Neurophysiological features in patients with migraine at risk for epilepsy

Objective: to study the electrophysiological parameters of brain bioelectric activity and features of the autonomous nervous system assessing heart rate variability, sympathetic skin response, clinical and physiological tests depending on the lateralization of migraine pain syndrome in the right or left brain hemisphere in patients with epileptic electroencephalogram (EEG) signs and migraine.Material and methods. Thirty six patients with aura-free episodic migraine at risk of developing epilepsy and 9 age-matched healthy subjects were examined. All participants underwent EEG, clinical and physiological tests, assessment of heart rate variability and sympathetic skin response.Results. Patients with right-hemisphere migraine headache had signs of activated sympathetic nervous system at baseline level and during exercise, lower baseline EEG epileptiform activity and in provocative tests. In contrast to the subjects of this group, patients of other group featured with a more stable migraine pain syndrome in the left hemisphere tended to dominate with functional activity of the parasympathetic system such as increased trophotropic support during exercise, as well as greater magnitude of baseline epileptiform bioelectric activity and during load tests.Conclusion. Values of heart rate variability in combination with objective results of clinical and physiological assessment of the autonomous nervous system and electrophysiological parameters of brain bioelectric activity are reliable prognostic indicators for varying functional conditions in patients with episodic migraine.

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Autonomic Nervous System Dysfunction in Stroke Patients: Clinical Asessment by Sympathetic Skin Response(SSR) and Heart Rate Variability.

The Japanese Journal of Rehabilitation Medicine ◽

10.2490/jjrm1963.36.658 ◽

1999 ◽

Vol 36 (10) ◽

pp. 658-668 ◽

Cited By ~ 1

Author(s):

Tetsuo IKAI ◽

Satoshi MIYANO

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Nervous System ◽

Autonomic Nervous System ◽

Sympathetic Skin Response ◽

Stroke Patients ◽

Autonomic Nervous System Dysfunction ◽

Autonomic Nervous ◽

Skin Response

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Noninvasive measurements to evaluate the effects of military training on the human autonomic nervous system

Asian Biomedicine ◽

10.5372/1905-7415.0804.314 ◽

2014 ◽

Vol 8 (4) ◽

pp. 453-461 ◽

Cited By ~ 1

Author(s):

Ji-Hong Chen ◽

Qian Zhang ◽

Xin Liu ◽

Zhixin Li ◽

Cuizhen Zhang ◽

...

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Nervous System ◽

Autonomic Nervous System ◽

Military Training ◽

Low Frequency ◽

Sympathetic Skin Response ◽

Pacemaker Activity ◽

Autonomic Nervous ◽

Skin Response

AbstractBackground: Chinese university freshmen receive 4-weeks military training that involved moderate to intense physical exercise. Studies have demonstrated heterogeneous effects of exercise on the autonomic nervous system.Objective: To evaluate the effects of training on the autonomic nervous system noninvasively using electrogastrograms, heart rate variability (HRV), pulse rate, and the sympathetic skin response (SSR).Methods: Twenty freshmen received all assessments in the fasting state and after a standard meal: (1) one week before the training, (2) at the end of the second week of the training, and (3) one week after the training.Results: (1) The training had a significant effect on meal-induced gastric pacemaker activity. Before the training, a standard meal did not increase the dominant frequency of gastric slow waves, but the frequency increased during and after the training; (2) The preprandial high frequency (HF), low frequency (LF), and very low frequency (VLF) components of heart rate variability decreased significantly after the training. The ratio of the LF and HF (LF/HF) of the heart rate variability (HRV) did not significantly change after a meal or training condition. The basal pulse rate did not change. The latencies of the sympathetic skin response (SSR), as measured in the arm muscle, increased in response to the training.Conclusion: Military training affects meal-induced changes in gastric pacemaker activity, causes a marked reduction of the vagal tone to the heart with maintenance of the vagal-sympathetic balance, and its effects on SSR may reflect a reduction in sympathetic tone.

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Wavelet transform to quantify heart rate variability and to assess its instantaneous changes

Journal of Applied Physiology ◽

10.1152/jappl.1999.86.3.1081 ◽

1999 ◽

Vol 86 (3) ◽

pp. 1081-1091 ◽

Cited By ~ 145

Author(s):

Vincent Pichot ◽

Jean-Michel Gaspoz ◽

Serge Molliex ◽

Anestis Antoniadis ◽

Thierry Busso ◽

...

