, as well as 15 additional SNPs for protein content which are less reliable due to high inflation. The most significant effects on milk yield in DSN were detected on chromosomes 1, 6, and 20. The region on chromosome 6 was located nearby the casein gene cluster and the corresponding haplotype overlapped the CSN3 gene (casein kappa). Associations for fat and protein yield and content were also detected. High correlation between traits of the same lactation period or number led to some SNPs being significant for multiple investigated traits. Half of all identified SNPs have been reported in other studies, previously. 15 SNPs were associated with the same traits in other breeds. The other associated SNPs have been reported previously for traits such as exterior, health, meat and carcass, production, and reproduction traits. No association could be detected between DGAT1 and other known milk genes with milk production traits despite the close relationship between DSN and Holstein. The results of this study confirmed that many SNPs identified in other breeds as associated with milk traits also affect milk traits in dual-purpose DSN cattle and can be used for further genetic analysis to identify genes and causal variants that affect milk production in DSN cattle.

Prediction Breeding Value and Genetic Parameter in Iranian Holstein Bulls for Milk Production Traits

2007 ◽  
Vol 11 (1) ◽  
pp. 108-112 ◽  
Author(s):  
Mojtaba Hosseinpour Mashhadi ◽  
Naser Emam Jomeh Kash ◽  
Mohammad Reza Nassiry ◽  
Rasol Vaez Torshizi
Keyword(s):  
Milk Production ◽  
Genetic Parameter ◽  
Breeding Value ◽  
Production Traits ◽  
Milk Production Traits ◽  
Holstein Bulls

scholarly journals Effect of leptin gene polymorphism on the breeding value of milk production traits in Iranian Holstein

animal ◽  
2008 ◽  
Vol 2 (7) ◽  
pp. 999-1002 ◽  
Author(s):  
M. Sadeghi ◽  
M. Moradi Shahr Babak ◽  
G. Rahimi ◽  
A. Nejati Javaremi
Keyword(s):  
Gene Polymorphism ◽  
Milk Production ◽  
Breeding Value ◽  
Production Traits ◽  
Milk Production Traits

scholarly journals Estimation of the breeding value and ranking of holstein-friesian bulls for milk production traits

2018 ◽  
Vol 24 (2) ◽  
pp. 32-38
Author(s):  
Miloš Marinković ◽  
Nenad Mićić ◽  
Marina Lazarević ◽  
Vlada Pantelić ◽  
Predrag Perišić ◽  
...  
Keyword(s):  
Milk Production ◽  
Breeding Value ◽  
Production Traits ◽  
Milk Production Traits ◽  
Holstein Friesian

scholarly journals Relationships of growth hormone gene and milk protein polymorphisms to milk production traits in Simmental cattle

1997 ◽  
Vol 64 (1) ◽  
pp. 47-56 ◽  
Author(s):  
MOHAMMED FALAKI ◽  
ALBERTO PRANDI ◽  
CESARE CORRADINI ◽  
MYRIAM SNEYERS ◽  
NICOLAS GENGLER ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Gene Polymorphism ◽  
Milk Production ◽  
Restriction Enzyme ◽  
Milk Protein ◽  
Breeding Value ◽  
Production Traits ◽  
Milk Production Traits ◽  
Gh Gene ◽  
Protein Polymorphisms

The importance of milk proteins and the positive effect of administration of growth hormone (GH) on milk production, and the presence in some dairy cattle lines of greater GH concentrations prompted us to examine the presence of restriction fragment length polymorphism at the GH gene using the restriction enzyme TaqI and to investigate associations between this polymorphism in Simmental cows and bulls, as well as milk protein variants in Simmental cows, and milk production traits. Blood and milk were sampled from 279 Italian Simmental cows and semen was collected from 148 bulls of the same breed. Two fragment bands, denoted A and B, of 6200 and 5200 bp respectively, were examined and three patterns, AA, AB and BB, were found in both animal samples. All variants previously reported in other studies, for κ, β, and αs1-caseins, and β-lactoglobulin, were found in the cows' samples. For the cows' samples, a BLUP (Best Linear Unbiased Predictor) analysis of results was performed using a REML (Restricted Maximum Likelihood) program and known heritabilities, whereas for bulls we have performed a General Linear Model analysis. The effect of GH gene polymorphism, using TaqI restriction enzyme, on milk production traits was not significant, but bulls of BB pattern had a higher breeding value for milk yield than AA bulls (P<0·05). For the κ-casein genotypic effects, cows of AB genotype gave milk with 1·53±0·70 g/kg less fat than cows of AA genotype. In addition, breeding values for milk protein content were significantly higher in BB bulls, with 0·87±0·32 and 0·71±0·34 g/kg more milk protein than AA and AB bulls respectively. Thus, our results revealed a GH gene polymorphism and indicated significant effects of milk protein polymorphisms on milk production traits in the Italian Simmental breed.

scholarly journals Short Communication: Effect of Leptin Gene Polymorphisms on Breeding Value for Milk Production Traits

2004 ◽  
Vol 87 (11) ◽  
pp. 3925-3927 ◽  
Author(s):  
Z. Madeja ◽  
T. Adamowicz ◽  
A. Chmurzynska ◽  
T. Jankowski ◽  
J. Melonek ◽  
...  
Keyword(s):  
Milk Production ◽  
Gene Polymorphisms ◽  
Short Communication ◽  
Breeding Value ◽  
Production Traits ◽  
Milk Production Traits ◽  
Communication Effect
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