scholarly journals Correlation between quality of life indicators, peculiarities of diet and clinical manifestations of multiple sclerosis

2000 ◽  
Vol XXXII (3-4) ◽  
pp. 17-22
Author(s):  
M. Yu. Tatarinova ◽  
N. F. Smirnova ◽  
A. N. Boyko

Multiple sclerosis is one of the most important problems of neurology. Onset age of disease is young, and young people, which are able to work often become invalids. That is why multiple sclerosis is medical and social problem. Questions of epidemiology and quality of life of our patients with multiple sclerosis are modern questions of multiple sclerosis problem. Our scientific work is devoted to relation between indicators of quality of life and dietary factors, clinical peculiarities of disease. We received interesting results. We found, that among males most important for quality of life are physical functions and common condition of health. And emotial problems, reduction of social functions, reduction of vitality are most important for quality of life among females.

2010 ◽  
Vol 9 (4) ◽  
pp. 63-69
Author(s):  
V. N. Karnaukh ◽  
Yu. A. Lugovtsova ◽  
I. A. Barabash

The study explored the life quality of 94 multiple sclerosis patients in comparison to healthy respondents and in dependence to different parameters of the disease with the use of SF-36 questionnaire. The study has discovered a decline of all the factors of life quality and their dependence on disablement intensity, clinical course and duration of the disease. Immunomodulatory therapy contributed to the improvement of life quality factors.


2021 ◽  
Author(s):  
Vladimir V. Belopasov

The article highlights the pathogenesis, clinical manifestations of lesions of the central and peripheral nervous system that have arisen or persist in patients in the postcoid period (Long-COVID-19). Their correct assessment, the use of effective methods of complex treatment, targeted neurorehabilitation contribute to the reversibility of functional disorders, prevention, reduction of disability, improvement of quality of life indicators, prevention of the progression of cognitive, emotional, behavioral disorders initiated by SARS-CoV-2.


Author(s):  
Sadagat Ganbarovna Guseinova ◽  
S. S Imamverdieva ◽  
E. E Mustafaeva ◽  
M. Yu Mamedova ◽  
K. N Yusifova

Clinical-neurophysiological bases of the combined use of Nucleo CMF forte preparation and interference therapy in the complex treatment of patients with vertebrogenic radiculopathies were studied. The beneficial effect of this therapeutic complex on the clinical course of the disease, more pronounced analgesic effect and regression of clinical manifestations, as well as improvement of quality of life indicators were proved. It has been established that the therapeutic effect of the complex application of Nucleo CMF forte and interference therapy lies in the improvement in the afferent and efferent links of the neuromotor apparatus, as well as the functional state of the spinal alpha-motoneurons associated with the acceleration of the regenerative processes. Activation of regenerative processes can also be associated with the restoration of certain morphological elements of the nervous system under the action of Nucleo CMF forte, as well as the normalization of the synthesis of complex lipids involved in cellular metabolism and synthesis of substances for the structural restoration of peripheral nerves. Carrying out neurotropic pharmacotherapy in combination with physiotherapy helps optimize therapeutic tactics in patients with vertebrogenic radiculopathies and is aimed at improving the quality of treatment, reducing the using of number of non-steroidal anti-inflammatory drugs and the frequency of relapse of the disease, and improving the quality of life of patients.


2021 ◽  
Vol 3 (3) ◽  
pp. 52-54
Author(s):  
Mamdouh H. Kalakatawi ◽  
Nusrat Aziz ◽  
Norhan A. K. Mostafa

Stiffperson syndrome (SPS) is one of the rarest neurological disorders. It is an autoimmune disease with antibodies against glutamic acid decarboxylase - enzyme needed to produce neurotransmitter GABA. This disease is very debilitating and fatal if not managed in time. A 32-year-old man presented with stiffness of abdominal and thoracolumbar paraspinal muscles first noticed 10 months back. There was history of jerkiness of hands. After excluding other mimicking conditions like multiple sclerosis, parkinsonism and axial dystonia, a diagnosis of Stiffperson syndrome was made. Treatment with IVIG therapy along with anti-spasticity drugs resulted in improved patient outcome. SPS is potentially treatable though cannot be cured. Not one treatment fits all patients with SPS and may have to be tailored according to the clinical manifestations. Increasing awareness in medical doctors and identifying the disease early can help the patients escape the disabling effects of SPS and improve the quality of life.


Author(s):  
G. Chupryna ◽  
N. Svyrydova ◽  
T. Parnikoza ◽  
A. Galusha ◽  
А. Popov

We studied the prevalence and characteristics of the disorders of the pelvic organs (DPO) in patients with multiple sclerosis (MS) in the aspect of comorbidity. The study involved 216 MS patients with different forms of course. It was found that the average prevalence DPO in the study group was 86.6%. The most closely DPO MS patients correlated with disease duration, level of disability (EDSS), female gender, level of fatigue and quality of life indicators. In the group of MS patients with comorbid pathology holds a significant prevalence of symptoms DPO and combined forms DPO. It was found that the use of acupuncture techniques in MS patients allows more effectively treat the symptoms DPO.


2011 ◽  
Vol 63 (3) ◽  
pp. 617-622 ◽  
Author(s):  
Svetlana Miletic ◽  
Gordana Toncev ◽  
Jasna Jevdjic ◽  
B. Jovanovic ◽  
D. Canovic

The aim of this work was to examine the relationship between fatigue and depression, common features of multiple sclerosis (MS), and the quality of life (QOL). The study was comprised of 120 patients with clinical manifestations of definite MS. Relapsing-remitting MS was present in 76.7% patients and secondary progressive MS was present in 23.3% patients. Mean disease duration was 8.1 ? 5.6 years and the mean Expanded Disability Status Score (EDSS) was 3.5 ? 1.8 (range 1-8). Fatigue was measured with the Fatigue Severity Scale (FSS), depression was measured by the Beck Depression Inventory (BDI) and QOL was assessed using the health-related quality of life questionnaire SF-36. We observed that the global FSS score was 4.6 ? 1.8 (range 1-7) and BDI was 10.7 ? 10.3 (range 0-39). The FSS significantly and positively correlated with the BDI scores (r = 0.572; p = 0.000). The severity of fatigue had a significant impact on the quality of life (r = -0.743; p = 0.000), in particular on mental health (r = -0.749; p = 0.000). We observed a significant correlation between the severity of depression and impaired quality of life (r = -0.684; p = 0.000). This study shows that fatigue and depression are associated with impaired QOL in MS.


2018 ◽  
Author(s):  
Karin Storm van's Gravesande ◽  
Elke Kalbe ◽  
Astrid Blaschek ◽  
Pasquale Calabrese ◽  
Josef Kessler ◽  
...  

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