scholarly journals A case of bladder purpura

2021 ◽  
Vol 17 (2) ◽  
pp. 208-211
Author(s):  
P. P. Denine
Keyword(s):  
Mucous Membrane ◽  
Normal Mucous Membrane ◽  
Surgical Clinic

In March 1921, a sick peasant woman was admitted to the Hospital Surgical Clinic with complaints of hematuria, which appeared 3-4 days after a slight malaise. The rest of the patient felt healthy. Objectively, the patient did not represent any deviation from the norm. In particular, her t is normal, there are no symptoms of scurvy. For hematuria, cystoscopic examination. Cystoscopy revealed: the orifices of the ureters are normal, on the normal mucous membrane there are scattered red spots the size of a pinhead and larger, very similar to flea bites; these specks are scattered in various parts of the bladder, mainly at the bottom of it; there are no infiltrates around the spots and other changes.

scholarly journals Electron Microscopic Observation of Human Normal Mucous Membrane of Maxillary Sinus

1978 ◽  
Vol 71 (5special2) ◽  
pp. 681-690
Author(s):  
Yukikazu Hyo ◽  
Tsutomu Hoshiya ◽  
Yasuteru Yamanaka ◽  
Shun-ichi Sakai ◽  
Kuniyuki Yamamoto
Keyword(s):  
Maxillary Sinus ◽  
Mucous Membrane ◽  
Microscopic Observation ◽  
Electron Microscopic Observation ◽  
Electron Microscopic ◽  
Normal Mucous Membrane

scholarly journals CHARACTERISTICS OF THE IMMUNE MICROENVIRONMENT OF THE NORMAL MUCOUS MEMBRANE OF THE PERITUMORAL AREA IS AN ADDITIONAL INDEPENDENT PROGNOSTIC FACTOR IN GASTRIC CANCER

2021 ◽  
Vol 20 (1) ◽  
pp. 74-86
Author(s):  
N. V. Danilova ◽  
V. M. Kkomyakov ◽  
A. V. Chayka ◽  
I. A. Mikhailov ◽  
N. A. Oleynikova ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Prognostic Factor ◽  
Mucous Membrane ◽  
Patient Survival ◽  
Lymphocyte Infiltration ◽  
Immune Microenvironment ◽  
Average Area ◽  
Negative Prognostic Factor ◽  
Normal Mucous Membrane ◽  
Analysis System

The aim of the study was to study and evaluate the predictive value of the immune microenvironment of gastric cancer and morphologically normal mucous membrane of the peritumoral area using an automatic morphometric analysis system on the example of CD 8+ cells.Material and Methods. Surgical samples from 130 patients with a verified diagnosis of gastric cancer were used. After immunohistochemical staining with antibodies to CD 8, a morphological assessment was performed according to the original method. We assessed the average area of CD 8+ cells in three fields of view (lens magn. ×20) using the automatic system of morphometric analysis LAS X (Leica) in the central part of the tumor and areas of morphologically normal mucous membrane of the peritumoral region directly adjacent to the tumor tissue. The results were compared with the main clinical and morphological characteristics of the tumor as well as with the overall five-year survival of patients.Results and Discussion. A high density of CD 8+ infiltration of normal mucous membrane of the peritumoral area was observed in groups T4a and T4b by the depth of invasion (n=96, p=0.0089) and was associated with the presence of emboli in the lymphatic vessels (n=96, p=0.0102) and with the more advanced stage of gastric cancer (n=96, p=0.0107). The studied cases were divided into two groups: less than 3300 square micrometers (better patient survival; n=79, p=0.01) and more than 3300 square micrometers according to the average area of CD 8+ cells in normal mucous membrane of the peritumoral area. According to multivariate survival analysis using the Cox regression model, it was found that the average area of CD 8+ cells in normal mucous membrane of the peritumoral area was a significant negative prognostic factor (RR=1.537; CI : 0.761–3.105; p<0.01) comparable in degree covariance with the stage of the tumor A similar indicator assessed in central part of the tumor was not significantly associated with patient survival (RR=0.803; CI : 0.574–1.122; p>0.05).Conclusion. The possibility of using an automatic analysis system to evaluate the immune microenvironment in gastric cancer was demonstrated for the first time. It was found that a high level of CD 8+ lymphocyte infiltration of morphologically normal mucous membrane of the peritumoral area was an independent negative prognostic factor. Therefore, we recommend the mandatory preoperative biopsy sampling from the mucous membrane of the peritumoral region for morphometric assessment of CD 8+ lymphocyte infiltration. 

