Enhanced Electrochemical Determination Of Riboflavin In Biological And Pharmaceutical Samples At Poly (Arginine) Modified Carbon Paste Electrode

An electrogenerated Polyarginine modified carbon paste electrode (PAMCPE) was fabricated through a simple electropolymerization procedure. The devised electrode was characterized by cyclic voltammetry (CV) and Field Emission Scanning Electron Microscopy (FESEM). This electrode was utilized for electrocatalytic estimation of Riboflavin (RF) and its instantaneous resolution with ascorbic acid (AA) and folic acid (FA) in phosphate buffer solution (PBS) of pH 6.0 by differential pulse voltammetry (DPV). It was observed to be a very responsive electrode for the electrochemical detection and quantification of RF. It was revealed that PAMCPE generates higher current response towards RF contrast to the bare carbon paste electrode (BCPE). Under optimized condition, the RF oxidation current values were linearly reliant on the RF concentration increment with a limit of detection (LOD) of 9.3·10-8 M using DPV. The stable PAMCPE was effectively applied for estimation of RF in B-complex pill and complex human blood serum samples.

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Electro-Polymerized Titan Yellow Modified Carbon Paste Electrode for the Analysis of Curcumin

Surfaces ◽

10.3390/surfaces4030017 ◽

2021 ◽

Vol 4 (3) ◽

pp. 191-204

Author(s):

Edwin S. D’Souza ◽

Jamballi G. Manjunatha ◽

Chenthattil Raril ◽

Girish Tigari ◽

Huligerepura J. Arpitha ◽

...

Keyword(s):

Carbon Paste Electrode ◽

Limit Of Detection ◽

Phosphate Buffer Solution ◽

Modified Carbon Paste Electrode ◽

Carbon Paste ◽

Buffer Solution ◽

Solution Ph ◽

Real Sample Analysis ◽

Titan Yellow ◽

Paste Electrode

A modest, efficient, and sensitive chemically modified electrode was fabricated for sensing curcumin (CRC) through an electrochemically polymerized titan yellow (TY) modified carbon paste electrode (PTYMCPE) in phosphate buffer solution (pH 7.0). Cyclic voltammetry (CV) linear sweep voltammetry (LSV) and differential pulse voltammetry (DPV) approaches were used for CRC detection. PTYMCPE interaction with CRC suggests that the electrode exhibits admirable electrochemical response as compared to bare carbon paste electrode (BCPE). Under the optimized circumstances, a linear response of the electrode was observed for CRC in the concentration range 2 × 10−6 M to 10 × 10−6 M with a limit of detection (LOD) of 10.94 × 10−7 M. Moreover, the effort explains that the PTYMCPE electrode has a hopeful approach for the electrochemical resolution of biologically significant compounds. Additionally, the proposed electrode has demonstrated many advantages such as easy preparation, elevated sensitivity, stability, and enhanced catalytic activity, and can be successfully applied in real sample analysis.

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Electrochemical Investigation of Catechol at Poly(niacinamide) Modified Carbon Paste Electrode: A Voltammetric Study

Advances in Physical Chemistry ◽

10.1155/2016/8092860 ◽

2016 ◽

Vol 2016 ◽

pp. 1-8 ◽

Cited By ~ 4

Author(s):

A. B. Teradale ◽

S. D. Lamani ◽

B. E. Kumara Swamy ◽

P. S. Ganesh ◽

S. N. Das

Keyword(s):

Carbon Paste Electrode ◽

Limit Of Detection ◽

Phosphate Buffer Solution ◽

Modified Carbon Paste Electrode ◽

Rate Variation ◽

Carbon Paste ◽

Buffer Solution ◽

Limit Of Quantification ◽

Paste Electrode

A polymeric thin film modified electrode, that is, poly(niacinamide) modified carbon paste electrode (MCPE), was developed for the electrochemical determination of catechol (CC) by using cyclic voltammetric technique. Compared to bare carbon paste electrode (BCPE), the poly(niacinamide) MCPE shows good electrocatalytic activity towards the oxidation of catechol in phosphate buffer solution (PBS) of physiological pH 7.4. All experimental parameters were optimized. Poly(niacinamide) modified carbon paste electrode gave a linear response between concentration of CC and its anodic peak current in the range within 20.6–229.0 μM. The limit of detection (3S/M) and limit of quantification (10S/M) were 1.497 μM and 4.99 μM, respectively. From the study of scan rate variation, the electrode process was found to be adsorption-controlled. The involvement of protons and electrons in the oxidation of CC was found to be equal. The probable electropolymerisation mechanism of niacinamide was proposed. Finally, this method can be used in development of a sensor for sensitive determination of CC.

