scholarly journals Using Stelfrine supra 2.5% for children with accommodation and refraction disabilities

2021 ◽  
Vol 14 (2) ◽  
pp. 85-90
Author(s):  
Valeria L. Pekerskaya ◽  
Ekaterina V. Zhuravleva
Keyword(s):  
Visual Acuity ◽  
Study Groups ◽  
Subjective Assessment ◽  
Negative Part ◽  
Uncorrected Visual Acuity ◽  
Group 2 ◽  
Group 1

AIM:To assess the effect of Stelfrin supra (phenylephrine 2.5%) on the condition of accommodation, refraction and evaluate subjective comfort in instillation and adolescents with various refractive disorders. MATERIALS AND METHODS:Examined 45 people with mild emmetropia and hyperopia with symptoms of habitual excess tension of accommodation (15 people), with mild myopia (15 people), with moderate myopia (15 people) at the age of 7 to 16 years. Visometry, autorefractometry, assessment of the volume of absolute accommodation (positive and negative parts), subjective assessment of asthenopic complaints according to the OSDI scale were carried out before and 1 month after daily instillations of Stelfrin supra (phenylephrine 2.5%). RESULTS:After 1 month of instillation of the Stelfrin supra, the manifestations of accommodative asthenopia in the vast majority of patients in the study groups decreased, the habitual tonus of accommodation decreased, the volume of absolute accommodation increased, most significantly its negative part. The uncorrected visual acuity increased by 31% in patients of group 1 with emmetropia and mild hyperopia with habitually excessive tension of accommodation. The uncorrected visual acuity increased by 23% in patients of group 2 with mild myopia. An increase in the margin of relative accommodation was noted in patients of groups 1 and 2. Instillation of the drug was not accompanied by severe discomfort in the vast majority of patients. CONCLUSIONS:Stelfrin supra has shown its effectiveness in accommodating and refractive disorders in childhood and can be recommended in the treatment of children with accommodation disorders, asthenopia and mild to moderate myopia.

Topographically Guided Two-Step LASIK and Standard LASIK in the Correction of Refractive Errors after Penetrating Keratoplasty

2009 ◽  
Vol 19 (4) ◽  
pp. 535-543 ◽  
Author(s):  
Leopoldo Spadea ◽  
Massimo Saviano ◽  
Angela Di Gregorio ◽  
Domenico Di Lodovico ◽  
Fabio De Sanctis
Keyword(s):  
Visual Acuity ◽  
Penetrating Keratoplasty ◽  
Laser In Situ Keratomileusis ◽  
Refractive Errors ◽  
Manifest Refraction ◽  
Uncorrected Visual Acuity ◽  
The Mean ◽  
Group 2 ◽  
Group 1

Purpose To evaluate in a long-term period the effectiveness and safety of topographically guided two-step laser in situ keratomileusis (LASIK) and standard LASIK technique in the correction of refractive errors after successful penetrating keratoplasty (PKP) for keratoconus. Methods At least 2 years after PKP and 6 months after removal of all sutures, 15 eyes of 15 patients (Group 1; mean manifest refraction spherical equivalent (MRSE) −7.23 D ± 3.42 SD) were submitted to standard LASIK and 15 eyes of 15 patients (Group 2; mean MRSE −4.37 D ± 1.97 SD) to a topographically guided two-step LASIK procedure (first the flap and at least 2 weeks later the laser ablation). In all cases, a superior hinged corneal flap (160 μm/9.5 mm) was created. Results After a follow-up of 36 months, in Group 1 the mean uncorrected visual acuity (UCVA) was 0.51 logarithm of the minimum angle of resolution (logMAR) ± 0.41 SD and the mean best-corrected visual acuity (BCVA) was 0.03 logMAR ± 0.05 SD, with a mean MRSE of −1.57 D ± 2.65 SD. In Group 2, the mean UCVA was 0.28 logMAR ± 0.24 SD and the mean BCVA was 0.01 logMAR ± 0.03 SD, with a mean MRSE of −0.07 D ± 1.00 SD. In both groups, no complications were observed. Conclusions After a long follow-up period, both topographically guided two-step LASIK and standard LASIK could be considered effective and safe tools in the correction of refractive errors after successful PKP for keratoconus.

