Prevalence of Vitamin D Insufficiency and Associated Factors Among Canadian Cree: A Cross-sectional Study

Objectives: The purpose of this study is to assess the Vitamin D deficiency awareness and perceptions between the United Arab Emirates (UAE) population. Methods: A cross-sectional study was done among the population of two emirates at the UAE: Abu Dhabi and Sharjah. Results: Overall, 434 participants completed the survey. Majority of people were aware of phenomenon of Vitamin D deficiency, but only 21.4% of them knew that sunlight is considered the main source of Vitamin D. Moreover, less than half of participants check their Vitamin D blood level regularly and around 55% of them follow-up with their physicians after completing the treatment. High proportion of participant females spend <1 h outdoors (60%) and use sunscreen daily (55%) that cause higher prevalence of Vitamin D deficiency among females than males (83% vs. 42%). Conclusion: This research gives some insights regarding the UAE population’s awareness and perceptions of Vitamin D insufficiency. Decreased awareness of sunlight exposure as a major source of Vitamin D, in addition to lifestyle, contributed to Vitamin D deficiency problem among the UAE population, in general, and in females, in particular.

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Vitamin D insufficiency and hyperparathyroidism, general health and quality of life - a cross sectional study

Endocrine Abstracts ◽

10.1530/endoabs.63.p514 ◽

2019 ◽

Author(s):

Lise Sofie Bislev ◽

Lene Langagergaard Rodbro ◽

Lars Rolighed ◽

Tanja Sikjaer ◽

Lars Rejnmark

Keyword(s):

Quality Of Life ◽

Vitamin D ◽

General Health ◽

Cross Sectional Study ◽

Vitamin D Insufficiency ◽

Sectional Study ◽

Cross Sectional

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Vitamin D and PTH: data from a cross-sectional study in an equatorial population

Endocrine Connections ◽

10.1530/ec-20-0206 ◽

2020 ◽

Vol 9 (7) ◽

pp. 667-675

Author(s):

Natércia Neves Marques de Queiroz ◽

Franciane Trindade Cunha de Melo ◽

Fabrício de Souza Resende ◽

Luísa Corrêa Janaú ◽

Norberto Jorge Kzan de Souza Neto ◽

...

Keyword(s):

Vitamin D ◽

Vitamin D Deficiency ◽

Hypovitaminosis D ◽

Serum Levels ◽

Cross Sectional Study ◽

Vitamin D Insufficiency ◽

Institute Of Medicine ◽

Sectional Study ◽

Cross Sectional ◽

Endocrine Society

Objective: Investigate the prevalence of vitamin D deficiency in an equatorial population through a large-sample study. Methods: Cross-sectional study with 30,224 healthy individuals from the North Region, in Brazil (Amazônia – state of Pará), who had 25-hydroxy-vitamin D (25(OH)D) and intact parathyroid hormone (PTH) serum levels measured by immunoassay method. Those with history of acute or chronic diseases were excluded. Abnormal levels of calcium, creatinine, glycemia and albumin were also exclusion criteria. Results: 25(OH)D levels were 29.1 ± 8.2 ng/mL and values <12.7 ng/mL were equal to < −2 s.d. below average. Hypovitaminosis D was present in 10% of subjects according to the Institute of Medicine (values <20 ng/mL) and in 59%, in consonance with Endocrine Society (values 20–30 ng/mL as insufficiency and <20 ng/mL as deficiency) criteria. Individuals were divided according to four age brackets: children, adolescents, adults and elderly, and their 25(OH)D levels were: 33 ± 9; 28.5 ± 7.4; 28.3 ± 7.7; 29.3 ± 8.5 ng/mL, respectively. All groups differed in 25(OH)D, except adolescents vs adults. Regression model showed BMI, sex, living zone (urban or rural) and age as independent variables to 25(OH)D levels. Comparing subjects with vitamin D deficiency (<20 ng/mL) to those with vitamin D insufficiency (20–30 ng/mL), a difference between PTH levels in these two groups was observed (95.9 ± 24.7 pg/mL vs 44.2 ± 64.5 pg/mL; P < 0.01). Additionally, the most accurate predictive vitamin D level for subclinical hyperparathyroidism in ROC curve was 26 ng/mL. Conclusion: Our equatorial population showed low prevalence of vitamin D hypovitaminosis ranging with age bracket. The insufficient category by Endocrine Society was corroborated by our PTH data.