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Nervous System ◽

Fourier Transform ◽

Wavelet Transform ◽

Wavelet Transforms ◽

Autonomous Nervous System ◽

Dynamic Changes ◽

Nonstationary Signals ◽

Higher Doses

Heart rate variability is a recognized parameter for assessing autonomous nervous system activity. Fourier transform, the most commonly used method to analyze variability, does not offer an easy assessment of its dynamics because of limitations inherent in its stationary hypothesis. Conversely, wavelet transform allows analysis of nonstationary signals. We compared the respective yields of Fourier and wavelet transforms in analyzing heart rate variability during dynamic changes in autonomous nervous system balance induced by atropine and propranolol. Fourier and wavelet transforms were applied to sequences of heart rate intervals in six subjects receiving increasing doses of atropine and propranolol. At the lowest doses of atropine administered, heart rate variability increased, followed by a progressive decrease with higher doses. With the first dose of propranolol, there was a significant increase in heart rate variability, which progressively disappeared after the last dose. Wavelet transform gave significantly better quantitative analysis of heart rate variability than did Fourier transform during autonomous nervous system adaptations induced by both agents and provided novel temporally localized information.

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Sympathetic Skin Response and Heart Rate Variability in Patients With Huntington Disease

Archives of Neurology ◽

10.1001/archneur.56.10.1248 ◽

1999 ◽

Vol 56 (10) ◽

pp. 1248 ◽

Cited By ~ 35

Author(s):

Khema R. Sharma ◽

Jose G. Romano ◽

D. Ram Ayyar ◽

Francisco T. Rotta ◽

Alicia Facca ◽

...

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Huntington Disease ◽

Sympathetic Skin Response ◽

Skin Response

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Heart Rate Variability and Sympathetic Skin Response in Male Patients Suffering From Acute Alcohol Withdrawal Syndrome

Alcoholism Clinical and Experimental Research ◽

10.1111/j.1530-0277.2006.00191.x ◽

2006 ◽

Vol 30 (9) ◽

pp. 1592-1598 ◽

Cited By ~ 23

Author(s):

Karl-Jurgen Bar ◽

Michael Karl Boettger ◽

Rene Neubauer ◽

Marei Groteluschen ◽

Thomas Jochum ◽

...

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Alcohol Withdrawal ◽

Withdrawal Syndrome ◽

Sympathetic Skin Response ◽

Alcohol Withdrawal Syndrome ◽

Skin Response ◽

Male Patients

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Evaluation of Autonomic Nervous System in Children With Cerebral Palsy: Clinical and Electophysiological Study

10.21203/rs.3.rs-290905/v1 ◽

2021 ◽

Author(s):

Hanan Galal Azouz ◽

Ali M Abdel Mohsen ◽

Rana M Mohamed ◽

hayam mostafa abdelghany

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Cerebral Palsy ◽

Autonomic Dysfunction ◽

Sympathetic Skin Response ◽

Spastic Cerebral Palsy ◽

Control Group ◽

Healthy Children ◽

Children With Cerebral Palsy ◽

Skin Response

Abstract Cerebral palsy (CP) is the most prevalent severe motor disability among children. The aim of this work was to assess autonomic dysfunction in children with cerebral palsy clinically and electrophysiologically .The study was carried out on forty children with cerebral palsy their age ranged from 4-12 years and twenty healthy children with matched age and sex as control group. CP children were subjected to questionnaire for autonomic dysfunction symptoms. Both CP children and Control group were assessed for Sympathetic Skin Response and Heart rate variability. Most of children had quadriplegic spastic cerebral palsy (82.5%). Based on Gross motor function classification system (GMFCS) classification the majority of children were in levels 4 and 5. The prevalence of autonomic dysfunction symptoms was 80% for thermoregulatory abnormalities (cold extremities), chronic constipation 65%, sleep disturbance 52.5%, loss of appetite 47.5%, sweating abnormalities 40% , recurrent nausea and/or vomiting 25%, increased sensitivity to light or dark 22.5% and bloating 15%. The percentage of unelicited Sympathetic skin response in CP children was 47.5% and 60% in upper limbs and lower limbs respectively, all of them were in level 4 and 5 of GMFCS. 20% of CP children had postural hypotension. Mean Heart rate of CP children was significantly increased more than healthy children upon head tilt test. Sympathetic Skin Response and Heart rate variability were proven to be simple and non invasive procedures in investigating autonomic dysfunction in CP children.