Femtosecond laser-assisted cataract surgery with RayOne trifocal lenses implantation

2021 ◽  
pp. 25-29
Author(s):  
M.M. Bikbov ◽  
◽  
O.I. Orenburkina ◽  
A.E. Babushkin ◽  
◽  
...  
Keyword(s):  
Visual Acuity ◽  
Surgical Treatment ◽  
Femtosecond Laser ◽  
Cataract Surgery ◽  
Subjective Assessment ◽  
Lighting Conditions ◽  
Trifocal Iol ◽  
Group 2 ◽  
Bifocal Lenses ◽  
Group 1

Purpose. To study the results of femtosecond laser-assisted cataract surgery (FLACS) using RayOne diffractive trifocal IOLs in comparison with bifocal lenses. Material and methods. The patients were divided into 2 groups: the first group included 32 patients (46 eyes) who were implanted with a bifocal refractive IOL M-flex 630 F with +3 dptr addidation during FPCS. The second group consisted of 34 people (49 eyes) with implanted RayOne trifocal IOL. The surgical treatment was evaluated by determining uncorrected visual acuity (UCVA) in the distance, at close (30-45 cm) and medium distance (50-70 cm) at discharge, 1 month and six months after the operation in photopic and mesopic lighting conditions, with the study of postoperative refractometry data, the construction of a defocusing curve, and subjective assessment of patient satisfaction. Results. A month after tthe operation the postoperative spheroequivalent in the range of ±0.5 D was achieved in group 1 in 82.6% of cases and in group 2-in 91.8. Six months after surgery near visual acuity without correction in photopic and mesopic light conditions was on average 0.61±0.08, while in patients of group 2, the average values were recorded at 0.64±0.09 and 0.62±0.07, respectively. By this time, the patients of group 1 had significantly lower rates of UCVA at long and medium distances: 0.81±0.08 in photopic lighting conditions and 0.79±0.08 in mesopic conditions, and group 2 0.41±0.08 and 0.40±0.10, respectively. Conclusion. Patients who underwent FLACS with an implanted RayOne trifocal IOL, compared with patients with bifocal IOLs, had higher rates of subjective satisfaction with the results of surgical treatment and UCVA at various distances (including greater comfort with actions performed at close and medium distances) at different light levels. Key words: multifocal IOLs, femtosecond laser-assisted cataract surgery, RayOne Trifocal.

Accelerated Corneal Crosslinking for Treatment of Progressive Keratoconus in Pediatric Patients

2016 ◽  
Vol 27 (3) ◽  
pp. 319-325 ◽  
Author(s):  
Döndü M. Ulusoy ◽  
Emre Göktaş ◽  
Necati Duru ◽  
Ayşe Özköse ◽  
Mustafa Ataş ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Pediatric Patients ◽  
Corneal Thickness ◽  
Efficacy And Safety ◽  
Ultraviolet A ◽  
Corneal Crosslinking ◽  
Corrected Visual Acuity ◽  
Uncorrected Visual Acuity ◽  
Group 2 ◽  
Group 1