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Vitamin D insufficiency in COVID-19 and influenza A, and critical illness survivors: a cross-sectional study

BMJ Open ◽

10.1136/bmjopen-2021-055435 ◽

2021 ◽

Vol 11 (10) ◽

pp. e055435

Author(s):

Emma A Hurst ◽

Richard J Mellanby ◽

Ian Handel ◽

David M Griffith ◽

Adriano G Rossi ◽

...

Keyword(s):

Vitamin D ◽

Critical Illness ◽

Bone Health ◽

Influenza A ◽

Cross Sectional Study ◽

Vitamin D Insufficiency ◽

Emerging Infections ◽

Sectional Study ◽

Cross Sectional ◽

Hospitalised Patients

ObjectivesThe steroid hormone vitamin D has roles in immunomodulation and bone health. Insufficiency is associated with susceptibility to respiratory infections. We report 25-hydroxy vitamin D (25(OH)D) measurements in hospitalised people with COVID-19 and influenza A and in survivors of critical illness to test the hypotheses that vitamin D insufficiency scales with illness severity and persists in survivors.DesignCross-sectional study.Setting and participantsPlasma was obtained from 295 hospitalised people with COVID-19 (International Severe Acute Respiratory and emerging Infections Consortium (ISARIC)/WHO Clinical Characterization Protocol for Severe Emerging Infections UK study), 93 with influenza A (Mechanisms of Severe Acute Influenza Consortium (MOSAIC) study, during the 2009–2010 H1N1 pandemic) and 139 survivors of non-selected critical illness (prior to the COVID-19 pandemic). Total 25(OH)D was measured by liquid chromatography-tandem mass spectrometry. Free 25(OH)D was measured by ELISA in COVID-19 samples.Outcome measuresReceipt of invasive mechanical ventilation (IMV) and in-hospital mortality.ResultsVitamin D insufficiency (total 25(OH)D 25–50 nmol/L) and deficiency (<25 nmol/L) were prevalent in COVID-19 (29.3% and 44.4%, respectively), influenza A (47.3% and 37.6%) and critical illness survivors (30.2% and 56.8%). In COVID-19 and influenza A, total 25(OH)D measured early in illness was lower in patients who received IMV (19.6 vs 31.9 nmol/L (p<0.0001) and 22.9 vs 31.1 nmol/L (p=0.0009), respectively). In COVID-19, biologically active free 25(OH)D correlated with total 25(OH)D and was lower in patients who received IMV, but was not associated with selected circulating inflammatory mediators.ConclusionsVitamin D deficiency/insufficiency was present in majority of hospitalised patients with COVID-19 or influenza A and correlated with severity and persisted in critical illness survivors at concentrations expected to disrupt bone metabolism. These findings support early supplementation trials to determine if insufficiency is causal in progression to severe disease, and investigation of longer-term bone health outcomes.

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Prevalence of vitamin D insufficiency in school going children of eastern Nepal: a cross-sectional study

International Medicine ◽

10.5455/im.89959 ◽

2020 ◽

Vol 2 (4) ◽

pp. 214

Author(s):

Seraj Khan ◽

Bishnu Pokharel ◽

Tarakant Bhagat ◽

Bishal Joshi ◽

Suman Sapkota ◽

...

Keyword(s):

Vitamin D ◽

Cross Sectional Study ◽

Vitamin D Insufficiency ◽

Sectional Study ◽

Cross Sectional

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Vitamin D status and associated factors among Portuguese older adults: results from the Nutrition UP 65 cross-sectional study

BMJ Open ◽

10.1136/bmjopen-2017-016123 ◽

2017 ◽

Vol 7 (6) ◽

pp. e016123 ◽

Cited By ~ 10

Author(s):

Alejandro Santos ◽

Teresa F Amaral ◽

Rita S Guerra ◽

Ana S Sousa ◽

Luisa Álvares ◽

...