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Immediate Effect of Primal Reflex Release Technique on Heart Rate Variability in Chronic Neck Pain: A Case Report

International Journal of Health Sciences and Research ◽

10.52403/ijhsr.20210624 ◽

2021 ◽

Vol 11 (6) ◽

pp. 157-160

Author(s):

Mayura P. Deshmukh ◽

Ashwini N. Patil ◽

Gaurang Baxi

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Nervous System ◽

Neck Pain ◽

Chronic Neck Pain ◽

Startle Reflex ◽

Autonomous Nervous System ◽

Large Sample Size ◽

Release Technique ◽

The One

Primal reflex release technique (PRRT) is a paradigm shift in the treatment of pain which follows the principle of rebooting the autonomous nervous system (ANS), by down regulating the upgraded sympathetic component of ANS in a variety of pain syndromes. To check the effect of PRRT on chronic neck pain, a case study was done using Heart Rate Variability (HRV) and Visual Analogue Scale (VAS) as outcome measures. After conducting the one minute nociceptive exam for startle reflex, indication of the upgraded Sympathetic Nervous System (SNS), a single session of PRRT was carried out on a 24 year old female patient with chronic neck pain having a VAS score of 7 on activity and that of 5 on rest. Pre and post treatment HRV analysis was done using frequency domain and time domain parameters. Post PRRT treatment, an improvement in VAS scale with a score of 4 on activity and that of 3 on rest was seen. HRV showed a decrease in HFnu (26.7 vs 24.5), RMSSD (63.553 vs 59.216), SDNN (28.58 vs 34.82) and PNN50 (48.3 vs 42.5) which refers to decreased parasympathetic activity, and increased LFnu (73.3 vs 75.5) which indicates increased sympathetic activity. This was the first study evaluating the effect of PRRT with HRV. Further research needs to be conducted to validate HRV findings in chronic pain patients undergoing PRRT using a large sample size and interval based assessment of HRV. Key words: Neck Pain, Primal reflex release technique, Startle Reflex, Heart Rate Variability.

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Characterization of Heart Rate Variability Changes Following Asphyxia in Rats

Methods of Information in Medicine ◽

10.1055/s-0038-1633847 ◽

2004 ◽

Vol 43 (01) ◽

pp. 118-121 ◽

Cited By ~ 7

Author(s):

L. Moraru ◽

L. Cimponeriu ◽

S. Tong ◽

N. Thakor ◽

A. Bezerianos

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Nervous System ◽

Cardiac Arrest ◽

Frequency Domain ◽

Linear Time ◽

Approximate Entropy ◽

Recovery Process ◽

Autonomous Nervous System ◽

Nonlinear Parameters

Summary Objectives: A non-invasive method to monitor the functioning of the autonomous nervous system consists in heart rate variability (HRV) analysis. The aim of this study was to investigate the changes on HRV after an asphyxia experiment in rats, using several linear (time and frequency domain) and nonlinear parameters (approximate entropy, SD1 and SD2 indices derived from Poincare plots). Methods: The experiments involved the study of HRV changes after cardiac arrest (CA) resulting from 5 min of hypoxia and asphyxia, followed by manual resuscitation and return of spontaneous circulation. 5 min stationary periods of RR intervals were selected for further analysis from 5 rats in following distinct situations: 1) baseline, 2) 30 min after CA, 3) 60 min after CA, 4) 90 min after CA, 5) 120 min after CA, 6) 150 min after CA. The ANS contribution has been delineated based on time and frequency domain analysis. Results and Conclusions: The results indicate that the recovery process following the asphyxia cardiac arrest reflects the impaired functioning of the autonomic nervous system. Both linear and nonlinear parameters track the different phases of the experiment, with an increased sensitivity displayed by the approximate entropy (ApEn). After 150 min the ApEn RRI parameter recovers to its baseline value. The results forward the ApEn as a more sensitive parameter of the recovery process following the asphyxia.

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