scholarly journals Bilateral papillary ovarian cystoma and vaginal cyst

1898 ◽  
Vol 12 (11) ◽  
pp. 1407
Author(s):  
Editorial Board
Keyword(s):  
Mucous Membrane ◽  
Ovarian Cyst ◽  
Vaginal Wall ◽  
Ovarian Cysts ◽  
Medical Review ◽  
Normal Mucous Membrane ◽  
The Right ◽  
Cyst Cavity

Abstracts. Review of Obstetric and Gynecological literature: Russian.Sutkin. Bilateral papillary ovarian cyst and vaginal cyst- ("Medical Review", 1898, August).In a patient with papillary ovarian cysts and vaginal cysts, after removal of the ovarian cysts, the vaginal cyst, the size of a pigeon's egg, was also partially removed, so that the prominent segment of the tumor was captured by the dentate root and scissors of the free stump; a strip of sterilized gauze is inserted into the cyst cavity. When examining the vagina after 3 weeks, on the right side of it, correspondingly to the base of the former cyst, a barely imperceptible ridge is felt, going into the form of a longitudinal ellipsis; the very base of the cyst, which is now part of the vaginal wall, is, when examined, a normal mucous membrane.

Fluorescence Bronchoscopy

1982 ◽  
Vol 91 (1) ◽  
pp. 57-60 ◽  
Author(s):  
Dietrich Hürzeler
Keyword(s):  
Mucous Membrane ◽  
False Negative ◽  
Histological Change ◽  
Ciliary Activity ◽  
Negative Results ◽  
False Negative Results ◽  
Neoplastic Change ◽  
Surface Marking ◽  
Lymphangitis Carcinomatosa ◽  
Normal Mucous Membrane

A new method of fluorescence bronchoscopy is presented which uses a standard light source and a special filter combination to permit the carrying out of fluorescence bronchoscopy with a surface marking method by means of inhaling a fluorescein solution. Normal mucous membrane, or mucous membrane with no histological change other than inflammation, which is cleansed by ciliary activity, does not usually fluoresce for a period longer than about two hours after the inhalation. There were, it is true, 13 false positive fluorescences out of 52 fluorescing areas in the mucous membrane. Correctly recorded were 39 cases of positive, ie, visible tumors, metaplasias, accumulation of mucous glands in the epithelium, and mucous membrane which had undergone a neoplastic change in the sense of a lymphangitis carcinomatosa or a mucous membrane carcinosis; these all caused fluorescence. The false negative results amounted to only two nonfluorescing tumors and one metaplasia. These diagnoses arise from the first 100 patients examined by this method. The fact must be especially emphasized that out of the 58 carcinoma cases, there were 7 where neoplastic changes in the mucous membrane were diagnosed by the fluorescence technique, although they had not been recognized macroscopically either by the naked eye or by the Hopkins optical technique.

Toll-like receptors and the tendency of normal mucous membrane to transform to polyp or colorectal cancer

2009 ◽  
Vol 38 (5) ◽  
pp. 574 ◽  
Author(s):  
I. Niedzielska ◽  
T. Orawczyk ◽  
K. Ziaja ◽  
M. Tkacz ◽  
J. Starzewski ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Mucous Membrane ◽  
Toll Like Receptors ◽  
Normal Mucous Membrane

Pathology of Bone Cells in Pigs with Experimental Turbinate Osteoporosis (Atrophic Rhinitis)

1971 ◽  
Vol 29 ◽  
pp. 304-305
Author(s):  
A. W. Fetter ◽  
C. C. Capen
Keyword(s):  
Mucous Membrane ◽  
Bone Cells ◽  
Atrophic Rhinitis ◽  
Infectious Agents ◽  
Metabolic Disturbances ◽  
Progressive Reduction ◽  
Naturally Occurring ◽  
Fundamental Cause ◽  
Osteocytic Osteolysis ◽  
Uncertain Etiology

Atrophic rhinitis in swine is a disease of uncertain etiology in which infectious agents, hereditary predisposition, and metabolic disturbances have been reported to be of primary etiologic importance. It shares many similarities, both clinically and pathologically, with ozena in man. The disease is characterized by deformity and reduction in volume of the nasal turbinates. The fundamental cause for the localized lesion of bone in the nasal turbinates has not been established. Reduced osteogenesis, increased resorption related to inflammation of the nasal mucous membrane, and excessive resorption due to osteocytic osteolysis stimulated by hyperparathyroidism have been suggested as possible pathogenetic mechanisms.The objectives of this investigation were to evaluate ultrastructurally bone cells in the nasal turbinates of pigs with experimentally induced atrophic rhinitis, and to compare these findings to those in control pigs of the same age and pigs with the naturally occurring disease, in order to define the fundamental lesion responsible for the progressive reduction in volume of the osseous core.

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