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Electrochemical Behaviour of Tinidazole at 1,4-Benzoquinone Modified Carbon Paste Electrode and Its Direct Determination in Pharmaceutical Tablets and Urine by Differential Pulse Voltammetry

Journal of Analytical Methods in Chemistry ◽

10.1155/2017/8518707 ◽

2017 ◽

Vol 2017 ◽

pp. 1-10 ◽

Cited By ~ 1

Author(s):

Yosef Nikodimos ◽

Beyene Hagos

Keyword(s):

Carbon Paste Electrode ◽

Limit Of Detection ◽

Direct Determination ◽

Differential Pulse ◽

Modified Carbon Paste Electrode ◽

Reduction Peak ◽

Current Response ◽

Carbon Paste ◽

Paste Electrode

A simple and highly sensitive electrochemical method based on a 1,4-benzoquinone modified carbon paste electrode (1,4-BQMCPE) was described for the determination of tinidazole (TDZ). In Britton Robinson buffer solution, TDZ yields well-defined irreversible reduction peak at −0.344 V on a 1,4-BQMCPE. Compared with that on a bare CPE, the reduction peak of TDZ increased significantly on the modified CPE and the effects of different parameters on the voltammetric responses were also investigated. Differential pulse voltammetric method was proposed and optimized for TDZ determination and its reductive peak current response at 1,4-BQMCPE was found to show linear dependence on the concentration of TDZ in the range of 1.0 × 10−6 to 5.0 × 10−4 M with a linear regression equation, correlation coefficient, limit of detection (LOD), and limit of quantification (LOQ) of IPC (μA) = 0.19958 + 0.02657C (μM), 0.99486, 1.10 × 10−7 M, and 3.77 × 10−7, respectively. Excellent recovery results for spiked TDZ in pharmaceutical tablet samples ranging within 97.44–97.51% and in urine ranging within 95.37–96.91% were observed. The selectivity of the method for TDZ was further studied in the presence of selected potential interferents and confirmed the potential applicability of the developed method for the determination of TDZ.

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Electrocatalytic performance of a zinc sulphide nanoparticles-modified carbon paste electrode for the simultaneous determination of acetaminophen, guanine and adenine

Analytical Methods ◽

10.1039/c8ay00007g ◽

2018 ◽

Vol 10 (11) ◽

pp. 1362-1371 ◽

Cited By ~ 13

Author(s):

Mallappa Mahanthappa ◽

Nagaraju Kottam ◽

Shivaraj Yellappa

Keyword(s):

Carbon Paste Electrode ◽

Phosphate Buffer ◽

Phosphate Buffer Solution ◽

Zinc Sulphide ◽

Modified Carbon Paste Electrode ◽

Carbon Paste ◽

Buffer Solution ◽

Guanine And Adenine ◽

Paste Electrode

The simultaneous electroanalysis of acetaminophen (AC), guanine (G) and adenine (A) was successfully achieved on the zinc sulphide nanoparticles-modified carbon paste electrode (ZnS NPs/CPE) in phosphate buffer solution (PBS).

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Online Coupling of Lab-on-Valve Format to Amperometry Based on Polyvinylpyrrolidone-Doped Carbon Paste Electrode and Its Application to the Analysis of Morin

Journal of Analytical Methods in Chemistry ◽

10.1155/2012/257109 ◽

2012 ◽

Vol 2012 ◽

pp. 1-8 ◽

Cited By ~ 2

Author(s):

Yang Wang ◽

Guojun Yao ◽

Jie Tang ◽

Chun Yang ◽

Qin Xu ◽

...

Keyword(s):

Carbon Paste Electrode ◽

Supporting Electrolyte ◽

Phosphate Buffer Solution ◽

Current Response ◽

Oxidation Peak ◽

Carbon Paste ◽

Buffer Solution ◽

Electrochemical Behaviors ◽

Paste Electrode

The potential capabilities and analytical performance of lab-on-valve (LOV) manifold as a front end to amperometry have been explored for the on-line determination of morin. Meanwhile, the electrochemical behaviors of morin were investigated based on polyvinylpyrrolidone- (PVP-) doped carbon paste electrode (CPE), which found that PVP can significantly improve its oxidation peak current. The excellent amperometric current response was achieved when the potential difference (ΔE) of 0.6 V was implemented in pH 6.5 phosphate buffer solution (PBS) that served as the supporting electrolyte. A well-defined oxidation peak has been obtained in studies using PVP as a modifier of CPE based on the oxidation of morin. The present work introduces the LOV technique as a useful tool for amperometric measurement, documents advantages of using programmable flow, and outlines means for miniaturization of assays on the basis of PVP modified CPE. The proposed method was applied successfully to the determination of morin in real samples, and the spiked recoveries were satisfactory.