Purpose To evaluate the safety and efficacy of accelerated corneal crosslinking (CXL) in patients with progressive keratoconus aged 18 years or less. Methods A total of 28 eyes from 19 patients with progressive keratoconus aged 18 years or less were enrolled. We divided participants into 2 groups according to corneal thickness (CT). Group 1 included 13 eyes of 8 patients with CT ≥450 µm; group 2 included 15 eyes of 11 patients with CT <450 µm. Each participant underwent accelerated CXL using 10-minute ultraviolet A irradiance at 9 mW/cm2 for a total energy dose of 5.4 J/cm2. The efficacy and safety of the procedure were assessed postoperatively at 1, 3, 6, and 12 months with Pentacam and visual acuity. Results In uncorrected visual acuity, group 1 showed a statistically significant +0.12 logMAR improvement at 3 months postoperatively (p = 0.003), and in group 2, there was a statistically significant +0.3 logMAR improvement at 1 month postoperatively (p = 0.005). In best-corrected visual acuity, there was a +0.15 logMAR (p<0.001) and +0.22 logMAR (p = 0.005) improvement in group 1 and group 2, respectively, at 12 months postoperatively. All mean keratometric values including K1 and K2 dropped by at least 1 D or remained stable (< ± 1 D) in both groups after accelerated CXL treatment. Conclusions The findings showed that accelerated CXL treatment seems to be effective in slowing or halting the progression of keratoconus and that no permanent apparent complications are noted 6 months after accelerated CXL.

scholarly journals Evaluation of Gingival Microleakage in Class II Composite Restorations with Different Lining Techniques: An In Vitro Study

Scientifica ◽  
2015 ◽  
Vol 2015 ◽  
pp. 1-6
Author(s):  
Vedavathi Bore Gowda ◽  
B. V. Sreenivasa Murthy ◽  
Swaroop Hegde ◽  
Swapna Devarasanahalli Venkataramanaswamy ◽  
Veena Suresh Pai ◽  
...  
Keyword(s):  
Study Groups ◽  
Class Ii ◽  
Composite Liner ◽  
Flowable Composite ◽  
Composite Restorations ◽  
Group 4 ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

Aim. To compare the microleakage in class II composite restorations without a liner/with resin modified glass ionomer and flowable composite liner.Method. Forty standardized MO cavities were prepared on human permanent mandibular molars extracted for periodontal reasons and then divided into 4 groups of ten specimens. The cavity preparations were etched, rinsed, blot dried, and light cured and Adper Single Bond 2 is applied. Group 1 is restored with Filtek P60 packable composite in 2 mm oblique increments. Group 2 is precure group where 1 mm Filtek Z350 flowable liner is applied and light cured for 20 sec. Group 3 is the same as Group 2, but the liner was cocured with packable composite. In Group 4, 1 mm RMGIC, Fuji Lining LC is applied and cured for 20 sec. All the teeth were restored as in Group 1. The specimens were coated with nail varnish leaving 1 mm around the restoration, subjected to thermocycling, basic fuchsin dye penetration, sectioned mesiodistally, and observed under a stereomicroscope.Results. The mean leakage scores of the individual study groups were Group 1 (33.40), Group 2 (7.85), Group 3 (16.40), and Group 4 (24.35). Group 1 without a liner showed maximum leakage. Flowable composite liner precured was the best.

Changes in Higher Order Aberrations after Wavefront-Guided Prk for Correction of Low to Moderate Myopia and Myopic Astigmatism: Two-Year Follow-Up

2007 ◽  
Vol 17 (4) ◽  
pp. 507-514 ◽  
Author(s):  
D. Wygledowska-Promienska ◽  
I. Zawojska
Keyword(s):  
Visual Acuity ◽  
Excimer Laser ◽  
Spherical Aberration ◽  
Higher Order ◽  
Control Group ◽  
Higher Order Aberrations ◽  
Order Root ◽  
Group 2 ◽  
Myopic Astigmatism ◽  
Group 1