Keyword(s):

Older Adults ◽

Vitamin D ◽

Associated Factors ◽

Cross Sectional Study ◽

Vitamin D Status ◽

Sectional Study ◽

Cross Sectional

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Prevalence and Risk Factors for Vitamin D Insufficiency among Adults with Epilepsy at University Hospital in Jeddah, Saudi Arabia: A Cross Sectional Study

Asian Journal of Education and Social Studies ◽

10.9734/ajess/2021/v14i130348 ◽

2021 ◽

pp. 49-58

Author(s):

Doaa K. Mohorjy ◽

Iman Kamal Ramadan ◽

Bahaa A. Abalkhail ◽

Khalid M. Jaamal

Keyword(s):

Vitamin D ◽

Antiepileptic Drugs ◽

Multiple Linear Regression Model ◽

Cross Sectional Study ◽

Vitamin D Insufficiency ◽

University Hospital ◽

Sectional Study ◽

Cross Sectional ◽

Epileptic Patients

Background: Vitamin D is essential for bone physical condition, and vitamin D insufficiency may add to further autoimmune diseases, infections or even cancer. Enzyme-inducing antiepileptic drugs have been predominantly linked with osteoporosis hazard proved their impacts on vitamin D. The study aim was to determine the prevalence of vitamin D insufficiency and deficiency and the covariates associated with it among the adult epileptic patients attending King Fahd neurology outpatient clinics. Subjects and Methods: 297 adult epilepsy patients joined this cross-sectional study at King Fahd Hospital in 2017. Vitamin D level was considered as deficiency (<10ng/ml), insufficiency (<30ng/ml), or normal (≥30ng/ml). Antiepileptic drugs were sorted out according to their enzyme inducing criteria. Results: 87.88% adult epileptic patients were between 18 – 50 years of age, more than half were females, married, and with higher degree of education, less than half received monthly income of less than 5,000 SR, nearly two third were either smokers or ex-smokers. Multiple linear regression model for predictors of vitamin D insufficiency and deficiency declared that; enzyme induced antiepileptic drugs, polytherapy, and smoking were significantly correlated with vitamin deficiency and insufficiency (p < 0.05). Conclusion: Vitamin D insufficiency and deficiency is widespread among adult epileptic patients. Screening of vitamin D level should be taken into consideration as part of the regular follow up of epileptic patients.

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Vitamin D Provision in Children with Congenital Epidermolysis Bullosa: Cross-Sectional Study

Вопросы современной педиатрии ◽

10.15690/vsp.v20i5.2315 ◽

2021 ◽

Vol 20 (5) ◽

pp. 407-412

Author(s):

Irina Yu. Pronina ◽

Nikolay N. Murashkin ◽

Svetlana G. Makarova ◽

Elena L. Semikina ◽

Dmitry S. Yasakov ◽

...

Keyword(s):

Vitamin D ◽

Vitamin D Deficiency ◽

Epidermolysis Bullosa ◽

Multivariate Regression ◽

Multivariate Regression Analysis ◽

Cross Sectional Study ◽

Vitamin D Insufficiency ◽

Small Samples ◽

Sectional Study ◽

Cross Sectional

Background. Children with congenital epidermolysis bullosa (CEB) can have vitamin D deficiency due to its malabsorption in intestine and reduced synthesis in skin as these patients have restrictions on staying in the sun. However, the prevalence of vitamin D insufficiency/deficiency among patients with CEB remains not fully studied due to the small samples' sizes in previously studies. Objective. Our aim was to study vitamin D provision in children with CEB. Methods. The study included children aged from 3 to 18 years old with simplex and dystrophic types of CEB hospitalized in our department. The serum level of 25(OH)D was determined via chemiluminescence immunoassay. Vitamin D deficiency was established at 25(OH)D concentration of 20-30 ng/ml, deficiency — < 10-20 ng/ml, deep deficiency — < 10 ng/ml. Results. The study included 129 children with CEB (62 (48%) males, median age 6 (3; 10) years). 101 patients had dystrophic type of disease, 28 — simplex. The median 25(OH)D serum concentration in children with CEB was 21.7 (13.0; 36.6) ng/ml. Vitamin D insufficiency was revealed in 36 (28%) patients, deficiency — in 38 (29%), deep deficiency — in 16 (12%). Independent predictors of 25(OH)D concentration were the type of CEB (concentration was higher in children with simplex type) and age (negative association), but not the patients' gender and the examination season, according to multivariate regression analysis. Conclusion. The study has shown low level of vitamin D provision in children with CEB, whilst 25(OH)D concentration depended on the type of disease and the age of patients.

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