Background and Purpose:
Recurrent ischemic strokes increase the risk of disability
and mortality. The role of conventional risk factors in recurrent strokes may change due to increased
awareness of prevention strategies. The aim of this study was to explore the potential risk
factors besides conventional ones which may help to affect the advances in future preventive concepts
associated with one-year stroke recurrence (OSR).
Methods:
We analyzed 6,632 adult patients with ischemic stroke. Differences in clinical characteristics
between patients with and without OSR were analyzed using multivariate logistic regression
and classification and regression tree (CART) analyses.
Results:
Among the study population, 525 patients (7.9%) had OSR. Multivariate logistic regression
analysis revealed that male sex (OR 1.243, 95% CI 1.025 – 1.506), age (OR 1.015, 95% CI
1.007 - 1.023), and a prior history of ischemic stroke (OR 1.331, 95% CI 1.096 – 1.615) were major
factors associated with OSR. CART analysis further identified age and a prior history of ischemic
stroke were important factors for OSR when classified the patients into three subgroups
(with risks of OSR of 8.8%, 3.8%, and 12.5% for patients aged > 57.5 years, ≤ 57.5 years/with no
prior history of ischemic stroke, and ≤ 57.5 years/with a prior history of ischemic stroke, respectively).
Conclusions:
Male sex, age, and a prior history of ischemic stroke could increase the risk of OSR
by multivariate logistic regression analysis, and CART analysis further demonstrated that patients
with a younger age (≤ 57.5 years) and a prior history of ischemic stroke had the highest risk of
OSR.
Esophageal Carcinoma in a Pregnant Woman Who Has Prior History of Gastric Cancer