Purpose To assess efficacy, safety, and changes in higher order aberrations after wavefront-guided photorefractive keratectomy (PRK) in comparison with conventional PRK for low to moderate myopia with myopic astigmatism using a WASCA Workstation with the MEL 70 G-Scan excimer laser. Methods A total of 126 myopic or myopic-astigmatic eyes of 112 patients were included in this retrospective study. Patients were divided into two groups: Group 1, the study group; and Group 2, the control group. Group 1 consisted of 78 eyes treated with wavefront-guided PRK. Group 2 consisted of 48 eyes treated with spherocylindrical conventional PRK. Results Two years postoperatively, in Group 1, 5% of eyes achieved an uncorrected visual acuity (UCVA) of 0.05; 69% achieved a UCVA of 0.00; 18% of eyes experienced enhanced visual acuity of −0.18 and 8% of −0.30. In Group 2, 8% of eyes achieved a UCVA of 0.1; 25% achieved a UCVA of 0.05; and 67% achieved a UCVA of 0.00 according to logMAR calculation method. Total higher-order root-mean square increased by a factor 1.18 for Group 1 and 1.6 for Group 2. There was a significant increase of coma by a factor 1.74 in Group 2 and spherical aberration by a factor 2.09 in Group 1 and 3.56 in Group 2. Conclusions The data support the safety and effectiveness of the wavefront-guided PRK using a WASCA Workstation for correction of low to moderate refractive errors. This method reduced the number of higher order aberrations induced by excimer laser surgery and improved uncorrected and spectacle-corrected visual acuity when compared to conventional PRK.

scholarly journals Characterization of Enamel After the Use of Oral Hygiene Auxiliaries with Whiteners

2019 ◽  
pp. 227-236
Author(s):  
Norma Verónica Zavala-Alonso DDS, MSc, PhD ◽  
Jorge Humberto Ramírez-González DDS, MSc ◽  
Mariana Ramírez-Vergara DDS ◽  
José Gilberto Roque-Márquez DDS, MSc ◽  
Flores Daniel Silva-Herzog DDS, MSc, PhD
Keyword(s):  
Oral Hygiene ◽  
Dental Enamel ◽  
Hardness Test ◽  
Study Groups ◽  
Micro Hardness ◽  
Sem Images ◽  
Group 4 ◽  
Group 2 ◽  
Mouth Wash ◽  
Group 1

The purpose of this study was to evaluate the effect of the use of the combined auxiliaries of oral hygiene with whitening agents on the micro-hardness and micro-morphology of dental enamel. Materials and Methods. 40 human incisors were used and sectioned to obtain 4x4mm samples and divided into four study groups. Group 1: Electric brushing with Toothpaste (BTP); Group 2: Electric brushing with Toothpaste+mouthwash (BTP+MW); Group 3: Electric brushing with Toothpaste+whitening pen (BTP+WP); Group 4: Electric brushing with Toothpaste+mouth wash+whitening pen (BTP+MW+WP). Samples were submitted toVickers micro-hardness test and visualized using scanning electron microscopy (SEM). Results. All groups, with the exception of group 1, showed a decrease in micro-hardness values after applying the treatments (p<0.05). Likewise, when comparing the values after the treatments between the groups, significant statistical differences were found in all of comparisons except for those of groups 2 and 4. SEM images showed changes in the morphology in all the study groups with the exception of group 1. Conclusion. Significant changes such as decrease in micro-hardness as well as in the topography of the enamel surface such as elevations, craters, porosities and etching patterns were founded after the use of the combination of auxiliaries of oral hygiene with whitening agents.  

scholarly journals Reconstructing Foveola by Foveolar Internal Limiting Membrane Non-Peeling and Tissue Repositioning for Lamellar Hole-Related Epiretinal Proliferation

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Tzyy-Chang Ho ◽  
Allen Yi-Lun Ho ◽  
Muh-Shy Chen
Keyword(s):  
Visual Acuity ◽  
Clinical Characteristics ◽  
Internal Limiting Membrane ◽  
Lamellar Macular Hole ◽  
Ilm Peeling ◽  
Corrected Visual Acuity ◽  
Tangential Traction ◽  
Group 2 ◽  
Lamellar Hole ◽  
Group 1