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Voltammetric study of secnidazole and its determination in pharmaceutical tablet using 1, 4-benzoquinone modified carbon paste electrode

10.31221/osf.io/72azx ◽

2019 ◽

Author(s):

Chem Int

Keyword(s):

Carbon Paste Electrode ◽

Limit Of Detection ◽

Modified Carbon Paste Electrode ◽

Carbon Paste ◽

Buffer Solution ◽

Limit Of Quantification ◽

Pharmaceutical Tablet ◽

Relative Standard ◽

Paste Electrode

In this study voltammetric behaviour of secnidazole (SCZ) at 1, 4-Benzoquinone Modified Carbon Paste Electrode (1,4-BQMCPE) was investigated in Britton Robinson buffer solution using cyclic voltammetric technique. A well-defined cathodic peak was observed for the SCZ in the entire pH range. The current increases steadily with scan rate and the results indicated that the process is irreversible reduction and adsorption controlled. The number of electrons transferred and different kinetic parameters like transfer coefficient and rate constant were calculated by using cyclic voltammetry technique. Differential pulse voltammetric method has been used for the determination of SCZ content in pharmaceutical tablet. This method enabled to determine SCZ in the concentration range 1.0 × 10-8 to 4.0 × 10-4 M. The limit of detection (LOD) and limit of quantification (LOQ) were found to be 2.13 × 10-9 and 2.85 × 10-9 respectively. The method was applied to determine the content of SCZ in different sample solutions of SCZ tablet with excellent recovery and relative standard deviation results (99.892±1.53 respectively) for spiked standard SCZ in tablet sample solutions. The selectivity of the method for SCZ was further studied in the presence of selected potential interferents such as fluconazole, azithromycin etc and confirmed the potential applicability of the developed method for the determination of SCZ in real pharmaceutical tablets.

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Differential Pulse Adsorptive Stripping Voltammetric Determination of Nifedipine and Nimodipine in Pharmaceutical Formulations, Urine, and Serum Samples by Using a Clay‐Modified Carbon‐Paste Electrode

Analytical Letters ◽

10.1081/al-200026681 ◽

2004 ◽

Vol 37 (10) ◽

pp. 2079-2098 ◽

Cited By ~ 22

Author(s):

T. Madhusudana Reddy ◽

S. Jayarama Reddy

Keyword(s):

Carbon Paste Electrode ◽

Pharmaceutical Formulations ◽

Differential Pulse ◽

Voltammetric Determination ◽

Modified Carbon Paste Electrode ◽

Carbon Paste ◽

Serum Samples ◽

Urine And Serum ◽

Paste Electrode

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Direct Electron Transfer of Cytochrome c on ZnO Nanoparticles Modified Carbon Paste Electrode

ISRN Biophysics ◽

10.5402/2012/937265 ◽

2012 ◽

Vol 2012 ◽

pp. 1-6 ◽

Cited By ~ 6

Author(s):

Masoud Negahdary ◽

Saeed Rezaei-Zarchi ◽

Neda Rousta ◽

Soheila Samei Pour

Keyword(s):

Cytochrome C ◽

Carbon Paste Electrode ◽

Zno Nanoparticles ◽

Direct Electron Transfer ◽

Direct Electrochemistry ◽

Phosphate Buffer Solution ◽

Modified Carbon Paste Electrode ◽

Carbon Paste ◽

Buffer Solution ◽

Paste Electrode

The direct electrochemistry of cytochrome c (cyt c) immobilized on a modified carbon paste electrode (CPE) was described. The electrode was modified with ZnO nanoparticles. Direct electrochemistry of cytochrome c in this paste electrode was easily achieved, and a pair of well-defined quasireversible redox peaks of a heme Fe (III)/Fe(II) couple appeared with a formal potential (E0) of −0.303 V (versus SCE) in pH 7.0 phosphate buffer solution (PBS). The fabricated modified bioelectrode showed good electrocatalytic ability for reduction of H2O2. The preparation process of the proposed biosensor was convenient, and the resulting biosensor showed high sensitivity, low detection limit, and good stability.

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MODIFICATION OF CARBON PASTE ELECTRODE WITH CROWN ETHER (DIBENZO-18-CROWN-6) FOR ASCORBIC ACID ANALYSIS USING DIFFERENTIAL PULSE VOLTAMMETRY METHOD

ALCHEMY Jurnal Penelitian Kimia ◽

10.20961/alchemy.11.2.728.175-191 ◽

2016 ◽

Vol 11 (2) ◽

pp. 175

Author(s):

Irdhawati Irdhawati ◽

Manuntun Manurung ◽

Anisha Maulinasari

Keyword(s):

Ascorbic Acid ◽

Crown Ether ◽

Carbon Paste Electrode ◽

Limit Of Detection ◽

Differential Pulse ◽

Modified Carbon Paste Electrode ◽

Range Limit ◽

Carbon Paste ◽

Paste Electrode

In this research, the modified carbon paste electrode with crown ether (dibenzo-18-crown-6) has been prepared, for determination of ascorbic acid. Some of parameters observed were optimization of crown ether composition in carbon paste, pH of solution, linear concentration range, limit of detection, reproducibility, and recovery. The optimum performance of the prepared electrode was applied for determination of commercialsampleswhich contain of ascorbic acid. The result of this research showsthat the optimum composition of crown ether in carbon paste is 0.6 % at pH 4. Linear range of concentration obtained is from 2 - 200 μM. The detection limit and percentage of recovery are 1.243 μM and 101.31 %, respectively. The modified electrode has HorRat value less than 2, it indicates a good reproducibility. Analysis of 4 commercial samples which contain of ascorbic acid were in agreement with the content listed in the label with the suitability of 94 - 100 %.

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