scholarly journals Estimation of the risk factors in pregnant women and prediction of congenital fetal anomalies

2018 ◽  
Vol 99 (5) ◽  
pp. 748-753
Author(s):  
F S Dzhamankulova ◽  
M S Musuraliev ◽  
A A Sorokin

Aim. To estimate the value of different maternal risk factors to develop a prognostic model for prevention of fetal congenital anomalies. Methods. A prospective complex clinical and laboratory and functional examination of 629 pregnant women with fetal congenital anomalies and 206 pregnant women without fetal pathology was conducted with a comparative assessment of the medical and social risk factors for congenital defects. To build a predictive model for prevention of congenital anomalies, the logistic regression method was used. Results. According to static analysis, significant medical and social risk factors for congenital anomalies are acute respiratory viral infection with fever in early gestational age (OR=20.0, 95 % CI: 2.756-145.7), the absence of prophylactic folic acid (OR=15.16, 95 % CI: 7.35-31.31), polyhydramnion (OR=14.2, 95 % CI: 4.453-45.18), oligohydramnion (OR=3.258, 95 % CI: 1.382-7.679), preeclampsia (OR=3.51, 95 % CI: 1.11-8.96) and maternal anemia (OR=4.75, 95 % CI: 2.51-8.99). As a result, we received the predictive model with high sensitivity equal to 0.924, specificity 0.655 and Sommers’ D 0.629. Nagelkerke’s R square of the model was 0.552 (moderate). This means that the model explains 55.2 % variation of the dependent variable. Conclusion. The conducted study allowed identifying the predictors affecting the development of congenital fetal anomalies, and the developed predictive model for determining the probability of congenital fetal anomalies in the early antenatal period is characterized by high sensitivity and can be suggested for the use during the monitoring phase of the pregnant woman in the outpatient setting.

PLoS ONE ◽  
2017 ◽  
Vol 12 (8) ◽  
pp. e0182544 ◽  
Author(s):  
Emma Popo ◽  
Sara Kenyon ◽  
Sophie-Anna Dann ◽  
Christine MacArthur ◽  
Jacqueline Blissett

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Hannah Rayment-Jones ◽  
James Harris ◽  
Angela Harden ◽  
Sergio A. Silverio ◽  
Cristina Fernandez Turienzo ◽  
...  

Abstract Background Black and minority ethnic women and those with social risk factors such as deprivation, refugee and asylum seeker status, homelessness, mental health issues and domestic violence are at a disproportionate risk of poor birth outcomes. Language barriers further exacerbate this risk, with women struggling to access, engage with maternity services and communicate concerns to healthcare professionals. To address the language barrier, many UK maternity services offer telephone interpreter services. This study explores whether or not women with social risk factors find these interpreter services acceptable, accessible and safe, and to suggest solutions to address challenges. Methods Realist methodology was used to refine previously constructed programme theories about how women with language barriers access and experience interpreter services during their maternity care. Twenty-one longitudinal interviews were undertaken during pregnancy and the postnatal period with eight non-English speaking women and their family members. Interviews were analysed using thematic framework analysis to confirm, refute or refine the programme theories and identify specific contexts, mechanisms and outcomes relating to interpreter services. Results Women with language barriers described difficulties accessing maternity services, a lack of choice of interpreter, suspicion around the level of confidentiality interpreter services provide, and questioned how well professional interpreters were able to interpret what they were trying to relay to the healthcare professional during appointments. This resulted in many women preferring to use a known and trusted family member or friend to interpret for them where possible. Their insights provide detailed insight into how poor-quality interpreter services impact on their ability to disclose risk factors and communicate concerns effectively with their healthcare providers. A refined programme theory puts forward mechanisms to improve their experiences and safety such as regulated, high-quality interpreter services throughout their maternity care, in which women have choice, trust and confidence. Conclusions The findings of this study contribute to concerns highlighted in previous literature around interpreter services in the wider healthcare arena, particularly around the lack of regulation and access to high-quality interpretation. This is thought to have a significant effect on pregnant women who are living socially complex lives as they are not able to communicate their concerns and access support. This not only impacts on their safety and pregnancy outcomes, but also their wider holistic needs. The refined program theory developed in this study offers insights into the mechanisms of equitable access to appropriate interpreter services for pregnant women with language barriers.


Author(s):  
John F. Steiner ◽  
Glenn K. Goodrich ◽  
Kelly R. Moore ◽  
Spero M. Manson ◽  
Laura M. Gottlieb ◽  
...  

Innova ◽  
2021 ◽  
Vol 22 (1) ◽  
pp. 33-38
Author(s):  
Владимир Игоревич Тимошилов ◽  
◽  
Альберт Генрихович Ластовецкий

Period 2014-2019 characterized by a certain increase in social instability in Russia, which led to an increase of social risk factors for drug addiction. In the Kursk region, at the same time, there have been changes in the regulation of anti-drug prevention, a large number of specialists have been trained, and a movement of competent volunteers has developed. In this regard, the epidemiological data for 2014-2019 are of particular interest. For the period from 2005 to 2019 the primary incidence of alcohol use disorders in Russia decreased from 147.4 to 48.3, in the Kursk region – from 106 to 53.5 cases per 100 000 population per year. Of the adjacent regions in 2019, a lower incidence rate than in the Kursk region was noted only in the Belgorod region – 39.4 cases per 100,000 population. Primary incidence of disorders associated with the use of narcotic active substances, during 2014-2019 in Russia as a whole decreased from 15 to 9.8, in the Kursk region – from 11.3 to 4 new cases per 100 000 inhabitants per year. In 2019, the detection rate of primary incidence of drug addiction and substance abuse was significantly higher than in the Kursk region in Bryansk and Lipetsk. Despite favorable trends, it was noted that the coronavirus pandemic and the restrictions introduced to combat it can have a significant impact on the risk factors for drug addiction, which requires the adaptation of preventive programs to new conditions.


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