Abstract Differences in the pathogenesis and clinical characteristics between lamellar macular hole (LMH) with and without LMH-associated epiretinal proliferation (LHEP) can have surgical implications. This study investigated the effects of treating LHEP by foveolar internal limiting membrane (ILM) non-peeling and epiretinal proliferative (EP) tissue repositioning on visual acuity and foveolar architecture. Consecutive patients with LHEP treated at our institution were enrolled. The eyes were divided into a conventional total ILM peeling group (group 1, n = 11) and a foveolar ILM non-peeling group (group 2, n = 22). In group 2, a doughnut-shaped ILM was peeled, leaving a 400-μm-diameter ILM without elevated margin over the foveola after EP tissue repositioning. The EP tissue was elevated, trimmed, and inverted into the LMH. Postoperatively, the LMH was sealed in all eyes in group 2, with significantly better best-corrected visual acuity (−0.26 vs −0.10 logMAR; p = 0.002). A smaller retinal defect (p = 0.003), a more restored ellipsoid zone (p = 0.002), and a more smooth foveal depression (p < 0.001) were achieved in group 2. Foveolar ILM non-peeling and EP tissue repositioning sealed the LMH, released the tangential traction, and achieved better visual acuity. The presumed foveolar architecture may be reconstructed surgically. LMH with LHEP could have a combined degenerative and tractional mechanism.

scholarly journals Treatment of Optic Canal Decompression Combined with Umbilical Cord Mesenchymal Stem (Stromal) Cells for Indirect Traumatic Optic Neuropathy: A Phase 1 Clinical Trial

2020 ◽  
Vol 64 (3) ◽  
pp. 398-404
Author(s):  
Jia Li ◽  
Xu Bai ◽  
Xiaoyue Guan ◽  
Hongfeng Yuan ◽  
Xiang Xu
Keyword(s):  
Visual Acuity ◽  
Adverse Events ◽  
Phase 1 ◽  
Optic Canal ◽  
Traumatic Optic Neuropathy ◽  
Corrected Visual Acuity ◽  
Group 2 ◽  
Best Corrected Visual Acuity ◽  
Group 1

<b><i>Purpose:</i></b> This study was aimed to investigate the safety and feasibility of umbilical cord-derived mesenchymal stem cell (MSC) transplantation in patients with traumatic optic neuropathy (TON). <b><i>Methods:</i></b> This is a single-center, prospective, open-labeled phase 1 study that enrolled 20 patients with TON. Patients consecutively underwent either optic canal decompression combined with MSC local implantation treatment (group 1) or only optic canal decompression (group 2). Patients were evaluated on the first day, seventh day, first month, third month, and sixth month postoperatively. Adverse events, such as fever, urticarial lesions, nasal infection, and death, were recorded at each visit. The primary outcome was changes in best-corrected visual acuity. The secondary outcomes were changes in color vision, relative afferent pupillary defect, and flash visual evoked potential. <b><i>Results:</i></b> All 20 patients completed the 6-month follow-up. None of them had any systemic or ocular complications. The change in best-corrected visual acuity at follow-up was not significantly different between group 1 and group 2 (<i>p</i> &#x3e; 0.05); however, group 1 showed better visual outcome than group 2. Both groups showed significant improvements in vision compared with the baseline (<i>p</i> &#x3c; 0.05); however, there were no statistically significant differences between the groups (<i>p</i> &#x3e; 0.05). In addition, no adverse events related to local transplantation were observed in the patients. <b><i>Conclusions:</i></b> A single, local MSC transplantation in the optic nerve is safe for patients with TON.

Comparison of Visual Outcomes after Bilateral Implantation of Extended Range of Vision and Trifocal Intraocular Lenses

2017 ◽  
Vol 27 (4) ◽  
pp. 460-465 ◽  
Author(s):  
Ramón Ruiz-Mesa ◽  
Antonio Abengózar-Vela ◽  
Ana Aramburu ◽  
María Ruiz-Santos
Keyword(s):  
Visual Acuity ◽  
Contrast Sensitivity ◽  
Intraocular Lenses ◽  
Patient Questionnaire ◽  
Visual Outcomes ◽  
Uncorrected Distance Visual Acuity ◽  
Extended Range ◽  
Near Visual Acuity ◽  
Group 2 ◽  
Group 1

Purpose To compare visual outcomes after cataract surgery with bilateral implantation of 2 intraocular lenses (IOLs): extended range of vision and trifocal. Methods Each group of this prospective study comprised 40 eyes (20 patients). Phacoemulsification followed by bilateral implantation of a FineVision IOL (group 1) or a Symfony IOL (group 2) was performed. The following outcomes were assessed up to 1 year postoperatively: binocular uncorrected distance visual acuity (UDVA), binocular uncorrected intermediate visual acuity (UIVA) at 60 cm, binocular uncorrected near visual acuity (UNVA) at 40 cm, spherical equivalent (SE) refraction, defocus curves, mesopic and photopic contrast sensitivity, halometry, posterior capsule opacification (PCO), and responses to a patient questionnaire. Results The mean binocular values in group 1 and group 2, respectively, were SE -0.15 ± 0.25 D and -0.19 ± 0.18 D; UDVA 0.01 ± 0.03 logMAR and 0.01 ± 0.02 logMAR; UIVA 0.11 ± 0.08 logMAR and 0.09 ± 0.08 logMAR; UNVA 0.06 ± 0.07 logMAR and 0.17 ± 0.06 logMAR. Difference in UNVA between IOLs (p<0.05) was statistically significant. There were no significant differences in contrast sensitivity, halometry, or PCO between groups. Defocus curves were similar between groups from 0 D to -2 D, but showed significant differences from -2.50 D to -4.00 D (p<0.05). Conclusions Both IOLs provided excellent distance and intermediate visual outcomes. The FineVision IOL showed better near visual acuity. Predictability of the refractive results and optical performance were excellent; all patients achieved spectacle independence. The 2 IOLs gave similar and good contrast sensitivity in photopic and mesopic conditions and low perception of halos by patients.

A numerical analysis of major groupings in Medicago employing traditionally used characters

1981 ◽  
Vol 59 (9) ◽  
pp. 1553-1577 ◽  
Author(s):  
Ernest Small
Keyword(s):  
Numerical Analysis ◽  
Study Groups ◽  
Species Group ◽  
Annual Species ◽  
Agglomerative Clustering ◽  
Medicago Arborea ◽  
Group 3 ◽  
Group 2 ◽  
Numerical Examination ◽  
Group 1

Numerical taxonomic analyses (particularly agglomerative clustering and ordination) were conducted on 55 species of Medicago, using 75 mostly vegetative and fruiting characters. The material studied represents all conservatively accepted species of the genus, as well as 14 "problematical" species of which many are often considered to belong to the genus Trigonella, rather than to Medicago. Although the characters employed are substantially the same as those used by recent monographers who evaluated the genus by traditional subjective procedures, the present numerical examination suggests many relationships not previously appreciated.As a result of the analyses, it was judged appropriate to recognize 12 groupings. These are group 1: M. sativa (alfalfa) and 11 allied species; group 2: M. lupulina and M. secundiflora; group 3: eight problematical species which have troubled taxonomists with respect to whether they should be placed in Medicago or Trigonella; groups 4–8: each made up of a single divergent species, respectively: M. carstiensis, M. radiata, M. orbicularis, M. heyniana, and M. arborea; groups 9–12 four subgroupings of a larger group of 28 annual species. In the main, the composition of the seven polytypic groups is similar to those of taxa accepted by recent monographers, although some realignments of particular species are suggested by the present study. Groups 1 and 2 are much more similar to each other than indicated in recent treatments. Medicago arborea was discovered to be much more dissimilar to all other species examined than thought previously. Medicago hybrida of group 1 was found to be a "master link" between species traditionally placed in Medicago, and many placed in Trigonella (group 3).The 12 groupings in turn fall into three assemblages that could be recognized as subgenera, or even as genera. These are A: groups 1, 2, 9, 10, 11, and 12; B: groups 3–7, inclusive; and C: M. arborea. Further research is suggested before formal categorization is undertaken.

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